Abstracts tagged "Crystal-induced arthritis"

Abstract Number: 343 • 2019 ACR/ARP Annual Meeting
Emergency Department Length of Stay in Patients with Acute Gout
Nadine Mbuyi¹, Steven Reinert ², Ross Hilliard ³, Anthony Reginato ³ and Deepan Dalal ³, ¹George Washington University, Washington, DC, ²Lifespan Health System, Providence, RI, ³Brown University, Rhode Island Hospital, Providence, RI
Background/Purpose: Emergency department (ED) visits for acute gout increased by approximately 20% between 2006 and 2014 in the United States. (1) Reducing ED length of stay…
Abstract Number: 354 • 2019 ACR/ARP Annual Meeting
Evaluation of Opioid Analgesia in Hospitalized Patients with Acute Crystal Induced Arthritis
Sukhraj Singh¹, Anthony Ocon ¹, Mark Riley ², Jennifer Tchervenkov ¹ and Ruben Peredo-Wende ¹, ¹Albany Medical Center, Albany, NY, ²Albany Medical Center, Albany
Background/Purpose: The Opioid Epidemic has been declared a public health emergency since 2017. The use of opioids in the acute crystal induced arthritis (ACIA) population…
Abstract Number: 194 • 2018 ACR/ARHP Annual Meeting
A Survey on Gout-Related Knowledge Among Internal Medicine Residents
Sreelakshmi Panginikkod¹, Ahmad Raja², Ehsan Rajabirostami¹, Roshanak Habibi¹, Rasiya Hashim³, Sumia Matin Afridi⁴, Alvaro Altamirano Ufion⁵ and Venu Pararath Gopalakrishnan¹, ¹Internal Medicine, Presence Saint Francis Hospital, Evanston, IL, ²Presence Saint Francis Hospital, Evanston, IL, ³Presence Saint Joseph Hospital, Evanston, IL, ⁴Florida Hospital Orlando, Orlando, FL, ⁵Internal Medicine, Advocate Illinois Masonic Medical Center, Chicago, IL
Background/Purpose: The prevalence of gout has risen in recent decades despite advancements in therapeutic options due to several reasons, including lack of adherence to treatment…
Abstract Number: 870 • 2018 ACR/ARHP Annual Meeting
Patient-Reported Burden of Gout in 2017 from the United States
Puja P. Khanna¹, Douglas C.A. Taylor², An-Chen Fu² and Robert Morlock³, ¹University of Michigan, Ann Arbor, MI, ²Ironwood Pharmaceuticals, Inc., Cambridge, MA, ³YourCareChoice, Ann Arbor, MI
Background/Purpose: Gout is reported to impact 3.9% of the US adult population (Zhu. Arthritis Rheum 2011;63:3136-41). Treatment encompasses controlling acute attacks (flares) and, dependent on…
Abstract Number: 1030 • 2018 ACR/ARHP Annual Meeting
Parenteral Injection of Human Adipose-Derived Mesenchymal Stem Cells Attenuates Inflammation in an Acute Model of Gouty Arthritis
Juan Pablo Medina¹, Sandra Perez-Baos¹, Esperanza Naredo², Alberto Lopez-Reyes³, Gabriel Herrero-Beaumont⁴ and Raquel Largo⁴, ¹Joint and Bone Research Unit, IIS-Fundacion Jimenez Diaz UAM, Madrid, Spain, ²Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain, ³Synovial fluid analysis department, Instituto Nacional de Rehabilitación, Mexico City, Mexico, ⁴Bone and Joint Research Unit, Fundación Jiménez Díaz University Hospital & Health Research Institute, Madrid, Spain
Background/Purpose: The regenerative and immunomodulatory properties of Adipose-Derived Mesenchymal Stem Cells (ASCs) make them a potential therapeutic approach for the treatment of chronic inflammatory diseases,…
Abstract Number: 1260 • 2018 ACR/ARHP Annual Meeting
Predictors of Hospitalization Due to Acute Gout: A Retrospective Cohort Study
Nadine Mbuyi¹, Isha Shah², Steven Reinert³, Grayson Baird⁴, Pieusha Malhotra⁵, Ross Hilliard⁶ and Deepan Dalal⁷, ¹Rheumatology, The Warren Alpert Medical School of Brown University, Providence, RI, ²Internal Medicine, The Warren Alpert Medical School of Brown University, Providence, RI, ³Lifespan Information Services, Lifespan Information Services, Providence, RI, Providence, RI, ⁴Department of Biostatistics, Lifespan, Rhode Island Hospital, Providence, RI, ⁵Rheumatology, Roger William Medical Center, Providence, RI, Providence, RI, ⁶Medicine, The Warren Alpert Medical School of Brown University, Providence, RI, ⁷Medicine/Rheumatology, The Warren Alpert Medical School of Brown University, Providence, RI
Background/Purpose: Despite effective treatments, hospitalization due to acute gout is increasing and is financially burdensome. Prior studies have primarily attributed the increased rate of gout…
Abstract Number: 1268 • 2018 ACR/ARHP Annual Meeting
Assessment of the Persistence of Crystals Under Polarised Light Microscopy in Stored Synovial Fluid Samples
Sonia Pastor¹, Rocio Caño², Silvia Gomez-Sabater² and Mariano Andrés^1,3, ¹Departamento de Medicina Clínica, Universidad Miguel Hernández, Alicante, Spain, ²Seccion de Reumatologia, Hospital General Universitario de Alicante-ISABIAL, Alicante, Spain, ³Hospital General Universitario de Alicante-ISABIAL, Alicante, Spain
Background/Purpose: Lacking an immediate access to a polarized light microscope is sometimes used to justify the clinical diagnosis of crystal-related arthritis. Some studies have assessed…
Abstract Number: 1273 • 2018 ACR/ARHP Annual Meeting
What Did Patients from the US Think about Their Gout in 2017?
Puja P. Khanna¹, Douglas C.A. Taylor², An-Chen Fu² and Robert Morlock³, ¹University of Michigan, Ann Arbor, MI, ²Ironwood Pharmaceuticals, Inc., Cambridge, MA, ³YourCareChoice, Ann Arbor, MI
Background/Purpose: The impact of chronic gout and acute flares on daily activities is severely limiting. Yet only 40% of gout patients receive urate-lowering therapy (ULT),…
Abstract Number: 1980 • 2018 ACR/ARHP Annual Meeting
Comprehensive Association Analysis between Rare and Common ABCG2 Variants and Gout Susceptibility
Hirotaka Matsuo¹, Toshihide Higashino¹, Tappei Takada², Hirofumi Nakaoka³, Yu Toyoda⁴, Blanka Stiburkova⁵, Hiroshi Nakashima⁶, Seiko Shimizu¹, Makoto Kawaguchi⁷, Akiyoshi Nakayama⁸, Yuka Aoki¹, Misaki Ishino¹, Yusuke Kawamura¹, Kenji Wakai⁹, Rieko Okada¹⁰, Tatsuo Hosoya¹¹, Kimiyoshi Ichida¹², Hiroshi Ooyama¹³, Hiroshi Suzuki², Ituro Inoue³, Tanya J. Major¹⁴, Tony R. Merriman¹⁴ and Nariyoshi Shinomiya¹, ¹Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Japan, ²Department of Pharmacy, The University of Tokyo Hospital, Faculty of Medicine, The University of Tokyo, Tokyo, Japan, ³Division of Human Genetics, Department of Integrated Genetics, National Institute of Genetics, Mishima, Japan, ⁴Department of Pharmacy, The University of Tokyo Hospital, Faculty of Medicine,, The University of Tokyo, Tokyo, Japan, ⁵Department of Pediatrics and Adolescent Medicine, Charles University and General University Hospital in Prague, First Faculty of Medicine, Prague, Czech Republic, ⁶Department of Preventive Medicine and Public Health, National Defense Medical College, Tokorozawa, Japan, ⁷National Defense Medical College, Tokorozawa, Japan, ⁸Dept Integrative Physiol, National Defense Medical College, Tokorozawa, Japan, ⁹Nagoya University Graduate School of Medicine, Nagoya, Japan, ¹⁰Department of Preventive Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan, ¹¹Division of Kidney and Hypertension, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan, ¹²Department of Pathophysiology, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan, ¹³Ryougoku East Gate Clinic, Tokyo, Japan, ¹⁴University of Otago, Dunedin, New Zealand
Background/Purpose: We have reported that ABCG2 has an important role in both renal and intestinal urate excretion and these common variants as rs72552713 (Q126X) and…
Abstract Number: 249 • 2017 ACR/ARHP Annual Meeting
Where to Look for Uric Acid Crystals? Results from a Norwegian Ultrasound Study
Hilde B Hammer¹, Lars Karoliussen², Lene Terslev³, Espen A. Haavardsholm⁴, Tore K Kvien⁵ and Till Uhlig⁴, ¹Rheumatology, Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ³Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark, Copenhagen, Denmark, ⁴Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁵On behalf of the NOR-DMARD registry, Oslo, Norway
Background/Purpose: Ultrasound (US) has received an increasing attention in detecting uric monosodium urate (MSU) deposits, and is included in the ACR/EULAR classification criteria for gout.…
Abstract Number: 1132 • 2017 ACR/ARHP Annual Meeting
Compensated Polarized Microscopy for Crystal Identification Shows High Reliability Among Multiple Observers
José Antonio Bernal¹, Mariano Andrés^2,3, Salvador López-Salguero⁴, Vega Jovaní⁵, Paloma Vela^3,6 and Eliseo Pascual⁷, ¹Reumatología, Hospital Universitario del Vinalopó, Elche, Spain, ²Reumatología, Hospital General Universitario Alicante, Alicante, Spain, ³Universidad Miguel Hernández, Elche, Spain, ⁴Sección de Reumatología, Hospital General Universitario de Alicante, Alicante, Spain, ⁵Reumatología, Hospital general universitario de Alicante, Alicante, Spain, ⁶Reumatología, Hospital General Universitario de Alicante. Alicante. Spain, Alicante, Spain, ⁷Emeritus Professor, Universidad Miguel Hernández, Elche, Spain
Background/Purpose: The gold standard for crystal-related arthritis diagnosis remains synovial fluid analysis by a microscope fitted with compensated polarized filters as it has been shown…
Abstract Number: 2055 • 2017 ACR/ARHP Annual Meeting
Omeract Ultrasonographic Criteria for the Diagnosis of Calcium Pyrophosphate Deposition Disease at the Metacarpal-Phalangeal, Wrist, Acromion-Clavicular and Hip Joints: An Inter-Observer and Intra-Observer Reliability Study
Pascal Zufferey¹, Georgios Filippou², Carlo Alberto Scirè³, Nemanja Damjanov⁴, MA D'Agostino⁵, George A. W. Bruyn⁶, Antonella Adinolfi², Greta Carrara⁷, Valentina Di Sabatino⁸, Andrea Delle Sedie⁹, Tomas Cazenave¹⁰, Carlos Pineda¹¹, Francesco Porta¹², Daryl K. MacCarter¹³, Emilio Filippucci¹⁴, Frédérique Gandjbakhch¹⁵, Ingrid Moller¹⁶, Anthony Reginato¹⁷, Mihaela Cosmina Micu¹⁸, Mohamed Mortada¹⁹, Gaël Mouterde²⁰, Lene Terslev²¹, Esperanza Naredo²², Valentina Picerno², Wolfgang A. Schmidt²³, Violeta Vlad²⁴, Florentin Ananu Vreju²⁵ and Annamaria Iagnocco²⁶, ¹Department of Rheumatology, University Hospital Lausanne, Lausanne, Switzerland, ²University of Siena, Siena, Italy, ³Epidemiology Unit -Italian Society for Rheumatology, Milano, Italy, ⁴Institute of Rheumatology, Belgrade University School of Medicine, Belgrade, Serbia, ⁵Rheumatology, Versailles-Saint Quentin en Yvelines University, Boulogne-Billancourt, France, ⁶Rheumatology, MC Groep, Loenga, Netherlands, ⁷Epidemiology Unit, Italian Society for Rheumatology, Milano, Italy, ⁸CMV, Grosseto, Italy, ⁹University of Pisa, Rheumatology Unit, Pisa, Italy, ¹⁰Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ¹¹Biomedical Research, Instituto Nacional de Rehabilitacion, Mexico City, Mexico, ¹²Hospital of Pistoia, Pistoia, Italy, ¹³Coeur d'Alene Arthritis Clinic, Coeur d'Alene, ID, ¹⁴Clinical Reumatologica, Universita Politecnica delle Marche, Ancona, Italy, ¹⁵Service de Rhumatologie, GH Pitié-Salpétrière, MD, Paris, France, ¹⁶Instituto de Poal, Barcelona, Spain, ¹⁷Rheumatology, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, ¹⁸Division of Rheumatology, Department of Rehabilitation II, Clinical Rehabilitation Hospital, Cluj Napoca, Romania, ¹⁹zagazig university, Zagazig, Egypt, ²⁰Rheumatology Department, Hopital Lapeyronie, Montpellier, France, ²¹Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark, Copenhagen, Denmark, ²²Rheumatology Department, Hospital Gregorio Marañón, Madrid, Spain, ²³Med Ctr Rheumatology Berlin Buch, Immanuel Krankenhaus Berlin, Berlin, Germany, ²⁴RCRD Research Center, Bucharest, Romania, ²⁵University of Medicine and Pharmacy, Department of Rheumatology, Craiova, Romania, ²⁶Academic Rheumatology Unit, Università degli Studi di Torino, Torino, Italy
Background/Purpose: The OMERACT US subtask force “US in CPPD” has recently created the definitions for US identification of crystal deposits in joints and tested the…
Abstract Number: 2081 • 2017 ACR/ARHP Annual Meeting
Synovial Fluid Leukocyte Count and Its Association with Crystal Deposition in Asymptomatic Hyperuricemia
Mariano Andrés^1,2, José Antonio Bernal³, María Dolores Arenas⁴ and Eliseo Pascual^1,5, ¹Sección de Reumatología, Hospital General Universitario de Alicante, Alicante, Spain, ²Departamento de Medicina Clínica, Universidad Miguel Hernández, Alicante, Spain, ³Reumatología, Hospital Universitario del Vinalopó, Elche, Spain, ⁴Unidad de Nefrología, Hospital Vithas Perpetuo Socorro, Alicante, Spain, ⁵Emeritus Professor, Universidad Miguel Hernández, Elche, Spain
Background/Purpose: Articular and periarticular deposits of monosodium urate (MSU) crystals in asymptomatic hyperuricemia (AH) may associate with more severe forms of atherosclerosis [Andrés 2016]. This…
Abstract Number: 2090 • 2017 ACR/ARHP Annual Meeting
Utility of Anakinra in Acute Crystalline Diseases: A Retrospective Study Comparing a University Hospital with Veterans Affairs Medical Center
Julianna Desmarais¹ and Cong-Qiu Chu², ¹Department of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, OR, ²Rheumatology, Oregon Health & Science University, Portland, OR
Background/Purpose: Anakinra is an IL-1 blocking medication used off label to relieve acute inflammation from gout and pseudogout. The efficacy and safety of this treatment…
Abstract Number: 2896 • 2017 ACR/ARHP Annual Meeting
Human Cartilage Influences the Crystallization of Monosodium Urate; Understanding the Link between Gout and Osteoarthritis
Ashika Chhana¹, Bregina Pool², Ally Choi¹, Ryan Gao¹, Mark Zhu¹, Jillian Cornish², Jacob Munro³ and Nicola Dalbeth⁴, ¹Medicine, University of Auckland, Auckland, New Zealand, ²Department of Medicine, University of Auckland, Auckland, New Zealand, ³Orthopaedics, Auckland City Hospital, Auckland, New Zealand, ⁴University of Auckland, Auckland, New Zealand
Background/Purpose: Monosodium urate (MSU) crystal deposition and gout flares frequently affect joints that have been damaged or are affected by osteoarthritis. The aim of…