ACR Meeting Abstracts

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Abstracts tagged "Connective tissue diseases"

  • Abstract Number: 123 • 2018 ACR/ARHP Annual Meeting

    Non-Hematopoietic Derived TNF Drives Pulmonary Vasculopathy: A New Model of CTD-Associated Pulmonary Hypertension

    Richard Bell1, Maria de la Luz Garcia-Hernandez2, Javier Rangel-Moreno3, Christopher T. Ritchlin2, Homaira Rahimi4 and Edward Schwarz5, 1Center for Musculoskeletal Research, University of Rochester, Rochester, NY, 2Division of Allergy/Immunology and Rheumatology and Center for Musculoskeletal Research, School of Medicine and Dentistry, University of Rochester Medical School, Rochester, New York, USA, Rochester, NY, 3Division of Allergy, Immunology and Rheumatology and Center for Musculoskeletal Research School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA, Rochester, NY, 4Rheumatology, University of Rochester/Golisano Children's Hosp, Rochester, NY, 5Orthopedeatrics, University of Rochester, Rochester, NY

    Background/Purpose: Cardiopulmonary disease is a severe comorbidity in many connective tissue diseases (CTD). Rheumatoid arthritis, systemic sclerosis, and systemic lupus patients are all at increased…
  • Abstract Number: 1306 • 2018 ACR/ARHP Annual Meeting

    Clinical Characteristics and Treatment Patterns in Patients with Interstitial Pneumonia with Autoimmune Features (IPAF)

    Giorgos Loizidis1, Nikhil Jiwrajka2, Colin Ligon3, Mary Porteous2 and Michael D. George4, 1Rheumatology, University of Pennsylvania, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA, 3Internal Medicine, Rheumatology, University of Pennsylvania, Philadelphia, PA, 4Division of Rheumatology, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Interstitial pneumonia with autoimmune features (IPAF) has recently been defined to describe patients with interstitial lung disease (ILD) with certain clinical, serologic, and/or morphologic…
  • Abstract Number: 258 • 2017 ACR/ARHP Annual Meeting

    Prevalence of Echocardiographic Findings in Connective Tissue Diseases – a Retrospective Cohort Study

    Valentin S. Schäfer1, Katharina Weiss2, Andreas Krause2 and Wolfgang A. Schmidt3, 1Immanuel Krankenhaus Berlin, Medical Center for Rheumatology Berlin-Buch, Berlin, Germany, 2Medical Centre for Rheumatology Berlin-Buch, Immanuel Krankenhaus Berlin, Berlin, Germany, 3Medical Center for Rheumatology and Clinical Immunology Berlin-Buch, Immanuel Krankenhaus Berlin, Berlin, Germany

    Background/Purpose: Echocardiography is frequently performed in patients with connective tissue diseases (CTD), mostly to evaluate cardiac involvement or development of pulmonary arterial hypertension (paH). Despite…
  • Abstract Number: 275 • 2017 ACR/ARHP Annual Meeting

    Predictive Factors of Cytomegalovirus Infection in Patients with Connective Tissue Diseases Treated with Immunosuppressive Drugs

    Yusuke Yoshida1, Hiroki Kohno2, Katsuhiro Oi3, Tadahiro Tokunaga3, Tatsuomi Kuranobu3, Takaki Nojima4, Shintaro Hirata3 and Eiji Sugiyama1, 1Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan, 2Hiroshima Prefectural Hospital, Hiroshima, Japan, 3Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan, 4Clinical Immunology and Rheumatolog, Graduate School of Medicine, Kyoto University, Kyoto, Japan

    Background/Purpose: Cytomegalovirus (CMV) infections occur frequently in immunocompromised patients. This disease will be fatal if proper treatment is not done. Therefore, in the treatment of…
  • Abstract Number: 1292 • 2017 ACR/ARHP Annual Meeting

    Long-Term Follow-up of 320 Chilren Born to Mothers with Systemic Autoimmune Diseases: A Multicentre Survey from 24 Rheumatology Centers in Italy

    Maria Grazia Lazzaroni1, Cecilia Nalli1, Laura Andreoli1, Chiara Carini1, Marilia Rodrigues2, Francesca Dall'Ara1, Elena Bartoloni-Bocci3, Roberto Gerli3, Maria Gerosa4, Cecilia B. Chighizola5, Pier Luigi Meroni4, Luigi Sinigaglia6, Paola Conigliaro7, Roberto Perricone7, Ada Corrado8, Francesco Paolo Cantatore8, Salvatore D'Angelo9, Ignazio Olivieri9, Maria Favaro10, Maddalena Larosa10, Andrea Doria10, Amelia Ruffatti11, Elena Generali12, Carlo Selmi13, Marianna Meroni14, Maurizio Cutolo15, Melissa Padovan16, Marcello Govoni16, Giulia Pazzola17, Carlo Salvarani18, Susanna Peccatori19, Giuseppe Paolazzi19, Imma Prevete20, Giovanni Minisola20, Gian Domenico Sebastiani21, Antonio Brucato22, Véronique Ramoni23, Roberto Caporali24, Carlomaurizio Montecucco24, Viola Signorini25, Chiara Tani26, Marta Mosca25, Marica Trevisani27, Nazzarena Malavolta27, Marta Vadacca28, Antonella Afeltra29, Ester Vivaldelli30, Armin Maier30, Elisa Visalli31, Rosario Foti31, Carolina Benigno32, Lucia Zuliani33, Armando Gabrielli33, Corrado Campochiaro34, Elena Baldissera35, Maria Grazia Sabbadini36, Nicoletta Romeo37 and Angela Tincani1, 1University and Spedali Civili of Brescia, Brescia, Italy, 2Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, 3University and Azienda Ospedaliera of Perugia, Perugia, Italy, 4Istituto Ortopedico Gaetano Pini, University of Milan, Milano, Italy, 5Rheumatology, Istituto Auxologico Italiano, University of Milan, Cusano Milanino, Italy, 6Istituto Ortopedico Gaetano Pini, University of Milan, Italy, Milan, Italy, 7Policlinico Tor Vergata of Rome, Rome, Italy, 8Ospedali Riuniti of Foggia, Foggia, Italy, 9San Carlo Hospital of Potenza, Potenza, Italy, 10University and Azienda Ospedaliera of Padova, Padova, Italy, 11Unità di Reumatologia, Dipartimento di Medicina-DIMED, Università di Padova., Padova, Italy, 12Rheumatology and Clinical Immunology, Humanitas Research Hospital, Rozzano (MI), Italy, 13Humanitas Research Hospital of Milan, Rozzano, Italy, 14Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, IRCCS A.O.U. San Martino-IST, University of Genova, Genoa, Italy, Genova, Italy, 15Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, IRCCS San Martino, Genoa, Italy, Genoa, Italy, 16UOC of Rheumatology, University Hospital S. Anna, Cona Ferrara, Italy, 17Azienda Ospedaliera ASMN, Istituto di Ricovero e Cura a Carattere Scientifico of Reggio-Emilia, Reggio-Emilia, Italy, 18Rheumatology Unit, Arcispedale Santa Maria Nuova - IRCCS; Università di Modena e Reggio Emilia, Reggio-Emilia, Italy, 19Azienda Provinciale Servizi Sanitari of Trento, Trento, Italy, 20Azienda Ospedaliera San Camillo of Rome, Roma, Italy, 21Rheumatology, San Camillo Forlanini Hospital, Roma, Italy, 22Struttura Complessa Medicina Interna, ASST Papa Giovanni XXIII, Bergamo, Italy, 23Ospedale Papa Giovanni XXIII of Bergamo, Policlinico San Matteo of Pavia, Bergamo, Pavia, Italy, 24University and Policlinico San Matteo of Pavia, Pavia, Italy, 25University of Pisa, Pisa, Italy, 26Rheumatology Unit, University of Pisa, Pisa, Italy, 27Policlinico S.Orsola-Malpighi, Azienda Ospedaliero-Universitaria of Bologna, Bologna, Italy, 28University Campus Biomedico of Rome, Roma, Italy, 29University Campus Biomedico of Rome, roma, Italy, 30Ospedale of Bolzano, Bolzano, Italy, 31Policlinico Vittorio Emanuele-Ferrarotto-Bambin Gesù of Catania, Catania, Italy, 32University Federico II of Napoli, Napoli, Italy, 33Ospedali Riuniti of Ancona, Ancona, Italy, 34Centre for Rheumatology and Connective Tissue Diseases, UCL Division of Medicine, London, United Kingdom, 35Ospedale San Raffaele of Milan, Milan, Italy, 36Unit of Medicine and Clinical Immunology, Ospedale San Raffaele of Milano, Milan, Italy, 37Ospedale S.Croce e Carle of Cuneo, Cuneo, Italy

    Background/Purpose: Rheumatic Diseases (RD) frequently affect women during reproductive age, therefore counseling on family planning is crucial for their quality of life. Children's outcome is…
  • Abstract Number: 1687 • 2017 ACR/ARHP Annual Meeting

    Efficacy of Rituximab for Connective Tissue Disease-Associated Interstitial Lung Disease: A Single Center Study of 28 Patients

    Sunny Patel1, Samina Hayat2, Gloria Caldito3 and Kristen Erickstad1, 1Rheumatology, Louisiana State University Health Sciences Center Shreveport, Shreveport, LA, 2Rheumatology/Internal Medicine, Louisiana State University Health Sciences Center Shreveport, Shreveport, LA, 3Neurology, Louisiana State University Health Sciences Center Shreveport, Shreveport, LA

    Background/Purpose: Interstitial lung disease (ILD) is a severe pulmonary complication associated with connective tissue diseases (CTDs), resulting in substantial morbidity and mortality. Despite advances in…
  • Abstract Number: 2035 • 2017 ACR/ARHP Annual Meeting

    Clinical Audit of Hydroxychloroquine Dosing and Toxicity Screening in Patients with Inflammatory Arthritis and Connective Tissue Diseases

    Sahil Koppikar1 and Henry Averns2, 1Department of Rheumatology, University of Toronto, Toronto, ON, Canada, 2Private Practice, Kingston, ON, Canada

    Background/Purpose: Hydroxychloroquine (HCQ) is used widely for the treatment of inflammatory arthritides and systemic lupus erythematosus. Recent publications have shown that HCQ toxicity is not…
  • Abstract Number: 2105 • 2017 ACR/ARHP Annual Meeting

    Epidemiology of Interstitial Pneumonia with Autoimmune Features

    Robert Mango1, Ashima Makol2, Cynthia S. Crowson3, Jay H. Ryu4 and Eric L. Matteson2, 1Internal Medicine, Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN, MN, 2Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN, 3Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, MN, 4Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN

    Background/Purpose: Interstitial pneumonia with autoimmune features (IPAF) is a subset of interstitial lung disease (ILD) with clinical features suggestive of, but not sufficient for, a…
  • Abstract Number: 2114 • 2017 ACR/ARHP Annual Meeting

    Interstitial Pneumonia with Autoimmune Features (IPAF): Are There Definable Subsets?

    Sepehr Mesdaghinia1, Julio Arturo Huapaya2, Brainerd Ewarien2 and Virginia D. Steen1, 1Rheumatology, MedStar Georgetown University Hospital, Washington, DC, 2Medicine, MedStar Georgetown University Hospital, Washington, DC

    -       Background/Purpose: Interstitial lung disease (ILD) can be an early manifestation of an occult connective tissue disease (CTD).  It is important to separate these patients…
  • Abstract Number: 2169 • 2017 ACR/ARHP Annual Meeting

    A Two-Center Experience with Rituximab in Patients with Primary Idiopathic Myositis and Overlap Myositis: A Retrospective Observational Study

    Kimberly A. Rehberg1, Morgan M. Brown2, Anna K. Shmagel1, Elie Gertner3 and Jerry A. Molitor1, 1Rheumatic & Autoimmune Diseases, University of Minnesota, Minneapolis, MN, 2HealthPartners Institute, St. Paul, MN, 3Section of Rheumatology, Regions Hospital, St. Paul, MN

    Background/Purpose: Recent studies have suggested the possible benefit of the anti-CD20 agent Rituximab (RTX) in autoimmune myositis (AIM). As AIM is a rare and heterogeneous…
  • Abstract Number: 2677 • 2017 ACR/ARHP Annual Meeting

    Impact of Rheumatologic Evaluation and Serologic Testing on Patients with Fibrotic Interstitial Lung Disease: A Single Center Retrospective Experience

    Lindsey A. MacFarlane1 and Paul F. Dellaripa2, 1Rheumatology, Brigham & Women's Hospital, Boston, MA, 2Rheumatology, Brigham and Women’s Hospital, Boston, MD

    Background/Purpose: The evaluation of patients who develop interstitial lung disease (ILD) includes an assessment for underlying rheumatic disease or connective tissue disease (CTD). Delineating a…
  • Abstract Number: 1863 • 2016 ACR/ARHP Annual Meeting

    Non-Invasive Investigation of Perfusion, Microvascular Structure, Erythema, Oxidative Stress and Oxygenation in Healthy Controls and in Patients with Primary and Secondary Raynaud’s Phenomenon

    Andrea Murray1,2, Tonia Moore3, Joanne Manning4, Ian Poxon2, Graham Dinsdale1, Michael Berks5, Sarah Leggett6, Mark Dickinson2 and Ariane L. Herrick1, 1Centre for Musculoskeletal Research, University of Manchester, MAHSC, Salford Royal Hospital, Manchester, United Kingdom, 2Photon Science institute, University of Manchester, Manchester, United Kingdom, 3Centre for Musculoskeletal Research, University of Manchester, MAHSC, Salford Royal Hospital, Salford, United Kingdom, 4Rheumatology Department, Salford Royal NHS Foundation Trust, Salford, United Kingdom, 5Centre for Imaging Sciences, University of Manchester, Institute of Population Health, Manchester, United Kingdom, 6Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom

    Background/Purpose: It is well established that measurements of cutaneous microvascular dysfunction (measured with laser Doppler imaging [LDI]) and structural abnormality (measured with nailfold capillaroscopy [NC])…
  • Abstract Number: 1867 • 2016 ACR/ARHP Annual Meeting

    An Abnormal Nailfold Capillaroscopy Pattern Is Common in Patients with Connective Tissue Disease and Is Associated with Pulmonary and Oesophageal Involvement, Even in the Absence of Systemic Sclerosis

    Anniek M van Roon1, Cato C Huisman1, Arie M van Roon1, Alja J Stel2, Andries J Smit1, Hendrika Bootsma2 and Douwe J Mulder1, 1Internal Medicine - division Vascular Diseases, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 2Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands

    Background/Purpose: RP is a common symptom of CTD. Nailfold capillary microscopy (NCM) has previously been shown to be associated with disease severity and internal organ…
  • Abstract Number: 2806 • 2016 ACR/ARHP Annual Meeting

    A Type-I Interferon Signature Is Associated with Autoantibody Profiles in Connective Tissue Diseases: Results from the Lupus Extended Autoimmune Phenotype (LEAP) Study

    John A. Reynolds1,2, Mumtaz Khan3, Tracy A. Briggs4, Gillian Rice5, Yanick Crow5, Ben Parker6 and Ian N. Bruce1,7, 1NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom, 2Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom, 3Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom, 4Institute of Human Development, University of Manchester, Manchester, United Kingdom, 5Manchester Academic Health Science Centre, Institute of Human Development, University of Manchester, Manchester, United Kingdom, 6Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester Academic Health Sciences Centre, Manchester, United Kingdom, 7Central Manchester University Hospital NHS Foundation Trust and Manchester Academic Health Science Centre, Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester Academic Health Sciences Centre, Manchester, United Kingdom

    Background/Purpose: Type I interferon has been implicated in the pathogenesis of systemic lupus erythematosus (SLE), but much less is known about its role in other…
  • Abstract Number: 2907 • 2016 ACR/ARHP Annual Meeting

    Serum KL-6 Levels in Interstitial Lung Diseases (ILDs) Associated to Connective Tissue Diseases (CTDs)

    Lise Moreer1, Hilario Nunes1, Louise Bondeelle1, Yurdagul Uzunhan1, Pascale Ghillani-Dalbin2, Dominique Valeyre1, Lucile Musset3 and Makoto Miyara3, 1Pulmonary diseases department, Avicenne Hospital (AP-HP), Bobigny, France, 2Department of Immunology, Pitié-Salpêtrière Hospital (AP-HP), Paris, France, 3Department of immunology, Pitié-Salpêtrière Hospital (AP-HP), Paris, France

    Background/Purpose:  ILD is a frequent and potentially severe complication of CTDs. The course of ILD can be difficult to predict in this setting. The term…
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