ACR Meeting Abstracts

ACR Meeting Abstracts

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Abstracts tagged "Collagen-Induced Arthritis"

  • Abstract Number: 0738 • ACR Convergence 2020

    Systemic Administration of Novel Hydroxyl Dendrimers to Target Inflammation in Arthritic Tissues

    Jeffrey Cleland1, Rishi Sharma2, Minghao Sun3, Santiago Appiani La Rosa3 and Rangaramanujam M. Kannan4, 1Ashvattha Therapeutics, Inc, Redwood City, CA, 2Ashvattha Therapeutics, Baltimore, MD, 3Ashvattha Therapeutics, Inc, Baltimore, MD, 4Johns Hopkins School of Medicine, Baltimore, MD

    Background/Purpose: Chronic inflammation observed in arthritis and other autoimmune disorders is mediated primarily by pro-inflammatory reactive macrophages.  Systemic administration of anti-inflammatory agents does not selectively…
  • Abstract Number: 0792 • ACR Convergence 2020

    LY294002 Improves the Collagen-induced Arthritis by Inducing Neutrophil Apoptosis

    Xuechan Huang1, Tianwang Li1, Shuyang Chen1, Zhixiang Huang1 and Junming Chen1, 1Department of Rheumatology and Immunology, Guangdong Second Provincial General Hospital, Guangdong, China (People's Republic)

    Background/Purpose: Neutrophils play a central role in host defense, but they also play important effectors on acute and chronic inflammation. Neutrophil apoptosis is essential for…
  • Abstract Number: 0965 • ACR Convergence 2020

    Repetitive Inhalant Lipopolysaccharide Exposure in the Setting of Arthritis Induction Potentiates Pro-Fibrotic Inflammatory Lung Disease in Mice

    Madison Wolfe1, Ted Mikuls1, Geoffrey Thiele1, Amy Nelson1, Michael Duryee1, Rohit Gaurav1, Bryant England1, Debra Romberger1 and Jill Poole1, 1University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Rheumatoid arthritis (RA) is associated with several lung diseases. Various airborne exposures have been implicated as RA disease risk factors including cigarette smoke and…
  • Abstract Number: 1221 • ACR Convergence 2020

    Evaluation of Methotrexate Efficacy and Exploration of Metabolites Associated with Disease Activity in Collagen-induced Arthritis Mouse Model

    Yu Kyoung Cho1 and Ryan Funk1, 1UNIVERSITY OF KANSAS, Kansas City, KS

    Background/Purpose: Methotrexate (MTX) is cornerstone of therapy for rheumatoid arthritis. However, response to MTX is variable and unpredictable among patients. Therefore, there is a critical…
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ACR Convergence: Where Rheumatology Meets. All Virtual. November 5-9.

ACR Pediatric Rheumatology Symposium 2020

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