Abstracts tagged "Computed tomography (CT)"

Abstract Number: 2034 • ACR Convergence 2020
Resolving Phenotypic and Prognostic Differences in Interstitial Lung Disease Related to Systemic Sclerosis by Computed Tomography-based Radiomics
Janine Schniering¹, Malgorzata Maciukiewicz¹, Hubert Gabrys², Matthias Brunner¹, Christian Blütghen³, Chantal Meier¹, Sophie Braga-Lagache⁴, Anne-Christine Ulgry⁴, Manfred Heller⁴, Oliver Distler¹, Matthias Guckenberger², Havard Fretheim⁵, Anna-Maria Hoffmann-Vold⁵, Christos Nakas⁶, Thomas Frauenfelder³, Stephanie Tanadini-Lang² and Britta Maurer⁷, ¹Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Switzerland, Zurich, Switzerland, ²Department of Radiation Oncology, University Hospital Zurich, Switzerland, Zurich, Switzerland, ³Institute of Diagnostic and Interventional Radiology, University Hospital Zurich, Switzerland, Zurich, Switzerland, ⁴Proteomics and Mass Spectrometry Core Facility, Department for BioMedical Research (DBMR), University of Bern, Switzerland, Bern, Switzerland, ⁵Department of Rheumatology, Oslo University Hospital, and Institute of Clinical Medicine, University of Oslo, Norway, Oslo, Norway, ⁶Laboratory of Biometry, University of Thessaly, Volos, Greece, Volos, Greece, ⁷Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, Switzerland, Zurich
Background/Purpose: Radiomics describes the in-depth analysis of tissue phenotypes by computational retrieval of high-dimensional quantitative imaging features including tissue intensity, texture, and wavelet characteristics. Here,…
Abstract Number: 0485 • ACR Convergence 2020
Non-obese Rheumatoid Arthritis Patients with Low Low-density Lipoprotein Have Higher Coronary Atherosclerosis Burden, Greater Plaque Progression and Cardiovascular Event Risk
George Karpouzas¹, Sarah Ormseth¹, Elizabeth Hernandez¹ and Matthew Budoff¹, ¹Harbor-UCLA Medical Center and the Lundquist Institute, Torrance, CA
Background/Purpose: RA patients with low body weight incur higher mortality than obese patients. Paradoxically, RA patients in the lowest low-density lipoprotein group (LDL < 70…
Abstract Number: 0486 • ACR Convergence 2020
Differences in Low-density Lipoprotein (LDL) Particle Composition and Oxidation May Underlie the Paradoxical Association of Low LDL with Higher Coronary Atherosclerosis Burden in Rheumatoid Arthritis
George Karpouzas¹, Sarah Ormseth¹, Elizabeth Hernandez¹ and Matthew Budoff¹, ¹Harbor-UCLA Medical Center and the Lundquist Institute, Torrance, CA
Background/Purpose: Rheumatoid arthritis (RA) patients in the lowest LDL group (< 70mg/dl) experience unexpectedly high cardiovascular risk. We first explored whether this group (Group 1)…
Abstract Number: 0501 • ACR Convergence 2020
Structural Entheseal Lesions in Psoriasis Patients Are Associated with an Increased Risk Ofprogression to Psoriatic Arthritis – A Prospective Cohort Study
David Simon¹, Koray Tascilar¹, Arnd Kleyer¹, Sara Bayat², Eleni Kampylafka², Axel Hueber³, Juergen Rech¹, Louis Schuster¹, Klaus Engel⁴, Michael Sticherling² and Georg Schett⁵, ¹Department of Internal Medicine 3, Friedrich-Alexander University (FAU) Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Bayern, Germany, ²Department of Internal Medicine 3, Friedrich-Alexander University (FAU) Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany, ³Sozialstiftung Bamberg, Sektion Rheumatologie, Bamberg, Germany, ⁴Siemens Healthcare GmbH Digital Technology & Camp; Innovation, SHS DS DTI, Erlangen, Germany, ⁵Friedrich-Alexander-Universität Erlangen- Nuremberg, Erlangen, Germany
Background/Purpose: We have previously reported that the presence of musculoskeletal pain in psoriasis patients is associated with a higher risk of developing psoriatic arthritis (PsA)…
Abstract Number: 0679 • ACR Convergence 2020
Epidemiology of Intra-Articular Mineralization on Knee Dual-Energy Computed Tomography: The Multicenter Osteoarthritis Study
Mohamed Jarraya¹, Tuhina Neogi², John Lynch³, David Felson², Piran Aliabadi⁴, Michael Nevitt³, Cora Lewis⁵, James Torner⁶ and Ali Guermazi², ¹Boston University School of Medicine, Boston, ²Boston University School of Medicine, Boston, MA, ³University of California at San Francisco, San Francisco, ⁴Brigham and Womens Hospital, Boston, ⁵University of Alabama Birmingham, Birmingham, AL, ⁶University of Iowa, Iowa City, IA
Background/Purpose: Computed tomography (CT) has a higher sensitivity for the detection of intraarticular mineralization in comparison with commonly used imaging techniques in knee osteoarthritis (OA)…
Abstract Number: 0691 • ACR Convergence 2020
Denosumab Did Not Improve Computerized Tomography Erosion Scores When Added to Intensive Urate-Lowering Therapy in Gout: Results from a Pilot Study
Angelo Gaffo¹, Kenneth Saag², Anthony Doyle³, Joshua Melnick⁴, Anne Horne⁵, Jeffrey Foster¹, Amy Mudano¹, Stephanie Biggers¹, David Redden¹ and Nicola Dalbeth⁶, ¹University of Alabama at Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, Division of Clinical Immunology and Rheumatology, Birmingham, AL, ³University of Auckland, Grafton, Auckland, New Zealand, ⁴University of Alabama at Birmingham (UAB), Vestavia Hills, AL, ⁵The University of Auckland, Auckland, New Zealand, ⁶University of Auckland, Auckland, New Zealand
Background/Purpose: Bone erosion is a common complication of tophaceous gout. Disordered osteoclast activity has been implicated in the pathogenesis of gouty bone erosion. We sought…
Abstract Number: 0927 • ACR Convergence 2020
Care Gap in Patients with Systemic Sclerosis with CXR Findings Suggestive of Fibrosis
Sandeep Dhillon¹, Jessica Kapralik², Curtis Sobchak³, Nader Khalidi⁴, Martin Kolb⁵, Nathan Hambly², Gerard Cox², Karen Beattie⁴ and Maggie Larche⁴, ¹McMaster University, Burlington, ON, Canada, ²McMaster University, Hamilton, ³McMaster University, St. Catharines, ON, Canada, ⁴McMaster University, Hamilton, ON, Canada, ⁵McMaster University and Firestone Institute for Respiratory Health, St Joseph's Healthcare, Hamliton, ON, Canada
Background/Purpose: Lung involvement, including interstitial lung disease (ILD), is the leading cause of death in patients with systemic sclerosis (SSc). High resolution CT (HRCT) is…
Abstract Number: 0954 • ACR Convergence 2020
Dual-energy CT Predicts Mortality in Gout Patients: A 3-year Follow-up Cohort Study
Anne Marty-Ané¹, Laurène Norberciak², Jean--Francois Budzik³ and Tristan Pascart², ¹GHICL, Lille, France, ²GHICL, Lomme, France, ³University of Lille, Lille, France
Background/Purpose: Cardiovascular events, chronic kidney disease and increased mortality are common in gout patients but what links them remains unclear. Tophaceous gout in particular is…
Abstract Number: 1034 • ACR Convergence 2020
Trend of Treatment Plans, and Outcomes of Therapy in Cardiac Sarcoidosis via Analysis of Standardized Uptake Values Score and Ejection Fraction Using a Cardiac PET-CT
Rabia Gill¹, Martin Lavellee¹, Michael Petrides¹, Sarah Ford¹, Gurukripa Kowlgi², Huzaefah Syed³ and Adam Sima³, ¹Virginia Commonwealth University, Richmond, VA, ²Mayo Clinic, Rochester, MN, ³VCU Health, Richmond, VA
Background/Purpose: Pharmacological management of cardiac sarcoidosis (CS) includes immunosuppressive therapy for active lesions, guideline-directed medical therapy for heart failure, and antiarrhythmics. Our goal was to observe the various…
Abstract Number: 1111 • ACR Convergence 2020
Intra-Articular Mineralization on Knee CT Increases Risk of Knee Pain: The Multicenter Osteoarthritis Study
Tuhina Neogi¹, John Lynch², Mohamed Jarraya³, David Felson¹, Na Wang¹, James Torner⁴, Cora Lewis⁵, Michael Nevitt⁶ and Ali Guermazi¹, ¹Boston University School of Medicine, Boston, MA, ²UCSF, San Francisco, CA, ³Boston University School of Medicine, Boston, ⁴University of Iowa, Iowa City, IA, ⁵University of Alabama Birmingham, Birmingham, AL, ⁶University of California, San Francisco, San Francisco, CA
Background/Purpose: Intra-articular (i.a.) calcium crystal deposition is common in knee osteoarthritis (OA). Low-grade inflammation related to crystals may contribute to knee pain, including pain fluctuation.…
Abstract Number: 301 • 2019 ACR/ARP Annual Meeting
PANLAR Ultrasound Study Group Recommendations for the Use of Imaging in the Management of Patients with Gout
Marwin Gutierrez ¹, Carlos Pineda ¹, Janitzia Vazquez-Mellado ², Mario Moreno Alvarez ³, Javier Rosa ⁴, Anthony Reginato⁵, Mario Chavez ⁶, Magaly Alva Linares ⁷, Marcelo Audisio ⁸, José Alexandre Mendonca ⁹, Tomas Cazenave ¹⁰, Oscar Sedano ¹¹, Lucio Ventura Ríos ¹², Eugenio de Miguel ¹³, Gurjit Kaeley ¹⁴, Eduardo Scheines ¹⁰, Fritz Hofmann ¹⁵, Gabriel Aguilar ¹⁶, Christian Waimann ¹⁷, Florencia Marengo ¹⁷ and Santiago Ruta ¹⁸, ¹Division of Musculoskeletal and Rheumatic Diseases, Instituto Nacional de Rehabilitación “Luis Guillermo Ibarra Ibarra”, Mexico, Mexico, Mexico, ²Rheumatology Department, Hospital General de Mexico, Mexico, Mexico, ³Rheumatology Department, Hospital General Luis Vernaza, Guayaquil, Ecuador., Guayaquil, Ecuador, ⁴Rheumatology Section, Internal Medicine Service, Hospital Italiano de Buenos Aires, Argentina, Buenos Aires, Argentina, ⁵Division of Rheumatology, Providence VAMC, Associate Professor in Medicine, The Warren Alpert School of Medicine, Providence, ⁶Universidad Autónoma de Aguascalientes Aguascalientes, México., Aguascalientes, Mexico, ⁷Rheumatology Department, Hospital Edgardo Rebagliati Martins, Lima, Peru., Lima, Peru, ⁸Rheumatology Department, Hospital Nacional de Clínicas, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Argentina., Cordoba, Argentina, ⁹Rheumatology Department, Pontifical Catholic University of Campinas, Brazil, Campinas, Brazil, ¹⁰Rheumatology Section, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, Buenos Aires, Argentina, ¹¹Reumatology Section, Hospital Marino Molina Scippa, Lima, Perú, Lima, Peru, ¹²Instituto Nacional de Rehabilitación "Luis Guillermo Ibarra Ibarra", México, Mexico, Mexico, ¹³Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, ¹⁴Division of Rheumatology, University of Florida College of Medicine, Jacksonville, FL., Florida, ¹⁵Diagnostik Group, Puerto Vallarta, México., Puerto Vallarta, Mexico, ¹⁶Centro Diagnóstico Rossi, Buenos Aires, Argentina, Buenos Aires, Argentina, ¹⁷Rheumatology Unit, Hospital Dr. Héctor Cura, Olavarría, Argentina., Olavarria, Argentina, ¹⁸Rheumatology Department, Hospital San Martín de La Plata and Rheumatology Unit, Hospital Italiano de La Plata, Argentina., La Plata, Argentina
Background/Purpose: Gout is a metabolic disease caused by deposition of monosodium urate (MSU) monohydrate crystals in different tissues. Imaging may be useful to evaluate the…
Abstract Number: 1168 • 2019 ACR/ARP Annual Meeting
Frequently Encountered Artifacts in Novel Application of Dual-Energy CT to Vascular Imaging: A Pilot Study
Chio Yokose¹, Sterling Eide ², F. Joseph Simeone ¹, Kam Shojania ³, Savvas Nicolaou ⁴, Fabio Becce ⁵ and Hyon K. Choi ¹, ¹Massachusetts General Hospital, Boston, MA, ²National University Hospital of Singapore, Singapore, Singapore, ³Vancouver General Hospital, Vancouver, Canada, ⁴Vancouver General Hospital, Vancouver, BC, Canada, ⁵Lausanne University Hospital, Lausanne, Switzerland
Background/Purpose: One hypothesized link between cardiovascular disease and gout is the direct deposition of monosodium urate (MSU) crystals in atherosclerotic plaque. A 2018 ACR abstract…
Abstract Number: 2616 • 2019 ACR/ARP Annual Meeting
Forced Vital Capacity Trajectories for Systemic Sclerosis-associated Interstitial Lung Disease—Analysis from the University of Michigan Scleroderma Cohort
Mirette Habib¹, Sara Jaafar ¹, Annie Park ¹, Suiyuan Huang ¹, Wen Ye ¹, Vivek Nagaraja ¹, Eric White ¹, Kevin Flaherty ² and Dinesh Khanna ³, ¹University of Michigan, Ann Arbor, MI, ²University of Michigan, Ann Arbor, Michigan, USA, Ann Arbor, MI, ³Department of Medicine, University of Michigan, Ann Arbor, Michigan, USA, Ann Arbor
Background/Purpose: Interstitial Lung Disease (ILD) is the leading cause of morbidity and mortality in systemic sclerosis (SSc) patients. Forced Vital Capacity (FVC, recorded as %…
Abstract Number: 63 • 2018 ACR/ARHP Annual Meeting
TNF-α Blockade Incompletely Reverses Inflammatory Pulmonary Pathology in the TNF-Transgenic Mouse Model of Rheumatoid Arthritis
Emily Wu¹, Richard Bell², Edward Schwarz³ and Homaira Rahimi⁴, ¹Department of Immunology, Microbiology, and Virology, University of Rochester, Rochester, NY, ²Center for Musculoskeletal Research, University of Rochester, Rochester, NY, ³Orthopedeatrics, University of Rochester, Rochester, NY, ⁴Rheumatology, University of Rochester/Golisano Children's Hosp, Rochester, NY
Background/Purpose: Interstitial lung disease (ILD) is a significant contributor to rheumatoid arthritis (RA) mortality, yet its pathogenesis remains enigmatic. One theory posits that initial inflammatory…
Abstract Number: 230 • 2018 ACR/ARHP Annual Meeting
Increased Prevalence of Coronary Artery Disease in Patients with Chest Pain and Seropositive Rheumatoid Arthritis: An Analysis from a Clinical Computed Tomography-Based Large-Scale Population Cohort
Andreas Bugge Tingaard¹, Annette de Thurah², Ina Trolle Andersen³, Anders Hammerich Riis³, Josephine Therkildsen⁴, Ellen-Margrethe Hauge⁵ and Morten Böttcher⁴, ¹Department of Cardiology, Regional Hospital of Herning, Herning, Denmark, ²Department of Rheumatology,, Aarhus University Hospital, Nørrebrogade 44, 8000 Aarhus, Denmark, ³Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark, ⁴Cardiology, Regional Hospital of Herning, Herning, Denmark, ⁵Department of Rheumatology, Aarhus University Hospital, Aarhus, Aarhus, Denmark
Background/Purpose: Inflammation seems to play a central role in the development of atherosclerosis and inflammatory diseases seem to promote progression of coronary artery disease (CAD).…

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