ACR Meeting Abstracts

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Abstracts tagged "COVID-19"

  • Abstract Number: 0141 • ACR Convergence 2022

    Is Rituximab Associated with Worse Outcomes in COVID-19 Patients? A Meta-analysis

    Yasmin Gerais1, Chenyu Sun1, Bethany King2, Scott Lowe3, Biniyam Mohammed1, Rachel Bentley3, Yaru Li4, Binyu Wei5 and Chuanhui Xu6, 1Ascension Saint Joseph hospital, Chicago, IL, 2MercyOne Des Moines Medical center, Des Moines, IA, 3College of Osteopathic Medicine, Kansas City University, Kansas, MO, 4Swedish Hospital, Chicago, IL, 5Harvard Medical School, Boston, MA, 6Tan Tock Seng Hospital, Singapore, Singapore

    Background/Purpose: Rituximab targets the CD20 antigen to deplete B cells and is indicated for a number of autoimmune diseases and other conditions. Accumulating data suggest…
  • Abstract Number: 0508 • ACR Convergence 2022

    Detecting the Critical Factors in the Pathogenesis of Anti-melanoma Differentiation-associated Gene 5–positive Dermatomyositis (MDA5 DM) by Gene Expression Analysis of Peripheral Blood

    Yoshinobu Koyama1, Yoshiharu Sato2, Yu Nakai1 and Moe Sakamoto1, 1Japanese Red Cross Okayama Hospital, Okayama, Japan, 2DNA Chip Research Inc, Tokyo, Japan

    Background/Purpose: MDA5 DM is a distinct subtype of DM that is characterized by high mortality due to rapid progressive interstitial lung disease (ILD). MDA5 is…
  • Abstract Number: 0751 • ACR Convergence 2022

    Accessing Telehealth and In-Person Healthcare During the COVID-19 Pandemic: Experiences of Individuals with Rheumatoid Arthritis

    Smruthi Ramachandran1, Jenny Leese2, Stephanie Therrien3, Catherine L. Backman1, Jasmin Ma4, Kelly English5, Eileen Davidson6, Shanon McQuitty7, Alison Hoens5, Cheryl Koehn8, James Gavin9, jo Adams9 and Linda Li1, 1University of British Columbia, Vancouver, BC, Canada, 2University of Ottawa, Ottawa, ON, Canada, 3Arthritis Research Canada, Vancouver, BC, Canada, 4Arthritis Research Canada/University of British Columbia, Richmond, BC, Canada, 5Arthritis Patient Advisory Board of Arthritis Research Canada, Vancouver, BC, Canada, 6Arthritis Patient Advisory Board of Arthritis Research Canada, Burnaby, BC, Canada, 7Arthritis Patient Advisory Board of Arthritis Research Canada, Richmond, BC, Canada, 8Arthritis Consumer Experts, Vancouver, BC, Canada, 9University of Southampton, Southampton, United Kingdom

    Background/Purpose: The COVID-19 pandemic has provided opportunity to increase integration of virtual healthcare with in-person medical practices. Individuals with rheumatoid arthritis (RA) continue to self-manage…
  • Abstract Number: 0786 • ACR Convergence 2022

    Humoral and T-cell Responses to SARS-CoV-2 Vaccination in Patients with Rheumatoid Arthritis

    Carolina A Isnardi1, Osvaldo Luis Cerda1, MARGARITA LANDI2, Leonel Cruces3, Emilce Edith Schneeberger1, Claudia Calle montoro2, Maria Agustina Alfaro4, Brian Manases roldan4, Andrea Belen Gomez Vara1, Pamela Giorgis4, Roberto Alejandro Ezquer4, María G Crespo Rocha4, Camila R Reyes Gómez4, maria de los angeles correa4, Marcos Rosemffet5, Virginia Carrizo Abarza4, Santiago Catalan Pellet6, Miguel Perandones4, Cecilia Reimundes7, Yesica Longueira3, Gabriela Turk3, María Florencia Quiroga3, Natalia Laufer3, Rosana Quintana8, Maria De la Vega9, Nicolás Kreplak10, Marina Pifano10, Pablo Maid2, Guillermo Pons-Estel11 and Gustavo Citera1, 1Instituto de Rehabilitación Psicofísica (IREP), Buenos Aires, Argentina, 2Austral University Hospital, Rheumatology Department, Buenos Aires, Argentina, 3Universidad de Buenos Aires. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones Biomédicas en Retrovirus y Sida (INBIRS). Facultad de Medicina, Buenos Aires, Argentina, 4Rheumatology Unit, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 5Rheumatology Unit, Instituto de Rehabilitación Psicofísica, Capital Federal, Argentina, 6Austral University Hospital, Rheumatology Department, Lincoln, Argentina, 7Austral University Hospital, Rheumatology Department, Pilar, Argentina, 8Centro Regional de Enfermedades Autoinmunes y Reumáticas. Grupo Oroño (GO CREAR) and Research Unit Argentine Society of Rheumatology, Buenos Aires, Argentina, 9Argentine Society of Rheumatology, Buenos Aires, Argentina, 10Ministry of Health of the Province of Buenos Aires, Buenos Aires, Argentina, 11CREAR, Rosario, Argentina

    Background/Purpose: Patients with immune mediated diseases achieve lower seroconversion rates to COVID19 vaccines compared to healthy controls, which is why these patients are a prioritized…
  • Abstract Number: 0838 • ACR Convergence 2022

    Is SARS-CoV-2 Associated with Worse Outcomes After Total Knee Arthroplasty?

    Lisa Mandl1, Benjamin Swett1, Robyn Lipschultz1, Myriam Lin1, Alison Zhao2, Carola Hanreich1, Dongmei Sun1, Kethy Jules-elysee1 and Friedrich Boettner1, 1Hospital for Special Surgery, New York, NY, 2Cleveland Clinic Lerner College of Medicine, Cleveland, OH

    Background/Purpose: Over 520 million people have been infected by SARS-CoV-2. In 10-40%, disabling symptoms such as fatigue and dyspnea can persist. Risk factors for poor…
  • Abstract Number: 1201 • ACR Convergence 2022

    Autoimmune Serologies, Cell-Bound Complement Activation Products, and Autoimmune Rheumatic Disease Symptoms After COVID-19 Infection

    Emily G Oakes1, Jack Ellrodt1, Roberta Alexander2, John Conklin2, May Choi3, Hongshu Guan1, Sara Tedeschi1, Jeffrey Sparks4, Siobhan Case5, Tiffany Hsu1, Daniel Solomon1, Anna Jonsson1 and Karen Costenbader1, 1Brigham and Women's Hospital, Boston, MA, 2Exagen, Inc., Vista, CA, 3Brigham and Women's Hospital | University of Calgary, Calgary, AB, Canada, 4Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 5Brigham and Women's Hospital, Boston Children's Hospital, Boston, MA

    Background/Purpose: Onset of autoimmune connective tissue disease (CTD) after COVID-19 infection has been reported and complement activation has been implicated. We examined common autoimmune rheumatic…
  • Abstract Number: 1591 • ACR Convergence 2022

    Overall and Post-vaccination Prevalence of Severe COVID-19-related Events Among Commercially Insured Patients with Systemic Lupus Erythematosus and the General U.S. Population

    Sandra Sze-jung Wu1, Gelareh Atefi2, Meghan Moynihan3, Kristin Evans3, Liisa Palmer3, Michael Pollack2, Christine Dube4 and Cassandra Calabrese5, 1AstraZeneca, Hockessin, DE, 2AstraZeneca, Wilmington, DE, 3Merative, Cambridge, MA, 4AstraZeneca, Torrington, CT, 5Cleveland Clinic Foundation, Cleveland Heights, OH

    Background/Purpose: To assess the prevalence of severe COVID-19 (COVID) overall and following vaccination among patients with systemic lupus erythematosus (SLE) and the general population, and…
  • Abstract Number: 1875 • ACR Convergence 2022

    Assessment of Antibody Levels to Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) in Patients with Idiopathic Inflammatory Myopathies Receiving Treatment with Intravenous Immunoglobulin

    Sangmee Bae1, emmanuelle Faure-Kumar1, Jennifer Wang2, Ani Shahbazian2, linh Truong2, Howard Yang2, Maureen McMahon1, John FitzGerald1 and Christina Charles-Schoeman3, 1University of California Los Angeles, Los Angeles, CA, 2UCLA Medical Center, Los Angeles, CA, 3Division of Rheumatology, University of California, Los Angeles, Santa Monica, CA

    Background/Purpose: Antibodies to Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) have been reported in pooled donor plasma and intravenous immunoglobulin products (IVIG) since May 2020 (C…
  • Abstract Number: 2186 • ACR Convergence 2022

    Cellular and Humoral Responses Following SARS-CoV-2 mRNA Vaccination in Patients on PD-1 Immunotherapy with irAEs

    Sokratis Apostolidis1, Paulina Coutifaris2, Mark Painter3, Ajinkya Pattekar2, Rishi Goel1, divij mathew2, Wenzhao Meng2, Kevin Wang2, Bria Fulmer2, Angela Corrigan2, Kendall Lundgreen2, Elizabeth Drapeau2, Derek Oldridge2, Josephine Giles2, Amy Baxter2, Sasikanth Manne2, Michelle Mckeague2, Ahron Flowers2, Oliva Kuthuru2, Sherea Long2, Jeanette Dougherty2, Sigrid Gouma2, Justine Williams2, Maura McLaughlin2, Sharon Adamski2, Alba Grifoni4, Daniela Weiskopf4, Alessandro Sette4, Scott Hensley2, Paul Bates2, Eline Luning Prak1, Laura Vella2, Giorgos Karakousis2, Ravi Amaravadi2, Suzanne McGettigan2, Kristin Kreider2, Tara Mitchell2, Allison Greenplate2, Lynn Schuchter2, Alexander Huang2 and E. John Wherry1, 1University of Pennsylvania, Philadelphia, PA, 2UPenn, Philadelphia, 3UPenn, Philadelphia, PA, 4LJI, La Jolla

    Background/Purpose: Patients with cancer exhibit increased mortality from SARS-CoV-2 infection compared to the general population. SARS-CoV-2 mRNA vaccination in healthy individuals generates effective and long-lasting…
  • Abstract Number: 0145 • ACR Convergence 2022

    Vaccination Immune Response Against Sars-Cov-2 in Patients with Autoimmune Rheumatic Diseases

    Paula María Corbalan1, MARIANA PERA1, Ana Lucia Barbaglia2, Maria Constanza Bertolaccini3, Luciana González Lucero4, Raul Sueldo5, Rosana Nieves Chehín6, Rodrigo Hernán Tomas-Grau6, Diego Ploper6, Esteban Vera Pinguitore7, César Luis Ávila7, Benjamín Socías7, Silvia Inés Cazorla8, Carolina Maldonado Galdeano8 and VERONICA BELLOMIO4, 1Hospital Ángel C Padilla, San Miguel de Tucumán, Tucuman, Argentina, 2Hospital Padilla, Tucumán, Argentina, 3Hospital Padilla, San Miguel de Tucuman, Argentina, 4Hospital Padilla, San Miguel de Tucumán, Argentina, 5Hospital Ángel Cruz Padilla, Tucumán, Argentina, 6Instituto de Investigación en Medicina Molecular y Celular Aplicada (IMMCA), San Miguel de Tucumán, Argentina, 7Instituto de Investigación en Medicina Molecular y Celular Aplicada (IMMCA), San Miguel de Tucumán, Tucuman, Argentina, 8Centro de Referencia para Lactobacilos (CERELA), San Miguel de Tucumán, Tucuman, Argentina

    Background/Purpose: Several trials have reported lower seroconversion rates in patients with autoimmune rheumatic diseases than in healthy patients. In Argentina, the vaccines against SARS-CoV-2 that…
  • Abstract Number: 0511 • ACR Convergence 2022

    SARS-CoV-2 mRNA Vaccine Immunogenicity in Chronic Inflammatory Arthritis on DMARD Therapy

    Nedal Darwish1, Sameer Jhaveri2, Uma Yoganathan1, Halima Bakillah1, Kelly Y. Chun3, Thomas Wasser4 and James Freeman1, 1Arnot Ogden Medical Center, Elmira, NY, 2Lake Erie College of Osteopathic Medicine, Elmira, NY, 3Labcorp, Calabasas, CA, 4Consult-Stat, Macungie, PA

    Background/Purpose: Patients with chronic inflammatory arthritis (CIA) are at increased risk for the development and mortality from COVID-19. Vaccinations are integral to the management of…
  • Abstract Number: 0753 • ACR Convergence 2022

    Humoral Immune Response Against BNT162b2 mRNA COVID-19 Vaccine in Patients with Rheumatic Disease Undergoing Immunosuppressive Therapy: A Japanese Monocentric Study

    Koichi Sugihara1, Risa Wakiya1, Tomohiro Kameda1, Hiromi Shimada1, Shusaku nakashima1, Mikiya Kato1, Taichi Miyagi1, mao mizusaki2, Rina Mino1 and Hiroaki Dobashi3, 1Kagawa University, Miki-cho, Kita-gun, Japan, 2Kagawa University, Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Miki-cho, Kita-gun, Japan, 3Division of Hematology, Rheumatology and Respiratory Medicine, Department of Internal Medicine, Faculty of Medicine, Kagawa, Japan

    Background/Purpose: BNT162b2 is the most commonly used COVID-19 vaccine in Japan. The safety and efficacy of the vaccine was demonstrated in the general population, but…
  • Abstract Number: 0787 • ACR Convergence 2022

    Relationship Between Humoral and Cellular Immune Responses in Persons with Rheumatoid Arthritis Following a Third Dose of COVID-19 Vaccine

    Sara Tedeschi1, Daniel Solomon1, Yuezhou Chen2, Jack Ellrodt1, Mary Grace Whelan1, Jacklyn Stratton1, Keigo Hayashi3, Noah Whiteman2, Lin Chen1, Ifeoluwakiisi Adejoorin1, Kathryne Marks1, Emma Gomez-Rivas1, Deepak Rao1, Anna Jonsson1 and Duane Wesemann2, 1Brigham and Women's Hospital, Boston, MA, 2Harvard Medical School, Boston, MA, 3Brigham and Women's Hospital, Okayama, Japan

    Background/Purpose: DMARDs that treat RA may reduce immune responses to COVID-19 vaccination. We compared measures of humoral and cell-mediated immunity in RA patients before and…
  • Abstract Number: 0861 • ACR Convergence 2022

    Incidence of Juvenile Idiopathic Arthritis During the COVID-19 Pandemic: An Analysis of National United States Administrative Claims Data

    Daniel Horton1, Amanda Neikirk2, Yiling Yang2, Cecilia Huang3, Stephen Crystal4, amy davidow5, Kevin Haynes6, Tobias Gerhard7, Carlos Rose8, Brian Strom9 and Lauren Parlett2, 1Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, 2HealthCore, Wilmington, DE, 3Rutgers Center for Pharmacoepidemiology and Treatment Science, New Brunswick, NJ, 4Rutgers Center for Health Services Research, New Brunswick, NJ, 5New York University, New York, NY, 6Johnson & Johnson, Titusville, NJ, 7Ernest Mario School of Pharmacy, Rutgers University, New Brunswick, NJ, 8Nemours, Chadds Ford, PA, 9Rutgers Biomedical and Health Sciences, Newark, NJ

    Background/Purpose: Limited information exists on how rates of diagnosis of rheumatic diseases have changed during the COVID-19 pandemic. We compared rates of JIA diagnosis before…
  • Abstract Number: 1205 • ACR Convergence 2022

    Comparative Effectiveness of BNT162b2 and mRNA-1273 Vaccines Against COVID-19 Infection Among Patients with Systemic Autoimmune Rheumatic Diseases

    Claire Cook1, Naomi Patel2, Xiaoqing Fu1, Xiaosong Wang3, Yumeko Kawano3, Kathleen Vanni3, Grace Qian3, Emily Banasiak3, Emily Kowalski3, Hyon Choi4, yuqing zhang5, Jeffrey Sparks6 and Zachary Wallace1, 1Massachusetts General Hospital, Boston, MA, 2Massachusetts General Hospital, Sale Creek, TN, 3Brigham and Women's Hospital, Boston, MA, 4MASSACHUSETTS GENERAL HOSPITAL, Lexington, MA, 5Massachusetts General Hospital, Quincy, MA, 6Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: Patients with systemic autoimmune rheumatic diseases (SARDs) on immunomodulatory medications may be at particular risk for COVID-19 breakthrough infection given uncertain immune response to…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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