ACR Meeting Abstracts

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Abstracts tagged "Cardiovascular"

  • Abstract Number: 0487 • ACR Convergence 2024

    The Triglyceride to HDL Ratio, a Surrogate Marker of Insulin Resistance, Predicts All Cause and Cardiovascular Mortality in Rheumatoid Arthritis

    Jose Felix Restrepo Suarez1, Carlos Lorenzo1, Inmaculada Del rincon2 and Agustin Escalante1, 1UT Health San Antonio, San Antonio, TX, 2UT Health San Antonio, San Antonio

    Background/Purpose: The triglyceride to HDL cholesterol (TG/HDL) ratio, a recognized surrogate marker of insulin resistance, has emerged as a predictor of cardiovascular (CV) risk. However,…
  • Abstract Number: 0841 • ACR Convergence 2024

    Clinical and Biologic Predictors of Thrombosis in Persistently Antiphospholipid Antibody Positive Patients: Prospective Analysis of the International APS ACTION Clinical Database and Repository (“Registry”)

    Jonathan Thaler1, Michael Parides1, Danieli Andrade2, Diana Paredes-Ruiz3, Maria Tektonidou4, Vittorio Pengo5, Savino Sciascia6, Cecilia Nalli7, Guilherme Ramires de Jesús8, Paul Fortin9, Maria Efthymiou10, H Michael Belmont11, Michelle Petri12, Ricard Cervera13, Leslie Skeith14, TATSUYA ATSUMI15, Chary Lopez-Pedrera16, Yu Zuo17, David Branch18, Rohan Willis19, Nina Kello20, Zhuoli Zhang21, Esther Rodriguez-Almaraz22, Bahar Artim Esen23, Jose Pardos-Gea24, Guillermo Pons-Estel25, Giulia Pazzola26, Hui Shi17, Ali Duarte-Garcia27, Medha Barbhaiya1, Cécile Yelnik28, Pierluigi Meroni29, Robert Roubey30, Maria Laura Bertolaccini31, Hannah Cohen32, Jacob Rand33 and Doruk Erkan1, and on behalf of APS ACTION, 1Hospital for Special Surgery, New York, NY, 2University of São Paulo, São Paulo, SP, Brazil, 3Autoimmune Diseases Research Unit. Biocruces Bizkaia Health Research Institute, Baracaldo, Spain, 4National and Kapodistrian University of Athens, Athens, Greece, 5Thrombosis Research Laboratory, Department of Cardio-Thoracic-Vascular Sciences and Public Health, University of Padova, Padova, Italy, 6University of Turin, Torino, Turin, Italy, 7ASST SPEDALI CIVILI DI BRESCIA, Brescia, Italy, 8Universidade do Estado do Rio de Janeiro, Rio De Janeiro, Brazil, 9Centre ARThrite - CHU de Québec - Université Laval, Quebec, QC, Canada, 10University College London, London, United Kingdom, 11NYU School of Medicine, New York, NY, 12Johns Hopkins University School of Medicine, Timonium, MD, 13Hospital Clinic de Barcelona, Barcelona, Spain, 14University of Calgary, Calgary, ON, Canada, 15Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, 16IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Andalucia, Spain, 17University of Michigan, Ann Arbor, MI, 18University of Utah and Intermountain Healthcare, Salt Lake City, UT, 19University of Texas Medical Branch, Galveston, TX, 20Northwell Health, Brooklyn, NY, 21Peking University First Hospital, Beijing, China, 22Hospital Universitario 12 de Octubre, Madrid, Spain, 23Istanbul University, Istanbul Faculty of Medicine, Division of Rheumatology, Istanbul, Turkey, 24Vall d'Hebron University Hospital, Barcelona, Spain, 25CREAR, Rosario, Argentina, 26Rheumatology Unit, Azienda USL IRCCS di Reggio Emilia, Reggio Emilia, Italy, 27Mayo Clinic, Rochester, MN, 28lille university, Lille, France, 29IRCCS Istituto Auxologico Italiano 100%, Cusano Milanino, Milan, Milan, Italy, 30Division of Rheumatology, Allergy, and Immunology, University of North Carolina, Chapel Hill, NC, 31King's College London, London, United Kingdom, 32University College London Hospitals NHS Foundation Trust, London, United Kingdom, 33Weill Cornell Medical Center, Bronx, NY

    Background/Purpose: There is a lack of high-quality data to inform risk-stratified long-term thrombosis prevention strategies in patients with persistently positive antiphospholipid antibodies (aPL). The APS…
  • Abstract Number: 1133 • ACR Convergence 2024

    Relationship Between Nail Psoriasis Severity Index (NAPSI) and Cardiovascular Risk Assessed by Eight Cardiovascular Risk Calculators

    Maria F. Elizondo-Benitez1, Iris Jazmín Colunga Pedraza2, jose Ramon Azpiri-Lopez3, Dionicio Galarza-Delgado4, Jesus Cardenas-de la Garza5, Rosa Icela Arvizu-Rivera2, Andrea Guajardo Aldaco2 and Valeria Gonzalez-Gonzalez6, 1Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo León, Mexico, 2Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Mexico, 3Division of Cardiology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Mexico, 4UANL Hospital Universitario, Monterrey, Nuevo León, Mexico, 5Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico, 6Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Nuevo León, Mexico

    Background/Purpose: Psoriatic arthritis (PsA) is a chronic, inflammatory, and immune-mediated disease that affects up to 30% of psoriasis (PsO) patients. Nail psoriasis affects 80% of…
  • Abstract Number: 1567 • ACR Convergence 2024

    Systemic Sclerosis Is Associated with Sub-Clinical Abnormalities in Myocardial Energetics, Perfusion and Increased Fibrosis

    Chin Yit Soo1, Nicholas Jex2, Stefano Di Donato3, Lucy Elizabeth Thornton4, Vishal Kakkar5, Riccardo Bixio6, Raluca Tomoaia1, Thomas Anderton2, May Lwin2, Christel Kamani2, Amrit Chowdhary2, Henry Procter1, Sharmaine Thirunavukarasu1, Sindhoora Kotha2, Marilena Giannoudi2, Eylem Levelt2, Sven Plein1, Francesco Delgado6 and Lesley-Anne Bissell7, 1Multidisciplinary Cardiovascular Research Centre and Biomedical Imaging Science Department, University of Leeds, Leeds, United Kingdom., Leeds, England, United Kingdom, 2Multidisciplinary Cardiovascular Research Centre and Biomedical Imaging Science Department, University of Leeds, Leeds, United Kingdom., Leeds, United Kingdom, 31. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Leeds, United Kingdom, 41. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Leeds, 5University of Leeds, Leeds, United Kingdom, 6Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom., Leeds, United Kingdom, 7Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Background/Purpose: Primary cardiac involvement in systemic sclerosis (SSc) is heterogenous, poorly defined and associated with significant cardiac morbidity and mortality. The underlying mechanism is not…
  • Abstract Number: 2038 • ACR Convergence 2024

    Nationwide Analysis of Adult Hospitalizations with Rheumatologic Conditions and Spontaneous Coronary Artery Dissection

    Maria Romero Noboa1, Husam El Sharu2, Diego Cornejo3, Rafaella Litvin4 and Almurtada Razok4, 1University of Alabama at Birmingham, Chicago, IL, 2East Carolina University, Greenville, NC, 3John H Stroger Hospital of Cook County, Chicago, 4John H Stroger Jr Hospital of Cook County, Chicago, IL

    Background/Purpose: Rheumatic diseases have a higher risk of cardiovascular events, particularly those related to atherothrombosis which represents the leading cause of premature mortality in most of…
  • Abstract Number: 2500 • ACR Convergence 2024

    Description of Patients with Refractory Kawasaki Disease at a Large Tertiary Center

    Jessica Nguyen1, Danielle Guffey2, Andrea Ramirez1, Jamie Lai3, Tiphanie Vogel1, S. Kristen Sexson Tejtel1, Cagri Yildirim-Toruner4 and Marietta DeGuzman1, 1Baylor College of Medicine, Houston, TX, 2Baylor College of Medicine, Houston, 3Baylor College of Medicine, The Woodlands, TX, 4Baylor College of Medicine/ Texas Children's Hospital, Houston, TX

    Background/Purpose: Kawasaki disease (KD) is the leading cause of acquired heart disease in developed countries due to the development of coronary artery aneurysms (CAAs). Intravenous…
  • Abstract Number: 0147 • ACR Convergence 2024

    Clinical Characteristics and Biomarkers Associated with Detectable High-Sensitivity Cardiac Troponin in Patients with Rheumatoid Arthritis

    Ilana Usiskin1, Mary Jeffway1, Feng Liu1, Nancy Shadick1, Michael Weinblatt2, Brittany Weber3 and Katherine Liao1, 1Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital/ Harvard Medical School, Waban, MA, 3Brigham and Women's Hospital, DEDHAM, MA

    Background/Purpose: General population-based cardiovascular (CV) risk estimators are known to underestimate CV risk in RA. High-sensitivity cardiac troponin T (hs-cTnT), typically measured during a work-up…
  • Abstract Number: 0497 • ACR Convergence 2024

    Relationship Between the Complement System and Subclinical Carotid Atherosclerosis in Patients with Rheumatoid Arthritis

    Adrián Quevedo-Rodríguez1, Marta Hernández-Díaz2, Dara Rodríguez-González22, Fuensanta Gomez-Bernal3, Juan Carlos Quevedo-Abeledo4, Agustín F González-Rivero2, Elena González López5, gonzalo Ocejo-Viñals5, Miguel Angel Gonzalez-Gay6 and ivan Ferraz-Amaro7, 1Hospital de Gran Canaria Doctor Negrin, Las Palmas de Gran Canaria, Spain, 2Hospital Universitario de Canarias, SANTA CRUZ DE TENERIFE, Spain, 3Hospital Universitario de Canarias, Santa Cruz de Tenerife, Canarias, Spain, 4Hospital Universitario de Gran Canaria Dr Negrín, Las Palmas de GC, Canarias, Spain, 5Department of Immunology, Marqués de Valdecilla University Hospital (HUMV), Santander, Spain, 6University of Cantabria, Fundación Jimenez Díaz, Madrid, Madrid, Spain, 7Rheumatology, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Canarias, Spain

    Background/Purpose: Patients with rheumatoid arthritis (RA) have an increased risk of cardiovascular (CV) events and CV mortality. Carotid subclinical atherosclerosis is independently associated with incident…
  • Abstract Number: 0849 • ACR Convergence 2024

    Effectiveness of Tocilizumab in Aortitis and Aneurysms Associated with Giant Cell Arteritis. Multicenter Open-label Study

    Adrián Martín-Gutiérrez1, Javier Loricera2, Carmen Secada Gómez3, Iñigo Hernández-Rodríguez4, Susana Romero Yuste5, Eugenio De Miguel6, Eva Galindez-Agirregoikoa7, ivan Ferraz-Amaro8, Julio Sánchez-Martín9, Patricia Moya Albarado10, Cristina Campos Fernández11, Fernando Lopez-Gutierrez12, Santos Castañeda13 and Ricardo Blanco-Alonso14, and the Tocilizumab in Giant Cell Arteritis Spanish Collaborative Group, 1Hospital Universitario Marques de Valdecilla, IDIVAL, Renedo de Piélagos, Cantabria, Spain, 2Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 3Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 4Complejo Hospitalario Universitario de Vigo, Vigo, Spain, 5Department of Rheumatology, University Hospital Complex of Pontevedra, Pontevedra, Spain, 6Hospital Universitario La Paz, Madrid, Spain, 7BASURTO UNIVERSITY HOSPITAL, BILBAO, Spain, 8Rheumatology, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Canarias, Spain, 9Hospital Universitario 12 de Octubre, Madrid, Spain, 10Hospital de San Pau, Barcelona, Spain, 11Escuela de Doctorado, Universidad Católica de Valencia San Vicente Mártir, Valencia, Spain, 12Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Cantabria, Spain, 13Hospital Universitario de la Princesa, Madrid, Spain, 14Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain

    Background/Purpose: Giant Cell Arteritis (GCA) was initially described involving mainly the extracranial branches of the carotid arteries. However, GCA also may involve the aorta (GCA-aortitis)…
  • Abstract Number: 1188 • ACR Convergence 2024

    High Risk of Stroke in Men with Joint Prosthesis Due to Osteoarthritis: The Prospective STRAMBO Study

    MAXIME AUROUX1, PAWEL SZULC2 and ROLAND CHAPURLAT1, 1Hospices Civls de Lyon, LYON, Rhone-Alpes, France, 2INSERM U1033, LYON, Rhone-Alpes, France

    Background/Purpose: Osteoarthritis (OA) and cardiovascular disease share risk factors. The impact of OA on cardiovascular and especially cerebrovascular outcomes is still debated. Our aim was to…
  • Abstract Number: 1579 • ACR Convergence 2024

    Exploring the Cardiovascular Complications of Pulmonary Arterial Hypertension in Individuals with Systemic Sclerosis

    Omar Mourad1, Saif Abu Baker1, Georges Khattar2, Jennifer Jdaidani3, Khalil El-Gharib3 and Ahmad Mustafa3, 1Staten Island University Hospital- Northwell Health, Staten Island, NY, 2Staten Island University Hospital, Staten Island, NY, 3Staten Island University Hospital- Northwell Health, Staten Island

    Background/Purpose: Systemic sclerosis (SS) is a complex autoimmune rheumatic disease characterized by immune-mediated activation of both innate and adaptive immunity. Pulmonary involvement, specifically pulmonary arterial…
  • Abstract Number: 2213 • ACR Convergence 2024

    Microvascular and Macrovascular Endothelial Dysfunction in Rheumatoid Arthritis

    Vanshika Sabharwal, and Dr Ashit syngle and Dr Inderjeet Verma, MMDU, Mullana, Ambala India and Healing Touch city clinic, Chandigarh, India, Chandigarh, Chandigarh, India

    Background/Purpose: RA is a chronic inflammatory disease associated with an excessive premature cardiovascular morbidity and mortality. Endothelial dysfunction is a significant contributor to CVD in…
  • Abstract Number: 2508 • ACR Convergence 2024

    The Impact of Lipid Profile Parameters on the Incidence of Major Adverse Cardiovascular Events in Rheumatoid Arthritis Patients: A Single-arm Meta-Analysis

    Nouman Shafique1, Ali Raza Khan2, Abdul Qadeer2, zaigham Shaukat2 and Rabia Iqbal2, 1AdventHealth Orlando, Orlando, FL, 2Nishtar Medical University, Multan, Punjab, Pakistan

    Background/Purpose: Cardiovascular diseases (CVD) are a significant cause of morbidity and mortality among patients with rheumatoid arthritis (RA), accounting for nearly 40% of their mortality.…
  • Abstract Number: 0156 • ACR Convergence 2024

    Psoriasis and Psoriatic Arthritis Are Independent Risk Factors for Non-Fatal Cardiovascular Admissions in Transition-Age Young Adults

    Anurag Goel1, Joshua Tanzer2 and Vinit Gilvaz3, 1The Warren Alpert Medical School of Brown University, Providence, RI, 2Lifespan Biostatistics, Epidemiology, Research Design, and Informatics Core, Providence, RI, 3The Warren Alpert Medical School of Brown University, East Providence, RI

    Background/Purpose: Psoriasis (PsO) and psoriatic arthritis (PsA) are closely linked inflammatory conditions that can affect both children and adults. In children, these diseases are associated…
  • Abstract Number: 0503 • ACR Convergence 2024

    Use of Janus Kinase Inhibitors Before and After European Medicines Agency Safety Recommendations

    Patrick-Pascal Strunz1, Linus Maximilian Risser2, Matthias Englbrecht3, Torsten Witte4, Matthias Froehlich5, Marc Schmalzing6, Michael Gernert7, Peter Bartz-Bazzanella8, Sebastian Hueper9, Cay von Der Decken10, Georg Gauler11, Susanna Spaethling-Mestekemper12, Christoph Kuhn13, Kirsten Karberg14, Wolfgang Vorbrueggen15, Martin Welcker16 and Stefan Kleinert17, 1University hospital of Wuerzburg, Wuerzburg, Germany, 2Hannover Medical School, Hannover, Germany, 3Freelance Healthcare Data Scientist, Eckental, 4Dept of Immunology and Rheumatology, Hannover, Germany, 5Uniklinikum Wuerzburg, Medizinische Klinik II, Wuerzburg, Germany, 6University Hospital Wuerzburg, Würzburg, Germany, 7Medicine II, Division Rheumatology/Clinical Immunology, University Hospital of Wuerzburg, Wuerzburg, 8Rhein-Maas Klinikum, Wuerselen, Germany, 9Praxis für Rheumatologie und Osteologie, Hildesheim, Germany, 10Klinik für Internistische Rheumatologie, Rhein-Maas-Klinik Wuerselen, Würselen, 11rheumapraxis, Osnabrück, Germany, 12Rheumapraxis Muenchen, Muenchen, Germany, 13Praxis für Rheumatologie, Karlsruhe, Germany, 14Rheumatologisches Versorgungszentrum Steglitz, Berlin, Germany, 15RheumaDatenRhePort GbR, Wuerselen, Germany, 16Medizinisches Versorgungszentrum für Rheumatologie Dr. M. Welcker GmbH, Planegg, Germany, 17Praxisgemeinschaft Rheumatologie - Nephrologie (PGRN), Erlangen, Germany

    Background/Purpose: Safety recommendations for Janus kinase inhibitors (JAKi) issued by the European Medical Agency (EMA) in 2023 could potentially influence prescription patterns for drugs used…
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