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Abstracts tagged "Damage Index"

  • Abstract Number: 1602 • ACR Convergence 2022

    Fibroblast Activation Protein (FAP) PET-CT for Depicting Inflammatory Joint Damage in Patients with Psoriatic Arthritis

    Simon Rauber1, Hashem Mohammadian2, Chrstian Schmidkonz3, Armin Atzinger3, Maria Gabriella Raimondo1, Hannah Labinsky4, Christoph Treutlein2, Johannes Knitza1, Simone Maschauer2, Frank Roemer5, Olaf Prante2, Torsten Kuwert3, Juan Canete6, Georg Schett7 and Andreas Ramming1, 1Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-UniversityErlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, 2Friedrich-Alexander-University (FAU) Erlangen-Nürnberg, Erlangen, Germany, 3Friedrich-Alexander University (FAU) Erlangen-Nuremberg, Erlangen, Germany, 4Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, 5Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany, 6Unidad de Artritis Hospital Clinic, Barcelona, Spain, 7Universitätsklinikum Erlangen, Erlangen, Germany

    Background/Purpose: Psoriatic arthritis (PsA) is characterized by substantial mesenchymal tissue activation in the context of inflammation leading to structural damage. Measuring mesenchymal tissue activation in…
  • Abstract Number: 1877 • ACR Convergence 2022

    Nailfold Videocapillaroscopic Abnormalities Correlate with Disease Activity Measures and Cutaneous Damage in Patients with Idiopathic Inflammatory Myopathies

    Diane Zisa1, Aliza Bloostein1, Deanna Jannat-Khah, DrPH, MSPH1, Maurizio Cutolo2, Vanessa Smith3 and David Fernandez1, 1Hospital for Special Surgery, New York, NY, 2Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS San Martino Polyclinic Hospital, Genova, Italy, 3Department of Rheumatology, Ghent University Hospital – Department of Internal Medicine, Ghent University, Belgium – Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center (IRC), Gent, Belgium

    Background/Purpose: Nailfold videocapillaroscopy (NVC) is a non-invasive tool used to evaluate the microcirculation of patients with connective tissue diseases (CTDs). A specific combination of NVC…
  • Abstract Number: 2067 • ACR Convergence 2022

    Predictors of Organ Damage Accrual by Domains

    Rangi Kandane-Rathnayake1, Ning Li1, Vera Golder1, Worawit Louthrenoo2, Yi-Hsin Chen3, Jiacai Cho4, Aisha Lateef5, Laniyati Hamijoyo6, Luo Shue Fen7, Yeong-Jian Wu7, Sandra Navarra8, Leonid Zamora9, Zhanguo Li10, An Yuan11, Sargunan Sockalingam12, Yasuhiro Katsumata13, Masayoshi Harigai13, Yanjie Hao14, Zhouli Zhang15, Madelynn Chan16, Jun Kikuchi17, Tsutomu Takeuchi18, Shereen Oon19, Sang-Cheol Bae20, Fiona Goldblatt21, Sean O'Neill22, Kathy Gibson22, Kristine Ng23, Hui Nee Annie Law24, Duminda Basnayake25, Nicole Tugnet26, Sunil Kumar27, Cherica Tee28, Michael Tee28, Yoshiya Tanaka29, Chak Sing30, Mandana Nikpour31, Alberta Hoi32 and Eric Morand33, 1Monash University, Clayton, Australia, 2Chiang Mai University, Chiang Mai, Thailand, 3Taichung Veterans General Hospital, Taichung, Taiwan, 4National University Health System (NUHS), Singapore, Singapore, 5National University Hospital, Singapore, Singapore, 6Hasan Sadikin Hospital, Jakarta Selatan, Indonesia, 7Chang Gung Memorial Hospital, Taoyuan, Taiwan, 8University of Santo Tomas, Manila, Philippines, 9University of Santo Tomas Hospital, Manila, Philippines, 10People's Hospital, Peking University Health Science Center, Beijing, China, 11Peking University Health Science Center, Beijing, China, 12University of Malaya, Kuala Lumpur, Malaysia, 13Division of Rheumatology, Department of Internal Medicine, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan, 14The University of Melbourne, Melbourne, Australia, 15Peking University First Hospital, Beijing, China, 16Tan Tock Seng Hospital, Singapore, Singapore, 17Keio University, Tokyo, Japan, 18Keio University and Saitama Medical University, Tokyo, Japan, 19St Vincent's Hospital, Fitzroy, Australia, 20Hanyang University Medical Center, Seoul, Republic of Korea, 21Flinders Medical Centre, Adelaide, Australia, 22Liverpool Hospital, Sydney, Australia, 23North Shore Hospital, Auckland, New Zealand, 24Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore, 25Teaching Hospital Kandy, Kandy, Sri Lanka, 26Greenlane Clinical Centre, Auckland, New Zealand, 27Middlemore Hospital, Auckland, New Zealand, 28University of the Philippines, Quezon City, Philippines, 29University of Occupational and Environmental Health, Kitakyusyu Fukuoka, Japan, 30The University of Hong Kong, Pok Fu Lam, Hong Kong, 31The University of Melbourne at St. Vincent's Hospital Melbourne, Melbourne, Australia, 32Monash Health, Melbourne, Australia, 33Monash University, Victoria; Department of Rheumatology, Monash Health, Melbourne, Australia

    Background/Purpose: Prevention of organ damage is one of the main treatment goals in systemic lupus erythematosus (SLE).The SLICC/ACR Damage Index (SDI) is used to quantify…
  • Abstract Number: 2071 • ACR Convergence 2022

    The Systemic Lupus Erythematosus International Collaborating Clinics (SLICC), American College of Rheumatology (ACR), and Lupus Foundation of America (LFA) Damage Index Revision – Item Generation Phase

    Burak Kundakci1, Megan R W Barber2, Ann E Clarke2, Sindhu R. Johnson3, Hermine Brunner4, Jiacai Cho5, Nathalie Costedoat-Chalumeau6, Ellen M. Ginzler7, John Hanly8, Abida Hasan7, Murat İnanç9, Naureen Kabani7, Alexandra Legge10, Kaitlin Lima11, Livia Lindoso12, Anselm Mak13, Rosalind Ramsey-Goldman11, Guillermo Ruiz-Irastorza14, Clovis A. Silva12, Farah Tamirou15, Vitor C. Trindade12, Evelyne Vinet16 and Ian N. Bruce1, 1Centre for Epidemiology Versus Arthritis, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom, 2University of Calgary, Division of Rheumatology, Cumming School of Medicine, Calgary, AB, Canada, 3Division of Rheumatology, Department of Medicine, Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western and Mount Sinai Hospitals; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada, 4Division of Rheumatology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Department of Pediatrics, Cincinnati, OH, 5National University Health System (NUHS), Singapore, Singapore, 6Inserm DR Paris 5, Paris, France, 7SUNY Downstate Health Sciences University, Department of Medicine, Brooklyn, NY, 8Division of Rheumatology, Queen Elizabeth II Health Sciences Center (Nova Scotia Rehabilitation Site) and Dalhousie University, Halifax, NS, Canada, 9Istanbul University Faculty of Medicine, Istanbul, Turkey, 10Arthritis Research Canada, Dalhousie University, Halifax, NS, Canada, 11Northwestern University Feinberg School of Medicine, Chicago, USA, Chicago, IL, 12Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, Brazil, 13Division of Rheumatology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 14Autoimmune Diseases Research Unit, Biocruces Bizkaia Health Research Institute, Hospital Universitario Cruces, UPV/EHU, Barakaldo, Spain, 15Rheumatology department, Cliniques Universitaires Saint-Luc, Brussels, Belgium, 16McGill University Health Centre, Montréal, QC, Canada

    Background/Purpose: The SLICC, ACR and LFA embarked on a data- and expert-driven project to develop a revised systemic lupus erythematosus (SLE) organ damage index (SDI).…
  • Abstract Number: 2089 • ACR Convergence 2022

    The Implication of Skin Involvement on Health-Related Quality of Life (HRQoL) in Systemic Lupus Erythematosus (SLE) Patients

    Alicia Van1, Vibeke Strand2, Jiandong Su1, Nicole Anderson1, Cheryl F Rosen3, Sherief Marzouk4, Lee S Simon5 and Zahi Touma1, 1Schroeder Arthritis Institute, Krembil Research Institute, University Health Network and University of Toronto, Toronto, ON, Canada, 2Stanford University School of Medicine, Stanford, CA, 3University of Toronto, Toronto, ON, Canada, 4University Health Network, University of Toronto, Toronto, ON, Canada, 5SDG LLC, West Newton, MA

    Background/Purpose: Skin involvement in Systemic Lupus Erythematosus (SLE) occurs in 50-85% of patients making it one of the most commonly affected organs in SLE. Previous…
  • Abstract Number: PP17 • ACR Convergence 2022

    Engaging with the Spoon Theory: How I Make Decisions Using a Cost-Benefit Analysis That Works to Improve My Mental Health While Living with RA

    Stephanie Aleite, AiArthritis, St. Louis, MO

    Background/Purpose: Patients living with rheumatoid arthritis (RA) often also live with comorbid mental health conditions. Regardless of diagnosed mental health condition, living with a chronic…
  • Abstract Number: 0098 • ACR Convergence 2022

    Delays in Access to Specialized Care and Diagnosis in Patients with Systemic Lupus Erythematosus

    Alain Sanchez-Rodriguez1, Jose A Meade-Aguilar2, Jeffrey X. Yang2, Gabriel Figueroa Parra2, Shirley-Ann Osei-Onomah2, Rachel Giblon3, Hannah Langenfeld4, Alanna Chamberlain2, Cynthia Crowson5 and Ali Duarte-Garcia2, 1Division of Rheumatology, Mayo Clinic, Rochester, MN, 2Mayo Clinic, Rochester, MN, 3Mayo Clinic, Rochester, MN, Rochester, MN, 4Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, 5Mayo Clinic, Eyota, MN

    Background/Purpose: Delays in access to specialized care and diagnosis of systemic lupus erythematosus (SLE) are associated with poor outcomes. Prior studies rely mostly on cross-sectional…
  • Abstract Number: 0071 • ACR Convergence 2021

    Damage Accrual Measured by DIAPS in Antiphospholipid Antibody (aPL)-positive Patients: Results from AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) Clinical Database and Repository (“Registry”)

    Gustavo Balbi1, Yasaman Ahmadzadeh2, Maria Tektonidou3, Vittorio Pengo4, Savino Sciascia5, Amaia Ugarte6, H. Michael Belmont7, Maria Gerosa8, Paul R Fortin9, Chary lopez-pedrera10, Lanlan Ji11, Tatsuya Atsumi12, Hannah Cohen13, Guilherme Ramires de Jesus14, D. Ware Branch15, Cecilia Nalli16, Nina Kello17, Michelle Petri18, Esther Rodriguez-Almaraz19, Giuseppe Barilaro20, Jason Knight21, Bahar Artim-Esen22, Rohan Willis23, Maria Laura Bertolaccini24, Robert Roubey25, Doruk Erkan2, Danieli De Andrade1 and on Behalf of APS ACTION2, 1University of São Paulo, São Paulo, Brazil, 2Hospital for Special Surgery, New York, NY, 3FORZAFORTE HELLAS LTD, Athens, Greece, 4Padova University Hospital, Padova, Italy, 5University of Turin, Turin, Italy, 6Hospital Universitario Cruces, Barakaldo, Spain, 7NYU School of Medicine, New York, NY, 8University of Milan, Milan, Italy, 9CHU de Quebec - Universite Laval, Québec City, QC, Canada, 10IMIBIC/Reina Sofia Hospital/University of Córdoba, Córdoba, Spain, 11Peking University First Hospital, Beijing, China (People's Republic), 12Hokkaido University, Sapporo, Japan, 13Department of Haematology, University College London Hospitals NHS Foundation Trust, London, United Kingdom, 14Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil, 15University of Utah, Salt Lake City, UT, 16ASST SPEDALI CIVILI DI BRESCIA, Brescia, Italy, 17Zucker School of Medicine at Hofstra/Northwell Health, Manhasset, NY, 18Johns Hopkins University School of Medicine, Baltimore, MD, 19Hospital Universitario 12 de Octubre, Madrid, Spain, 20Clínic Barcelona - Hospital Universitari, Barcelona, Spain, 21University of Michigan, Ann Arbor, MI, 22Istanbul University School of Medicine, İstanbul, Turkey, 23University of Texas Medical Branch, Galveston, TX, 24King's College London, London, United Kingdom, 25University of North Carolina, Chapel Hill, NC

    Background/Purpose: Damage Index in APS (DIAPS) is a scoring system developed to assess long-term damage in thrombotic primary antiphospholipid syndrome (PAPS), which also correlates with…
  • Abstract Number: 0080 • ACR Convergence 2021

    One Point Increase in the Initial Damage as Measured by the Damage Index for Antiphospholipid Syndrome Predicts Mortality in a Multi-Ethnic Group of Thrombotic Antiphospholipid Syndrome Patients

    Pedro Gaspar1, Filipa Farinha2, Zara Sayar3, Maria Efthymiou,4, Hannah Cohen3 and David Isenberg2, 1Department of Internal Medicine 2, University Hospital of Santa Maria, Lisbon, Portugal, 2Centre for Rheumatology, University College London, London, United Kingdom, 3Department of Haematology, University College London Hospitals NHS Foundation Trust, London, United Kingdom, 4Haemostasis Research Unit, Department of Haematology, University College London, London, United Kingdom

    Background/Purpose: The chronic and recurrent nature of antiphospholipid syndrome (APS) leads to damage accrual that impairs long-term functional status and survival. The Damage Index for…
  • Abstract Number: 0388 • ACR Convergence 2021

    Prediction Tool for Damage Accrual Trajectory in Incident Systemic Sclerosis

    Ariane Barbacki1, Ada Man2, Mianbo Wang3, Dylan Johnson4, Yuqing Zhang5, Mandana Nikpour6 and Murray Baron7, 1McGill University, Montral, Montréal, QC, Canada, 2University of Manitoba, Winnipeg, MB, Canada, 3Lady Davis institute for Medical Research, Montréal, QC, Canada, 4University of Alberta, Edmonton, AB, Canada, 5Massachusetts General Hospital, Quincy, MA, 6University of Melbourne at St Vincent's Hospital, Melbourne, Australia, 7Jewish General Hospital, Montréal, QC, Canada

    Background/Purpose: Systemic sclerosis (SSc) is a systemic autoimmune disease associated with the accrual of organ damage over time, which can be measured using the Scleroderma…
  • Abstract Number: 0878 • ACR Convergence 2021

    Investigating the Neutrophil to Lymphocyte Ratio as a Marker of SLE Disease Activity, Health-Related Quality of Life and Depression

    Eleni Papachristodoulou1, Loukas Kakoullis1, Savvas Psarelis2, Victor Hajiroussos3, Costas Christophi4 and Konstantinos Parperis1, 1University of Cyprus Medical School, Nicosia, Cyprus, 2Nicosia General Hospital/University of Cyprus Medical Schooll, Nicosia, Cyprus, 3Ygia Polyclinic Hospital, Limassol, Cyprus, 4Cyprus University of Technology, Limassol, Cyprus

    Background/Purpose: The need for readily available markers of SLE activity has led to the evaluation of laboratory parameters, such as the neutrophil to lymphocyte ratio…
  • Abstract Number: 0267 • ACR Convergence 2020

    Gastrointestinal Disease in SLE: Does It Indicate a Worse Prognosis?

    Beatriz Tejera Segura1, Irene Altabás González2, Iñigo Rúa-Figueroa3, Natalia Pérez Veiga4, Victor del Campo Pérez5, Alejandro Olivé-Marqués6, Maria Galindo-Izquierdo7, Jaime Calvo-Alén8, Juan Ovalles-Bonilla9, Antonio Fernandez-Nebro10, Raul Menor Almagro11, Eva Tomero Muriel12, N. Del-val-del-amo13, Maria Esther Uriarte14, VM Martínez Taboada15, Jose Luis Andreu Sanchez16, Alina Lucica Boteanu17, Francisco Javier Narváez18, A Morasat19, Carlos Montilla Morales20, JM Senabre Gallego21, Blanca Hernández Cruz22, Mariano Andrés23, Eva Salgado Pérez24, Mercedes Freire-González25, Sergio Ramon Machin Garcia1, Clara Moriano26, Lorena Expósito27, Clara E. Perez-Velasquez28, ML Velloso-Feijoo29, Ana Paula Cacheda30, Nuria Lozano Rivas31, Gema Bonilla32, Marta Arévalo33, Inmaculada Jimenez34, VE Quevedo-Vila35, Francisco Manero-Ruiz36, Paloma García de la Peña37, TR Vázquez-Rodríguez38, J Ibáñez-Ruan39, Tatiana Cobo-Ibañez40 and Jose Maria Pego-Reigosa41, 1Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, Spain, 2Complejo Hospitalario Universitario de Vigo, Vigo, Pontevedra, Spain, 3Hospital Universitario de Gran Canaria Dr Negrín, Las Palmas de Gran Canaria, Spain, 4Grupo IRIDIS, Universidad de Vigo, Vigo, Pontevedra, 5Hospital Universitario Meixoeiro, Vigo, Vigo, Pontevedra, Spain, 6Hospital Germans Trias i Pujol, Barcelona, Spain, 7Hospital Universitario 12 de Octubre, Madrid, Spain, 8Hospital Universitario Araba, Vitoria-Gasteiz, Pais Vasco, Spain, 9Hospital General Universitario Gregorio Marañón, Madrid, Spain, 10University of Malaga, Malaga, Spain, 11Hospital General Universitario de Jerez de la Frontera, Puerto De Santa Mar�a, Spain, 12Hospital Universitario de la Princesa, Madrid, Madrid, Spain, 13Complejo Hospitalario de Navarra, Pamplona, Spain, 14Hospital Universitario Donostia, San Sebastian, Spain, 15Hospital Universitario Marqués de Valdecilla, Santander, Spain, 16Hospital Universitario Puerta de Hierro, Majadahonda, Spain, 17PRINTO, Istituto Giannina Gaslini, Genova, Italy, 18Hospital Bellvitge, BARCELONA, Spain, 19Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Spain, 20Hospital Universitario de Salamanca, Salamanca, Spain, 21Hospital Marina Baixa, Alicante, Spain, 22Universidad de Sevilla, Sevilla, Spain, 23Hospital General Universitario de Alicante, Alicante, Spain, 24Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, Spain, 25CHU Coruña, Coruña, Spain, 26Complejo Asistencial Universitario de León, León, Spain, 27Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, 28Basurto University Hospital, Bilbao, Spain, 29Hospital Universitario de Valme, Sevilla, Spain, 30Hospital son LLátzer, Palma de Mallorca, Spain, 31Hospital Clínico Universitario Virgen de Arrixaca, Murcia, Spain, 32Rheumatology, La Paz University Hospital-IdiPAZ, Madrid, Spain, 33Hospital Universitari Parc Taulí I3PT, Sabadell, Spain, 34Hospital Clínico San Ceciio Granada, Granada, Spain, 35Hospital Comarcal de Monforte, Lugo, Spain, 36Hospital Universitario Miguel Servet, Zaragoza, Spain, 37Hospital HM, Madrid, Spain, 38Hospital Universitario Lucus Augusti, Lugo, Spain, 39Hospital Povisa, Vigo, Pontevedra, Spain, 40Hospital Infanta Sofia, Madrid, Spain, 41University Hospital of Vigo, Galicia Sur Health Research Institute, Vigo, Spain

    Background/Purpose: To describe the GI manifestations of SLE in the RELESSER (Registry of Systemic Lupus Erythematosus Patients of the Spanish Society of Rheumatology) cohort and…
  • Abstract Number: 0271 • ACR Convergence 2020

    External Validation of the Systemic Lupus International Collaborating Clinics Frailty Index (SLICC-FI) as a Predictor of Mortality and Organ Damage Accrual in Systemic Lupus Erythematosus

    Alicia Malone1, Alexandra Legge1 and John Hanly1, 1Dalhousie University, Halifax, NS, Canada

    Background/Purpose: Using data from the Systemic Lupus International Collaborating Clinics (SLICC) inception cohort, a frailty index (FI) was recently developed as a measure of susceptibility…
  • Abstract Number: 0853 • ACR Convergence 2020

    Gradual Glucocorticoid Withdrawal Is Safe in Clinically Quiescent Systemic Lupus Erythematosus

    Konstantinos Tselios1, Dafna Gladman2, Jiandong Su3 and Murray Urowitz1, 1University Health Network, University of Toronto, Toronto, ON, Canada, 2Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada, 3University of Toronto Lupus Clinic, Centre for Prognosis Studies in Rheumatic Diseases, Toronto Western Hospital, University Health Network, Toronto, ON, Canada

    Background/Purpose: Systemic lupus erythematosus (SLE) patients are usually treated with glucocorticoids even during periods of clinically quiescent disease. A recent study showed that abrupt glucocorticoid…
  • Abstract Number: 0864 • ACR Convergence 2020

    Effect of Cumulative Hydroxychloroquine Dose on Prevention of Damage Progression in Patients with Systemic Lupus Erythematosus

    Lisa Zhu1, Manpreet Singh2, Caroline Siegel3, Lori Sahakian2, Jennifer Grossman4 and Maureen McMahon5, 1University of California, Los Angeles, Van Nuys, CA, 2University of California, Los Angeles, Los Angeles, CA, 3Hospital for Special Surgery, New York, NY, 4University of California, Los Angeles, Sherman Oaks, CA, 5University of California Los Angeles, Los Angeles, CA

    Background/Purpose: Hydroxychloroquine (HCQ) has demonstrated a wide array of beneficial effects in patients with systemic lupus erythematosus (SLE), with regard to disease activity, flare rates,…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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