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Abstracts tagged "corticosteroids"

  • Abstract Number: 1523 • ACR Convergence 2023

    The Risk of Scleroderma Renal Crisis from Intraarticular Corticosteroid Injection in Systemic Sclerosis

    Muruganandam Maheswari, Eyerusalem Akpan, Matthew Mcelwee, Meredith Keller, Angie Ariza - Hutchinson, Rosemina Patel, Wilmer Sibbitt, Frank O'Sullivan, Sharon nunez, N. Suzanne Emil and Roderick Fields, University of New Mexico, Albuquerque, NM

    Background/Purpose: Scleroderma renal crisis (SRC) is a rare but a life-threatening complication of systemic sclerosis (SSc), affecting 2-15% of patients with SSc. SRC has been…
  • Abstract Number: 1840 • ACR Convergence 2023

    Value of Various Intra-Articular Injections for Knee Osteoarthritis Management

    Hanna Mass1, Jamie Collins1, david Hunter2, Catherine Yang1, Morgan Jones1, Stephen Messier3, Tuhina Neogi4, A. David Paltiel5, Jeffrey Katz1 and Elena Losina6, 1Brigham and Women's Hospital, Boston, MA, 2Sydney Musculoskeletal Health, University of Sydney, St. Leonards, Australia, 3Wake Forest University, Winston-Salem, NC, 4Boston University School of Medicine, Boston, MA, 5Yale School of Public health, New Haven, CT, 6Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Intra-articular injections (IAI) are commonly used to relieve pain and delay total knee replacement (TKR) in persons with knee OA. Despite higher costs and…
  • Abstract Number: 1988 • ACR Convergence 2023

    Extended-Release versus Immediate-Release Triamcinolone Acetonide for Osteoarthritis of the Knee with Comorbid Diabetes Type 2 Diabetes Mellitus: A Post Hoc Analysis

    Andrew Spitzer1, Helena Rodbard2, Sheikh Usman Iqbal3, Masato Nakazawa3, Mary DiGiorgi3 and Roy Winston3, 1Cedars-Sinai Medical Center, Los Angeles, CA, 2Endocrine and Metabolic Consultants, Rockville, MD, 3Pacira BioSciences, Inc., Tampa, FL

    Background/Purpose: Intraarticular (IA) corticosteroids are generally considered safe and effective to treat osteoarthritis of the knee (OAK) but may cause hyperglycemia that may last for…
  • Abstract Number: 2307 • ACR Convergence 2023

    Comparing Social Vulnerability Index to Area Deprivation Index to Patient Outcomes in SLE and Glucocorticoid Utilization

    Avira Som1, Lily McMorrow1, Ling Chen1, Deepali Sen2, Elizabeth Baker3 and Alfred Kim4, 1Washington University School of Medicine in St. Louis, St. Louis, MO, 2Washington University in St. Louis, St. Louis, MO, 3Saint Louis University, St. Louis, MO, 4Washington University School of Medicine, St. Louis, MO

    Background/Purpose: As shown in previous studies, outcomes in SLE are affected by social determinants of health which influence health care disparities. Evaluating health disparities through…
  • Abstract Number: 2498 • ACR Convergence 2023

    Does Physical Activity Modify the Relationship Between Pain and Corticosteroid Injection Utilization in Adults with or at High Risk for Knee Osteoarthritis?

    Sydney Liles1, Daniel White2, Thomas Bye2 and Jason Jakiela2, 1University of Delaware, Elkton, MD, 2University of Delaware, Newark, DE

    Background/Purpose: Knee osteoarthritis (OA) is a leading global cause of pain and disability, with no current cure. Knee pain is the most common symptom and…
  • Abstract Number: 024 • 2023 Pediatric Rheumatology Symposium

    Effects of Corticosteroids on Central Nervous System Microvascular Properties Assessed by Neuroimaging

    Mark DiFrancesco, Ekemini Ogbu, Catherine Robben, Jennifer Huggins and Hermine Brunner, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose: Prior research suggests that microvascular (MV) changes might be a biomarker for central nervous system (CNS) involvement of patients with systemic lupus erythematosus (SLE).…
  • Abstract Number: 028 • 2023 Pediatric Rheumatology Symposium

    Achieving Medication-Free Remission in Juvenile Dermatomyositis

    Harneet Ghumman1, Ilaria Maccora2, Hermine Brunner1, Amy Cassedy3, Mekibib Altaye2, Asra Firdous1, Alexei Grom1, Daniel Lovell1, Angela Merritt1, Megan Quinlan-Waters1 and Sheila Angeles-Han2, 1Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Cincinnati Children's Hospital, Cincinnati, OH, 3Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose: Juvenile dermatomyositis (JDM) is characterized by symmetric proximal muscle weakness, distinct rash, and a risk for calcinosis. Systemic immunosuppression is needed. Evidence is limited…
  • Abstract Number: L17 • ACR Convergence 2022

    Evaluating the Safety and Factors Associated with Treatment Cessation in Takayasu Arteritis

    Robert Maughan1, Andrew Porter1, Chanaka Dahanayake2, Claudia Ianonne1, Ritu Alapat1, Charis Pericleous1, Taryn Youngstein3 and Justin Mason1, 1Imperial College London, London, United Kingdom, 2Barts Health NHS Trust, London, United Kingdom, 3Imperial NHS Trust, London, United Kingdom

    Background/Purpose: Immunosuppression in Takayasu Arteritis (TA) reduces the risk of arterial damage and disease progression. However, long-term use of glucocorticoids (GC) and other immunosuppressants carries…
  • Abstract Number: 0539 • ACR Convergence 2022

    Cardiac Complications, Thrombosis, Infections and All-cause Mortality Among Patients with End-Stage Kidney Disease Due to Lupus Nephritis in the USRDS 2006-2013 According to SLE Medication Use

    Anna Broder1, Wenzhu B. Mowrey2, Kazuki Yoshida3 and Karen Costenbader3, 1Hackensack University Medical Center, Hackensack, NJ, 2Albert Einstein College of Medicine, Bronx, NY, 3Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Medication management strategies in patients with lupus-related end stage kidney disease (ESKD) have not been studied. Our prior work has shown that HCQ may…
  • Abstract Number: 0590 • ACR Convergence 2022

    Molecular Profiling of Normal Human Synovium Reveals Striking Impact of Adipocytes and Homeostatic Cortisol Signaling

    Heather Faust1, Tan-Yun Cheng1, Ilya Korsunsky1, Gerald FM Watts1, David Moody1 and Michael Brenner2, 1Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: The synovium encapsulates joints and contains fibroblasts which proliferate, become invasive, and drive disease progression in rheumatoid arthritis (RA) and osteoarthritis (OA). There is…
  • Abstract Number: 0621 • ACR Convergence 2022

    Altered Immunological Circadian Rhythms and the Effect of Treatment with Glucocorticoids on Circadian Rhythms of Immune Cells in Patients with Rheumatoid Arthritis: Bring Back the Rhythm

    Siska Wilantri1, Cindy Strehl1, Dimas Abdirama1, Timo Gaber1, Robert Biesen2 and Frank Buttgereit1, 1Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin / DRFZ Berlin, Berlin, Germany, 2Charité Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany

    Background/Purpose: Clinical symptoms of rheumatoid arthritis (RA), including pain, joint stiffness, and swelling, exhibit a distinct circadian rhythm that exacerbates in the early morning in…
  • Abstract Number: 0767 • ACR Convergence 2022

    Canadian Research Group of Rheumatology in Immuno-Oncology (CanRIO) – A Retrospective Chart Review Study of Adults with Inflammatory Arthritis Associated with Cancer Immunotherapies

    Megan Himmel, Alexandra Saltman and Brooke Pollock, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Cancer therapies that target immune checkpoints have gained a prominent role in the treatment of malignancy. These agents stimulate an impressive and sustained anti-tumour…
  • Abstract Number: 0866 • ACR Convergence 2022

    Outcomes of Children with Uveitis Associated with Autosomal Dominant Neovascular Inflammatory Vitreoretinopathy (ADNIV) Treated with Methotrexate and Infliximab

    Sheila Angeles-Han1, Grant Schulert1, Megan Quinlan-Waters1, Alexandra Duell1, Jennifer Huggins1, Tiffany Nguyen2, Cameron Sapp2, Sumit Sharma3, Sunil Srivastava4 and Arjun Sood2, 1Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Cincinnati Eye Institute, Cincinnati, OH, 3Cole Eye Institute, Cleveland Clinic, Cleveland, OH, 4Cole Eye Institute, Cleveland Clinic, Cincinnati, OH

    Background/Purpose: Pediatric uveitis is commonly associated with rheumatic disease and can lead to sight-threatening complications. Initial treatment are glucocorticoids and subsequently methotrexate (MTX) and TNF…
  • Abstract Number: 1106 • ACR Convergence 2022

    Effect of Tocilizumab on Disease Activity in Patients with Active Polymyalgia Rheumatica on Glucocorticoid Therapy: A Randomized Clinical Trial

    Valerie Devauchelle1, Guillermo CARVAJAL ALEGRIA2, Emmanuelle Dernis3, Christophe Richez4, Marie Truchetet5, Daniel Wendling6, ERIC TOUSSIROT7, aleth Perdriger8, jacques-eric gottenberg9, Renaud FELTEN10, Bruno Fautrel11, laurent chiche12, Pascal HILLIQUIN13, Catherine Le Henaff14, Benjamin Dervieux15, Guillaume Direz16, Isabelle Chary-Valckenaere17, Divi CORNEC18, Dewi Guellec19, Thierry MARHADOUR20, Emmanule Nowak19 and Alain Saraux21, 1Université de Bretagne Occidentale, Brest, France, 2CHRU de Tours, Tours, France, 3LE MANS general hospital, LE MANS, France, 4Université de Bordeaux, Bordeaux, France, 5Bordeaux University Hospital, Bordeaux, France, 6CHU, University Teaching Hospital, Besançon, France, 7CHU de Besançon, Besançon, France, 8Rennes University, Rennes, France, 9Strasbourg University Hospital, Strasbourg, France, 10Hôpitaux Universitaires de Strasbourg, Strasbourg, France, 11Sorbonne University Paris, France and Pierre Louis Institute of Epidemiology and Public Health, Paris, France, Paris, France, 12hopital europeen, Marseille, France, 13Centre Hospitalier Sud-Francilien, Corbeil-Essonnes, France, 14Morlaix Hospital, Morlaix, France, 15Mulhouse Hospital, Mulhouse, France, 16Le Mans Hospital, Le Mans, France, 17Nancy University Hospital, Vandoeuvre, France, 18CHRU Brest, Brest, France, 19Brest University Hospital, Brest, France, 20CHU Cavale Blanche, Brest, France, 21CHU Brest, Brest, France

    Background/Purpose: Few treatments are available for patients with glucocorticoid-dependent polymyalgia rheumatica (PMR). Interleukin-6 antagonists deserve evaluation in active glucocorticoid-dependent PMR. Our objective was to compare…
  • Abstract Number: 1549 • ACR Convergence 2022

    Toward Safer Glucocorticoid Therapy

    Xingyu Pan1, Qiongqiong Hou1, Jiahui Xu1, Yake Ma1, Jiawen Li1, Min Li1, Jing Su1, Xuerou Shi1, William Bracken2 and David Katz2, 1WuXi AppTec, Nantong, China, 2Sparrow Pharmaceuticals, Portland, OR

    Background/Purpose: SPI-62 is a potent 11b-hydroxysteroid dehydrogenase type 1 (HSD-1) inhibitor entering Phase 2 development as adjunctive therapy to prednisolone in polymyalgia rheumatica, as well…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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