Abstracts tagged "Cognitive dysfunction"

Abstract Number: 1401 • 2014 ACR/ARHP Annual Meeting
Higher-Order Neuropsychological Deficits Are Frequent and Occur Early in RA and SLE: The Impact of Basic Processing Abilities on Psychological Well-Being
Giorgia Dimitraki¹, Georgia Ktistaki¹, Emmanouil Papastefanakis¹, Antonis Fanouriakis², Irini Gergiannaki², George Bertsias³, Nikolaos Kougkas², Argyro Repa³, Evangelos Karademas¹, Prodromos Sidiropoulos³ and Panagiotis Simos¹, ¹Department of Psychology, University of Crete, Rethymnon, Greece, ²Rheumatology, Clinical Immunology and Allergy, University of Crete, Heraklion, Greece, ³Rheumatology, Clinical Immunology, and Allergy, University of Crete, Heraklion, Greece
Background/Purpose Deficits in higher-order cognitive abilities (episodic memory, executive functions) have been reported in patients with chronic inflammatory disorders, albeit inconsistently. We investigated whether such…
Abstract Number: 1107 • 2014 ACR/ARHP Annual Meeting
A Strong Association Between Memory Loss and Word Finding Difficulties in Fibromyalgia
Robert S. Katz¹ and Frank Leavitt², ¹Rush Medical College, Chicago, IL, ²Rush University Medical Center, Chicago, IL
Background/Purpose: A core feature of fibromyalgia (FMS) is cognitive dysfunction. The predominant clinical manifestations is memory loss; however impaired word retrieval frequently referred to…
Abstract Number: 2202 • 2013 ACR/ARHP Annual Meeting
TNF-α Is Associated With Cognitive Impairment In Childhood-Onset Systemic Lupus Erythematosus
Mariana Postal¹, Nailu A. Sinicato¹, Aline T. Lapa¹, Karina Peliçari¹, Bruna Bellini¹, Paula T Fernandes², Roberto Marini³ and Simone Appenzeller⁴, ¹Medicine, State University of Campinas, Campinas, Brazil, ²Faculty of Physical Education, State University of Campinas, Campinas, Brazil, ³State University of Campinas, Campinas, Brazil, ⁴Medicine, Faculty of Medical Science, State University of Campinas Unicamp, São Paulo, Brazil
Background/Purpose: Cognitive impairment is common in over 50% of SLE patients with active neurological and psychiatric disorders. Cytokine dysregulation and inﬂammation are mechanisms that may…
Abstract Number: 1602 • 2013 ACR/ARHP Annual Meeting
Autoantibodies, Cytokines and Chemokines In Serum and Cerebrospinal Fluid Of SLE Patients With Cognitive Dysfunction
Hilda Fragoso-Loyo¹, Alí Duarte-García², Sandra Juárez-Arellano³, Alba Cicero-Casarrubias⁴, Juanita Romero-Díaz⁵, Luis LLorente-Peters¹ and Jorge Sánchez-Guerrero⁶, ¹Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico, Mexico, ²Department of Medicine, Tufts Medical Center, Boston, MA, ³Department of Neurology, Instituto Nacional de Ciencias Medicas y Nutricion S.Z., Mexico city, Mexico, ⁴Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ⁵Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion, Mexico City, Mexico, ⁶Rheumatology, Mount Sinai Hospital and University Health Network, Toronto Canada, Toronto, ON, Canada
Background/Purpose: The nature and pathogenesis and cognitive dysfunction (CD) in patients with SLE is unkown.To determine the presence and levels of autoantibodies, cytokines and chemokines…
Abstract Number: 1260 • 2013 ACR/ARHP Annual Meeting
Serum S100β Is Associated With Neuropsychiatric Manifestations In Childhood-Onset Systemic Lupus Erythematosus
Aline T. Lapa¹, Mariana Postal¹, Nailu A. Sinicato¹, Bruna Bellini¹, Paula T Fernandes², Roberto Marini³ and Simone Appenzeller⁴, ¹Medicine, State University of Campinas, Campinas, Brazil, ²Faculty of Physical Education, State University of Campinas, Campinas, Brazil, ³State University of Campinas, Campinas, Brazil, ⁴Medicine, Faculty of Medical Science, State University of Campinas Unicamp, São Paulo, Brazil
Background/Purpose: Involvement of the central nervous system (CNS) in systemic lupus erythematosus (SLE) is an important source of morbidity and mortality. S100β has been considered…
Abstract Number: 1108 • 2013 ACR/ARHP Annual Meeting
Methylphenidate Improves Concentration, Energy and Mood In Fibromyalgia
Robert S. Katz¹, Hannah Bond² and Frank Leavitt³, ¹Rush Medical College, Chicago, IL, ²Rheumatology Associates, Chicago, IL, ³Rush University Medical Center, Chicago, IL
Background/Purpose: Central nervous system stimulants such as methylphenidate appear to have short term benefits for naming speed and cognitive functioning in fibromyalgia (FMS). Methylphenidate quickly…
Abstract Number: 2644 • 2012 ACR/ARHP Annual Meeting
Functional Magnetic Resonance Imaging of Working Memory in Fibromyalgia: Support for a “Competing Demands” Theory of Cognitive Function in Chronic Pain
Anson E. Kairys¹, Gabriela Ramirez¹, Eric Ichesco², Johnson P. Hampson², Richard E. Harris², Daniel J. Clauw³, Tobias Schmidt-Wilcke² and Jennifer M. Glass⁴, ¹Department of Anesthesiology, Chronic Pain and Fatigue Research Center, University of Michigan, Ann Arbor, MI, ²Anesthesiology, University of Michigan, Ann Arbor, MI, ³Anesthesiology/Internal Medicine (Rheum), University of Michigan, Ann Arbor, MI, ⁴Psychiatry, University of Michigan, Ann Arbor, MI
Background/Purpose: The primary symptom of fibromyalgia (FM) is chronic widespread pain; however, patients report additional symptoms including decreased concentration and memory. Deficits are seen mainly…
Abstract Number: 1878 • 2012 ACR/ARHP Annual Meeting
Cognitive Manifestations of Fibromyalgia and Lupus
Robert S. Katz and Frank Leavitt, Rush University Medical Center, Chicago, IL
Background/Purpose: Similar cognitive complaints for patients with fibromyalgia and systemic lupus erythematosus (SLE) have been reported; however, inherently different deficits can share superficial similarities. The…
Abstract Number: 1451 • 2012 ACR/ARHP Annual Meeting
Estrogen Receptor Alpha Deficiency Protects Against Cognitive Defects in Murine Lupus
Melissa A. Cunningham¹, Osama S. Naga², Heather A. Boger³, Ann-Charlotte E. Granholm-Bentley³ and Gary S. Gilkeson⁴, ¹Med/Rheumatology, MUSC, Charleston, SC, ²Medicine/Rheumatology, Medical University of South Carolina, Charleston, SC, ³Neuroscience, Medical University of SC, Charleston, SC, ⁴Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, SC
Background/Purpose: Up to 80% of SLE patients have cognitive defects or affective disorders. The mechanism of CNS injury responsible for cognitive impairment is unknown. Anti-dsDNA…
Abstract Number: 611 • 2012 ACR/ARHP Annual Meeting
Impaired Diffusion Tensor Imaging Findings in the Corpus Callosum and Cingulum May Underlie Impaired Learning and Memory Abilities in Systemic Lupus Erythematosus
Daphna Paran¹, Elissa Ash², Ira Litinsky¹, Valerie Aloush¹, Marina Anouk¹, Dan Caspi³, Talma Hendler⁴ and Irit Shapira-Lichter⁴, ¹Rheumatology, Tel Aviv Sourasky Medical Ctr, Tel-Aviv University, Tel Aviv, Israel, ²Neurology, Tel Aviv Sourasky Medical Ctr, Tel-Aviv University, Tel Aviv, Israel, ³Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ⁴Functional Brain Center, Wohl Institute for Advanced Imaging, Tel-Aviv Sourasky Medical Ctr, Tel-Aviv University, Tel Aviv, Israel
Background/Purpose: Memory impairment is prevalent in systemic lupus erythematosus (SLE), however the pathogenesis is unknown. In a previous functional Magnetic Resonance Imaging (MRI) study we…
Abstract Number: 304 • 2012 ACR/ARHP Annual Meeting
Burden of Childhood Central Nervous System Vasculitis: Identifying High Risk Factors for Poor Cognitive Outcome
Peter J. Gowdie¹, Marinka Twilt¹, Pascal N. Tyrrell¹, Robyn Westmacott², Tania Cellucci¹, Shehla Sheikh¹, Nick Blancette¹ and Susanne M. Benseler¹, ¹Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ²Psychology, The Hospital for Sick Children, Toronto, ON, Canada
Background/Purpose: Childhood primary angiitis of the CNS (cPACNS) is an increasingly recognized, reversible cause of severe neurological and psychiatric deficit such as stroke, refractory seizures…
Abstract Number: 281 • 2012 ACR/ARHP Annual Meeting
The Pediatric Automated Neuropsychological Assessment Metrics – Reproducibility and Responsive to Change in Cognition in Childhood-Onset Lupus
Patricia Vega-Fernandez¹, Marisa S. Klein-Gitelman², Jessica Hummel³, Erin C. Thomas⁴, Jennifer L. Huggins⁵, Frank Zelko⁶, Tresa Roebuck-Spencer⁷, Jun Ying⁸ and Hermine Brunner⁵, ¹Division of Rheumatology, Cincinanti Children's Hospital Medical Center, Cincinnati, OH, ²Division of Rheumatology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, ³Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁴Division of Rheumatology, Anne & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, ⁵Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁶Pediatric Neuropsychology Service, Children's Memorial Hospital, Chicago, IL, ⁷Center for the Study of Human Operator Performance, University of Oklahoma, Norman, OK, ⁸Medicine-Internal Medicine-General Medicine, University of Cincinnati, Cincinnati, OH
Background/Purpose: The Childhood-onset Systemic Lupus Erythematosus (cSLE) Neuropsychological Battery (AC&R 2010; 62: 1029-33) was introduced to standardize neuropsychological testing (NPT), specifically probing the domains Attention,…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].