Abstract Number: 989 • ACR/ARHP Annual Meeting 2018
Reduction of Serum IL17F and IL22 By IL23p19 Blockade with Guselkumab Is Associated with Improvement in Joint Symptoms in Psoriatic Arthritis
Background/Purpose: Guselkumab (GUS) is a fully human monoclonal antibody that binds to the p19 subunit of IL23. In a recent Phase 2 study, GUS demonstrated…Abstract Number: 1792 • ACR/ARHP Annual Meeting 2017
Distinct and Overlapping Activities of IL-17A and TNF on the Expression of Proinflammatory Cytokines and MMPs in Psoriatic Arthritis: Rationale for Anti-IL-17A/Anti-Tnfalpha Combination Therapy?
Background/Purpose: TNF and IL-17A are proinflammatory cytokines critically involved in the pathogenesis of psoriatic arthritis (PsA). Currently, targeting TNF is the first choice of a…Abstract Number: 1670 • ACR/ARHP Annual Meeting 2016
Cytokine Expression in Groups of Psoriatic Arthritis Patients Characterised By Specific HLA Genotypes and Clinical Features
Background/Purpose: Psoriatic arthritis (PsA) is a heterogeneous disease with diverse clinical and radiographic manifestations. A number of human leukocyte antigen (HLA) alleles have been found…Abstract Number: 1598 • ACR/ARHP Annual Meeting 2014
Serum Fetuin-a, Intercellular Adhesion Molecule -1 and Interleukin -18 Levels in Ankylosing Spondylitis and Psoriatic Arthritis
Background/Purpose In recent years, increased incidences of metabolic disorders have been observed in patients with systemic inflammatory rheumatic diseases. Fetuin-A, Intercellular Adhesion Molecule -1(ICAM-1) and…Abstract Number: 633 • ACR/ARHP Annual Meeting 2014
Immunological and Clinical Relationships of Synovial IL-17+ T Cells in Psoriatic Arthritis
Background/Purpose We recently reported elevated numbers of synovial fluid IL-17+CD4- T cells (mainly CD8+ (Tc17) cells) in Psoriatic Arthritis (PsA), correlating with clinical, serological and…
ACR Meeting Abstracts