Abstracts tagged "CyTOF"

Abstract Number: 900 • 2015 ACR/ARHP Annual Meeting
A Multidimensional Immunomics Approach Annotates an Immunome Shaped By the Interplay Between the Periphery and the Skin Microenvironment in Systemic Sclerosis
Hari Balaji Venkatanarayanan^1,2, Andrea Low³, Raymond Ong Jr.⁴, Liyun Lai^1,2, Juntao Li^2,5, Chie Hwee Ang^1,2, Suzan Saidin^1,2, Camillus Chua^1,2, Jing Yao Leong^1,2, Agnieszka Maliszewska^1,2, Lakshmi Ramakrishna^1,2, Julian Thumboo⁶ and Salvatore Albani^1,2, ¹SingHealth Translational Immunology and Inflammation Centre, Singapore Health Services Pte Ltd, Singapore, Singapore, ²Duke-National University of Singapore Graduate Medical School, Singapore, Singapore, ³Division of Rheumatology, Singapore General Hospital, Singapore, Singapore, ⁴Singhealth Translational Immunology and Inflammation Centre (STIIC), Singapore Health Services Pte Ltd, Singapore, Singapore, ⁵SingHealth Translational Immunology and Inflammation Centre (STIIC), Singapore Health Services Pte Ltd, Singapore, Singapore, ⁶Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore
Background/Purpose: Systemic sclerosis (SSc), is a chronic autoimmune disorder of the connective tissue. There is an unmet need to define precise immune correlates involved in…
Abstract Number: 2821 • 2015 ACR/ARHP Annual Meeting
Increased CD4 T Cell GM-CSF Production in Spondyloarthritis
M Hussein Al-Mossawi¹, Jelle De Wit², Anna Ridley³ and Paul Bowness¹, ¹Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, ²Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, ³Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, United Kingdom
Background/Purpose: Immunological, genetic and therapeutic studies have implicated the IL-17A/IL-23 inflammatory axis in SpA. GM-CSF is emerging as a cytokine that marks out a pathogenic…
Abstract Number: L12 • 2014 ACR/ARHP Annual Meeting
Immunological Phenotyping of a Cohort of American Travelers with Chikungunya Viral Arthritis
Jonathan Miner¹, Han Xian Aw yeang¹, Julie Fox¹, Samantha Taffner¹, Alfred Kim², Michael Diamond¹, Deborah Lenschow³ and Wayne Yokoyama^1,4, ¹Department of Medicine, Washington University in Saint Louis School of Medicine, Saint Louis, MO, ²Medicine, Washington University in Saint Louis School of Medicine, Saint Louis, MO, ³Washington University in Saint Louis School of Medicine, Saint Louis, MO, ⁴Howard Hughes Medical Institute, Saint Louis, MO
Background/Purpose: Chikungunya virus (CHIKV) is a rapidly emerging arthritogenic mosquito-borne alphavirus that spread to the United States in 2014. After an initial period of acute…

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