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Abstracts tagged "Damage Index"

  • Abstract Number: 0343 • ACR Convergence 2022

    Severe Non-adherence to Hydroxychloroquine Is Associated with Flares, Early Damage, and Mortality in Systemic Lupus Erythematosus: Data from 660 Patients from the Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort

    Yann Nguyen1, Benoît BLanchet2, Murray Urowitz3, John Hanly4, Caroline Gordon5, Sang-Cheol Bae6, Juanita Romero-Diaz7, Jorge Sanchez-Guerrero8, Ann E Clarke9, Sasha Bernatsky10, Daniel Wallace11, David Isenberg12, Anisur Rahman13, Joan Merrill14, Paul R Fortin15, Dafna Gladman16, Ian N. Bruce17, Michelle Petri18, Ellen M. Ginzler19, Mary Anne Dooley20, Rosalind Ramsey-Goldman21, Susan Manzi22, Andreas Jönsen23, Graciela Alarcón24, Ronald van Vollenhoven25, Cynthia Aranow26, Veronique Le Guern27, Meggan Mackay26, Guillermo Ruiz-Irastorza28, S. Sam Lim29, Murat Inanc30, Kenneth C Kalunian31, Soren Jacobsen32, Christine Peschken33, Diane Kamen34, Anca Askanase35, Jill Buyon36 and Nathalie Costedoat-Chalumeau37, 1AP-HP.Centre Universit Paris Cit Hôpital Cochin, Montmorency, France, 2Biologie du médicament-Toxicologie, AP-HP Centre – Hôpital Cochin, Université Paris Cité, Paris, France, Paris, 3University of Toronto, University Health Network, Schroeder Arthritis Institute, Toronto, ON, Canada, 4Division of Rheumatology, Queen Elizabeth II Health Sciences Center (Nova Scotia Rehabilitation Site) and Dalhousie University, Halifax, NS, Canada, 5Rheumatology Research Group, Institute of Inflammation and Ageing, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom, 6Hanyang University Medical Center, Seoul, Republic of Korea, 7Instituto Nacional de Ciencias Medicas y Nutricion SZ, Ciudad de México, Mexico, 8Mount Sinai Hospital and University Health Network, University of Toronto, Toronto, ON, Canada, 9University of Calgary, Division of Rheumatology, Cumming School of Medicine, Calgary, AB, Canada, 10Research Institute of the McGill University Health Centre, Montréal, QC, Canada, 11Cedars-Sinai Medical Center, Los Angeles, CA, 12University College London, London, United Kingdom, 13Centre for Rheumatology, Department of Medicine, University College London, London, United Kingdom, 14Oklahoma Medical Research Foundation, Oklahoma City, OK, 15Centre ARThrite - CHU de Québec - Université Laval, Québec, QC, Canada, 16Toronto Western Hospital, Schroeder Arthritis Institute, Toronto, ON, Canada, 17Centre for Epidemiology Versus Arthritis, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom, 18Johns Hopkins University School of Medicine, Division of Rheumatology, Baltimore, MD, 19SUNY Downstate Health Sciences University, Department of Medicine, Brooklyn, NY, 20Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, 21Northwestern University Feinberg School of Medicine, Chicago, USA, Chicago, IL, 22Allegheny Health Network, Lupus Center of Excellence, Wexford, PA, 23Lund University, Lund, Sweden, 24The University of Alabama at Birmingham, Oakland, 25Amsterdam University Medical Centers, Amsterdam, Netherlands, 26Feinstein Institutes for Medical Research, Manhasset, NY, 27Hôpital Cochin, Paris, France, 28Autoimmune Diseases Research Unit, Biocruces Bizkaia Health Research Institute, Hospital Universitario Cruces, UPV/EHU, Barakaldo, Spain, 29Emory University, Atlanta, GA, 30Division of Rheumatology, Department of Internal Medicine, Istanbul Medical Faculty, Istanbul University, Istambul, Turkey, 31University of California San Diego School of Medicine, La Jolla, 32Rigshospitalet, Copenhagen, Denmark, 33University of Manitoba, Winnipeg, MB, Canada, 34Medical University of South Carolina, Charleston, SC, 35Columbia University Medical Center, New York, NY, 36NYU Grossman School of Medicine, New York, NY, 37Inserm DR Paris 5, Paris, France

    Background/Purpose: The efficacy of antimalarials, especially hydroxychloroquine (HCQ), in preventing flares of systemic lupus erythematosus (SLE) is well demonstrated, but its effectiveness is impaired by…
  • Abstract Number: 0541 • ACR Convergence 2022

    Prevalence of Venous Thrombo-Embolism in Lupus Nephritis and Associated Risk Factors

    Tara Tofighi, Jiandong Su and Zahi Touma, Schroeder Arthritis Institute, Krembil Research Institute, University Health Network and University of Toronto, Toronto, ON, Canada

    Background/Purpose: Patients with SLE have an increased risk of developing venous thrombo-embolism (VTE) based on several cohort studies, accounting for significant morbidity and mortality. Lupus…
  • Abstract Number: 0677 • ACR Convergence 2022

    Obstructive Sleep Apnea in Primary Antiphospholipid Syndrome Impacts Damage Accrual

    Gustavo Balbi1, Flavio Victor Signorelli2, Ana Paula Gandara3, Indira Azam3, Dilson Marreiros3, Luciano Drager3 and Danieli Castro Oliveira de Andrade4, 1Universidade de São Paulo, São Paulo, Brazil, 2Universidade do Estado do Rio de Janeiro, Rio De Janeiro, Brazil, 3University of São Paulo, São Paulo, Brazil, 4Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Obstructive sleep apnea (OSA) has been associated with an increased risk of thrombotic-related events, such as myocardial infarction and cerebrovascular diseases in the general…
  • Abstract Number: 0982 • ACR Convergence 2022

    Effect of Cumulative Hydroxychloroquine Dose on Prevention of Damage Progression and Cardiovascular Events in Patients with Systemic Lupus Erythematosus

    Jordan Jacquez1, Lisa Zhu1, Manpreet Singh1, Caroline Siegel2, Lori Sahakian1, Brian Skaggs1, Jennifer Grossman1 and Maureen McMahon1, 1University of California Los Angeles, Los Angeles, CA, 2Hospital for Special Surgery, New York, NY

    Background/Purpose: Hydroxychloroquine (HCQ) has demonstrated benefit in multiple outcomes in systemic lupus erythematosus (SLE), including disease activity, flare rates, survival, and thrombotic events. Previous studies,…
  • Abstract Number: 1528 • ACR Convergence 2022

    Nintedanib in Patients with Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD) and Organ Damage: Data from the SENSCIS Trial

    Janet Pope1, Susanna Proudman2, Wendy Stevens3, Joerg Henes4, Rozeta Simonovska5, Margarida Alves6 and Yannick Allanore7, 1University of Western Ontario, London, ON, Canada, 2Rheumatology Unit, Royal Adelaide Hospital, and Discipline of Medicine, University of Adelaide, Adelaide, Australia, 3Department of Rheumatology, St Vincent’s Hospital, Melbourne, Australia, Melbourne, Australia, 4Center for Interdisciplinary Clinical Immunology, Rheumatology and Auto-inflammatory Diseases (INDIRA), University Hospital Tübingen, Tübingen, Germany, 5mainanalytics GmbH, Sulzbach (Taunus), Germany, Sulzbach (Taunus), Germany, 6Boehringer Ingelheim International GmbH, Ingelheim am Rhein, Germany, 7Department of Rheumatology A, Descartes University, APHP, Cochin Hospital, Paris, France, Paris, France

    Background/Purpose: The Scleroderma Clinical Trials Consortium Damage Index (SCTC-DI) was developed to quantify organ damage in patients with SSc. We assessed outcomes in the SENSCIS…
  • Abstract Number: 1562 • ACR Convergence 2022

    Validation of Behçet’s Disease Overall Damage Index (BODI) for Retrospective Studies and a Proposal for Modification

    Yeliz Yagiz Ozogul1, Yesim Ozguler2, Didar Ucar3, Ugur Uygunoglu4, Zekayi Kutlubay5, Vedat Hamuryudan6 and gulen Hatemi7, 1Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School, Department of Internal Medicine, Istanbul, Turkey, 2Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, New York, NY, 3Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School, Department of Ophthalmology, Istanbul, Turkey, 4Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School, Department of Neurology, Istanbul, Turkey, 5Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School, Department of Dermatology, Istanbul, Turkey, 6Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 7Istanbul University-Cerrahpaşa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey

    Background/Purpose: Damage accrual in Behçet syndrome (BS) may progress over the years and an index that can be scored using retrospective data may be useful…
  • Abstract Number: 1602 • ACR Convergence 2022

    Fibroblast Activation Protein (FAP) PET-CT for Depicting Inflammatory Joint Damage in Patients with Psoriatic Arthritis

    Simon Rauber1, Hashem Mohammadian2, Chrstian Schmidkonz3, Armin Atzinger3, Maria Gabriella Raimondo1, Hannah Labinsky4, Christoph Treutlein2, Johannes Knitza1, Simone Maschauer2, Frank Roemer5, Olaf Prante2, Torsten Kuwert3, Juan Canete6, Georg Schett7 and Andreas Ramming1, 1Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-UniversityErlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, 2Friedrich-Alexander-University (FAU) Erlangen-Nürnberg, Erlangen, Germany, 3Friedrich-Alexander University (FAU) Erlangen-Nuremberg, Erlangen, Germany, 4Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, 5Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany, 6Unidad de Artritis Hospital Clinic, Barcelona, Spain, 7Universitätsklinikum Erlangen, Erlangen, Germany

    Background/Purpose: Psoriatic arthritis (PsA) is characterized by substantial mesenchymal tissue activation in the context of inflammation leading to structural damage. Measuring mesenchymal tissue activation in…
  • Abstract Number: 0071 • ACR Convergence 2021

    Damage Accrual Measured by DIAPS in Antiphospholipid Antibody (aPL)-positive Patients: Results from AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) Clinical Database and Repository (“Registry”)

    Gustavo Balbi1, Yasaman Ahmadzadeh2, Maria Tektonidou3, Vittorio Pengo4, Savino Sciascia5, Amaia Ugarte6, H. Michael Belmont7, Maria Gerosa8, Paul R Fortin9, Chary lopez-pedrera10, Lanlan Ji11, Tatsuya Atsumi12, Hannah Cohen13, Guilherme Ramires de Jesus14, D. Ware Branch15, Cecilia Nalli16, Nina Kello17, Michelle Petri18, Esther Rodriguez-Almaraz19, Giuseppe Barilaro20, Jason Knight21, Bahar Artim-Esen22, Rohan Willis23, Maria Laura Bertolaccini24, Robert Roubey25, Doruk Erkan2, Danieli De Andrade1 and on Behalf of APS ACTION2, 1University of São Paulo, São Paulo, Brazil, 2Hospital for Special Surgery, New York, NY, 3FORZAFORTE HELLAS LTD, Athens, Greece, 4Padova University Hospital, Padova, Italy, 5University of Turin, Turin, Italy, 6Hospital Universitario Cruces, Barakaldo, Spain, 7NYU School of Medicine, New York, NY, 8University of Milan, Milan, Italy, 9CHU de Quebec - Universite Laval, Québec City, QC, Canada, 10IMIBIC/Reina Sofia Hospital/University of Córdoba, Córdoba, Spain, 11Peking University First Hospital, Beijing, China (People's Republic), 12Hokkaido University, Sapporo, Japan, 13Department of Haematology, University College London Hospitals NHS Foundation Trust, London, United Kingdom, 14Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil, 15University of Utah, Salt Lake City, UT, 16ASST SPEDALI CIVILI DI BRESCIA, Brescia, Italy, 17Zucker School of Medicine at Hofstra/Northwell Health, Manhasset, NY, 18Johns Hopkins University School of Medicine, Baltimore, MD, 19Hospital Universitario 12 de Octubre, Madrid, Spain, 20Clínic Barcelona - Hospital Universitari, Barcelona, Spain, 21University of Michigan, Ann Arbor, MI, 22Istanbul University School of Medicine, İstanbul, Turkey, 23University of Texas Medical Branch, Galveston, TX, 24King's College London, London, United Kingdom, 25University of North Carolina, Chapel Hill, NC

    Background/Purpose: Damage Index in APS (DIAPS) is a scoring system developed to assess long-term damage in thrombotic primary antiphospholipid syndrome (PAPS), which also correlates with…
  • Abstract Number: 0080 • ACR Convergence 2021

    One Point Increase in the Initial Damage as Measured by the Damage Index for Antiphospholipid Syndrome Predicts Mortality in a Multi-Ethnic Group of Thrombotic Antiphospholipid Syndrome Patients

    Pedro Gaspar1, Filipa Farinha2, Zara Sayar3, Maria Efthymiou,4, Hannah Cohen3 and David Isenberg2, 1Department of Internal Medicine 2, University Hospital of Santa Maria, Lisbon, Portugal, 2Centre for Rheumatology, University College London, London, United Kingdom, 3Department of Haematology, University College London Hospitals NHS Foundation Trust, London, United Kingdom, 4Haemostasis Research Unit, Department of Haematology, University College London, London, United Kingdom

    Background/Purpose: The chronic and recurrent nature of antiphospholipid syndrome (APS) leads to damage accrual that impairs long-term functional status and survival. The Damage Index for…
  • Abstract Number: 0388 • ACR Convergence 2021

    Prediction Tool for Damage Accrual Trajectory in Incident Systemic Sclerosis

    Ariane Barbacki1, Ada Man2, Mianbo Wang3, Dylan Johnson4, Yuqing Zhang5, Mandana Nikpour6 and Murray Baron7, 1McGill University, Montral, Montréal, QC, Canada, 2University of Manitoba, Winnipeg, MB, Canada, 3Lady Davis institute for Medical Research, Montréal, QC, Canada, 4University of Alberta, Edmonton, AB, Canada, 5Massachusetts General Hospital, Quincy, MA, 6University of Melbourne at St Vincent's Hospital, Melbourne, Australia, 7Jewish General Hospital, Montréal, QC, Canada

    Background/Purpose: Systemic sclerosis (SSc) is a systemic autoimmune disease associated with the accrual of organ damage over time, which can be measured using the Scleroderma…
  • Abstract Number: 0878 • ACR Convergence 2021

    Investigating the Neutrophil to Lymphocyte Ratio as a Marker of SLE Disease Activity, Health-Related Quality of Life and Depression

    Eleni Papachristodoulou1, Loukas Kakoullis1, Savvas Psarelis2, Victor Hajiroussos3, Costas Christophi4 and Konstantinos Parperis1, 1University of Cyprus Medical School, Nicosia, Cyprus, 2Nicosia General Hospital/University of Cyprus Medical Schooll, Nicosia, Cyprus, 3Ygia Polyclinic Hospital, Limassol, Cyprus, 4Cyprus University of Technology, Limassol, Cyprus

    Background/Purpose: The need for readily available markers of SLE activity has led to the evaluation of laboratory parameters, such as the neutrophil to lymphocyte ratio…
  • Abstract Number: 1298 • ACR Convergence 2020

    Lupus Damage Free-Survival by Age at Diagnosis: A Retrospective Incident Lupus Cohort

    Maria Schletzbaum1, Nnenna Ezeh2, Trevor McKown3, Shivani Garg4 and Christie Bartels5, 1University of Wisconsin-Madison School of Medicine and Public Health, Department of Population Health Sciences, Madison, WI, 2University of Wisconsin School of Medicine and Public Health, Milwaukee, WI, 3William S. Middleton Memorial Veterans Hospital, Madison, WI, 4UW Madison, Madison, WI, 5University of Wisconsin School of Medicine and Public Health, Department of Medicine, Division of Rheumatology, Madison, WI

    Background/Purpose: While medical comorbidities increase with age, younger age at onset of Systemic Lupus Erythematosus (SLE) has been associated with greater risk of some types…
  • Abstract Number: 1393 • ACR Convergence 2020

    Systemic Sclerosis: Subclinical Aterosclerosis and Morbimortality

    Miriam Retuerto1, Jose Luis Rosales2, Maria Martin1, Beatriz Joven1 and Patricia E Carreira1, 1Hospital universitario 12 de octubre, Madrid, Spain, 2Hospiten Rambla, Santa Cruz de Tenerife, Spain

    Background/Purpose: Rheumatic diseases are associated with accelerated atherosclerosis, and an increase in cardiovascular morbidity and mortality. This process is mediated by classic cardiovascular risk factors…
  • Abstract Number: 2036 • ACR Convergence 2020

    Damage Trajectories in Systemic Sclerosis Using Group-Based Trajectory Modeling

    Ariane Barbacki1, Murray Baron2, Mianbo Wang3, Yuqing Zhang4, Mandana Nikpour5 and Ada Man6, 1McGill University Health Center, Montreal, QC, Canada, 2Jewish General Hospital, Montreal, QC, Canada, 3Lady Davis institute for Medical Research, Montreal, QC, Canada, 4Massachusetts General Hospital, Harvard Medical School, Boston, 5The University of Melbourne at St. Vincent's Hospital, Melbourne, Victoria, Australia, 6University of Manitoba, Winnipeg, MB, Canada

    Background/Purpose: Systemic sclerosis (SSc) is a rare systemic autoimmune disease associated with a high mortality and characterized by the accrual of organ damage over time.…
  • Abstract Number: 0267 • ACR Convergence 2020

    Gastrointestinal Disease in SLE: Does It Indicate a Worse Prognosis?

    Beatriz Tejera Segura1, Irene Altabás González2, Iñigo Rúa-Figueroa3, Natalia Pérez Veiga4, Victor del Campo Pérez5, Alejandro Olivé-Marqués6, Maria Galindo-Izquierdo7, Jaime Calvo-Alén8, Juan Ovalles-Bonilla9, Antonio Fernandez-Nebro10, Raul Menor Almagro11, Eva Tomero Muriel12, N. Del-val-del-amo13, Maria Esther Uriarte14, VM Martínez Taboada15, Jose Luis Andreu Sanchez16, Alina Lucica Boteanu17, Francisco Javier Narváez18, A Morasat19, Carlos Montilla Morales20, JM Senabre Gallego21, Blanca Hernández Cruz22, Mariano Andrés23, Eva Salgado Pérez24, Mercedes Freire-González25, Sergio Ramon Machin Garcia1, Clara Moriano26, Lorena Expósito27, Clara E. Perez-Velasquez28, ML Velloso-Feijoo29, Ana Paula Cacheda30, Nuria Lozano Rivas31, Gema Bonilla32, Marta Arévalo33, Inmaculada Jimenez34, VE Quevedo-Vila35, Francisco Manero-Ruiz36, Paloma García de la Peña37, TR Vázquez-Rodríguez38, J Ibáñez-Ruan39, Tatiana Cobo-Ibañez40 and Jose Maria Pego-Reigosa41, 1Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, Spain, 2Complejo Hospitalario Universitario de Vigo, Vigo, Pontevedra, Spain, 3Hospital Universitario de Gran Canaria Dr Negrín, Las Palmas de Gran Canaria, Spain, 4Grupo IRIDIS, Universidad de Vigo, Vigo, Pontevedra, 5Hospital Universitario Meixoeiro, Vigo, Vigo, Pontevedra, Spain, 6Hospital Germans Trias i Pujol, Barcelona, Spain, 7Hospital Universitario 12 de Octubre, Madrid, Spain, 8Hospital Universitario Araba, Vitoria-Gasteiz, Pais Vasco, Spain, 9Hospital General Universitario Gregorio Marañón, Madrid, Spain, 10University of Malaga, Malaga, Spain, 11Hospital General Universitario de Jerez de la Frontera, Puerto De Santa Mar�a, Spain, 12Hospital Universitario de la Princesa, Madrid, Madrid, Spain, 13Complejo Hospitalario de Navarra, Pamplona, Spain, 14Hospital Universitario Donostia, San Sebastian, Spain, 15Hospital Universitario Marqués de Valdecilla, Santander, Spain, 16Hospital Universitario Puerta de Hierro, Majadahonda, Spain, 17PRINTO, Istituto Giannina Gaslini, Genova, Italy, 18Hospital Bellvitge, BARCELONA, Spain, 19Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Spain, 20Hospital Universitario de Salamanca, Salamanca, Spain, 21Hospital Marina Baixa, Alicante, Spain, 22Universidad de Sevilla, Sevilla, Spain, 23Hospital General Universitario de Alicante, Alicante, Spain, 24Complejo Hospitalario Universitario de Santiago de Compostela, Santiago de Compostela, Spain, 25CHU Coruña, Coruña, Spain, 26Complejo Asistencial Universitario de León, León, Spain, 27Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, 28Basurto University Hospital, Bilbao, Spain, 29Hospital Universitario de Valme, Sevilla, Spain, 30Hospital son LLátzer, Palma de Mallorca, Spain, 31Hospital Clínico Universitario Virgen de Arrixaca, Murcia, Spain, 32Rheumatology, La Paz University Hospital-IdiPAZ, Madrid, Spain, 33Hospital Universitari Parc Taulí I3PT, Sabadell, Spain, 34Hospital Clínico San Ceciio Granada, Granada, Spain, 35Hospital Comarcal de Monforte, Lugo, Spain, 36Hospital Universitario Miguel Servet, Zaragoza, Spain, 37Hospital HM, Madrid, Spain, 38Hospital Universitario Lucus Augusti, Lugo, Spain, 39Hospital Povisa, Vigo, Pontevedra, Spain, 40Hospital Infanta Sofia, Madrid, Spain, 41University Hospital of Vigo, Galicia Sur Health Research Institute, Vigo, Spain

    Background/Purpose: To describe the GI manifestations of SLE in the RELESSER (Registry of Systemic Lupus Erythematosus Patients of the Spanish Society of Rheumatology) cohort and…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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