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Abstracts tagged "Decision analysis"

  • Abstract Number: 0396 • ACR Convergence 2026

    Performance of the DUET ultrasound enthesitis score in a real-world setting as a diagnostic tool in early PsA: An external validation prospective cohort study (PREDICT Study)

    Sahil Koppikar1, Liana Dimitropoulos2, Fahmeen Afgani3 and Lihi Eder4 Affiliations: 1Women's College Hospital & University of Toronto, Thornhill, ON, Canada, 2Women's College Research Institute, Toronto, ON, Canada, Toronto, ON, Canada, 3Women's College Hospital, Toronto, ON, Canada, Toronto, Canada, 4Women's College Hospital, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Diagnostic delay remains a major challenge in psoriatic arthritis (PsA), in part due to the lack of reliable tools to distinguish PsA from other…
  • Abstract Number: 1448 • ACR Convergence 2026

    Improving recognition of multisystem complications in rheumatoid arthritis: Can generative AI bridge the clinical gap?

    Man Han1, Qiuwei Peng1, Mengge Song1, Yanting Li1, Weifeng Zhang1, Buqing Lu1, Yaya Ding2, Ruobing Han3, Yu Huang4, Lu Tian5, Anjun Chen3 and Quan Jiang1 Affiliations: 1Department of Rheumatology, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China (People's Republic), 2Department of Tranditional Chinese Medicine, Qinghai Unversity Medical College, Xining, China (People's Republic), 3ELHS Institute, Palo Alto, 4Peking University, Beijing, China (People's Republic), 5Stanford University, Stanford

    Background/Purpose: Recognition of multisystem complications in rheumatoid arthritis (RA) is often incomplete in routine care, particularly for complex, uncommon, or rare diseases (CURDs). We evaluated…
  • Abstract Number: 1686 • ACR Convergence 2026

    Agreement Between Commercial Artificial Intelligence and Expert Capillaroscopist in Nailfold Capillary Density Assessment: A Two-Center Validation Study

    Genessis Maldonado1, Jonathan Gerwien2, Ramona Govender3, Maurizio Cutolo4, Tracy Frech5 and Vanessa Smith6 Affiliations: 1Vanderbilt University Medical Center, Nashville, TN, 2Vanderbilt University, Nashville, 3Ghent University Hospital, Guent, Belgium, 4University of Genova, Genova, Genoa, Italy, 5Vanderbilt Health, Nashville, TN, 6Ghent University Hospital, Gent, Belgium

    Background/Purpose: Nailfold videocapillaroscopy (NVC) is essential in systemic sclerosis (SSc) evaluation. Capillary density (capillaries/mm) is a key quantitative parameter for clinical trials. AI-based platforms have…
  • Abstract Number: 1719 • ACR Convergence 2026

    Development and Validation of an Interactive Chatbot as a Screening Tool for Inflammatory Arthritis : A Single-Centre Pilot Study

    Tanmay Lorance Peter1, Aditya Raj2, Anna Das3 and Vineeta Shobha4 Affiliations: 1M S Ramaiah Medical College, Bangalore, Karnataka, India, 2National Public School, Bangalore, Karnataka, India, 3St John's Medical College, Bangalore, Karnataka, India, 4St John's Medical College, Bengaluru, Bengaluru, Karnataka, India

    Background/Purpose: Inflammatory arthritis (IA) poses a significant diagnostic challenge at the primary care level, causing delayed institution of effective pharmacotherapy. A population-based screening strategy for…
  • Abstract Number: 1960 • ACR Convergence 2026

    Amplification of the Th17/IL-17 Pathway Activation Marks the Transition from Very Early Systemic Sclerosis (VEDOSS) to Established Systemic Sclerosis: A Multi-Omics Analysis

    Justus Ohmes1, Hanna Graßhoff2, Sara Comdühr2, Aderiike Babarinsa2, Felix Sajon2, Harald Heidecke3, Timo Gemoll2, Antje Müller2, Kathrin Kalies2, Reza Akbarzadeh2, Gabriela Riemekasten2 and Jens Humrich2 Affiliations: 1University of Lübeck, Lübeck, Schleswig-Holstein, Germany, 2University of Lübeck, Lübeck, Germany, 3Celltrend Inc., Luckenwalde, Germany

    Background/Purpose: Systemic sclerosis (SSc) carries the highest mortality among rheumatic diseases, underscoring the need to identify immunological drivers before irreversible organ damage occurs. The Very…
  • Abstract Number: 2260 • ACR Convergence 2026

    LupusBench: A Mixed-Format Benchmark for Evaluating Large Language Models in Systemic Lupus Erythematosus – A Pilot Study

    Alexandre Lima Matos, Emilia Inoue Sato, Antonio Silaide De Araujo Junior, Jhonatan Costa Messias, Gabriela Amorim Mattos, Thiago Alberto Fernandes Gomes dos Santos and Edgard Torres dos Reis-Neto Affiliations: Rheumatology Divison, Department of Medicine, Escola Paulista de Medicina / Universidade Federal de São Paulo, São Paulo, Brazil

    Background/Purpose: Medical large language model benchmarks are essential for standardizing task performance, scoring procedures, and safety assessments. Broad medical benchmarks, including MultiMedQA/Med-PaLM, HealthBench, MedHELM, and…
  • Abstract Number: 2454 • ACR Convergence 2026

    Clinical Accuracy, Safety and Completeness of Large Language Models for Pregnancy, Family Planning and Lactation Counseling in Inflammatory Rheumatic Diseases: An Expert-Rated Comparative Study

    Maria Polyzou1, Xenofon Baraliakos2 and Diana Vossen3 Affiliations: 1Department of Pathophysiology, School of Medicine, Laiko General Hospital, National and Kapodistrian University of Athens, Athens, Greece, 2Ruhr University Bochum, Rheumazentrum Ruhrgebiet, Bochum, Herne, Germany, 3Ruhruniversity Bochum, Rheumazentrum Ruhrgebiet, Düsseldorf, Nordrhein-Westfalen, Germany

    Background/Purpose: The rate of integration and use of Large Language Models (LLMs) in the diagnosis and treatment of inflammatory rheumatic diseases (iRMD) has shown a…
  • Abstract Number: 2661 • ACR Convergence 2026

    From Assessment to Action: Physician Global Assessment and Treatment Escalation in Inflammatory Arthritis

    Gozde Sevgi Kart Bayram1, Gizem Ayan2, Levent Kılıc2 and Umut Kalyoncu1 Affiliations: 1Division of Rheumatology, Department of Internal Medicine, Hacettepe University School of Medicine, Ankara, Turkey; Hacettepe University Vasculitis Research Center (HUVAC), Ankara, Turkey, Ankara, Ankara, Turkey, 2Division of Rheumatology, Department of Internal Medicine, Hacettepe University School of Medicine, Ankara, Turkey; Hacettepe University Vasculitis Research Center (HUVAC), Ankara, Turkey, Ankara, Turkey

    Background/Purpose: Physician Global Assessment (PhGA) is widely used to assess disease activity in inflammatory arthritis and often guides treatment decisions. However, the PhGA threshold associated…
  • Abstract Number: 2718 • ACR Convergence 2026

    Cost-effectiveness Analysis of Screening for Antimalarial-induced Cardiomyopathy in Systemic Lupus Erythematosus Patients on Hydroxychloroquine

    Cassidy Sun1, Andrea Luviano2, Youngmin Kim3, Ankur Pandya2, Elena Losina4 and Karen Costenbader5 Affiliations: 1Harvard T.H. Chan School of Public Health, Boston, MA, 2Harvard T.H. Chan School of Public Health, Boston, 3Brigham and Women's Hospital, Boston, MA, 4BWH, Boston, MA, 5Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA, BOSTON, MA

    Background/Purpose: Hydroxychloroquine (HCQ) is prescribed in almost all patients with systemic lupus erythematosus (SLE). Antimalarial-induced cardiomyopathy (AMIC) is a rare but life-threatening complication of long-term…
  • Abstract Number: 2933 • ACR Convergence 2026

    Large-Scale Plasma Proteomics Identifies Orosomucoid 1 as a Circulating Predictor of Difficult-to-Treat Rheumatoid Arthritis

    Jiri Baloun1, Klara Mocova2, Lucie Andrés Cerezo1, Tereza Kropackova1, Aneta Prokopcova3, Kristyna Brabnikova Maresova1, Herman Mann4, Jiri Vencovsky5, Karel Pavelka6 and Ladislav Senolt7 Affiliations: 1Institute Of Rheumatology, Prague, Czech Republic, 2Institute of Rheumatology, Melnik, Czech Republic, 3Institute of Rheumatology, Prague, Czechia, Prague, Czech Republic, 4Revmatologický Ústav, Praha 2, Czech Republic, 5Institute of Rheumatology, Praha 8, Czech Republic, 6Institute of Rheumatology, Prague, Czechia; First Faculty of Medicine, Charles University, Prague, Czechia, Praha, Czech Republic, 7Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czechia, Praha, Czech Republic

    Background/Purpose: Despite biologic (b) and targeted synthetic (ts) disease-modifying antirheumatic drugs (DMARDs), approximately 10.9% of rheumatoid arthritis (RA)1 patients meet the EULAR definition of difficult-to-treat…
  • Abstract Number: 0449 • ACR Convergence 2025

    Consistency of CDAI Low-Disease Activity (LDA) Outcomes with Time in a Large US Registry: Association With Patient-Reported Clinical Outcomes and Measures of Quality of Life

    Joel Kremer1, Kevin Kane2, George Reed3 and Michael Weinblatt4, 1The Corrona Research Foundation, Delray Beach, FL, 2U of Mass Medical School, Worcester, MA, MA, 3University of Massachusetts Chan Medical School, Worcester, MA, 4Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Low disease activity has been identified as a treatment goal for the treatment of RA. A singlecenter RA registry (BRASS) reported a difference in…
  • Abstract Number: 1050 • ACR Convergence 2025

    Bridging the Gap: A Mixed-Methods Study to Enhance Integration of HCQ-SAFE, A Shared Decision-Making Tool for Hydroxychloroquine Use, in Routine Lupus Care

    Isabella Hartel1, Jay Patel1, David Gazeley2, Drake Johnson1, Justin Levinson1, Carmen Campbell1, Britney Youngchild3, Shelby Gomez3, Amannda Weber4, Jessica Michaud5, Laura Dickmann6, Sancia Ferguson7, Betty Chewning8, Christie Bartels9 and Shivani Garg10, 1University of Wisconsin, School of Medicine and Public Health, Madison, Madison, WI, 2Medical College of Wisconsin, Milwaukee, WI, 3University of Wisconsin, School of Pharmacy, Madison, WI, 4University of Wisconsin (UW), UW Health, Madison, WI, 5Medical College of Wisconsin, Milwaukee, Madison, WI, 6Medical College of Wisconsin, Milwaukee, Milwaukee, 7University of Wisconsin School of Medicine and Public Health, Madison, Madison, WI, 8University of Wisconsin, School of Pharmacy, Madison, 9University of Wisconsin School of Medicine and Public Health, Madison, WI, 10University of Madison, School of Medicine and Public Health, Madison, WI

    Background/Purpose: Hydroxychloroquine (HCQ) is a key therapy for lupus (or SLE). Yet, challenged to weigh benefits vs. harms, ~80% of patients self-discontinue HCQ. Shared decision-making…
  • Abstract Number: 1051 • ACR Convergence 2025

    Mitigating Hydroxychloroquine (HCQ) Nonadherence by Clarifying Misbeliefs Using a Shared Decision-Making Tool (HCQ-SAFE©) Across Two Different Rheumatology Centers

    Isabella Hartel1, David Gazeley2, Jay Patel1, Betty Chewning3, Shelby Gomez4, Jessica Michaud5, Laura Dickmann6, Jon keevil7, Patricia Tellez-giron1, Christie Bartels8 and Shivani Garg9, 1University of Wisconsin, School of Medicine and Public Health, Madison, Madison, WI, 2Medical College of Wisconsin, Milwaukee, WI, 3University of Wisconsin, School of Pharmacy, Madison, 4University of Wisconsin, School of Pharmacy, Madison, WI, 5Medical College of Wisconsin, Milwaukee, Madison, WI, 6Medical College of Wisconsin, Milwaukee, Milwaukee, 7N/A, Madison, 8University of Wisconsin School of Medicine and Public Health, Madison, WI, 9University of Madison, School of Medicine and Public Health, Madison, WI

    Background/Purpose: Hydroxychloroquine (HCQ) prolongs disease-free and damage-free survival in lupus (SLE). Yet, ~80% of patients stop taking HCQ resulting in poor outcomes including early mortality.…
  • Abstract Number: 1052 • ACR Convergence 2025

    “Prednisone… A Necessary Evil…” Developing an Evidence-Based Benefits vs. Harms Shared Decision-Making Tool (PRED-SAFE) to Support Decisions Around Chronic Prednisone Use

    Isabella Hartel1, Jay Patel1, Justin Levinson1, Sancia Ferguson2, Carmen Campbell1, Amannda Weber3, Shelby Gomez4, David Gazeley5, Ali Duarte-Garcia6, Jennifer Barton7 and Shivani Garg8, 1University of Wisconsin, School of Medicine and Public Health, Madison, Madison, WI, 2University of Wisconsin School of Medicine and Public Health, Madison, Madison, WI, 3University of Wisconsin (UW), UW Health, Madison, WI, 4University of Wisconsin, School of Pharmacy, Madison, WI, 5Medical College of Wisconsin, Milwaukee, WI, 6Mayo Clinic, Rochester, MN, 7VA Portland Health Care System/OHSU, Portland, OR, 8University of Madison, School of Medicine and Public Health, Madison, WI

    Background/Purpose: Guidelines recommend limiting chronic prednisone use ( >5 mg/d for >3-6 mos.) given higher risks of fractures, infections, and damage. Yet, patients struggle to…
  • Abstract Number: 1186 • ACR Convergence 2025

    Increased Adoption of IL-1 Pathway Inhibition and the Steroid-sparing Paradigm Shift: Temporal Trends in Recurrent Pericarditis Treatment From the RESONANCE Patient Registry

    Paul Cremer1, Michael Garshick2, Sushil Allen Luis3, Ajit Raisinghani4, Brittany Weber5, Vidhya Parameswaran6, Allison Curtis6, Sue Gibbons6, Allan Klein7 and John Paolini6, 1Cleveland Clinic, Shaker Heights, OH, 2NYU Langone Health, Tenafly, NJ, 3Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, 4Division of Cardiology, Department of Medicine, Sulpizio Cardiovascular Center, University of California San Diego, San Diego, CA, 5Brigham and Women's Hospital, DEDHAM, MA, 6Kiniksa Pharmaceuticals, LEXINGTON, MA, 7Cleveland Clinic, Cleveland, OH

    Background/Purpose: Recurrent pericarditis (RP) is a chronic autoinflammatory disease mediated by IL-1 that requires long-term treatment. While the 2015 European Society of Cardiology Guidelines position…
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