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Abstracts tagged "corticosteroids"

  • Abstract Number: 0153 • ACR Convergence 2021

    Echogenic and Hypervascular Synovium Detected on Ultrasound Are Predictive of a Favorable Response After Intra-articular Corticosteroid Injection in Patients with Knee Osteoarthritis

    Robert Dima1, Trevor Birmingham2, Ryan Pinto3, Holly Philpott1, McKenzie Carter1 and Tom Appleton2, 1Western University, London, ON, Canada, 2University of Western Ontario, London, ON, Canada, 3Western University, Kitchener, ON, Canada

    Background/Purpose: Intra-articular corticosteroids (IACS) are commonly used for symptom management in knee osteoarthritis (KOA) patients, despite the fact that many patients do not respond to…
  • Abstract Number: 0492 • ACR Convergence 2021

    Racial Differences in Glucocorticoid Use Among Medicaid Beneficiaries with Incident Systemic Lupus Erythematosus

    Mia Chandler1, Leah Santacroce2, Karen Costenbader3, Rishi Desai4, Seoyoung Kim2 and Candace Feldman2, 1Boston Children's Hospital, Brookline, MA, 2Brigham and Women's Hospital, Boston, MA, 3Brigham and Women's Hospital, Belmont, MA, 4Brigham and Women's Hospital/Harvard Medical School, Boston, MA

    Background/Purpose: Glucocorticoids (GCs) are an integral part of systemic lupus erythematosus (SLE) treatment. Long-term use of GCs is associated with adverse effects. This study evaluated…
  • Abstract Number: 0730 • ACR Convergence 2021

    Safety, Tolerability, and Pharmacokinetics of an Intra-articular Corticosteroid Injection Administered 7 Days Before or After Intra-articular Lorecivivint Injection into the Same Knee of Healthy Volunteers: An Open-Label, Parallel-Arm Study

    Amy Halseth1, Nancy Lane2, Sarah Kennedy3, Christopher Swearingen1, Victor Lopez1, Ismail Simsek1, Mark Fineman1 and Yusuf Yazici4, 1Biosplice Therapeutics, Inc., San Diego, CA, 2University of California Davis, Hillsborough, CA, 3Biosplice Therapeutics, Inc, San Diego, CA, 4New York University School of Medicine, La Jolla, CA

    Background/Purpose: Knee osteoarthritis (OA) is a painful condition leading to joint damage and impaired function. Intra-articular (IA) corticosteroid injections are frequently prescribed to treat pain.…
  • Abstract Number: 1116 • ACR Convergence 2021

    Disease Characteristics of Steroid-Induced Spinal Epidural Lipomatosis: A Systematic Review

    Haseeb Chaudhary1, Usama Nasir2, Khezar Syed3, Abigayle Sullivan3, Shilla Zachariah3, Christian AkemDimala3, Muhammad Khan4 and Anthony Donato3, 1Tower Health System, Reading, PA, 2Reading Hospital, Tower Health System, Reading, PA, 3Reading Hospital, Tower Health System, Reading, PA, 4University of Kentucky, Lexington, KY

    Background/Purpose: Steroid-induced epidural lipomatosis (SEL) is a rare phenomenon causing neuronal compression from adipose tissue deposition in the epidural space. We analyzed the available literature…
  • Abstract Number: 1242 • ACR Convergence 2021

    Sex Differences in Treatment Response to Three Different Biological Treatments and Corticosteroids in Patients with Early Rheumatoid Arthritis

    Kristina Lend1, Ronald F van Vollenhoven2, Jon Lampa3, Merete Hetland4, Espen Haavardsholm5, Dan Nordström6, Michael Nurmohamed7, Bjorn Gudbjornsson8, Anna Rudin9, Mikkel Ostergaard10, Till Uhlig11, Gerdur Grondal8, Kim Hørslev-Petersen12, Marte S Heiberg5, Tuulikki Sokka-Isler13, Jos Twisk14 and Irene van der Horst-Bruinsma15, 1Department of Medicine, Rheumatology Unit, The Karolinska Institute, Stockholm, Sweden, 2Amsterdam University Medical Centers, Department of Rheumatology and Clinical Immunology, Rheumatology and Immunology Center ARC, Amsterdam, Netherlands, 3Karolinska University Hospital, Department of Medicine, Rheumatology Unit, The Karolinska Institute, Stockholm, Sweden, Stockholm, Sweden, 4DANBIO and COPECARE, Centre for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, 5Diakonhjemmet Hospital, Oslo, Norway, 6Division of Internal Medicine and Rheumatology, Helsinki University Hospital, Helsinki, Finland, 7Amsterdam University Medical Centers, Amsterdam Rheumatology and Immunology Center, Amsterdam, Netherlands, 8Landspitali University Hospital, University of Iceland, Reykjavik, Iceland, 9Rheumatology Clinic, Sahlgrenska University Hospital, Sahlgrenska Academy of University of Gothenburg, Gothenburg, Sweden, 10Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, and Department of Clinical Medicine, University of Copenhagen, Glostrup, Denmark, 11Diakonhjemmet Hospital, University of Oslo, Oslo, Norway, 12Danish Hospital for Rheumatic Diseases, University of Southern Denmark, Reykjavik, Iceland, Haderslev, Denmark, 13University of Eastern Finland, Jyväskylä Central Hospital, Jyväskylä, Finland, 14Department of Epidemiology and Biostatistics, Amsterdam University Medical Centres, Amsterdam, Netherlands, 15Department of Rheumatology, VU University Medical Centre, Amsterdam, Netherlands

    Background/Purpose: To investigate sex differences in clinical response to three different biological treatments in combination with methotrexate (MTX) versus MTX plus corticosteroids (active conventional treatment;…
  • Abstract Number: 1264 • ACR Convergence 2021

    Racial Differences in Chronic Glucocorticoid Use in Patients with SLE: A Cross Sectional Study

    James Sullivan1 and Emily Littlejohn2, 1Cleveland Clinic Lerner College of Medicine, Cleveland Heights, OH, 2Cleveland Clinic, Cleveland, OH

    Background/Purpose: Black patients with systemic lupus erythematosus (SLE) face higher rates of morbidity and mortality compared to White patients. Long-term glucocorticoid use has been associated…
  • Abstract Number: 1408 • ACR Convergence 2021

    Treatment of Giant Cell Arteritis in the ARTESER Multicenter Study of 1675 Patients

    Jesús T. Sánchez-Costa1, Iñigo Hernández-Rodríguez2, Elisa Fernández-Fernández3, María T. Silva-Diaz4, Jesús A. Valero-Jaimes5, Ismael González-Fernández6, Julio Sánchez7, Judit Lluch8, Eva Galindez-Agirregoikoa9, Javier Mendizábal-Mateos10, Pia M. Lois Bermejo11, Javier Loricera12, Alejandro Muñoz13, Cristina Valero-Martínez14, Patricia Moya15, Carmen Larena-Grijalba16, Vanessa A. Navarro-Angeles17, Joan Calvet-Fontova18, Ivette Casafont19, Francisco Ortiz-Sanjuán20, Selene Labrada-Arrabal21, Jaime Calvo-Alén22, Carlota L. Iñiguez-Ubiaga23, Vanesa Hernández24, Cristina Campos-Fernández25, María Alcalde-Villar26, Antonio Juan-Mas27, Eugenio De Miguel28, Javier Narvaez29, Miguel Ángel gonzalez-Gay30, Noemí Garrido-Puñal31, Paula V. Estrada-Alarcon17 and Ricardo Blanco32, 1Spanish Society of Rheumatology, Madrid, Spain, 2Complejo Hospitalario Universitario de Vigo, Vigo, Spain, 3Rheumatology department, La Paz University Hospital, Madrid, Spain, 4Complejo Hospitalario Universitario de La Coruña, Coruña, Spain, 5Hospital Universitario Donostia, Donostia-San Sebasti, Spain, 6Hospital Universitario de León, León, Spain, 7Hospital Universitario 12 de Octubre, Madrid, Spain, 8Hospital Universitari Bellvitge, Hospitalet de Llobregat, Spain, 9Hospital Universitario de Basurto, Bilbao, Spain, 10H. Navarra, Navarra, Spain, 11Rheumatology Department, Hospital Clínico San Carlos, Madrid, Spain, 12Hospital Universitario Marqués de Valdecilla, Santander, Spain, 13Hospital Universitario Virgen del Rocío, Sevial, Spain, 14Hospital Universitario de La Princesa, Madrid, Spain, 15Hospital Sant Pau, Barcelona, Spain, 16Rheumatology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain, 17Hospital de Sant Joan Despí Moisès Broggi. Sant Joan Despí, Barcelona, Spain, 18Hospital Universitari Parc Tauli, Sabadell, Spain, 19Hospital Universitari Germans Trias i Pujol, Barcelona, Badalona, Spain, 20H. La Fe, Valencia, Spain, 21Hospital del Mar, Barcelona, Spain, 22Rheumatology Department, Hospital Universitario Araba, Vitoria-Gasteiz, Spain, 23Hospital Universitario Lucus Augusti, Lugo, Spain, 24Rheumatology Department, Hospital Universitario de Canarias, La Laguna, Spain, 25Consorci Hospital General Universitari de Valencia, Valencia, Spain, 26Hospital Universitario Severo Ochoa, Leganés, Spain, 27Hospital Universitario Son Llàtzer, Palma de Mallorca, Spain, 28Hospital Universitario La Paz, Madrid, Spain, 29Division of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 30Research group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic Bone Diseases of the Musculoskeletal System, IDIVAL, Division of Rheumatology, Hospital Universitario Marqués de Valdecilla; School of Medicine, Universidad de Cantabria, Santander, Spain. Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, 31Hospital Universitario Virgen del Rocío, Sevilla, Spain, 32Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain

    Background/Purpose: Glucocorticoids (GC) are the mainstay therapy in Giant Cell Arteritis (GCA), initially at high doses (40-60 mg/day) followed by gradual glucocorticoid tapering. This treatment,…
  • Abstract Number: 1461 • ACR Convergence 2021

    Belimumab Improves Renal Responses in Patients with or Without Steroid Pulses During Induction Therapy for Lupus Nephritis

    Richard Furie1, Frédéric Houssiau2, Liz Lightstone3, Xueqing Yu4, Julia Weinmann-Menke5, Yoshiya Tanaka6, Angela Jones-Leone7, Tania Gonzalez-Rivera7, Jennifer Gilbride8, Anuradha Madan7, Yulia Green8 and David Roth7, 1Zucker School of Medicine at Hofstra/Northwell, Great Neck, NY, 2Cliniques Universitaires Saint-Luc, UCLouvain, Brussels, Belgium, 3Department of Immunology and Inflammation, Imperial College, London, United Kingdom, 4Guangdong Provincial People’s Hospital and Guangdong Academy of Medical Sciences, Guangzhou, China (People's Republic), 5University Hospital Mainz, Mainz, Germany, 6University of Occupational and Environmental Health, Kitakyushu, Japan, 7GlaxoSmithKline, Collegeville, PA, 8GlaxoSmithKline, Brentford, United Kingdom

    Background/Purpose: In the BLISS-LN trial (GSK Study BEL114054; NCT01639339), the administration of belimumab (BEL), a B-lymphocyte stimulator antagonist, resulted in improved renal outcomes in patients…
  • Abstract Number: 1642 • ACR Convergence 2021

    Baseline Body-mass-index and Risk for Obesity in Children with Rheumatic Disease on Moderate to High-dose Prednisone Therapy

    Roberta Berard1, Michael Rieder2, Erkan Demirkaya2, Michael Miller3 and Renee Pang2, 1London Health Sciences Centre, London, ON, Canada, 2University of Western Ontario, London, ON, Canada, 3University of Western Ontario, Children's Research Institute, London, ON, Canada

    Background/Purpose: Prednisone is a glucocorticoid (GC) medication commonly used in moderate ( >7.5 mg per day) to high doses (≥ 1 mg/kg/day) for children with…
  • Abstract Number: 1678 • ACR Convergence 2021

    Favorable Balance of Benefit and Harm of Long-Term, Low Dose Prednisolone Added to Standard Treatment in Rheumatoid Arthritis Patients Aged 65+: The Pragmatic, Multicenter, Placebo-Controlled GLORIA Trial

    Maarten Boers1, Linda Hartman1, Daniela Opris-Belinski2, Reinhard Bos3, Marc Kok4, Jose Pereira da Silva5, Ed Griep6, Ruth Klaasen7, Cornelia F. Allaart8, Paul Baudoin9, Hennie Raterman10, Zoltan Szekanecz11, Frank Buttgereit12, Pavol Masaryk13, L. Thomas Klausch1, Sabrina Paolino14, Annemarie Schilder3, Willem Lems15 and Maurizio Cutolo14, 1Amsterdam UMC, Vrije Universiteit, Amsterdam, Netherlands, 2Carol Davila University, Bucharest, Romania, 3Medical Center Leeuwarden, Leeuwarden, Netherlands, 4Maasstad Hospital, Rotterdam, Netherlands, 5University of Coimbra | UC · Clínica Universitária de Reumatologia. Faculty of Medicine, Columbia, Portugal, 6Antonius Hospital, Sneek, Netherlands, 7Meander Medical Center, Amersfoort, Netherlands, 8Leiden University Medical Center, Leiden, Netherlands, 9Reumazorg Flevoland, Emmeloord, Netherlands, 10Northwest Clinics, Alkmaar, Netherlands, 11Division of Rheumatology, University of Debrecen, Faculty of Medicine, Debrecen, Hungary, 12Charité – Universitätsmedizin Berlin, Berlin, Germany, 13National Institute for the Rheumatic Diseases, Bratislava, Slovakia, 14Laboratory of Experimental Rheumatology and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS Polyclinic San Martino Hospital, Genoa, Italy, 15VUmc, Amsterdam, Netherlands

    Background/Purpose: Low-dose glucocorticoid (GC) therapy is widely used in rheumatoid arthritis (RA) but the balance of benefit and harm is still unclear. We studied the…
  • Abstract Number: 1735 • ACR Convergence 2021

    Glucocorticoid Discontinuation in Patients with Systemic Lupus Erythematosus with Prior Severe Organ Manifestation

    Takehiro Nakai1, Futoshi Iwata1, Genki Kidoguchi1, Sho Fukui2, Hiroki Ozawa1, Satoshi Kawaai3, Yukihiko Ikeda1, Ayako Koido4, Masei Suda5, Atsushi Nomura6, Hiromichi Tamaki1, Kenichi YAMAGUCHI1 and Masato Okada1, 1St. Luke's International Hospital, Tokyo, Japan, 2Immuno-Rheumatology Center, St. Luke’s International Hospital, and Center for clinical epidemiology, St. Luke’s International University, Tokyo, Japan, 3Immuno-Rheumatology Center, St. Luke’s International Hospital, Tokyo, Japan, Chuo-ku, Tokyo, Japan, 4St. Luke's International Hospital, Akashi-cho, Chuo-ku, Tokyo, Japan, 5Suwa Central Hospital, Nagano, Japan, 6St. Luke's International Hospital, Nagareyama, Japan

    Background/Purpose: Most long-term damage in systemic lupus erythematosus (SLE) has been attributed to continuous glucocorticoid use; however, glucocorticoid discontinuation is occasionally associated with disease flare-ups.…
  • Abstract Number: 1914 • ACR Convergence 2021

    Immunomodulatory and Immunosuppressive Medication Modification Among Rheumatology Patients at the Time of COVID-19 Vaccination

    Jonah Levine1, Deanna Jannat-Khah1, Vivian Bykerk2, Lisa Mandl1 and Medha Barbhaiya1, 1Hospital for Special Surgery, New York, NY, 2Division of Rheumatology, Hospital for Special Surgery, New York City, NY

    Background/Purpose: Due to concerns about underlying immune dysregulation and immunosuppression, patients with systemic rheumatic diseases (SRD) may have modified their medications at the time of…
  • Abstract Number: 0058 • ACR Convergence 2021

    Effect of Anti-inflammatory Drugs on Intestinal Epithelial Damage and Bacterial Translocation in the Adjuvant-induced Arthritis Model

    Sophie Hecquet1, Perle Totoson2, Maude Tournier2, Clement Prati1, Daniel Wendling1, Céline Demougeot2 and Frank Verhoeven1, 1Service de rhumatologie, CHU de Besançon, Besançon, France, 2PEPITE EA4267, FHU INCREASE, Bourgogne Franche-Comté University, Besançon, France

    Background/Purpose: The intestine is no longer considered as an organ targeted by spondyloarthritis (SpA) but also an actor of the disease alongside environmental and immunological…
  • Abstract Number: 0111 • ACR Convergence 2020

    Assessment and Treatment of Glucocorticoid-Induced Osteoporosis in a Rheumatology Clinic

    Amanda Stefl1, Shikha Singla2, Jessica Michaud1, Kama Thomas2, Lisa Rein2 and Mary Ellen Csuka2, 1Froedtert Hospital, Milwaukee, WI, 2Medical College of Wisconsin, Milwaukee, WI

    Background/Purpose: Glucocorticoids (GC) are used as a long-term treatment option for an estimated 1% of the US population. The American College of Rheumatology has maintained…
  • Abstract Number: 0113 • ACR Convergence 2020

    Improving Glucocorticoid-Induced Osteoporosis Screening and Management in Patients with Rheumatic Diseases Using the 2017 ACR Guidelines

    Marielys Figueroa Sierra1, Atefeh Vafa1, Shu Cao2, Yuanyuan Lu3, Helen Bateman4, John Carter1, Yih Chang Lin2, Raquel Cuchacovich1, Marcos Maldonado4, Joanne Valeriano-Marcet1 and Gabriela Montes-Rivera4, 1University of South Florida, Tampa, FL, 2University of South Florida, Morsani College of Medicine, Tampa, FL, 3Biostatistician at Graduate Medical Education Department, Tampa, FL, 4James A. Haley VA, Tampa, FL

    Background/Purpose: Glucocorticoid-induced osteoporosis (GIOP) is a potentially preventable complication in those who are maintained on glucocorticoid (GC) therapy.  It is imperative to identify these patients…
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ACR Pediatric Rheumatology Symposium 2020

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