ACR Meeting Abstracts

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Abstracts tagged "Crystal-induced arthritis"

  • Abstract Number: 0281 • ACR Convergence 2024

    Intra-articular Treatment Combining Sustained Release Colchicine Encapsulated in Microspheres, and Ropivacaine, Is Effective in Inflammatory Arthritis in Rats

    Julien GRASSOT1, Farah MARZOUKI2, Roxane HERVE3, Magali BECKLER4, Luca SEMERANO5, Natacha BESSIS6, Elodie RIVIERE7, Charles SANSON2, Gauthier POULIQUEN2, Philippe POULETTY8 and Marie-Christophe BOISSIER9, 1PK MED, LYON, Rhone-Alpes, France, 2PK MED, LYON, France, 3INSERM U1125, Bobigny, France, 4INSERM 1125, Bobigny, France, 5Avicenne Teaching Hospital APHP, Bobigny, France, 6INSERM, Université Sorbonne Paris Nord, PARIS, France, 7INSERM, Université Sorbonne Paris Nord, APHP, PARIS, France, 8PK MED, PARIS, France, 9University Sorbonne Paris Nord, Bobigny, France

    Background/Purpose: Gout is a common disease with a prevalence and incidence on the rise worldwide. However, approved treatments to treat acute gout flares have slow…
  • Abstract Number: 0282 • ACR Convergence 2024

    Electronic Health Record-Based Calcium Pyrophosphate Deposition Disease Registry: A Feasibility Study

    Nils Bürgisser1, Denis Mongin2, Samia Mehouachi2, Delphine Sophie Courvoisier3 and Kim Lauper4, 1Division of Rheumatology and internal medicine, Geneva University Hospital, Switzerland, Geneva, Switzerland, 2Division of Rheumatology, Geneva University Hospital, Switzerland, Geneva, Switzerland, 3Division of Rheumatology, Geneva University Hospitals, Geneva, Switzerland, 4Geneva University Hospitals, Geneva, Switzerland

    Background/Purpose: Despite its prevalence, calcium pyrophosphate deposition disease (CPPD) remains insufficiently studied. Leveraging electronic health record (EHR) data, a rich source of patient information, could…
  • Abstract Number: 0284 • ACR Convergence 2024

    Identification of Calcium Pyrophosphate Deposition Using Ultrasonography in Patients with a Suspected Diagnosis of Seronegative Rheumatoid Arthritis

    Joanna Potera1, Angelo Gaffo2, Alvin Day3, Mariana Urquiaga2 and Amanda Alexander4, 1University of Alabama at Birmingham, Irondale, AL, 2University of Alabama at Birmingham, Birmingham, AL, 3Dept. of Veterans Affairs, Lexington, SC, 4University of Alabama at Birmingham, Homewood, AL

    Background/Purpose: Calcium pyrophosphate deposition disease is a common condition that can cause chronic polyarticular inflammatory joint disease, which sometimes resembles rheumatoid arthritis. Misdiagnosis is especially…
  • Abstract Number: 1071 • ACR Convergence 2024

    Rapid Access Microscopy and Real Time Case Discussion via a Secure Messaging App Improves Diagnostic Accuracy and Management of Acute Hot Swollen Joints

    Anouchka Lewis1, John Stack2, Oisin Corish2, Callum Swift2, Tomás Breslin2, Frank Lyons2, Eavan Muldoon2, Cian McDermott2, Sharon Cowley2, Helina Alemayehu2, Oliver Boughton2, Khaled Taha2 and Geraldine McCarthy2, 1The Mater Misericordiae University Hospital, Dublin, Ireland, 2Mater Misericordiae University Hospital, Dublin, Ireland

    Background/Purpose: Patients with acute swollen joints are often presumed to have septic arthritis, leading to treatment with intravenous antibiotics and arthroscopic washout. Previously at our…
  • Abstract Number: 1083 • ACR Convergence 2024

    Comparison of a Handheld Ultrasound Device with Cart-Based Ultrasound for the Assessment of Gout Lesions in People with Established Gout

    Rachel Murdoch1, Lene Terslev2, Julia Martin3, Borislav Mihov1, Gregory Gamble1, Søren Torp-Pedersen4, Anne Horne1 and Nicola Dalbeth1, 1University of Auckland, Auckland, New Zealand, 2Rigshospitalet-Glostrup & COPECARE, Glostrup, Denmark, 3Te Whatu Ora Te Toka Tumai, Auckland, New Zealand, 4Rigshospitalet, Copenhagen, Denmark

    Background/Purpose: Ultrasound is frequently used in rheumatology practice to assist with the diagnosis of rheumatic and musculoskeletal diseases. In patients with gout, it allows visualization…
  • Abstract Number: 1092 • ACR Convergence 2024

    Chronic Kidney Disease Is Associated with Increased Glucose Uptake-associated Metabolic Activity of Visceral Adipose and Subcutaneous Adipose Tissue in Gout Patients

    Shunya Kaneshita1, Sho Fukui2, Soheil Niku3, KWANGHOON LEE4, Ernest Belezzuoli3, Robert Terkeltaub5 and Monica Guma6, 1UCSD, Miyazu city, Kyoto, Japan, 2Brigham and Women's Hospital, Brookline, MA, 3UCSD, La Jolla, 4UCSD, San Diego, CA, 5Retired, San Diego, CA, 6UCSD, La Jolla, CA

    Background/Purpose: Gout, a condition characterized by elevated uric acid levels, is linked to multiple complications, including coronary artery disease, hypertension, and type 2 diabetes mellitus.…
  • Abstract Number: 1094 • ACR Convergence 2024

    Longitudinal Analysis of Serum Urate in Prediabetic Phase

    Javier Marrugo1, Leah Santacroce1, Misti Paudel2, Sho Fukui3, Sara Tedeschi1 and Daniel Solomon4, 1Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Division of Rheumatology, Inflammation, and Immunity, Boston, MA, 3Brigham and Women's Hospital, Brookline, MA, 4Brigham and Women's Hospital, Newton, MA

    Background/Purpose: More than 460 million people worldwide are currently living with prediabetes, a condition that not only predisposes individuals to diabetes (DM) but also to…
  • Abstract Number: 1095 • ACR Convergence 2024

    The Incidence of Gout Among Individuals with Hyperuricemia over Time – an Insight from a Nationwide Cohort Study

    Shay Brikman1, Amir Bieber2, Liel Serfaty, MA3, Ran Abuhasira, MD, PhD4, Nadav Rappoport5 and Naomi Schlesinger6, 1Emek Medical Center, Afula, Israel, 2Emek Medical Center, Clalit Health Services, Raanana, Israel, 3Department of Software and Information Systems Engineering, Ben-Gurion University of the Negev, Be'er Sheva, Israel, 4Clinical Research Center, Soroka University Medical Center, Be'er Sheva, Israel, 5Ben-Gurion University of the Negev, Beer-Sheva, Israel, 6University of Utah, Salt Lake City, UT

    Background/Purpose: Hyperuricemia is considered the most important risk factor for developing Gout, the most common adult inflammatory arthritis. Hyperuricemia is defined by a serum urate…
  • Abstract Number: 1103 • ACR Convergence 2024

    The Role of Renal Dual-Energy CT in Exploring the Gouty Kidney: The RENODECT Study

    Tristan Pascart1, Elie Dauphin1, Chio Yokose2, Charlotte Jauffret3, Hyon K. Choi4 and Jean-François Budzik5, 1Université Catholique de Lille, Lille, Nord-Pas-de-Calais, France, 2Massachusetts General Hospital, Boston, MA, 3Lille Catholic University, Lille, Nord-Pas-de-Calais, France, 4Massachusetts General Hospital, Lexington, MA, 5Lille Catholic University, Lille, France

    Background/Purpose: Chronic kidney disease (CKD) is a common feature in gout, and can have multiple causes, some of which are gout specific, such as gout…
  • Abstract Number: 0267 • ACR Convergence 2024

    IL-17 Participates in the Pathogenesis of Chronic Gouty Arthritis

    Hong Di1, Xinxin Han1, Yun Zhang2 and Xuejun Zeng1, 1Peking Union Medical College Hospital, Beijing, China, 2Peking Union Medical College Hospital (CAMS), Beijing, China

    Background/Purpose: Chronic gouty arthritis (CGA) is different from acute gouty arthritis  (AGA), its main characteristics include repeated or even persistent joint symptoms, tophus and bone destruction.…
  • Abstract Number: 1653 • ACR Convergence 2024

    Osteoarthritis Drives Inflammatory Imprinting of Synovial Fibroblasts, Exacerbating Gouty Arthritis Through m6A Modification of S100A4

    ZIYI CHEN1, Yinghui Hua2 and Wenjuan Wang1, 1Department of Sports Medicine, Huashan Hospital,Fudan University, Shanghai, Shanghai, China (People's Republic), 2Department of Sports Medicine, Huashan Hospital,Fudan University, Shanghai, China (People's Republic)

    Background/Purpose: Patients with osteoarthritis (OA) face an elevated risk of future gouty arthritis (GA). To delineate the underlying cellular and molecular mechanisms of OA-driven gout…
  • Abstract Number: 0270 • ACR Convergence 2024

    Longitudinal Patterns of C-Reactive Protein Values in Calcium Pyrophosphate Deposition (CPPD) Disease

    Muneet Gill, Hongshu Guan, Jamie Collins and Sara Tedeschi, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Calcium pyrophosphate deposition (CPPD) disease is a crystalline arthritis affecting older adults. Systemic inflammation occurs during flares of acute calcium pyrophosphate (CPP) crystal arthritis…
  • Abstract Number: 2013 • ACR Convergence 2024

    Elevated Serum Allantoin and Allantoin/uric Acid Ratio as Indicators of Oxidative Stress in Severe Gout and Cardiovascular Comorbidities

    Lenka Hasikova1, Petr Kozlik2, Kveta Kalikova3, Petr Dusek4, Marketa Pavlikova1, Blanka Stiburkova5 and Jakub Závada6, 1Institute of Rheumatology, Prague, Czech Republic; Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, 2Department of Analytical Chemistry, Faculty of Science, Charles University, Prague, Czech Republic, Prague, Czech Republic, 3Department of Physical and Macromolecular Chemistry, Faculty of Science, Charles University, Prague, Czech Republic, Prague, Czech Republic, 4Department of Neurology and Centre of Clinical Neuroscience and Department of Radiology, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic, Prague, Czech Republic, 5Institute of Rheumatology, Prague, Czech Republic and Department of Paediatrics and Inherited Metabolic Disorders, 1st Faculty of Medicine, Charles University and General University Hospital in Prague, Czech Republic, Prague, Czech Republic, 6Institute of Rheumatology and Charles University, Praha, Czech Republic

    Background/Purpose: Uric acid (UA) can be non-enzymatically oxidized into allantoin and other products by reactive oxygen species under conditions of increased oxidative stress. Consequently, allantoin…
  • Abstract Number: 0272 • ACR Convergence 2024

    Calcifications of the Transverse Ligament of the Atlas in Patients Diagnosed with Calciumpyrophosphate Crystal Arthritis – a Retrospective Observational Study

    Shay Brikman1, Noga Shabshin2 and Amir Bieber3, 1Emek Medical Center, Afula, Israel, 2Emek Medical Center, Clalit Health Services, Afula, Israel, 3Emek Medical Center, Clalit Health Services, Raanana, Israel

    Background/Purpose: Chondrocalcinosis (CC) is commonly detected on X-ray films of the knee, wrist, and symphysis pubis. Calcium pyrophosphate (CPP) deposition disease is sometimes associated with…
  • Abstract Number: 2016 • ACR Convergence 2024

    Treat to Target in Gout Yields Superior Outcomes Compared to Treat to Avoid Symptoms Approach (results from the Gout TrEatment Strategy Overture Trial)

    Anusha Moses1, Martijn Oude Voshaar1, Tim L.Th. Jansen2 and Mart Van De Laar1, 1University of Twente, Enschede, The Netherlands, Enschede, Overijssel, Netherlands, 21VieCuri Medisch Centrum, Venlo, Netherlands

    Background/Purpose: Both the European League Against Rheumatism (EULAR) and the American College for Rheumatology (ACR) state that gout can be effectively managed by reducing sUA…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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