Abstracts tagged "Cohort Study"

Abstract Number: 0683 • ACR Convergence 2024
Prognostic Value of Systemic Sclerosis-associated Primary Heart Involvement
Caya Gharibian¹, Vanessa Lupi¹, Alexander Gotschy¹, Mike Becker², Rucsandra Dobrota¹, Muriel Elhai³, Sinziana Muraru¹, Suzana Jordan¹, Anna-Maria Hoffmann-Vold⁴, Oliver Distler⁵, Robert Manka¹, Cosimo Bruni¹ and Carina Mihai¹, ¹University Hospital Zurich, University of Zurich, Zurich, Switzerland, ²Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland, ³University Hospital zurich, Zürich, Switzerland, ⁴Oslo University Hospital, Oslo, Norway, ⁵Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Zurich, Switzerland
Background/Purpose: A definition of primary heart involvement (pHI) in systemic sclerosis (SSc) was recently developed (Bruni C et al. J Scleroderma Relat Disord. 2022;7:24-32). Cardiac…
Abstract Number: 1125 • ACR Convergence 2024
Non-Classical Complications of Adult-Onset Still’s Disease: A Multicenter Spanish Study
Javier Narvaez-García¹, Maria Jesus García de Yebenes², Susana Holgado³, Alejandro Olive⁴, Ivette Casafont-Sole³, Santos Castañeda⁵, Cristina Valero⁶, María Martín López⁷, Patricia Carreira⁸, Maribel Mora Limiñana⁹, Laura Nuño¹⁰, Angel Robles Marhuenda¹¹, Pilar Bernabéu¹², J Campos Esteban¹³, Genaro Graña¹⁴, Vera Ortiz¹⁵, Marisol Camacho¹⁶, Carmen Vargas¹⁷, Judith Sanchez-Manubens¹⁸ and Jordi Anton¹⁹, ¹Hospital Universitario de Bellvitge, Barcelona, Spain, ²Instituto de Salud Musculoesquelética, Madrid, Spain, ³Hospital Universitari Germans Trias i Pujol, Badalona, Spain, ⁴Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain, ⁵Hospital Universitario de la Princesa, Madrid, Spain, ⁶Hospital de la Princesa, Madrid, Spain, ⁷General University Hospital of Ciudad Real, Ciudad de México, Spain, ⁸Hospital Universitario 12 de Octubre, Madrid, Madrid, Spain, ⁹Parc Sanitari Sant Joan de Deu, Sant Boi, Barcelona, Spain, ¹⁰Hospital Universitario La Paz, Madrid, Spain, ¹¹Hospital Universitario La Paz, Madrid, Madrid, Spain, ¹²Rheumatology section, Dr. Balmis General University Hospital-ISABIAL, Alicante, Spain, Alicante, Spain, ¹³Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain, ¹⁴Complejo Hospitalario Universitario de A Coruña, La Coruña, Spain, ¹⁵Hospital General de Granollers, Barcelona, Spain, ¹⁶Hospital Universitario Virgen del Rocío, Sevilla, Spain, ¹⁷Hospital Universitario Virgen Macarena, Sevilla, Spain, ¹⁸Hospital Universitari Parc Taulí, Sabadell, Barcelona, Spain, ¹⁹Hospital Sant Joan de Déu, Barcelona, Spain
Background/Purpose: Adult-onset Still's disease (AOSD) is a rare systemic disorder characterized typically by fever, arthritis, skin rash, leukocytosis, and hyperferritinemia, which are the hallmarks of…
Abstract Number: 1390 • ACR Convergence 2024
One-year Real World Evidence Outcomes from the Cohort RADIUS (Real-world Analysis of Upadacitinib in Rheumatoid Arthritis Patients for Improved Understanding and Safety)
Luis Gomez-Lechon Quiros¹, José Miguel Sequí-Sabater², Amalia Rueda³, Costas Torrijo Nerea⁴, Carlos Valera-Ribera⁵, Juan Miguel López-Gómez⁶ and Antonio Alvarez-Cienfuegos⁷, ¹Hospital Francesc de Borja, Valéncia, Spain, ²La Ribera University Hospital, Rheumatology Department, Gandía, Comunidad Valenciana, Spain, ³Hospital General de Valencia, VALENCIA, Comunidad Valenciana, Spain, ⁴Generalitat valenciana, Valencia, Spain, ⁵Hospital Doctor Peset, Valéncia, Comunidad Valenciana, Spain, ⁶Conselleria de Sanitat/Hospital Universitario de Elda, Elda, Comunidad Valenciana, Spain, ⁷Conselleria de Sanitat/Hospital de la Vega Baja, Orihuela, Comunidad Valenciana, Spain
Background/Purpose: Rheumatoid Arthritis (RA) is a chronic inflammatory disease that affects the joints and other parts of the musculoskeletal system. Early diagnosis and initiation of…
Abstract Number: 1714 • ACR Convergence 2024
Avoidable Hospitalizations by Persons with Rheumatoid Arthritis: A Population-Based Study Using Administrative Data
Dani Contreras¹, Claire Barber¹, J. Antonio Avina-Zubieta², Hude Quan¹, Seungwon Lee¹, James King¹ and Cheryl Barnabe¹, ¹University of Calgary, Calgary, AB, Canada, ²Arthritis Research Canada, University of British Columbia, Vancouver, BC, Canada
Background/Purpose: Ambulatory care sensitive conditions (ACSCs) are conditions where appropriate access to ambulatory care can reduce hospitalizations. People with rheumatoid arthritis (RA) are at higher…
Abstract Number: 2231 • ACR Convergence 2024
Treatment Response over the First 6 Months in Newly Diagosed RA Patients by Pain, Anxiety, Depression & Fatigue (PADF) Symptom Clusters: Results from the Canadian Early Arthritis Cohort
Susan Bartlett¹, Orit Schieir², Marie-France Valois¹, Louis Bessette³, Janet Pope⁴, Gilles Boire⁵, Carol Hitchon⁶, Ed Keystone⁷, Carter Thorne⁸, Diane Tin⁸, Glen Hazlewood⁹, Hugues Allard-Chamard¹⁰, Bindee Kuriya¹¹, Vivian Bykerk¹² and Clifton Bingham¹³, and Investigators with the Canadian Early Arthritis Cohort (CATCH), ¹Centre for Outcomes Research & Eval, Montreal, QC, Canada, ²McGill University, Montreal, QC, Canada, ³University of Laval, Quebec City, QC, Canada, ⁴University of Western Ontario, London, ON, Canada, ⁵Retired, Sherbrooke, QC, Canada, ⁶University of Manitoba, Winnipeg, MB, Canada, ⁷Keystone Consulting Enterprises Inc., Toronto, ON, Canada, ⁸Newmarket Rheumatology Consultants, Newmarket, ON, Canada, ⁹University of Calgary, Calgary, AB, Canada, ¹⁰University of Sherbrooke, Sherbrooke, QC, Canada, ¹¹University of Toronto - Toronto, Toronto, ON, Canada, ¹²Hospital for Special Surgery, New York, NY, ¹³Johns Hopkins University, Baltimore, MD
Background/Purpose: Growing evidence suggests that across chronic diseases, patients with co-occurring symptoms of pain, anxiety, and depression (PAD), known as “symptom clusters”, experience variable disease…
Abstract Number: 2419 • ACR Convergence 2024
Clinical and Patient-reported Outcomes in Systemic Lupus Erythematosus: An Analysis of the SLE Prospective Observational Cohort Study (SPOCS) US Data
Richard Furie¹, Mawuena Binka², Gelareh Atefi³, Stephanie Y. Chen⁴ and Bo Ding⁵, ¹Northwell Health, Manhasset, NY, ²BioPharmaceuticals Medical, AstraZeneca, Wilmington, DE, ³AstraZeneca, Media, PA, ⁴BioPharmaceuticals Medical, AstraZeneca, Gaithersburg, MD, ⁵BioPharmaceuticals Medical, AstraZeneca, Gothenburg, Sweden
Background/Purpose: SLE is an autoimmune disease with diverse manifestations and progression patterns that, via disease activity and effects of standard therapy, imposes a significant burden…
Abstract Number: 0423 • ACR Convergence 2024
Higher Risk of Preterm Delivery in Women with Rheumatoid Arthritis: A Matched Comparative Analysis of the GR2 Prospective Cohort and the French National Perinatal Surveys
Sabrina Hamroun¹, Grégoire Martin De Frémont², Nathalie Costedoat-chalumeau³, Marion couderc⁴, René-Marc Flipo⁵, Laure Gossec⁶, Christophe Richez⁷, Rakiba Belkhir⁸, Aline Frazier⁹, Valerie Devauchelle¹⁰, Hubert Marotte¹¹, Jérémie Sellam¹², Elisabeth Gervais¹³, Alban Deroux¹⁴, Cedric Lukas¹⁵, Emmanuelle Dernis¹⁶, Emmanuel Chatelus¹⁷, Véronique Le Guern¹⁸, Gaëlle Guettrot-Imbert¹⁹, Nathalie Lelong²⁰, Camille Le Ray²⁰, Raphaele Seror²¹ and Anna Molto²², and ENP 2021 and GR2 Study Groups, ¹Cochin University Hospital, Paris, Ile-de-France, France, ²Le Kremlin-Bicêtre University Hospital, Le Kremlin-Bicêtre, Guyana, ³University Paris Cité, Paris, France, ⁴CHU de Clermont-Ferrand, Clermont-Ferrand, ⁵CHU Lille, Lille, Nord-Pas-de-Calais, France, ⁶Sorbonne Université, Paris, France, ⁷Pellegrin Hospital, Rheumatology, Referral Center for Rare Systemic Autoimmune and Autoinflammatory Diseases, Bordeaux, France, ⁸Service de Rhumatologie, Hôpital Bicêtre, AP-HP, Le Kremlin-Bicêtre, France, ⁹Lariboisière University Hospital, Paris, France, ¹⁰UBO, Brest, France, ¹¹Université Jean Monnet, CHU Saint-Etienne, Mines Saint-Etienne, INSERM SAINBIOSE 1059, Saint-Etienne, France, ¹²Saint-Antoine Hospital - AP-HP, Paris, Ile-de-France, France, ¹³University hospital, Poitiers, France, ¹⁴Clinique Universitaire de Médecine Interne, Department of Internal Medicine, Grenoble University Hospital, Grenoble, France, ¹⁵Rheumatology department, CHU Montpellier, Montpellier, France, ¹⁶CH LE MANS, LE MANS, Pays de la Loire, France, ¹⁷Rheumatology department strasbourg, Strasbourg, France, ¹⁸APHP, Hôpital Cochin, Paris, ¹⁹Cochin Hospital, Paris, France, ²⁰University of Paris, INSERM Obstetrical, Perinatal and Pediatric Epidemiology Research Team, Paris, France, ²¹Service de Rhumatologie, Hôpital Bicêtre, AP-HP, le Kremlin Bicetre, Ile-de-France, France, ²²Groupe Hospitalier Cochin, AP-HP, Paris, France
Background/Purpose: Rheumatoid arthritis (RA) regularly affects women of childbearing age1. A higher obstetric morbidity in women with RA is suggested in the literature in several…
Abstract Number: 0737 • ACR Convergence 2024
Rurality and Delayed Diagnosis of Giant Cell Arteritis – a Single Center Experience
Ruoning (Lemon) Ni¹, Bharat Kumar² and Aleksander Lenert³, ¹Cleveland Clinic, Cleveland, OH, ²University of Iowa Hospitals and Clinics, Iowa City, IA, ³University of Iowa, Iowa City, IA
Background/Purpose: Giant Cell Arteritis (GCA) poses diagnostic challenges, especially in rural areas, where limited access to healthcare can delay diagnosis and worsen outcomes, a concern…
Abstract Number: 1145 • ACR Convergence 2024
Clinico-Immunological Profile and Treatment Outcomes of Clinically Significant Diaphragmatic Weakness in Patients with Idiopathic Inflammatory Myopathies: Results from the Largest Single-Center Cohort of 16 Cases
Siddharth Jain¹, Bhargavi Pridhivi², Adil Rashid Khan², Stanzin Spalkit², Manish Soneja², Mehar Chand Sharma², Sanjeev Sinha², Uma Kumar² and Naveet Wig², ¹All India Institute of Medical Sciences, New Delhi, Delhi, Delhi, India, ²All India Institute of Medical Sciences, New Delhi, Delhi, India
Background/Purpose: Diaphragmatic myositis is rarely reported in patients with idiopathic inflammatory myopathy (IIM) but is associated with high morbidity and mortality. Epidemiology, spectrum of clinical…
Abstract Number: 1397 • ACR Convergence 2024
Temporal Trends in Early Rheumatoid Arthritis (ERA) Patients with Moderate to Severe Disease Activity: A Multicenter Cohort Study of Treatment Strategies and Outcomes in Chinese Patients in the Modern Era
Yafang Deng¹, Chen Yu², Lin Qiao¹, Nan Jiang¹, Yanhong Wang³, Xinping Tian¹, Qian Wang¹, Mengtao Li⁴ and Xiaofeng Zeng¹, ¹Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, ²Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Dong Cheng Qu, China (People's Republic), ³Department of Epidemiology and Biostatistics, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, ⁴Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China 2National Clinical Research Center for Dermatologic and Immunologic Diseases (NCRC-DID), Ministry of Science & Technology, Beijing, China
Background/Purpose: In the contemporary era, the continuous update of international rheumatoid arthritis (RA) guidelines has significantly impacted the diagnosis and management of RA patients in…
Abstract Number: 1720 • ACR Convergence 2024
Herpes Zoster Risk Following Initiation of Immunosuppressive Therapy Among Adults with Rheumatic Disease
Justin Gatwood¹, Yong Zhu², Andrea Steffens², Stephanie Gallagher², Mary DuCharme² and Nikita Stempniewicz¹, ¹GSK, Philadelphia, PA, ²Optum Life Sciences, Eden Prairie, MN
Background/Purpose: Previous studies have demonstrated that the risk of herpes zoster (HZ) among adults with rheumatic disease, such as rheumatoid arthritis (RA), psoriatic arthritis (PsA),…
Abstract Number: 2232 • ACR Convergence 2024
Anti-RA33 Autoantibodies Are Unique, Sensitive Biomarkers for the Identification of Seronegative Rheumatoid Arthritis in a U.S. Cohort
Andrew Concoff¹, Touba Warsi², Sepehr Taghavi², Sudha Kumar², Abigail Patalinghug², Christine Schleif², Brittany Partain³, Joseph Ahearn⁴, Nicole Wilson⁵, Susan Manzi⁵, Veena Joy⁶ and Tyler O'Malley⁷, ¹Exagen, Inc., Los Angeles, CA, ²Exagen, Carlsbad, CA, ³Exagen, Boston, MA, ⁴Allegheny Health Network, Wexford, PA, ⁵Allegheny Health Network, Pittsburgh, PA, ⁶ThermoFisher, Philadelphia, PA, ⁷Exagen, Vista, CA
Background/Purpose: Novel autoantibodies (Ab) capable of identifying unique subgroups of seronegative rheumatoid arthritis (SN-RA) while providing specificity for RA comparable to ACPA reflects an opportunity…
Abstract Number: 2438 • ACR Convergence 2024
Reduction in Oral Corticosteroid Use During Anifrolumab Therapy: Observations from a Real-world Cohort of Adults with Systemic Lupus Erythematosus
Vasileios Kyttaris¹, Gelareh Atefi², Dan Persons³, Dana Withrow³ and Mawuena Binka⁴, ¹BIDMC, Boston, MA, ²AstraZeneca, Media, PA, ³Trio Health, Louisville, CO, USA, Louisville, ⁴BioPharmaceuticals Medical, AstraZeneca, Wilmington, DE
Background/Purpose: Oral corticosteroids (OCS) are a mainstay in the clinical management of systemic lupus erythematosus (SLE). However, prolonged use may result in systemic side effects.1…
Abstract Number: 0110 • ACR Convergence 2024
Binding Characteristics of Patient Clusters Among Anticardiolipin and Anti-β2-Glycoprotein I ELISA and Non-ELISA Assays: A Survey by the Association of Medical Laboratory Immunologists
Rohan Willis¹, Vijaya Murthy², Karen Roye-Green³, Amy Thees⁴, May Choi⁵, Ken Dier⁶, Marvin Fritzler⁷, Susan Fink⁸, Vijayalakshmi Nandakumar⁹, Melissa Snyder¹⁰ and Anne Tebo¹¹, and the Association of Medical Laboratory Immunologists, ¹University of Texas Medical Branch, Galveston, TX, ²University of Texas Medical Branch (UTMB), League City, TX, ³University of the West Indies, Kingston, Jamaica, ⁴Clinical Immunology Laboratory, Rosalind Franklin University of Medicine and Science, North Chicago, IL, ⁵University of Calgary, Calgary, AB, Canada, ⁶Corgenix, Broomfield, CO, ⁷Mitogen Diagnostics Corp, Calgary, AB, Canada, ⁸Clinical Immunology Laboratory, University of Washington Medical Center, Seattle, WA, ⁹ARUP/University of Utah, Salt Lake City, UT, ¹⁰Clinical Biochemistry and Immunology, Antibody Immunology Laboratory, Mayo Clinic, Rochester, MN, ¹¹Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
Background/Purpose: We have recently shown that anti-phospholipid (APL) assays of varying methodology demonstrate comparable analytical performance despite variable levels of agreement among individual analytes, identifying binding…
Abstract Number: 0438 • ACR Convergence 2024
Overweight and Obesity Are Key Modifiable Risk Factors for Adverse Outcomes in SLE Pregnancies
Jessica Boivin¹, Karim Sacre², Sasha Bernatsky³, Ann E. Clarke⁴, Megan Barber⁴, Paul Fortin⁵, John Hanly⁶, Alexandra Legge⁷, Sang-Cheol Bae⁸ and Evelyne Vinet⁹, ¹McGill University, Montreal, QC, Canada, ²Université de Paris, Paris, France, ³Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ⁴Division of Rheumatology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, ⁵Centre ARThrite - CHU de Québec - Université Laval, Quebec, QC, Canada, ⁶Dalhousie University, Halifax, NS, Canada, Halifax, NS, Canada, ⁷Dalhousie University, Halifax, NS, Canada, ⁸Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, ⁹McGill University Health Centre, Montreal, QC, Canada
Background/Purpose: High maternal body mass index (BMI) is a well-established modifiable risk factor for adverse pregnancy outcomes (APO) in the general obstetric population. Best practices…

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