ACR Meeting Abstracts

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Abstracts tagged "Cohort Study"

  • Abstract Number: LB16 • ACR Convergence 2025

    Mepolizumab Reduces End-Organ Manifestations Compared with Standard of Care in Patients with EGPA and HES: A US Real-world Analysis

    David Silverman1, Timothy Barnes2, Nnaemeka Odo2, Jared Silver3, Lisa Le2, Amy Edgecomb4 and Hitesh Patel5, 1Rheumatology Department, Kaiser Permanente Colorado Medical Group, Denver, Colorado, 2Value and Evidence Solutions, Optum Life Sciences, Eden Prairie, Minnesota, 3Clinical Development, Amgen, Thousand Oaks, California, 4Anti-infectives and Respiratory, GSK, Philadelphia, Pennsylvania, 5US Medical Affairs, GSK, Durham, North Carolina

    Background/Purpose: Eosinophilic granulomatosis with polyangiitis (EGPA) and hypereosinophilic syndrome (HES) are rare systemic diseases characterized by persistent eosinophilia and tissue infiltration, resulting in end-organ dysfunction…
  • Abstract Number: 2338 • ACR Convergence 2025

    Real-World Outcomes of Combined Tofacitinib and TNF Inhibitor Therapy in Refractory Inflammatory Arthritis: A Tertiary Care Experience from India

    Aashish Agrawal and Balakrishnan Canchi, Hinduja Hospital, Mumbai, Maharashtra, India

    Background/Purpose: The use of combination biologic and targeted synthetic DMARDs remains controversial due to safety concerns, yet may offer benefit in refractory inflammatory arthritis. This…
  • Abstract Number: 2054 • ACR Convergence 2025

    A Changing Paradigm: Reassessing the Role of Muscle Biopsy in Idiopathic Inflammatory Myopathies in a Single-Center Cohort

    Ami Purohit1, Najia Shakoor2, Dmitriy Cherny1 and Juan Schmukler1, 1Rush University Medical Center, Chicago, IL, 2Rush University, Chicago, IL

    Background/Purpose: Idiopathic inflammatory myopathies (IIMs) encompass a heterogenous group of autoimmune diseases characterized by inflammation of muscle and other target organs. Muscle biopsy was historically…
  • Abstract Number: 1721 • ACR Convergence 2025

    Excess Mortality in SLE Is Concentrated in Lupus Nephritis and aPL-Positive Subsets: A population-based inception cohort study

    Mario Bautista-Vargas1, Erika Navarro-Mendoza1, Jaime Flores-Gouyonnet1, Ali Ardekani1, Maria Cuellar-Gutierrez1, Gabriel Figueroa-Parra2, Mariana Gonzalez-Treviño3, Jose Antonio Meade-Aguilar4, Alain Sanchez-Rodriguez5, Andrew C. Hanson1, Cassondra Hulshizer6, Cynthia Crowson7 and Ali Duarte-Garcia1, 1Mayo Clinic, Rochester, MN, 2Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico, 3Vanderbilt University Medical Center, Nashville, TN, 4Boston University/Boston Medical Center, Boston, MA, 5ABC Medical Center, Ciudad de México, Federal District, Mexico, 6Mayo Clinic, Rochester, 7Mayo Clinic, Stewartvillle, MN

    Background/Purpose: Five-year survival in SLE has plateaued since the 1990s. Most epidemiologic studies pool all SLE phenotypes; It is possible that the excess mortality observed…
  • Abstract Number: 1533 • ACR Convergence 2025

    Belimumab Is Associated with Early Improvement in Disease Activity Measures Among Patients with Systemic Lupus Erythematosus in the US

    Yan Chen1, Maral DerSarkissian1, Shumin Rui1, Justin Clark1, Daniel Moldaver2, Jeffrey J. Ellis3, Karen Worley3 and Aarat M Patel4, 1Analysis Group, Los Angeles, CA, 2GSK, Global Real-World Evidence & Health Outcomes Research, Toronto, ON, Canada, 3GSK, Global Real-World Evidence & Health Outcomes Research, Collegeville, PA, 4GSK, US Medical Affairs, Durham, NC

    Background/Purpose: Belimumab (BEL), a B-cell modulator mAb that selectively inhibits soluble B-lymphocyte stimulator and reduces autoreactive B cells that drive lupus disease activity, is approved…
  • Abstract Number: 1220 • ACR Convergence 2025

    Predictors of Progressive Pulmonary Fibrosis in Idiopathic Inflammatory Myopathies : a Retrospective Study of 502 Cases

    Wei Bian1, Jian Hao1, Na zhang1, Xiaojing Zhang1, Fumin Qi1, Yin Zhao2 and Wei Wei1, 1Tianjin Medical University General Hospital, Tianjin, China (People's Republic), 2Affiliated Hospital of Yunnan University, Yunnan, China (People's Republic)

    Background/Purpose: Interstitial lung disease (ILD) in idiopathic inflammatory myopathies (IIM) causes worse prognosis. Some patients develop progressive pulmonary fibrosis (PPF) despite appropriate treatment. Identifying predictors…
  • Abstract Number: 1038 • ACR Convergence 2025

    Real-World Immunosuppressant Treatment Patterns in Lupus Nephritis: A Retrospective Claims Database Analysis in the United States

    Anisha Patel1, Alexandra Miller1, Lisa Lindsay1, Danny Sheinson1, Zhiyu Xia1, William Pendergraft1 and Maria Dall'Era2, 1Genentech, Inc., South San Francisco, CA, 2Division of Rheumatology, University of California, San Francisco, CA

    Background/Purpose: LN is a severe manifestation of SLE requiring intensive management. We aimed to characterize real-world treatment patterns in newly diagnosed patients with LN within…
  • Abstract Number: 0544 • ACR Convergence 2025

    Prevalence and Baseline Characteristics associated with Difficult-to-Manage Axial Spondyloarthritis in the DESIR Cohort

    Olivier Fakih1, Anna Molto2, Frank Verhoeven1, Clément Prati1 and WENDLING Daniel1, 1CHU de Besançon, Besançon, Franche-Comte, France, 2Assistance Publique Hôpitauxde Paris, Paris, France

    Background/Purpose: Despite a choice of multiple targeted DMARDs, with different modes of action (MoA), a number of patients with axial spondyloarthritis (axSpA) have failed several…
  • Abstract Number: 0306 • ACR Convergence 2025

    Direct Assessment of Intestinal Permeability as a Risk Factor for Multiple Joint Osteoarthritis in Community Cohorts of Humans and Pet Dogs

    Liubov Arbeeva1, Virginia Kraus2, Richard Loeser3, Yvonne Golightly4, Hiroko Enomoto5, Masataka Enomoto5, Duncan Lascelles5 and Amanda Nelson6, 1University of North Carolina, Chapel Hill, Carrboro, NC, 2Duke University, Durham, NC, 3University of North Carolina, Chapel Hill, NC, 4University of Nebraska Medical Center, Omaha, NE, 5North Carolina State University, Raleigh, NC, 6University of North Carolina at Chapel Hill, Chapel Hill, NC

    Background/Purpose: Increased intestinal permeability (IP) is common in chronic inflammatory diseases, and can be measured indirectly (e.g., with blood markers such as lipopolysaccharide, LPS), or…
  • Abstract Number: 2606 • ACR Convergence 2025

    The Impact of Social Media and Artificial Intelligence on Illness Perception and Treatment Adherence in Patients with Rheumatic Diseases

    Egla Samantha Sanchez-Peralta1, Pablo Gamez-Siller1, Angel Kevin Garza-Elizondo1, Fabiola Alejandra Fuentes-Rios1, Gemma Alely Garcia-Ramos1, Derek de Jesus Gauna Leal1, Ariana Silva-de Leon1, Nathalia Valdez-Benavides1, Jesus Alberto Cardenas-de la Garza2, Margarita Isabel Alarcon-Jarquin3, Dionicio A. Galarza-Delgado4 and Diana E. Flores-Alvarado1, 1Rheumatology Service, University Hospital “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, México, Monterrey, Nuevo Leon, Mexico, 2Rheumatology Service, University Hospital “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, México, Monterrey, Mexico, 3Rheumatology Service, University Hospital “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, Nuevo Leon, Mexico, 4Rheumatology Service, Hospital Universitario Dr. José Eleuterio González, Universidad Autónoma de Nuevo León, Monterrey, Mexico

    Background/Purpose: Social media (SM) and Artificial Intelligence (AI) are common sources of health information for patients with chronic diseases. Seeking medical information from unreliable sources…
  • Abstract Number: 2331 • ACR Convergence 2025

    Coping with Rheumatic Stressors in Axial Spondyloarthritis: Association with Patient Characteristics and Disease Phenotypes and Changes Over Time

    Marc van Essen1, Dafne capelusnik2, Désirée Van Der Heijde3, Robert Landewé4, Wim van Lankveld5, Astrid Van Tubergen6, Sofia Ramiro7 and Annelies Boonen8, 1Maastricht University, Zeist, Netherlands, 2Tel Aviv Sourasky Medical Center, Ramat Gan, Israel, 3Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 4Department of Rheumatology, Amsterdam University Medical Center, Amsterdam, Netherlands; and Zuyderland Medical Center, Heerlen, Netherlands, 5HAN University of Applied Sciences, Arnhem, Netherlands, 6Maastricht university, Maastricht, Netherlands, 7Leiden University Medical Center, Bunde, Netherlands, 8Maastricht University Medical Centre+ & Maastricht University, Maastricht, Limburg, Netherlands

    Background/Purpose: To identify patient characteristics and disease phenotypes associated with coping strategies in axial spondyloarthritis (axSpA), and assess whether coping strategies change over time.Methods: Data…
  • Abstract Number: 2045 • ACR Convergence 2025

    Malignancy in Behçet’s Syndrome: A 24-Year Cohort Study In a Non-Endemicand Multiethnic Country

    Pedro Araujo1, Rafael Bassara Macedo2, Fabio Specian2, Carolina Ejnisman3, Barbara Bayeh3, Percival Sampaio-Barros4, Thiago Freitas4, Rafael Cordeiro5 and Henrique Giardini4, 1Universidade de São Paulo, Sao Paulo, São Paulo, Brazil, 2Rheumatology Division, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo (USP), Sao Paulo, Sao Paulo, Brazil, 3Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, Sao Paulo, Brazil, 4Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, São Paulo, Brazil, 5Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, São Paulo, Sao Paulo, Brazil

    Background/Purpose: Behçet’s syndrome (BS) has been associated with an increased risk of malignancy, particularly in studies from endemic regions such as East Asia and the…
  • Abstract Number: 1710 • ACR Convergence 2025

    Defining sonographic enthesitis in psoriatic arthritis: Developing a data- and expert-driven definition for inflammatory enthesitis at the single enthesis level

    Andre Lucas Ribeiro1, Sibel Aydin2, Gurjit Kaeley3, Fahmeen J. Afgani4, Catherine Bakewell5, Marcos Rosemffet6, Minna Kohler7, Amir Haddad8, Maria S. Stoenoiu9, Ari Polachek10, josefina marin11, Arnon Katz12, Sahil Koppikar13 and Lihi Eder14, 1Hospital de Clínicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil, 2Department of Medicine, University of Ottawa, The Ottawa Hospital Research Institute, Ottawa, ON, Canada, 3UF COM-J, Ponte Vedra Beach, FL, 4Women's College Hospital, Toronto, Canada, 5Intermountain Healthcare, Salt Lake City, UT, 6Instituto de Rehabilitación Psicofísica, Capital Federal, Argentina, 7Massachusetts General Hospital, Harvard Medical School, Boston, MA, 8Carmel Medical Centre, Haifa, Israel, 9Cliniques Universitaires Saint-Luc, Brussels, Belgium, 10Rheumatology Institute of Beilinson Hospital, Petah Tikva, Israel, 11Hospital Universitario Rey Juan Carlos, Madrid, Spain, 12GRAPPA, Seattle, 13Women's College Hospital & University of Toronto, Markham, ON, Canada, 14University of Toronto, Toronto, ON, Canada

    Background/Purpose: Enthesitis affects 30–40% of PsA patients but remains difficult to diagnose due to overlap with non-specific entheseal pain. While OMERACT has standardized ultrasound (US)…
  • Abstract Number: 1513 • ACR Convergence 2025

    Race, Renal Failure, and Risk: A five-to-ten year retrospective cohort study of Racial differences in outcomes of patients with dialysis-dependent Lupus nephritis

    Ufuoma Mamoh1, Queeneth Edwards2, Chukwuemelie Okeke3, Justin Riley Lam4, Soziema Salia5 and Christhopher Haas6, 1Medstar Health Georgetown University Internal Medicine Residency Program, Baltimore, MD, 2Georgia Southern University, Statesboro, GA, 3Maimonides Medical Center, Brooklyn, NY, 4Albert Einstein Medical Center, Philadelphia, PA, 5MedStar Health Georgetown University (Baltimore) Internal Medicine Program, Baltimore, MD, 6MedStar Health Georgetown University (Baltimore) Internal Medicine Program, Baltimore

    Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that disproportionately affects racial and ethnic minority populations, particularly Black/African American and Hispanic/Latino individuals. In…
  • Abstract Number: 1180 • ACR Convergence 2025

    Gender-Based Clinical Differences in Behçet’s Syndrome: Findings from a 24-Year Cohort in a Non-Endemic and Multiethnic Country

    Rafael Bassara Macedo1, Pedro Araujo2, Fabio Specian1, Carolina Ejnisman3, Barbara Bayeh3, Percival Degrava Sampaio Barros3, Thiago Freitas4, Rafael Cordeiro5 and Henrique Giardini4, 1Rheumatology Division, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo (USP), Sao Paulo, Sao Paulo, Brazil, 2Universidade de São Paulo, Sao Paulo, São Paulo, Brazil, 3Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, Sao Paulo, Brazil, 4Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, São Paulo, Brazil, 5Rheumatology Division, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, São Paulo, Sao Paulo, Brazil

    Background/Purpose: Behçet’s syndrome (BS) is a multisystemic inflammatory condition that affects both genders, although gender-related differences in disease manifestations may vary across regions. Studies report…
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Embargo Policy

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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