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Abstracts tagged "Crystal-induced arthritis"

  • Abstract Number: 1145 • ACR Convergence 2022

    The Prostate Plays a Role in Serum Urate Levels and the Risk of Gout in Men

    Mariana Urquiaga1, Megan Leask1, Nicholas Sumpter1, Brooke Maxwell2, Sara Lewis2, Eric E. Kelley2 and Tony Merriman3, 1University of Alabama at Birmingham, Birmingham, AL, 2West Virginia University, Morgantown, WV, 3University of Otago, Dunedin, New Zealand

    Background/Purpose: Men have higher serum urate (SU) and increased prevalence of gout compared to pre-menopausal women. Xanthine oxidoreductase (XOR), encoded by the XDH gene, is…
  • Abstract Number: 1791 • ACR Convergence 2022

    Point-of-Care Multi-Energy Photon-Counting CT for Earlier Non-Invasive Diagnosis of Gout and Calcium Pyrophosphate Deposition Disease

    Fabio Becce1, Anais Viry2, Damien Racine2, David Rotzinger1, Tristan Pascart3, Georgios Filippou4, Jérôme Damet2 and Lucia Gallego Manzano2, 1Lausanne University Hospital (CHUV), Lausanne, Switzerland, 2Institute of Radiation Physics, Lausanne, Switzerland, 3Groupement Hospitalier de l'Institut Catholique de Lille, Lomme, France, 4Rheumatology Department, Luigi Sacco University Hospital, Siena, Italy

    Background/Purpose: While the definitive diagnosis of gout and calcium pyrophosphate deposition disease (CPPD) is still based on the identification of characteristic crystals in synovial fluid…
  • Abstract Number: 1801 • ACR Convergence 2022

    High Frequency of Structural Damage in the Lower Spine of Patients with Chondrocalcinosis

    Kalliopi Klavdianou1, Jona Kasfeld2, Martin Fruth3, Styliani Tsiami4, Juergen Braun5, Philipp Sewerin6, David Kiefer5 and Xenofon Baraliakos7, 1'Asklepieion' General Hospital, Department of Rheumatology, Voula, Athens, Greece, 2Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 3Blikk, Radiologie, Herne, Germany, 4Rheumazentrum Ruhrgebiet, Herne, Ruhr-University Bochum, Herne, Germany, 5Rheumazentrum Ruhrgebiet, Herne, Germany, 6Rheumazentrum Ruhrgebiet, Ruhr-Universität-Bochum, Herne, Germany, 7Rheumazentrum Ruhrgebiet Herne, Herne, Germany

    Background/Purpose: Calcium pyrophosphate dihydrate crystal deposition disease (CPPD, chondrocalcinosis) is known to affect fibrocartilaginous tissue in the large and smaller peripheral joints. The affection of…
  • Abstract Number: 1804 • ACR Convergence 2022

    Raman Spectroscopy Integrated with Polarized Light Microscopy for Diagnosis of Crystallopathies

    Tom Niessink1, Matthijs Janssen2, Cees Otto1 and Tim Jansen3, 1Medical Cell Biophysics group, University of Twente, Enschede, Netherlands, 2Rijnstate Hospital, Bennekom, Netherlands, 3Department of Rheumatology, VieCuri Medical Centre, Venlo, Netherlands

    Background/Purpose: The current golden standard in diagnosing gout and calcium pyrophosphate deposition is polarized light microscopy (PLM). However, small crystal sizes, the presence of other…
  • Abstract Number: 1813 • ACR Convergence 2022

    Patient-Reported Outcomes in CPPD Compared to Gout and Osteoarthritis

    Mary Grace Whelan1, Keigo Hayashi2 and Sara Tedeschi1, 1Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Okayama, Japan

    Background/Purpose: Calcium pyrophosphate deposition (CPPD) disease prevalence is similar to gout and osteoarthritis (OA), yet CPPD outcomes research greatly lags behind these other forms of…
  • Abstract Number: 1817 • ACR Convergence 2022

    Acute Coronary Syndrome in Calcium Pyrophosphate Deposition Disease Patients: A Cross-sectional Study from the National Inpatient Sample

    Konstantinos Parperis1 and Bikash Bhattarai2, 1University of Cyprus Medical School, Nicosia, Cyprus, 2Valleywise Health, Phoenix, AZ

    Background/Purpose: Calcium pyrophosphate deposition disease (CPPD) is a common crystal-induced arthritis characterized by the deposition of calcium pyrophosphate crystals in the articular tissues. Acute CPP…
  • Abstract Number: 1825 • ACR Convergence 2022

    Vascular Calcifications Adjacent to the Involved Joint of Patients Diagnosed with Calcium Pyrophosphate Crystal Arthritis – a Retrospective Observational Study

    Shay Brikman1, Amir Bieber2 and Reuven Mader1, 1Rheumatic Diseases Unit, Emek Medical Center, Afula, Israel, 2Emek Medical Center, Raanana, Israel

    Background/Purpose: Prior studies have shown an association between chondrocalcinosis (CC) and vascular calcifications. In this study, we aimed to assess the presence of vascular calcifications…
  • Abstract Number: 1900 • ACR Convergence 2022

    CoLchicine for Treatment of OsteoArthritis of the Knee (CLOAK)-A Double-blind, Placebo-controlled Trial

    Jonathan Samuels1, Michael Pillinger2, Michael Toprover3, Svetlana Krasnokutsky Samuels4, Apoorva Patil5, Fernando Bomfim6, Renata La Rocca Vieira6, David Wei5, Sydney Catron5, Maryfe coronel5, Annie Kim5 and Sarah Moussavi5, 1NYU Langone, Rye Brook, NY, 2NYU Grossman School of Medicine, New York, NY, 3Division of Rheumatology, New York University Grossman School of Medicine and Rheumatology Section, New York Harbor Health Care System, New York Campus of the U.S. Department of Veterans Affairs, New York, NY, 4Westmed, Rye Brook, NY, 5NYU Langone Health, New York, NY, 6NYU Langone, New York, NY

    Background/Purpose: Knee osteoarthritis (OA) is an inflammatory disease, with a probable role for IL-1b. Calcium and urate crystals may promote OA by activating the NLRP3…
  • Abstract Number: 2208 • ACR Convergence 2022

    Diagnostic Performance of Hip Ultrasound in Calcium Pyrophosphate Deposition Disease

    Carina Soto-Fajardo1, Fabian Carranza-Enriquez2, Sinthia Solorzano Flores2, Abish Angeles2, Paola Flores2, Raul Pichardo-Bahena2, Luis Javier Jara Quezada2, Angélica Peña Ayala2, Victor-Manuel Ilizaliturri-Sanchez2, Georgios Filippou3 and Carlos Pineda2, 1Instituto Nacional de Rehabilitacion "Luis Guillermo Ibarra Ibarra", Ciudad de México, Mexico, 2Instituto Nacional de Rehabilitacion, Ciudad de México, Mexico, 3Rheumatology Department, Luigi Sacco University Hospital, Siena, Italy

    Background/Purpose: Calcium Pyrophosphate Deposition Disease (CPPD) is a chronic and potentially incapacitating disease. The reference standard for its diagnosis is the identification of calcium pyrophosphate…
  • Abstract Number: 1898 • ACR Convergence 2021

    Risk of Major Adverse Cardiovascular Events in a Large Cohort of Patients with Acute Calcium Pyrophosphate Crystal Arthritis

    Sara Tedeschi1, Weixing Huang1, Kazuki Yoshida1 and Daniel Solomon2, 1Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Newton, MA

    Background/Purpose: Acute calcium pyrophosphate (CPP) crystal arthritis, also known as pseudogout, causes an acute inflammatory arthritis that shares clinical similarities with gout. We investigated the…
  • Abstract Number: 0580 • ACR Convergence 2021

    Association Between Female Reproductive Factors and Gout: A Nationwide Population-based Cohort Study of 1 Million Postmenopausal Women

    Yeonghee Eun1, In Young Kim2, Kyungdo Han3, Kyu Na Lee3, Dong-Yun Lee1, Dong Wook Shin1, Seonyoung Kang1, Seulkee Lee1, Hoon-Suk Cha1, Eun-Mi Koh1, Jaejoon Lee1 and Hyungjin Kim1, 1Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea, 2National Police Hospital, Seoul, Republic of Korea, 3Soongsil University, Seoul, Republic of Korea

    Background/Purpose: Previous studies have shown that the incidence and risk factors of gout differs according to sex. However, little research has been done on the…
  • Abstract Number: 0582 • ACR Convergence 2021

    Altered Risk of Gout According to Change of Metabolic Parameters in Young Adults

    Yeonghee Eun1, In Young Kim2, Kyungdo Han3, Seonyoung Kang1, Seulkee Lee1, Hoon-Suk Cha1, Eun-Mi Koh1, Hyungjin Kim1 and Jaejoon Lee1, 1Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea, 2National Police Hospital, Seoul, Republic of Korea, 3Soongsil University, Seoul, Republic of Korea

    Background/Purpose: Previous studies have shown a link between gout and metabolic syndrome (MetS). It is well known that lifestyle modifications such as weight reduction and…
  • Abstract Number: 0666 • ACR Convergence 2021

    Process Mapping Gout Hospitalizations: A Deep Dive into an Avoidable Epidemic

    Mark Russell1, Benjamin Ellis2, Benjamin Clarke1, Deepak Nagra1 and James Galloway3, 1King's College London, London, United Kingdom, 2Imperial College Healthcare NHS Trust, London, United Kingdom, 3Kings College London, London, United Kingdom

    Background/Purpose: Hospital admissions for gout flares have increased dramatically in recent years. Strategies to reduce hospitalizations and improve uptake of urate-lowering therapy (ULT) are needed.…
  • Abstract Number: 0667 • ACR Convergence 2021

    Active Screening for Gout Permits Identifying a Larger Cardiovascular Population at High Mortality Risk

    Silvia Ruiz-Simón1, Irene Calabuig2, Miguel Gómez-Garberí3 and MARIANO ANDRES4, 1Universidad Miguel Hernández, Alicante, Spain, 2Hospital General Universitario de Alicante, Alicante, Spain, 3Hospital Universitario San Juan de Alicante, San Juan de Alicante, Spain, 4Hospital General Universitario de Alicante-ISABIAL, Alicante, Spain

    Background/Purpose: We have recently noted by active screening that about a third of gout cases in the cardiovascular population is not registered in records (Calabuig,…
  • Abstract Number: 0679 • ACR Convergence 2021

    Cardiovascular Risk Associated with Treatment of Allopurinol and Benzbromarone in Patients with Gout

    Yeonghee Eun, Seonyoung Kang, Seulkee Lee, Hyungjin Kim, Jaejoon Lee, Eun-Mi Koh and Hoon-Suk Cha, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea

    Background/Purpose: Previous studies have shown that cardiovascular risk is increased in patients with gout. There are many studies on the effect of uric acid lowering…
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