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Abstracts tagged "corticosteroids"

  • Abstract Number: LB16 • ACR Convergence 2025

    Mepolizumab Reduces End-Organ Manifestations Compared with Standard of Care in Patients with EGPA and HES: A US Real-world Analysis

    David Silverman1, Timothy Barnes2, Nnaemeka Odo2, Jared Silver3, Lisa Le2, Amy Edgecomb4 and Hitesh Patel5, 1Rheumatology Department, Kaiser Permanente Colorado Medical Group, Denver, Colorado, 2Value and Evidence Solutions, Optum Life Sciences, Eden Prairie, Minnesota, 3Clinical Development, Amgen, Thousand Oaks, California, 4Anti-infectives and Respiratory, GSK, Philadelphia, Pennsylvania, 5US Medical Affairs, GSK, Durham, North Carolina

    Background/Purpose: Eosinophilic granulomatosis with polyangiitis (EGPA) and hypereosinophilic syndrome (HES) are rare systemic diseases characterized by persistent eosinophilia and tissue infiltration, resulting in end-organ dysfunction…
  • Abstract Number: 2157 • ACR Convergence 2025

    Optimizing the Diagnosis and Treatment of Kawasaki Disease-Associated Macrophage Activation Syndrome: A Clinical Cohort and Literature Analysis

    Xi Yang1, Yuanhao Zhao2, Zhihan Tang2, Haixia Liu2 and Xuemei Tang2, 1Department of Rheumatology & Immunology, Children’s Hospital of Chongqing Medical University, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, National Clinical Research Center for Child Health and Disorders (Chongqing), Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Infection and Immunity, Chongqing, China., Chongqing, China (People's Republic), 2Department of Rheumatology and Immunology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Child Rare Diseases in Infection and Immunity, Chongqing, China, Chongqing, China (People's Republic)

    Background/Purpose: Through a single-center retrospective cohort study and systematic literature review, we aimed to evaluate the applicability of current diagnostic criteria (HLH-2004/2009 and 2016 sJIA-MAS)…
  • Abstract Number: 0420 • ACR Convergence 2025

    Long-term efficacy of intra-articular triamcinolone hexacetonide injections in juvenile idiopathic arthritis patients starting tumor necrosis factor inhibitor therapy: 48 weeks results from a randomized, open-label, blinded-assessor multicenter phase 4 trial – the MyJIA trial

    Pernille Büyesen1, Anna-Birgitte Aga1, Vibke Lilleby1, Maiju Pesonen1, Marite Rygg2, Ellen Nordal3, Bjørn Barstad4, Karin Tylleskär5, Helga Sanner1, Siri Hetlevik1, Nina Martine Sande1, Inge Christoffer Olsen1, Siri Lillegraven6, Espen Haavardsholm7, Athimalaipet Ramanan8, Oyvind Molberg9 and Berit Flatø1, 1Oslo University Hospital, Oslo, Norway, 2Department of Clinical and Molecular Medicine, NTNU - Norwegian University of Science and Technology and Department of Pediatrics, St. Olavs Hospital, Trondheim, Norway., Trondheim, Norway, 3University Hospital of North Norway, Tromsø, Nepal, 4Stavanger University Hospital, Stavanger, Norway, 5Haukeland University Hospital, Bergen, Norway, 6Diakonhjemmet Hospital, Oslo, Norway, 7Center for treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, 8Bristol Royal Hosp for Children, Bristol, United Kingdom, 9Oslo University Hospital, Oslo, Nepal

    Background/Purpose: Modern therapies have improved outcomes in patients with JIA, but up to 60% of patients treated with TNF-α inhibitors (TNFi) have persisting disease activity…
  • Abstract Number: 2098 • ACR Convergence 2025

    Responder Phenotype Analysis for Intra-Articular Injections: Secondary Analysis from a Large Multi-Site Crossover Clinical Trial

    Natalie Keller1, Bryant England2, Katherine Wysham3, Mercedes Quinones4, Marianna Olave5, Sarah Wetzel6, Hannah Brubeck7, Rachel Gillcrist6, Criswell Lavery8, Bibiana Ateh9, Bridget Kramer2, Kimberly Hayes6, Rui Xiao8, Kaitian Jin8, Alexis Ogdie8, Daniel K. White10, Tuhina Neogi11, Carla Scanzello12 and Joshua Baker8, 1University of Oklahoma, Philadelphia, PA, 2University of Nebraska Medical Center, Omaha, NE, 3VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, WA, 4Howard University Hospital and Washington DC Veterans Affairs Medical Center, Washington, District of Columbia, 5Brown University, Philadelphia, PA, 6Corporal Michael J. Crescenz VA Medical Center, Philadelphia, 7VA Puget Sound Health Care System, Seattle, WA, 8University of Pennsylvania, Philadelphia, PA, 9Washington VA Medical Center, Washington, District of Columbia, 10University of Delaware, Newark, DE, 11Boston University School of Medicine, Boston, MA, 12University of Pennsylvania, Philadelphia

    Background/Purpose: Intra-articular (IA) corticosteroid injections are commonly utilized for pain management in knee osteoarthritis (KOA). However, clinical characteristics associated with a greater benefit from corticosteroid…
  • Abstract Number: 0413 • ACR Convergence 2025

    Improving Access to Timely Joint Injections for Pediatric Rheumatology Patients – A Quality Improvement Initiative

    Kendra Lauer1, Vidya Sivaraman2, Melissa Argraves3, Ysabella Esteban4, Laura Pratt5, Alysha Taxter6, Shoghik Akoghlanian3, Kelly Wise7, Kathryn Anliker3, Jonnie Hughes3, James Booker3, Ashlee Leone3 and Edward Oberle3, 1Nationwide Children's Hospital, Dublin, OH, 2Nationwide Children's Hospital/ The Ohio State University, Columbus, OH, 3Nationwide Children's Hospital, Columbus, OH, 4Nationwide Children's Hospital, Plain City, OH, 5Nationwide Children's Hospital/The Ohio State University College of Medicine, Columbus, OH, 6Nationwide Children's, Columbus, OH, 7Nationwide Children's Hospital, Hilliard, OH

    Background/Purpose: Timely treatment for juvenile idiopathic arthritis (JIA) is essential for disease remission and decreasing risk of long-term morbidity. Intra-articular corticosteroid joint injections can treat…
  • Abstract Number: 2096 • ACR Convergence 2025

    Gamification and Social Incentivization to Promote Physical Activity in Adults with Knee Osteoarthritis: Results from a Multi-Site Randomized Trial

    Kimberly Hayes1, Bryant England2, Katherine Wysham3, Mercedes Quinones4, Marianna Olave5, Sarah Wetzel6, Hannah Brubeck7, Rachel Gillcrist8, Criswell Lavery9, Natalie Keller10, Bibiana Ateh11, Bridget Kramer2, Rui Xiao9, Kaitian Jin9, Alexis Ogdie12, Daniel K. White13, Tuhina Neogi14, Carla Scanzello9 and Joshua Baker9, 1Teachers College, Columbia University, Philadelphia, PA, 2University of Nebraska Medical Center, Omaha, NE, 3VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, WA, 4Washington DC VA Medical Center, Bethesda, MD, 5Brown University, Philadelphia, PA, 6Drexel University, Pittsburgh, PA, 7VA Puget Sound Health Care System, Seattle, WA, 8Dartmouth College, Lebanon, NH, 9University of Pennsylvania, Philadelphia, PA, 10University of Oklahoma, Philadelphia, PA, 11Washington VA Medical Center, Washington, District of Columbia, 12Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Wilmington, DE, 13University of Delaware, Newark, DE, 14Boston University School of Medicine, Boston, MA

    Background/Purpose: Promotion of physical activity is important in the management of knee osteoarthritis (KOA), though effective strategies for behavioral change to promote exercise are lacking.…
  • Abstract Number: 0201 • ACR Convergence 2025

    Real-World study of immunogenicity and safety of the adjuvant recombinant vaccine against varicella zoster virus in patients with immune-mediated inflammatory diseases treated with Janus Kinase Inhibitors in comparison with healthy individuals

    Ana Victoria Esteban Vázquez1, Martina Steiner2, Cristina Vergara2, Elisabet Castañeda Estévez3, Maria Beatriz Paredes Romero4, Isabel De La Camara-Fernandez1, Laura Trives1, Tatiana Cobo1, Patricia Richi5, Maria liz Romero5, Marta De San Segundo3, Antonio Sanchis3, Carolina Marín6, Maria Teresa Navio Marco7 and Santiago Muñoz1, 1Hospital Universitario Infanta Sofía;Universidad Europea de Madrid. Faculty of Medicine, Health and Sports. Department of Medicine; FIIB HUIS-HUHEN, Madrid, Spain, 2Hospital Universitario Infanta Sofía;Universidad Europea de Madrid. Faculty of Medicine, Health and Sports. Department of Medicine; FIIB HUIS-HUHEN, Madrid, Madrid, Spain, 3Hospital Universitario Infanta Sofía, Madrid, Spain, 4Infanta Sofía University Hospital, Madrid, Spain, 5Hospital Universitario Infanta Sofía;Universidad Europea de Madrid. Faculty of Medicine, Health and Sports. Department of Medicine; FIIB HUIS-HUHEN, San Sebastian de Los Reyes, Madrid, Spain, 6Department of Rheumatology, Hospital Universitario Infanta Leonor / Universidad Complutense de Madrid, Madrid, Spain, Madrid, Spain, 7Infanta Leonor Universitary Hospital, Madrid, Spain

    Background/Purpose: Patients with immune-mediated inflammatory diseases (IMIDs) receiving Janus Kinase Inhibitors (JAKi) are at increased risk of herpes zoster reactivation. The adjuvanted recombinant zoster vaccine…
  • Abstract Number: 2040 • ACR Convergence 2025

    Steroid Psychosis and Neuropsychiatric Symptoms induced by Corticosteroid Injection in Rheumatology Patients

    Morvarid Kavosh1, Virva Walkington1, Jigisha Rakholiya1, Krystle Tapia2, Maheswari Muruganandam1, N. Suzanne Emil1, Frank O'Sullivan3 and Wilmer Sibbitt1, 1University of New Mexico, Albuquerque, NM, 2University of New Mexico Hospital, Albuquerque, NM, 3University of New Mexico, Albuquerque

    Background/Purpose: Musculoskeletal (MS) corticosteroid (CS) injections are commonly used for joint inflammation with a perceived low risk of systemic toxicity, including hyperglycemia and adrenal suppression.…
  • Abstract Number: 1729 • ACR Convergence 2025

    The ERIN Registry: Real-World Data on Rheumatic Immune-Related Adverse Events from Immune Checkpoint Inhibitor Therapy

    Didzis Gailis1, Fabian T.H. Ullrich1, Sophia Dombret1, Rebecca Hasseli-Fräbel2, Marc Schmalzing3, Torsten Witte4, Mara Oleszowsky5, Marcel Müller6, Karolina Gente7, Uta Kiltz8, Christof Specker9, Alla Skapenko10 and Hendrik Schulze-Koops10, 1Division of Rheumatology and Clinical Immunology, Department of Internal Medicine IV, LMU University Hospital, Münich, Bayern, Germany, 2Section of Rheumatology and Clinical Immunology, University Hospital Munster, Münster, Nordrhein-Westfalen, Germany, 3Department of Medicine II, Rheumatology/ Immunology,University Hospital of Wuerzburg, Wuerzburg, Bayern, Germany, 4Dept of Rheumatology and Immunology, Hannover, Niedersachsen, Germany, 5Private Rheumatology Practice, Köln, Nordrhein-Westfalen, Germany, 6The Institute for Medical Information Processing, Biometry, and Epidemiology, LMU University Hospital, München, Bayern, Germany, 7Department of Internal Medicine V - Hematology, Oncology and Rheumatology, University Hospital Heidelberg, Heidelberg, Baden-Wurttemberg, Germany, 8Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 9Department of Rheumatology and Clinical Immunology, Kliniken Essen-Mitte, Düsseldorf, Nordrhein-Westfalen, Germany, 10LMU Hospital, Division for Rheumatology and Clinical Immunology, Munich, Bayern, Germany

    Background/Purpose: Immune checkpoint inhibitors (ICIs) are a mainstay of cancer immunotherapy. However, their increasing use has led to more immune-related adverse events (irAEs), including rheumatic…
  • Abstract Number: 1730 • ACR Convergence 2025

    Oral glucocorticoid treatment for checkpoint inhibitor associated inflammatory arthritis do not affect progression free survival: a RADIOS Registry cohort study

    Deanna Jannat-Khah1, Pankti Reid2, Maria Suarez-Almazor3, Noha Abdel-Wahab4, Jeffrey Sparks5, Tawnie Braaten6, Cassandra Calabrese7, Alexa Meara8, Minerva Nong9, Kyle Ge10, Laura Cappelli11, Ami Shah12, Clifton Bingham13 and Anne R. Bass1, 1Hospital For Special Surgery, New York, NY, 2University of Chicago Medical Center, Chicago, IL, 3MD Anderson Cancer Center, Houston, TX, 4University of Texas MD Anderson Cancer Center, houston, TX, 5Brigham and Women's Hospital, Boston, MA, 6UNIVERSITY OF UTAH, Salt Lake City, UT, 7Cleveland Clinic Foundation, Cleveland Heights, OH, 8The Ohio State University Wexner Medical Center, COLUMBUS, OH, 9Columbia University, New York, 10Hospital for Special Surgery, New York, 11Johns Hopkins School of Medicine, Baltimore, MD, 12Johns Hopkins Rheumatology, Baltimore, MD, 13Johns Hopkins University, Baltimore, MD

    Background/Purpose: As immune checkpoint inhibitor (ICI) usage increases for various cancers the prevalence of rheumatologic immune related adverse events (irAEs) also grows. Glucocorticoids are first…
  • Abstract Number: 1687 • ACR Convergence 2025

    Body Esteem and Sexual Function in Women with Systemic Lupus Erythematosus

    Hector Alejandro Martinez-Espinosa1, Jorge Antonio Esquivel Valerio2, Arantza Michelle Núñez-Elizondo3, Regina Esdeyne Rivera-Villafuerte2, Maria Eugenia Corral-Trujillo3, Gisela Garcia-Arellano2, Rosa Arvizu-Rivera4, Griselda Serna-Peña2, Dionicio A. Galarza-Delgado5 and Jesus Alberto Cardenas-de la Garza6, 1Rheumatology Service, University Hospital “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, México, Monterrey, Nuevo Leon, Mexico, 2Universidad Autónoma de Nuevo León, Rheumatology Service, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo León, México., MONTERREY, Mexico, 3Universidad Autónoma de Nuevo León, Rheumatology Service, Hospital Universitario "Dr. José Eleuterio González", Monterrey, Nuevo León, México., Monterrey, Nuevo Leon, Mexico, 4Hospital Universitario "Dr. José Eleuterio Gonzalez", Escobedo, Nuevo León, Mexico, 5Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico, 6Rheumatology Service, University Hospital “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, México, Monterrey, Mexico

    Background/Purpose: SLE predominantly affects women and is often accompanied by physical changes and psychological distress. Although both body image dissatisfaction and sexual dysfunction are reported…
  • Abstract Number: 1496 • ACR Convergence 2025

    Demyelinating Syndromes in Systemic Lupus Erythematosus: A 23-Year Retrospective Analysis of Clinical Features and Treatment Outcomes from a Tertiary Care Center

    Manikandan Gopal1, Ashish Jacob Mathew2 and john mathew3, 1christian medical college, Vellore, India, 2Christian Medical College, Vellore, Tamil Nadu, India, 3Christian Medical college , Vellore , India, Vellore, Tamil Nadu, India

    Background/Purpose: Systemic Lupus Erythematosus (SLE) with acute myelitis or optic neuritis is rare and causes significant morbidity. Data on these conditions remain limited. This study…
  • Abstract Number: 1351 • ACR Convergence 2025

    Are Glucocorticoids Associated with Worse Overall Survival among Rheumatoid Arthritis Patients Treated with Immune Checkpoint Inhibitors? The Confounding Effect of Dexamethasone

    Deanna Jannat-Khah1, Jeffrey Curtis2, Fenglong Xie3, Ashish Saxena4 and Anne R. Bass1, 1Hospital For Special Surgery, New York, NY, 2Foundation for Advancing Science, Technology, Education and Research, Birmingham, AL, 3The University of Alabama at Birmingham, Birmingham, AL, 4Weill Cornell Medicine, New York

    Background/Purpose: Previous studies suggest that glucocorticoids are associated with worse survival in patients receiving immune checkpoint inhibitors (ICI). This is an important issue for Rheumatoid…
  • Abstract Number: 1313 • ACR Convergence 2025

    Retrospective Analysis of Factors Associated With Fracture in 2855 Patients With Rheumatoid Arthritis, Stratified by Steroid Use

    Jonathan Barnes1, Hamzah Amin2 and marwan Bukhari3, 1Morecambe Bay NHS Trust, Lancaster, United Kingdom, 2Lancaster University, Lancaster, United Kingdom, 3University Hospitals of Morecambe bay NHS foundation trust, Lancaster, United Kingdom

    Background/Purpose: Steroids are used in a proportion of patients with rheumatoid arthritis (RA). Steroids are known to cause a decrease in bone mineral density (BMD),…
  • Abstract Number: 1305 • ACR Convergence 2025

    Clinical outcomes of low-to-moderate–dose glucocorticoids in multisystem inflammatory syndrome in children (MIS-C) – a multicenter study

    Nina Shirman1, Liora Harel2, Gil Amarilyo3, Kfir Kaidar4, Yonatan Butbul Aviel5, Merav Heshin Bekenstein6, Mohamad Hamad Saied7, Ofra Goldzweig8, Adi Miler9 and Yoel Levinsky10, 1Schneider children's medical center of Israe, Tel Aviv, Israel, 2Schneider Children's Medical center, Nettnja, Israel, 3Schneider Children's Medical Center of Israel, Kibbutz Maggal, Israel, 4Pediatric rheumatology, Schneider children's medical center of Israel, Petah Tikva, Israel, 5Pediatric rheumatology, Technion Faculty of Medicine, Haifa, Israel, 6Tel Aviv Medical Center Israel, Binyamina, Tel Aviv, Israel, 7Carmel Medical Centre, Technion Faculty of Medicine, Haifa, Israel, 8Pediatric rheumatology unit, Kaplan medical canter, Rehovot, Israel, 9Pediatric rheumatology unit, Technion Faculty of Medicine, Haifa, Israel, 10Schneider Children's Medical Cenetr of Israel, Tel Aviv University, JERUSALEM, Israel

    Background/Purpose: Multisystem Inflammatory Syndrome in Children (MIS-C) is an autoinflammatory disease following SARS-CoV-2 exposure. The optimal treatment strategy remains under investigation, though intravenous immunoglobulin (IVIG)…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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