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Abstracts tagged "Cohort Study"

  • Abstract Number: 1346 • ACR Convergence 2025

    Preliminary Result of Investigating the Response of Conventional Disease-Modifying Antirheumatic Drugs (cDMARDs) Associated SNPs: One Cohort Study

    YU Chen1, Chien-Sheng Wu2, Jacob Shujui Hsu3 and Pei-Lung Chen4, 1Division of Rheumatology, Allergy and Immunology, Far Eastern Memorial Hospital, New Taipei City, Taiwan, R.O.C. Graduate Institute of Medical Genomics and Proteomics, National Taiwan University, Taipei, Taiwan, R.O.C., New Taipei City, Taiwan (Republic of China), 2Division of Rheumatology, Allergy and Immunology, Far Eastern Memorial Hospital, New Taipei City, Taiwan, R.O.C., New Taipei city, Taiwan (Republic of China), 3Graduate Institute of Medical Genomics and Proteomics, National Taiwan University, Taipei, Taiwan, R.O.C., Taipei city, Taiwan (Republic of China), 4Graduate Institute of Medical Genomics and Proteomics, National Taiwan University, Taipei, Taiwan, R.O.C., Taipei, Taiwan (Republic of China)

    Background/Purpose: Multiple Single-Nucleotide Polymorphisms (SNPs), including those in the methotrexate and azathioprine metabolic pathways, are associated with poor response to conventional disease-modifying anti-rheumatic drugs (cDMARDs)…
  • Abstract Number: 1099 • ACR Convergence 2025

    Safety and Effectiveness of Hydroxychloroquine in the Treatment of Rheumatic Immune-Related Adverse Events

    Grace Haeun Lee1, Gregory Challener2, Janeth Yinh3, Jeffrey Sparks4, Kerry L. Reynolds5, Donald P. Lawrence5, Meghan J. Mooradian5, Ryan J. Sullivan5, Hyon K. Choi6 and Minna Kohler7, 1Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, MA, 2Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, 3Massachusetts General Hospital, Boston, MA, 4Brigham and Women's Hospital, Boston, MA, 5Massachusetts General Hospital, Boston, 6MASSACHUSETTS GENERAL HOSPITAL, Lexington, MA, 7Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Hydroxychloroquine (HCQ) has been recommended [1-3] as a steroid-sparing agent for immune checkpoint inhibitor-inflammatory arthritis (ICI-IA), preferred due to its low immunosuppressive effect. However,…
  • Abstract Number: 0553 • ACR Convergence 2025

    Modified A-Tool: An online self-screening tool for axial spondyloarthritis for patients with chronic back pain

    Zeyu Tang1 and Abhijeet Danve2, 1Yale School of Medicine, New Haven, CT, 2Section of Rheumatology, Department of Medicine, Yale School of Medicine, New Haven, CT

    Background/Purpose: Lack of timely rheumatology referral of chronic back pain (CBP) patients with suspected axial spondyloarthritis (axSpA) is a major contributor to delayed diagnosis. We…
  • Abstract Number: 0385 • ACR Convergence 2025

    Musculoskeletal Ultrasound Enhances Patient Insight and Clinical Decisions: A Multi-Center Study

    Simran Nimal1, Meridith Balbach2, Aslam Fawad1, Midori Nishio3 and Erin Chew2, 1Mayo Clinic Arizona, Scottsdale, AZ, 2Vanderbilt University, Nashville, TN, 3John Muir Specialty Medical Group, Lafayette, CA

    Background/Purpose: Musculoskeletal ultrasound (MSKUS) is a valuable tool for early detection and management of inflammatory arthritis.(1) Although integrated into rheumatology guidelines, training programs, and classification…
  • Abstract Number: 0158 • ACR Convergence 2025

    Association between newer COVID-19 vaccines and COVID-19 related hospitalizations among people with autoimmune rheumatic diseases in the U.S. National COVID Cohort Collaborative (N3C)

    Lesley Jackson1, jerrod anzalone2, Rahima Begum3, Fazlur Rahman1, Namrata Singh4, Londyn Robinson5, Kaleb Michaud2, Kenneth Saag6, Jasvinder Singh7, Rena Patel1 and Maria I. ("Maio") Danila8, 1University of Alabama at Birmingham, Birmingham, AL, 2University of Nebraska Medical Center, Omaha, NE, 3University of Alabama at Birmingham, Birmingham, 4University of Washington, Bellevue, WA, 5University of Washington, Seattle, WA, 6The University of Alabama at Birmingham, Birmingham, AL, 7Baylor College of Medicine, Houston, TX, 8University of Alabama at Birmingham (UAB), Birmingham VA Medical Center, Birmingham, AL

    Background/Purpose: People with autoimmune rheumatic diseases (AIRD) are at higher risk for serious complications and poor outcomes from COVID-19 infection. Data is lacking on outcomes…
  • Abstract Number: 2657 • ACR Convergence 2025

    Incidence of Rheumatic Diseases Among Patients Receiving GLP-1 Receptor Agonists: A Comparative Analysis with DPP-4 Inhibitors in a Propensity Score-Matched Cohort

    Betul Ibis1, Furkan Bahar1, Yu-Che Lee2, Ko-Yun Chang3, Yu Chang4 and Cho-Han Chiang5, 1Mount Auburn Hospital, Harvard Medical School, Cambridge, MA, 2University at Buffalo, Buffalo, NY, 3National Jewish Health, Denver, CO, 4National Cheng Kung University Hospital, Tainan, Taiwan (Republic of China), 5Mount Auburn Hospital, Harvard Medical School, Cambridge

    Background/Purpose: GLP-1 receptor agonists (GLP-1RAs) are increasingly utilized in diabetes mellitus management due to their glucose-lowering and cardiovascular benefits. However, the effect of GLP-1RAs on…
  • Abstract Number: 2389 • ACR Convergence 2025

    A Comparison of Patients with Older Onset vs. Younger Onset SLE: A Retrospective Cohort Study

    Chelsea Guan1, Milad Heydari-Kamjani2, Keri Ann Pfeil1, Elleson Harper1, Lindsay Frumker3, Meghan Gump1 and Omer Pamuk2, 1University Hospitals Cleveland Medical Center/Case Western Reserve University, Cleveland, OH, 2University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH, 3University hospitals Cleveland medical center, Highland Heights, OH

    Background/Purpose: SLE is a systemic autoimmune disease that can present at different ages and with various multiorgan complications. In this study, we aimed to analyze…
  • Abstract Number: 2074 • ACR Convergence 2025

    Increased Mortality in Hispanic Males with Lymphopenia: A Descriptive and Statistical Analysis of Anti-Melanoma Differentiation-Associated Protein 5 (MDA-5) Antibody Positive Patients

    Sergio Maldonado Chaar1 and Kelly Corbitt2, 1University of Miami/Jackson Health, Miami, FL, 2University of Miami Miller School of Medicine, El Portal, FL

    Background/Purpose: Anti-melanoma differentiation-associated protein 5 (MDA-5) antibody positivity in dermatomyositis (DM) is often associated with development of interstitial lung disease (ILD), with factors such as…
  • Abstract Number: 1842 • ACR Convergence 2025

    Social Vulnerability Index, Type 2 Lupus Symptoms, and Select Dysregulated Immune Features Identify Stage 2 (Pre-classification) SLE in the Lupus Autoimmunity in Relatives (LAUREL) Follow-up Cohort

    Melissa Munroe1, Zoe Reed2, Joel Guthridge2, Diane Kamen3, Timothy Niewold4, Kendra Young5, Angel Weng5, Emma Wu5, Gary Gilkeson6, Michael Weisman7, Mariko Ishimori7, Daniel Wallace8, John Harley9, David Karp10, Jill Norris11 and Judith James2, 1Oklahoma Medical Research Foundation; Progentec Diagnostics, Inc., Oklahoma City, OK, 2Oklahoma Medical Research Foundation, Oklahoma City, OK, 3Medical University of South Carolina, Johns Island, SC, 4Hospital for Special Surgery, New York, New York, 5Colorado School of Public Health, Aurora, CO, 6Medical University of South Carolina, Charleston, SC, 7Cedars-Sinai Medical Center, LOS ANGELES, CA, 8Cedars Sinai Medical Center, Studio City, CA, 9US Department of Veterans Affairs Medical Center, Cincinnati, OH, 10UT Southwestern Medical Center, Dallas, TX, 11Colorado School of Public Health, Denver, CO

    Background/Purpose: Socioeconomic environmental factors are associated with SLE disease activity and early mortality and may contribute to disease progression in at-risk populations. Blood relatives (BRs)…
  • Abstract Number: 1541 • ACR Convergence 2025

    Tofacitinib versus Belimumab in maintenance therapy of Systemic Lupus Erythematosus: A Real-World Study of the CSTAR cohort

    Qizhi Yuan1, Qinli Qin2, Leyao Ma1 and Mengtao Li3, 1Peking Union Medical College Hospital, Beijing, China (People's Republic), 2Dongguan Kanghua Hospital, Dongguan, Guangdong, China (People's Republic), 3Peking Union Medical College Hospital, Beijing, Beijing, China (People's Republic)

    Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease with multi-organ involvements and recurrent relapses. The objectives of treatment include ensuring long-term patient survival, preventing…
  • Abstract Number: 1339 • ACR Convergence 2025

    Inflammatory Rheumatic Diseases in IDH-mutated Myeloid Neoplasms: Clinical Spectrum and Response to IDH Inhibitors

    Romain Stammler1, Peter Chen2, Orianne Debeaupuis2, Lin Pierre Zhao1, Mirabelle Ruyer Thompson1, Eve Zakine1, Julien Rossignol1, Lauriane Goldwirt1, Thibault Comont3, Mael Heiblig4, Lionel Ades1, Marie Sebert1, Jean-sébastien Allain5, Julien Campagne6, Marie Anne Couturier7, Marina Cumin8, Marie Caroline Dalmas9, Guillaume Denis10, Cecile Devloo11, Adrien De Voeght12, Louis Drevon1, Pierre Duffau13, Sophie georgin-Lavialle14, Delphine Gobert1, Noemie Abisror15, Olivier Kosmider16, Fréderic Rieux-Laucat2, Estibaliz LAZARO17, Jean Guillaume Lopez18, Alexandre Maria19, Wladimir Mauhin20, Julie Merindol21, Claire Merlot22, Tristan Mirault1, Laurent Pascal23, François Perrin24, Emmanuel Raffoux1, Ramy Rahme25, Damien Roos-Weil1, Benjamin Terrier26, Benjamin Torreau27, Olivier Fain1, Pierre Fenaux1, Pierre Hirsch1, Vincent Jachiet1, Jerome Hadjadj1 and Arsène Mekinian28, 1Assistance Publique des Hôpitaux de Paris, Paris, France, 2Imagine Institute, Paris, France, 3Centre Hospitalier Universitaire Toulouse Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, France, 4Lyon-Sud Hospital, Hospices Civils de Lyon, Paris and Université Claude Bernard, Lyon, France, 5Scorff-Lorient Hospital, Lorient, France, 6Hospital Robert Schuman, Metz, France, 7Centre Hospitalier Régional et Universitaire de Brest, Brest, France, 8Centre hospitalier de Libourne, Libourne, France, 9Strasbourg University Hospital Center, Strasbourg, France, 10Centre Hospitalier Rochefort, Rochefort, France, 11Centre hospitalier de Dieppe, Dieppe, France, 12CHU of Liège, Liège, Belgium, 13Groupe Hospitalier Saint-André, Bordeaux, France, 14Sorbonne university, Tenon hospital, DMU3ID, CEREMAIA, ERN RITA, Paris, France, 15Internal Medicine, CHU Saint-Antoine,, Paris, France, 16AP-HP, Hopital Cochin, Institut Cochin, CNRS UMR8104, INSERM U1016 Université Paris Cité Paris France., PARIS, France, 17Bordeaux University Hospital, Pessac, France, 18Dupuytren University Hospital, Limoges, France, 19Saint-Eloi Hospital, Montpellier, France, 20Croix Saint Simon Hospital, Paris, France, 21University Hospital of Nice, Nice, France, 22Centre hospitaliser d’Orléans, Orléans, France, 23Hôpital Saint-Vincent de Paul, Lille, France, 24Centre Hospitalier de Saint-Nazaire, Saint Nazaire, France, 25Assistance Publique des Hôpitaux de Paris, Bobigny, France, 26Cochin Hospital, Paris, France, 27Internal Medicine and Immunology, CHU Tours, Tours, France, 28Department of Internal Medicine, Inflammation-Immunopathology-Biotherapy Department (DMU i3), Saint-Antoine University Hospital, 75012 Paris, France, Paris, France

    Background/Purpose: Clonal hematopoiesis has emerged as a key contributor to systemic inflammation, bridging hematologic and immune-mediated inflammatory disorders (IMIDs). Isocitrate dehydrogenase 1 and 2 (IDH1/2)…
  • Abstract Number: 1093 • ACR Convergence 2025

    Rituximab Associated Risk for Progressive Multifocal Leukoencephalopathy Among Patients with Systemic Lupus Erythematosus: A Retrospective Cohort Study

    Blake Baay1, Lorien Nassi2 and Zachary Most3, 1Scottish Rite for Children, Dallas, TX, 2UT Southwestern, Children's Medical Center, and Scottish Rite for Children, Dallas, TX, 3UT Southwestern, Dallas, TX

    Background/Purpose: Rituximab is one of the many immunosuppressive medications used to treat SLE that can increase a patient’s risk for developing progressive multifocal leukoencephalopathy (PML),…
  • Abstract Number: 0838 • ACR Convergence 2025

    Complete Renal Response and Long-Term, Progression-Free Survival in Adult Patients With Lupus Nephritis: A Retrospective Cohort Study in the United States

    Lisa Lindsay1, Shu Wang2, Huong Trinh1, Yunru Huang1, William Pendergraft1 and Brad Rovin3, 1Genentech, Inc., South San Francisco, CA, 2Genesis Research LLC, Hoboken, NJ, 3The Ohio State University, Columbus, OH

    Background/Purpose: Complete renal response (CRR) and flare prevention, as early markers of long-term kidney survival, are important outcomes in lupus nephritis (LN) clinical trials.Methods: This…
  • Abstract Number: 0343 • ACR Convergence 2025

    Impact of Janus Kinase Inhibitors on Bone Mineral Density and Microarchitecture in Rheumatoid and Psoriatic Arthritis: Insights from a Real-World Cohort

    Edgar Wiebe1, Dörte Huscher2, Zhivana Boyadzhieva3, Andriko Palmowski4, Sandra Hermann1, Burkhard Muche4, Arnd Kleyer5, David Simon6, Gerhard Krönke7, Paula Hoff8 and FRANK BUTTGEREIT9, 1Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany, Berlin, Berlin, Germany, 2Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Berlin, Germany, 3Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Berlin, Germany, 4Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany, 5Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany, Berlin, Germany, 6Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany; Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Germany, Berlin, Germany, 7Department of Rheumatology and Clinical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany; Deutsches Rheuma-Forschungszentrum Berlin, Berlin, Germany, Berlin, Berlin, Germany, 8Endokrinologikum Berlin, Medizinisches Versorgungszentrum (MVZ) am Gendarmenmarkt, Berlin, Berlin, Germany, 9Charité University Medicine Berlin, Berlin, Berlin, Germany

    Background/Purpose: Janus kinase (JAK) inhibitors are an important treatment option for rheumatoid arthritis (RA) and psoriatic arthritis (PsA). By disrupting pro-inflammatory cytokine signaling (e.g., IL-6,…
  • Abstract Number: 0137 • ACR Convergence 2025

    Landscape of Primary Antiphospholipid Syndrome: Clinical Spectrum, Serology, and Predictors of Damage in a Single Center Cohort of 233 Patients

    RITESH KUMAR MISHRA1, SUBIN PHILIP2, JAIDEV MENON2, RIZWANA NAUSHAD2, AISHWARYA GOPAL3, CHRISTINA MARIASELVAM2, Chengappa Kavadichanda2, Molly mary Thabah3 and VIR SINGH NEGI2, 1JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH, Bhubaneswar, India, 2JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH, PUDUCHERRY, Puducherry, India, 3JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH, PUDUCHERRY, India

    Background/Purpose: Primary Antiphospholipid Syndrome (APS) a systemic autoimmune prothrombotic disorder with long-term consequences. While secondary APS is well studied, large real-world cohorts of primary APS…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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