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Abstracts tagged "Damage Index"

  • Abstract Number: 1451 • ACR Convergence 2023

    Evaluation of Changes in SLE Patients’ Phenotype at Disease Onset, and Assessment of Disease Activity, Damage and Therapy at Diagnosis and During Follow up in the Last Forty Years: Preliminary Data of a Single Center Experience

    Micaela Fredi1, Silvia Ebe Lucia Della Pina1, Claudia Barison1, Chiara Orlandi1, Marzia Tedeschi2, Mai Chiara2, Cecilia Nalli1 and Franco Franceschini1, 1Rheumatology and Clinical Immunology, ASST Spedali Civili of Brescia, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy, 2University of Brescia, Brescia, Italy

    Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease associated with a high degree of variability at onset, which may make SLE diagnosis challenging, with…
  • Abstract Number: 1452 • ACR Convergence 2023

    Inflammatory Markers and Left Ventricular Dysfunction in Systemic Lupus Erythematosus (SLE)

    Audrey Hagiwara, Moumita Bose, Marianne Bernardo, Michael Nelson, Mariko Ishimori, Daniel Berman, C. Noel Bairey Merz, janet wei and Caroline Jefferies, Cedars-Sinai Medical Center, Los Angeles, CA

    Background/Purpose: Women with SLE have an elevated risk of cardiovascular disease. Many women with SLE frequently report chest pain in the absence of obstructive coronary…
  • Abstract Number: 1459 • ACR Convergence 2023

    Unveiling the Impact of Neuropsychiatric Involvement in Systemic Lupus Erythematosus on Damage Accrual

    Dionysis Nikolopoulos1, Nursen Cetrez2, Julius Lindblom2 and Ioannis Parodis2, 1Karolinska Institutet and Karolinska University Hospital, Division of Rheumatology, Department of Medicine Solna, Stockholm, Sweden, 2Karolinska Institutet, Stockholm, Sweden

    Background/Purpose: The link between neuropsychiatric involvement in systemic lupus erythematosus (NPSLE) and heightened morbidity, mortality, and organ damage, as well as detrimental impacts on health-related…
  • Abstract Number: 1462 • ACR Convergence 2023

    Cardiovascular Damage in Systemic Lupus Erythematosus Occurs at Early Stages of the Disease. Chronological Analysis of Damage Accrual in a Large Cohort from the Spanish Society of Rheumatology Lupus Registry (RELESSER)

    Sara garcia Perez1, Jose-Maria Pego-Reigosa2, Irene Altabás González1, Norman Jiménez3, Victor Del campo Perez4, JULIA MARTINEZ BARRIO5, Maria Galindo-Izquierdo6, Jaime Calvo- Alén7, Esther Uriarte Isacelaya8, Eva Tomero Muriel9, Mercedes Freire González10, Victor Martinez-Taboada11, Paloma Vela12, Antonio Fernandez-Nebro13, Alejandro Olivé-Marqués14, Javier Narvaez15, Raúl Menor-Almagro16, Gregorio Santos Soler17, José Ángel Hernández Beriain18, Javier Manero ruiz19, Elena Aurrecoechea Aguinaga20, Oihane Ibarguengoitia-Barrena21, Carlos Montilla-Morales22, Gema Bonilla23, Vicente Torrente-Segarra24, Ana Paula Cacheda25, Maria J. García-Villanueva26, Clara Moriano Morales27, Concepción Fito Manteca28, Cristina Bohórquez29, Nuria Lozano Rivas30 and Iñigo Rúa-Figueroa31, 1Department of Rheumatology, University Hospital of Vigo. IRIDIS Group (Investigation in Rheumatology and Immune-Diseases), Vigo, Spain, 2Rheumatology, Hospital do Meixoeiro, Vigo, Spain, 3IIRIDIS (Investigation in Rheumatology and Immune-Mediated Diseases) Group, Galicia Sur Health Research Institute., Vigo, Spain, 4Department of Epidemiology, University Hospital of Vigo, IRIDIS Group (Investigation in Rheumatology and Immune-Diseases), Vigo, Spain, 5Rheumatology, Gregorio Marañon University Hospital, Madrid, Spain, 6Rheumatology, University Hospital of 12 de Octubre, Madrid, Spain, 7Rheumatology, Bioaraba Research Unit, Hospital Universitario Araba, Vitoria, Spain, 8Rheumatology, University Hospital of Donosti, San Sebastián, Spain, 9Rheumatology, Hospital La Princesa, Madrid, Spain, 10Rheumatology department, Complexo Hospitalario Universitario A Coruña (CHUAC). Instituto de Investigación Biomédica A Coruña (INIBIC), A Coruña, Spain, 11Rheumatology, Hospital Marqués de Valdecilla, Santander, Spain, 12Department of Rheumatology, University Hospital of Alicante, Alicante, Spain, 13Hospital Regional Universitario de Málaga, Malaga, Spain, 14Department of Rheumatology, Hospital Germans Trias i Pujol, Badalona, Spain, 15Hospital Universitario de Bellvitge, Barcelona, Spain, 16Rheumatology, Hospital Jerez, Puerto De Santa María, Spain, 17Rheumatology, Hospital Marina Baixa Villajoyosa, Alicante, Spain, 18Rheumatology, Hospital Insular de Gran Canaria, Las Palmas de Gran Canaria, Spain, 19Department of Rheumatology, Hospital Universitario Miguel Servet, Zaragoza, Spain, 20Department of Rheumatology, Hospital Sierrallana, Torrelavega, Spain, 21Galdakao-Usansolo University Hospital, Bilbao, Spain, 22Rheumatology, University Hospital of Salamanca, Salamanca, Spain, 23Department of Rheumatology, Hospital Clínico Universitario La Paz, Madrid, Spain, 24Department of Rheumatology, Hospital de Sant Joan Despí Moises Broggi,, Sant Joan Despí, Spain, 25Department of Rheumatology, Hospital Son Llatzer, Palma de Mallorca, Spain, 26Hospital Ramón y Cajal, Madrid, Spain, 27Rheumatology, Hospital Universitario de León, León, Spain, 28Department of Rheumatology, University Hospital of Navarra, Pamplona, Spain, 29Department of Rheumatology, University Hospital Príncipe de Asturias, Alcalá de Henares, Spain, 30Department of Rheumatology, Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain, 31Rheumatology, Hospital de Gran Canaria Doctor Negrin, Las Palmas de Gran Canaria, Spain

    Background/Purpose: Systemic Lupus Erythematosus (SLE) survival has improved during recent decades, so other outcomes like damage accrual become more relevant. Damage represents that clinical feature…
  • Abstract Number: 1567 • ACR Convergence 2023

    Assessment of the Extent and Accrual of Damage in Takayasu’s Arteritis

    Tanaz Kermani1, SEMA KAYMAZ-TAHRA2, David Cuthbertson3, Nader Khalidi4, Curry Koening5, Carol Langford6, Carol McAlear7, Paul Monach8, Larry Moreland9, Christian Pagnoux10, Philip Seo11, Antoine G Sreih12, Kenneth Warrington13, fatma Alibaz-Öner14, Haner Direskeneli15 and Peter Merkel7, 1Rheumatology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 2Sancaktepe Prof Dr Ilhan Varank Training and Research Hospital, Istanbul, Turkey, 3University of South Florida, Tampa, FL, 4McMaster University, Hamilton, ON, Canada, 5University of Texas Dell Medical School, Austin, TX, 6Cleveland Clinic, Cleveland, OH, 7University of Pennsylvania, Philadelphia, PA, 8VA Boston Healthcare System, Boston, MA, 9University of Colorado, Denver, CO, 10Mount Sinai Hospital, Toronto, ON, Canada, 11Johns Hopkins University, Baltimore, MD, 12Bristol Myers Squibb, Princeton Pike, NJ, 13Mayo Clinic, Rochester, MN, 14Marmara University, School of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 15Division of Rheumatology, Medical School, Marmara University, Istanbul, Turkey

    Background/Purpose: Damage is the irreversible consequence of disease or its treatment. This study aimed to evaluate the accrual of damage in Takayasu's arteritis (TAK) using…
  • Abstract Number: 2265 • ACR Convergence 2023

    Lupus Damage Index Revision – Item Generation and Reduction Phase

    Burak Kundakci1, Megan Barber2, Ann Clarke2, Sindhu Johnson3, Ian Bruce4 and On behalf of the revised SLE organ damage index (SDI) collaborators4, 1Centre for Epidemiology Versus Arthritis, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom, 2University of Calgary, Division of Rheumatology, Cumming School of Medicine, Calgary, AB, Canada, 3Division of Rheumatology, Department of Medicine, Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western and Mount Sinai Hospitals; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada, 4University of Manchester, Manchester, United Kingdom

    Background/Purpose: The SDI is a robust instrument, but is limited by incomplete items, restricted applicability in paediatric patients, and outdated item definitions1. The SLICC, ACR…
  • Abstract Number: 2280 • ACR Convergence 2023

    The LFA-REAL Clinician Reported Outcome Predicts Damage in Patients with Systemic Lupus Erythematosus (SLE). Data from a Prevalent Latin American Lupus Cohort

    Manuel Ugarte-Gil1, Rocío Gamboa-Cárdenas2, Victor Pimentel-Quiroz2, Cristina Reategui-Sokolova3, Claudia Elera-Fitzcarrald4, Erika Noriega5, Cesar Pastor-Asurza6, Zoila Rodriguez-Bellido6, Risto Perich-Campos6 and Graciela S Alarcón7, 1Universidad Cientifica del Sur, Lima, Peru, 2Universidad Cientifica del Sur/Hospital Guillermo Almenara Irigoyen, EsSalud, Lima, Peru, 3Hospital Guillermo Almenara Irigoyen, EsSalud/Universidad San Ignacio de Loyola, Lima, Peru, 4Hospital Guillermo Almenara Irigoyen, EsSalud/Universidad Privada San Juan Bautista, Lima, Peru, 5Hospital Guillermo Almenara Irigoyen, EsSalud, Lima, Peru, 6Hospital Guillermo Almenara Irigoyen, EsSalud/Universidad Nacional Mayor de San Marcos, Lima, Peru, 7Heersink School of Medicine. The University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: The Lupus Foundation of America Rapid Evaluation of Activity in Lupus (LFA-REAL) clinican-reported outcome (ClinRO) correlates well with other disease activity indices such us…
  • Abstract Number: 2346 • ACR Convergence 2023

    SLE Medication Usage and Organ Damage Among Adult SLE Patients with SLE Treated with Belimumab (BEL): Pooled Data from Three Open-Label Extension Studies over 11+ Years

    Zahi Touma1, Cristina Arriens2, Christine Henning3, Angela Carroll3, Paula Curtis4, Roger A. Levy5 and William Stohl6, 1University of Toronto, Toronto, ON, Canada, 2Oklahoma Medical Research Foundation and University of Oklahoma Health Sciences Center, Department of Arthritis & Clinical Immunology, Oklahoma City, OK, 3GlaxoSmithKline, US Medical Affairs, Durham, NC, 4GlaxoSmithKline, R&D Biostatistics, Brentford, United Kingdom, 5GlaxoSmithKline, Global Medical Affairs, Collegeville, PA, 6University of Southern California Keck School of Medicine, Division of Rheumatology, Los Angeles, CA

    Background/Purpose: A key treatment goal for patients (pts) with SLE is to reduce use of CS, due to their association with organ damage.1 BEL is…
  • Abstract Number: 1877 • ACR Convergence 2022

    Nailfold Videocapillaroscopic Abnormalities Correlate with Disease Activity Measures and Cutaneous Damage in Patients with Idiopathic Inflammatory Myopathies

    Diane Zisa1, Aliza Bloostein1, Deanna Jannat-Khah, DrPH, MSPH1, Maurizio Cutolo2, Vanessa Smith3 and David Fernandez1, 1Hospital for Special Surgery, New York, NY, 2Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS San Martino Polyclinic Hospital, Genova, Italy, 3Department of Rheumatology, Ghent University Hospital – Department of Internal Medicine, Ghent University, Belgium – Unit for Molecular Immunology and Inflammation, VIB Inflammation Research Center (IRC), Gent, Belgium

    Background/Purpose: Nailfold videocapillaroscopy (NVC) is a non-invasive tool used to evaluate the microcirculation of patients with connective tissue diseases (CTDs). A specific combination of NVC…
  • Abstract Number: 2067 • ACR Convergence 2022

    Predictors of Organ Damage Accrual by Domains

    Rangi Kandane-Rathnayake1, Ning Li1, Vera Golder1, Worawit Louthrenoo2, Yi-Hsin Chen3, Jiacai Cho4, Aisha Lateef5, Laniyati Hamijoyo6, Luo Shue Fen7, Yeong-Jian Wu7, Sandra Navarra8, Leonid Zamora9, Zhanguo Li10, An Yuan11, Sargunan Sockalingam12, Yasuhiro Katsumata13, Masayoshi Harigai13, Yanjie Hao14, Zhouli Zhang15, Madelynn Chan16, Jun Kikuchi17, Tsutomu Takeuchi18, Shereen Oon19, Sang-Cheol Bae20, Fiona Goldblatt21, Sean O'Neill22, Kathy Gibson22, Kristine Ng23, Hui Nee Annie Law24, Duminda Basnayake25, Nicole Tugnet26, Sunil Kumar27, Cherica Tee28, Michael Tee28, Yoshiya Tanaka29, Chak Sing30, Mandana Nikpour31, Alberta Hoi32 and Eric Morand33, 1Monash University, Clayton, Australia, 2Chiang Mai University, Chiang Mai, Thailand, 3Taichung Veterans General Hospital, Taichung, Taiwan, 4National University Health System (NUHS), Singapore, Singapore, 5National University Hospital, Singapore, Singapore, 6Hasan Sadikin Hospital, Jakarta Selatan, Indonesia, 7Chang Gung Memorial Hospital, Taoyuan, Taiwan, 8University of Santo Tomas, Manila, Philippines, 9University of Santo Tomas Hospital, Manila, Philippines, 10People's Hospital, Peking University Health Science Center, Beijing, China, 11Peking University Health Science Center, Beijing, China, 12University of Malaya, Kuala Lumpur, Malaysia, 13Division of Rheumatology, Department of Internal Medicine, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan, 14The University of Melbourne, Melbourne, Australia, 15Peking University First Hospital, Beijing, China, 16Tan Tock Seng Hospital, Singapore, Singapore, 17Keio University, Tokyo, Japan, 18Keio University and Saitama Medical University, Tokyo, Japan, 19St Vincent's Hospital, Fitzroy, Australia, 20Hanyang University Medical Center, Seoul, Republic of Korea, 21Flinders Medical Centre, Adelaide, Australia, 22Liverpool Hospital, Sydney, Australia, 23North Shore Hospital, Auckland, New Zealand, 24Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore, 25Teaching Hospital Kandy, Kandy, Sri Lanka, 26Greenlane Clinical Centre, Auckland, New Zealand, 27Middlemore Hospital, Auckland, New Zealand, 28University of the Philippines, Quezon City, Philippines, 29University of Occupational and Environmental Health, Kitakyusyu Fukuoka, Japan, 30The University of Hong Kong, Pok Fu Lam, Hong Kong, 31The University of Melbourne at St. Vincent's Hospital Melbourne, Melbourne, Australia, 32Monash Health, Melbourne, Australia, 33Monash University, Victoria; Department of Rheumatology, Monash Health, Melbourne, Australia

    Background/Purpose: Prevention of organ damage is one of the main treatment goals in systemic lupus erythematosus (SLE).The SLICC/ACR Damage Index (SDI) is used to quantify…
  • Abstract Number: 2071 • ACR Convergence 2022

    The Systemic Lupus Erythematosus International Collaborating Clinics (SLICC), American College of Rheumatology (ACR), and Lupus Foundation of America (LFA) Damage Index Revision – Item Generation Phase

    Burak Kundakci1, Megan R W Barber2, Ann E Clarke2, Sindhu R. Johnson3, Hermine Brunner4, Jiacai Cho5, Nathalie Costedoat-Chalumeau6, Ellen M. Ginzler7, John Hanly8, Abida Hasan7, Murat İnanç9, Naureen Kabani7, Alexandra Legge10, Kaitlin Lima11, Livia Lindoso12, Anselm Mak13, Rosalind Ramsey-Goldman11, Guillermo Ruiz-Irastorza14, Clovis A. Silva12, Farah Tamirou15, Vitor C. Trindade12, Evelyne Vinet16 and Ian N. Bruce1, 1Centre for Epidemiology Versus Arthritis, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, United Kingdom, 2University of Calgary, Division of Rheumatology, Cumming School of Medicine, Calgary, AB, Canada, 3Division of Rheumatology, Department of Medicine, Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western and Mount Sinai Hospitals; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada, 4Division of Rheumatology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Department of Pediatrics, Cincinnati, OH, 5National University Health System (NUHS), Singapore, Singapore, 6Inserm DR Paris 5, Paris, France, 7SUNY Downstate Health Sciences University, Department of Medicine, Brooklyn, NY, 8Division of Rheumatology, Queen Elizabeth II Health Sciences Center (Nova Scotia Rehabilitation Site) and Dalhousie University, Halifax, NS, Canada, 9Istanbul University Faculty of Medicine, Istanbul, Turkey, 10Arthritis Research Canada, Dalhousie University, Halifax, NS, Canada, 11Northwestern University Feinberg School of Medicine, Chicago, USA, Chicago, IL, 12Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, Brazil, 13Division of Rheumatology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, 14Autoimmune Diseases Research Unit, Biocruces Bizkaia Health Research Institute, Hospital Universitario Cruces, UPV/EHU, Barakaldo, Spain, 15Rheumatology department, Cliniques Universitaires Saint-Luc, Brussels, Belgium, 16McGill University Health Centre, Montréal, QC, Canada

    Background/Purpose: The SLICC, ACR and LFA embarked on a data- and expert-driven project to develop a revised systemic lupus erythematosus (SLE) organ damage index (SDI).…
  • Abstract Number: 2089 • ACR Convergence 2022

    The Implication of Skin Involvement on Health-Related Quality of Life (HRQoL) in Systemic Lupus Erythematosus (SLE) Patients

    Alicia Van1, Vibeke Strand2, Jiandong Su1, Nicole Anderson1, Cheryl F Rosen3, Sherief Marzouk4, Lee S Simon5 and Zahi Touma1, 1Schroeder Arthritis Institute, Krembil Research Institute, University Health Network and University of Toronto, Toronto, ON, Canada, 2Stanford University School of Medicine, Stanford, CA, 3University of Toronto, Toronto, ON, Canada, 4University Health Network, University of Toronto, Toronto, ON, Canada, 5SDG LLC, West Newton, MA

    Background/Purpose: Skin involvement in Systemic Lupus Erythematosus (SLE) occurs in 50-85% of patients making it one of the most commonly affected organs in SLE. Previous…
  • Abstract Number: PP17 • ACR Convergence 2022

    Engaging with the Spoon Theory: How I Make Decisions Using a Cost-Benefit Analysis That Works to Improve My Mental Health While Living with RA

    Stephanie Aleite, AiArthritis, St. Louis, MO

    Background/Purpose: Patients living with rheumatoid arthritis (RA) often also live with comorbid mental health conditions. Regardless of diagnosed mental health condition, living with a chronic…
  • Abstract Number: 0098 • ACR Convergence 2022

    Delays in Access to Specialized Care and Diagnosis in Patients with Systemic Lupus Erythematosus

    Alain Sanchez-Rodriguez1, Jose A Meade-Aguilar2, Jeffrey X. Yang2, Gabriel Figueroa Parra2, Shirley-Ann Osei-Onomah2, Rachel Giblon3, Hannah Langenfeld4, Alanna Chamberlain2, Cynthia Crowson5 and Ali Duarte-Garcia2, 1Division of Rheumatology, Mayo Clinic, Rochester, MN, 2Mayo Clinic, Rochester, MN, 3Mayo Clinic, Rochester, MN, Rochester, MN, 4Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, 5Mayo Clinic, Eyota, MN

    Background/Purpose: Delays in access to specialized care and diagnosis of systemic lupus erythematosus (SLE) are associated with poor outcomes. Prior studies rely mostly on cross-sectional…
  • Abstract Number: 0160 • ACR Convergence 2022

    Sarcopenia in Myositis Patients: A Marker of Muscle Damage Associated with Myositis Severity and Disability

    Margherita Giannini1, Léa Debrut2, Anne-Laure Charles2, Mégane Pizzimenti2, Rose-Marie Javier3, Bernard Geny4 and Alain Meyer1, 1Service de Physiologie et explorations fonctionnelles, CHU, Strasbourg ; Centre de Référence des Maladies Autoimmunes Rares, CHU, Strasbourg ; UR3072, Centre de Recherche en Biomédecine, University of Strasbourg, Strasbourg, France, 2UR3072 Centre de Recherche en Biomédecine, University of Strasbourg, Strasbourg, France, 3Service de Rhumatologie, Centre de Référence des Maladies Autoimmunes Rares, University Hospital of Strasbourg, Strasbourg, France, 4Service de Physiologie et explorations fonctionnelles, CHU, Strasbourg ; UR3072 Centre de Recherche en Biomédecine, University of Strasbourg, Strasbourg, France

    Background/Purpose: Myositis are autoimmune diseases characterized by muscle inflammation and weakness. Even when disease is no longer active, a great proportion of patients does not…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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