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Abstracts tagged "Cerebrovascular disease"

  • Abstract Number: 024 • Pediatric Rheumatology Symposium 2023

    Effects of Corticosteroids on Central Nervous System Microvascular Properties Assessed by Neuroimaging

    Mark DiFrancesco, Ekemini Ogbu, Catherine Robben, Jennifer Huggins and Hermine Brunner, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose: Prior research suggests that microvascular (MV) changes might be a biomarker for central nervous system (CNS) involvement of patients with systemic lupus erythematosus (SLE).…
  • Abstract Number: 1127 • ACR/ARHP Annual Meeting 2018

    Risk of Stroke Among Patients with Gout in Taiwan: A Nationwide Population Study

    Ping-Han Tsai and Chang-Fu Kuo, Division of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Taoyuan, Taiwan

    Background/Purpose: To determine whether the Taiwanese patients with gout have a higher risk of stroke.Methods: Using the National Health Insurance database, we identified a cohort…
  • Abstract Number: 2169 • ACR/ARHP Annual Meeting 2018

    Temporal Trends in Mortality in Patients Hospitalized for Cerebrovascular Events with Psoriatic Arthritis: Data from the Healthcare Cost and Utilization Project from 2010-2014

    Shraddha Jatwani1, Karan Chugh2, Karan Jatwani3, Stuthi Perimbeti4, Vivek Modi5, Jasleen Kaur6 and Rakesh K Sharma7, 1Department of Internal Medicine, Division of Rheumatology, Henry Ford Allegiance Health, Jackson, MI, 2Division of Pulmonary, Critical Care & Sleep, Wayne State University/Detroit Medical Center, Detroit, MI, 3Department of Internal Medicine, Mount Sinai West - St Luke’s Hospital, New York, NY, 4Department of Internal Medicine, Mount Sinai West - St Luke’s Hospital,, NEW YORK, NY, 5Department of Internal Medicine, Mount Sinai West - St Luke’s Hospital,, New York, NY, 6Department of Internal Medicine, Wayne State University/Detroit Medical Center, Detroit, MI, 7Department of Medicine, Postgraduate Institute of Medical Education & Research, Chandigarh, India

    Background/Purpose: Cerebrovascular disease risk in increased in patients of Psoriatic arthritis (PsA), as reported in the literature. Epidemiological studies to assesses average annual trends are…
  • Abstract Number: 2226 • ACR/ARHP Annual Meeting 2018

    Gout and the Risk of Incident Dementia in the Elderly: A Medicare Claims Study

    Jasvinder A. Singh1 and John Cleveland2, 1Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: The pursuit of a link between gout/hyperuricemia and dementia has led to contradictory results.  Most observational studies, including population-based studies, showed that hyperuricemia was…
  • Abstract Number: 2359 • ACR/ARHP Annual Meeting 2017

    Severity of Ischemic and Hemorrhagic Stroke in Patients with Rheumatoid Arthritis Compared with the General Population

    Mei-Yun Hsieh1, Chang-Fu Kuo2, Kuang-Hui Yu2, Shue-Fen Luo2,3 and Yen-Fu Chen2, 1Center for Big Data Analytics and Statistics, Chang Gung Memorial Hospital, Taoyuan, Taiwan, 2Division of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Taoyuan, Taiwan, 3Chang Gung Memorial Hospital, Taoyuan, Taiwan

    Background/Purpose: Rheumatoid arthritis (RA) patients are at higher risk of developing stroke but whether their risks for severe strokes are unknown. Methods: All patients with…
  • Abstract Number: 2759 • ACR/ARHP Annual Meeting 2017

    The Risk of Ischaemic Stroke in Primary APS Patients: A Prospective Study

    Massimo Radin1, Karen Schreiber2, Irene Cecchi3, Dario Roccatello4, Maria Jose Cuadrado5 and Savino Sciascia6, 1Department of Clinical and Biological Sciences, Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Turin, Italy, 2Department of Thrombosis and Haemophilia, Guy's and St Thomas' Hospital, London, United Kingdom., London, United Kingdom, 3Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Turin, Italy, 4Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin and S. Giovanni Bo, Turin, Italy, 5St Thomas Hospital, Lupus Research Unit, London, United Kingdom, 6Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Center of Research of Immunopathology and Rare Diseases- Coordinating Center of Piemonte and Valle d’Aosta Network for Rare Diseases, Department of Clinical and Biological Sciences, University of Turin, Italy, Torino, Italy

    Background/Purpose: The antiphospholipid syndrome(APS)is an autoimmune condition characterized by thrombosis and/or pregnancy morbidity andpersistent positivityfor antiphospholipid antibodies(aPL). The most common neurological manifestation of APS is…
  • Abstract Number: 2972 • ACR/ARHP Annual Meeting 2017

    Risk of Myocardial Infarction and Cerebrovascular Accident in Ankylosing Spondylitis: A General Population-Based Study

    Anthony So1, Jonathan Chan2, Eric C. Sayre3 and J. Antonio Avina-Zubieta3,4, 1University of British Columbia, Vancouver, BC, Canada, 2Rheumatology, University of British Columbia, Vancouver, BC, Canada, 3Arthritis Research Canada, Richmond, BC, Canada, 4Division of Rheumatology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada

    Background/Purpose: There is conflicting data on the risk of myocardial infarction (MI) and cerebrovascular accidents (CVA) in patients with Ankylosing Spondylitis (AS). This study attempts…
  • Abstract Number: 905 • ACR/ARHP Annual Meeting 2016

    Platelet Activation, As Measured By Plasma Soluble Glycoprotein VI, Is Not Associated with Disease Activity or Ischaemic Events in Giant Cell Arteritis

    Richard Conway1, Anne Madigan2, Laura Helbert3, Niamh Redmond4, Eimear Dunne5, Eamonn S. Molloy6, Dermot Kenny5 and Geraldine M. McCarthy7, 1CARD Newman Research Fellow, University College Dublin, Dublin, Ireland, 2Rheumatology, Mater Misericordiae University Hospital, Dublin 7, Ireland, 3Rheumatology, Mater Misericordiae University Hospital, Dublin, Ireland, 4UCD Clinical Research Centre, Dublin, Ireland, 5Molecular and Cellular Therapeutics, RCSI, Dublin 2, Ireland, 6Rheumatology, Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, St Vincent's University Hospital, Dublin, Ireland, 7Div of Rheumatology, Mater Misericordiae University Hospital, Dublin, Ireland

    Background/Purpose: Patients with Giant Cell Arteritis (GCA) have an increased risk of devastating cranial ischaemic complications including vision loss and stroke. The BSR guidelines recommend…
  • Abstract Number: 1483 • ACR/ARHP Annual Meeting 2016

    Elevated Anti-Cyclic Citrullinated Peptide Antibody Titer Is Associated with Increased Cardiovascular Risk

    Sarah A. Fantus1, Melissa R. Bussey2, Rochella A. Ostrowski3, Andrew Heisler1 and Kyle Carey4, 1Internal Medicine, Loyola University Medical Center, Maywood, IL, 2Division of Allergy, Immunology, and Rheumatology, Loyola University Medical Center, Maywood, IL, 3Rheumatology, Loyola University Medical Center, Maywood, IL, 4Clinical Research Office, Loyola University Chicago, Maywood, IL

    Background/Purpose: Rheumatoid arthritits (RA) patients have an increased risk of mortality from cardiovascular (CV) disease.  Proposed adaptation of CV risk score models in RA patients…
  • Abstract Number: 1993 • ACR/ARHP Annual Meeting 2016

    The Risk of Stroke in Patients with Rheumatoid Arthritis and the Association with Competing Adverse Events

    Yvette Meißner1, Adrian Richter2, Joern Kekow3, Hans Peter Tony4, Elke Wilden5, Angela Zink6,7, Joachim Listing2 and Anja Strangfeld7, 1Programme Area Epidemiology, German Rheumatism Research Center, Berlin, Germany, 2German Rheumatism Research Center, Berlin, Germany, 3University of Magdeburg, Clinic of Rheumatology, Magdeburg, Germany, 4Rheumatology / Clinical Immunology, University Hospital Würzburg, Würzburg, Germany, 5Rheumatologist, Köln, Germany, 6Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Berlin, Germany, 7Epidemiology, German Rheumatism Research Center, Berlin, Germany

    Background/Purpose: Patients with rheumatoid arthritis (RA) are at increased risk for infections, hospitalizations and cardiovascular (CV) events. The association of serious adverse events (SAE) with…
  • Abstract Number: 819 • ACR/ARHP Annual Meeting 2015

    Upregulation of Complement C3 and Alpha-2-Macroglobulin in Cerebrospinal Fluid of Neuropsychiatric Systemic Lupus Erythematosus

    Tomoyuki Asano1, Shuzo Sato1, Hiroko Kobayashi1, Yoshinobu Kariya2, Hiromi Ito2, Kyoka Hoshi2, Akioh Yoshihara3, Yoshikazu Ugawa3, Minoru Takahashi4, Hideharu Sekine4, Shunsei Hirohata5, Hiroshi Watanabe1, Hiromasa Ohira1 and Yasuhiro Hashimoto2, 1Gastroenterology and Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Japan, 2Biochemistry, Fukushima Medical University School of Medicine, Fukushima, Japan, 3Neurology, Fukushima Medical University School of Medicine, Fukushima, Japan, 4Immunology, Fukushima Medical University School of Medicine, Fukushima, Japan, 5Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Kanagawa, Japan

    Background/Purpose: Various autoantibodies have been identified in cerebrospinal fluids (CSF) of neuropsychiatric systemic lupus erythematosus (NPSLE). They are supposed to form immune complex with complement…
  • Abstract Number: 1752 • ACR/ARHP Annual Meeting 2015

    Characterization of Epitopes Identified with Cerebral Vasculature Injury

    Melissa Butts1, Jess Edison1, Christopher Tracy1, Brian Stout1, Huazhen Chen2 and Chantal Moratz2, 1Rheumatology, Walter Reed National Military Medical Center, Bethesda, MD, 2Medicine, Uniformed Services University School of Health Sciences, Bethesda, MD

    Background/Purpose: There is an association between natural antibodies, such as anti-phospholipid antibodies, and vasculature injury in stroke and in SLE models of systemic ischemic damage.  …
  • Abstract Number: 1972 • ACR/ARHP Annual Meeting 2015

    Cardiovascular and Cerebrovascular Disease and Social Deprivation in Patients with Giant Cell Arteritis

    Joanna Robson1, Amit Kiran2, Andrew Hutchings3, Joseph Maskell4, Nigel K Arden5, Willie Hamilton6, Bhaskar Dasgupta7,8 and Raashid Luqmani9, 1Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, University of Oxford, Oxford, United Kingdom, 2Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, United Kingdom, 3Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom, 4Faculty of Medicine, University of Southampton, Southampton, United Kingdom, 5Oxford NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, United Kingdom, 6Primary Care, University of Exeter, Exeter, United Kingdom, 7Southend University Hospital, Southend, United Kingdom, 8Rheumatology, Southend University Hospital, Essex, United Kingdom, 9Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom

    Background/Purpose: Giant cell arteritis (GCA) is the most common form of vasculitis in the UK, with an incidence of 2.2 cases per 10,000 person-years. Cerebrovascular…
  • Abstract Number: 3092 • ACR/ARHP Annual Meeting 2015

    Deficiency of Adenosine Deaminase Type II – Expanding the Clinical Spectrum

    Karyl Barron1, Amanda Ombrello2, Deborah Stone2, Patrycja Hoffmann2, Ivona Aksentijevich2,3, Qing Zhou2, Anne Jones2 and Daniel L. Kastner4, 1NIAID/NIH, Bethesda, MD, 2NHGRI/NIH, Bethesda, MD, 3Inflammatory Disease Section, National Human Genome Research Institute, Bethesda, MD, 4Inflammatory Disease Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD

    Background/Purpose: The deficiency of adenosine deaminase II (DADA2), first described in 2014, is an autosomal recessive disease caused by mutations in CECR1and is characterized by…
  • Abstract Number: 3159 • ACR/ARHP Annual Meeting 2015

    Systemic Lupus Erythematosus Is a Risk Factor for Young Stroke: A Population-Based Cohort Study

    Elizabeth V Arkema1, Elisabet Svenungsson2, Christopher Sjöwall3 and Julia F Simard4,5, 1Department of Medicine, Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden, 2Department of Medicine, Karolinska Insitutet, Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden, 3Department of Clinical and Experimental Medicine, Rheumatology/AIR, Linköping, Sweden, 4Division of Epidemiology, Health Research and Policy Department, and Division of Immunology & Rheumatology, Department of Medicine, Stanford School of Medicine, Stanford, CA, 5Clinical Epidemiology Unit, Dept of Medicine, Karolinska Institutet, Stockholm, Sweden

    Background/Purpose: Previous studies indicate that individuals with SLE have a high risk of stroke but have not investigated when the highest risk occurs. We aimed…
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