Abstracts tagged "Cardiovascular disease"

Abstract Number: L01 • 2018 ACR/ARHP Annual Meeting
New Cardiovascular Events in Patients with Gout Treated with Xanthine-Oxidase Inhibitors: An Inception Cohort Analysis
Neus Quilis¹, Laura Ranieri², Jose Sanchez-Paya² and Mariano Andrés², ¹Hospital Universitario del Vinalopó, Elche, Spain, ²Hospital General Universitario de Alicante-ISABIAL, Alicante, Spain
Background/Purpose: The recent CARES trial findings have contributed to the controversy around the development of cardiovascular (CV) events in gouty patients using febuxostat (FBX). In…
Abstract Number: L05 • 2018 ACR/ARHP Annual Meeting
Treatment-Naïve, Early Rheumatoid Arthritis Patients Demonstrate Reversible Abnormalities of Vascular Function on Cardiac MRI with RA Therapy with Preliminary Suggestion of Greater Improvement with Anti-TNF Compared to MTX/Conventional Therapy – a First, RCT Derived Longitudinal Study
Maya H. Buch¹, Bara Erhayiem², Graham Fent², Paul Baxter³, Elizabeth M.A. Hensor⁴, Adam McDiarmid², Peter Swoboda⁵, Ananth Kidambi², David Ripley², Pankaj Garg², Sarah Horton⁴, Raluca Bianca Dumitru⁴, Kamran Naraghi⁴, John Greenwood⁶, Paul Emery⁷, Sue Pavitt⁸ and Sven Plein², ¹Leeds Institute of Rheumatic & Musculosekeltal Medicine, University of Leeds & NIHR Biomedical Research Centre, Leeds, United Kingdom, ²Multidisciplinary Cardiovascular Research Centre, Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, Leeds, United Kingdom, ³Leeds Institute of Cardiovascular & Metabolic Medicine, University of Leeds, Leeds, United Kingdom, ⁴Leeds Institute of Rheumatic & Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁵Leeds Institute of Cardiovascular And Metabolic Medicine, University of Leeds, Leeds, United Kingdom, ⁶Leeds Institute of Cardiovascular And Metabolic Medicinee, University of Leeds, Leeds, United Kingdom, ⁷University of Leeds and NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom, ⁸Leeds School of Dentistry, University of Leeds, Leeds, United Kingdom
Background/Purpose: We previously reported abnormal cardiac MRI (CMR)-determined aortic stiffness in patients with early, treatment-naive RA1,2. We now report on whether this vascular stiffness is…
Abstract Number: 501 • 2018 ACR/ARHP Annual Meeting
Predictors of Change in Coronary Plaque Burden and Composition in Patients with Rheumatoid Arthritis
George Karpouzas¹, Sarah Ormseth², Elizabeth Hernandez² and Matthew Budoff³, ¹Division of Rheumatology, Harbor-UCLA Medical Center, Torrance, CA, ²Rheumatology, Harbor-UCLA Medical Center, Torrance, CA, ³Cardiology, Harbor-UCLA Medical Center, Torrance, CA
Background/Purpose: We previously reported higher prevalence, burden and more vulnerable occult coronary plaque composition in patients with rheumatoid arthritis (RA) compared to age and gender-matched…
Abstract Number: 752 • 2018 ACR/ARHP Annual Meeting
Prevalence and Predictors of Peripheral Vascular Disease in a Cohort of Systemic Lupus Erythematosus (SLE) Patients
Ida Dzifa Dey¹, Kelvin Acquaye², Alfred Yawson³, Kofi Agyabeng⁴, Ernest Yorke⁵, Vincent Boima⁶ and Charles Mate-Kole⁷, ¹Department of Medicine, Rheumatology Unit, School of Medicine and Dentistry,University of Ghana, Accra, Ghana, ²Department of Psychology, School of Medicine and Dentistry, Accra, Ghana, ³Department of Community Health, School of Medicine and Dentistry, Accra, Ghana, ⁴Department of Community Health, School of Medicine and Dentistry,University of Ghana, Accra, Ghana, ⁵Medicine, School of Medicine and Dentistry,University of Ghana, Accra, Ghana, ⁶School of Medicine and Dentistry,University of Ghana, Accra, Ghana, ⁷Department of Psychology, School of Medicine and Dentistry, University of Ghana, Accra, Ghana
Background/Purpose: Low Ankle-brachial index (ABPI) < 0.9 demonstrating peripheral vascular disease (PVD), is a marker of subclinical cardiovascular disease and it is an inexpensive and…
Abstract Number: 1290 • 2018 ACR/ARHP Annual Meeting
Systemic Inflammation and Atherosclerosis in Patients with Gout. Results from the NOR-Gout Study
Silvia Rollefstad¹, Till Uhlig^2,3, Lars Fridtjof Karoliussen³, Hilde B. Hammer⁴ and Anne Grete Semb⁵, ¹Preventive Cardio-Rheuma clinic, Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²University of Oslo, Oslo, Norway, ³Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁴Dept. of Rheumtology, Diakonhjemmet Hospital, Oslo, Norway, ⁵Preventive Cardio-Rheuma clinic, Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
Systemic inflammation and atherosclerosis in patients with gout. Results from the NOR-Gout studyBackground/Purpose: The association between gout and cardiovascular disease (CVD) is well known, whereas…
Abstract Number: 1862 • 2018 ACR/ARHP Annual Meeting
Exploring the Lipid Paradox Theory in Rheumatoid Arthritis: Very Low Circulating Low-Density Lipoprotein Concentration Levels Are Associated with Pro-Atherogenic Biomarkers
Jon T. Giles¹, Cecilia P. Chung², Mary Chester-Wasko³, Mike Centola⁴, Jenny Van Eyk⁵, Justyna Fert-Bober⁵, Amy Kao⁶, Annette M. Oeser⁷, C. Michael Stein² and Joan Bathon⁸, ¹Medicine/Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ²Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, ³Allegheny Health Network, Pittsburgh, PA, ⁴Haus Bioceuticals, Inc, Oklahoma City, OK, ⁵Cedars-Sinai Medical Center, Los Angeles, CA, ⁶Biogen, Cambridge, MA, ⁷Vanderbilt University Medical Center, Nashville, TN, ⁸Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY
Background/Purpose: Rheumatoid arthritis (RA) patients with very low levels of circulating low density lipoprotein cholesterol (LDL-C) have been reported to be at particularly high risk…
Abstract Number: 2771 • 2018 ACR/ARHP Annual Meeting
Current Practice of Cardiovascular Risk Assessment in Giant Cell Arteritis: A Single Center Study
Mohammed Bari¹, Anthony Ocon², Mohamed Tageldin¹, Mirrah Mumtaz¹, Muhammad Saad Shaukat¹, Paul Feustel¹, Ruben Peredo², Peter C. Grayson³ and Shubhasree Banerjee^1,4,5, ¹Albany Medical Center, Albany, NY, ²Medicine, Albany Medical Center, Albany, NY, ³National Institute of Arthritis, Musculoskeletal and Skin Disease, National Institutes of Health, Bethesda, MD, ⁴The Center for Rheumatology, Albany, NY, ⁵Systemic Autoimmunity Branch, NIAMS, NIH, Bethesda, MD
Background/Purpose: Giant cell arteritis (GCA) is a large vessel vasculitis affecting individuals over 50 years of age. Multiple epidemiological studies have determined increased risk of…
Abstract Number: 503 • 2018 ACR/ARHP Annual Meeting
Waist Circumference Based Abdominal Obesity Versus Body Mass Index in Rheumatoid Arthritis: Influence on the Risk of Diabetes and Cardiovascular Disease
Gulsen Ozen¹, Sofia Pedro² and Kaleb Michaud^1,2, ¹Rheumatology, University of Nebraska Medical Center, Omaha, NE, ²FORWARD, The National Databank for Rheumatic Diseases, Wichita, KS
Background/Purpose: Adipose tissue deposited around the mesentery is highly associated with insulin resistance and cardiovascular disease (CVD). Compared to BMI, waist circumference (WC) has been…
Abstract Number: 777 • 2018 ACR/ARHP Annual Meeting
Electrocardiographic Abnormalities Are Associated with the Occurrence of Strokes in Systemic Lupus Erythematosus
Thania Perez¹, Christopher Depender², Jianhua Li³ and Laura Geraldino-Pardilla⁴, ¹Columbia University, College of Physicians & Surgeons, New York, NY, ²Medicine/Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ³Department of Biomedical Informatics, Columbia University Medical Center, New York, NY, ⁴Division of Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY
Electrocardiographic Abnormalities Are Associated with the Occurrence of Strokes in Systemic Lupus Erythematosus Background/Purpose: Systemic lupus erythematosus (SLE) patients have a 10-fold higher risk for…
Abstract Number: 1337 • 2018 ACR/ARHP Annual Meeting
Myocardial Fatty Acid Metabolism and Perfusion Mismatch in Scintigraphy Predicts Worse Prognosis in Clinically Amyopathic Dermatomyositis
Harunobu Iida¹, Hironari Hanaoka¹, Kana Ishimori², Tomofumi Kiyokawa¹, Yukiko Takakuwa¹ and Kimito Kawahata¹, ¹Division of Rheumatology and Allergology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan, ²Division of Rheumatology and Allergy, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan
Background/Purpose: Clinically amyopathic dermatomyositis (CADM) patients are frequently manifested by rapidly progressive interstitial lung disease (ILD) and associated with a poor prognosis. Recently cardiac involvement…
Abstract Number: 1880 • 2018 ACR/ARHP Annual Meeting
Cardiovascular (CV) Risk Factors and Atherosclerotic CV Events Among Incident Cases of Systemic Sclerosis: Results from a Population Based Cohort (1980-2016)
Avneek Singh Sandhu¹, Reto Kurmann², Cynthia S. Crowson³, Rekha Mankad², Eric L. Matteson⁴, Thomas Osborn¹, Kenneth J. Warrington⁵ and Ashima Makol¹, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Cardiovascular Diseases, Mayo Clinic College of Medicine and Science, Rochester, MN, ³Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, MN, ⁴Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN, ⁵Rheumatology, Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, MN
Background/Purpose: Cardiac involvement, due to impairment of coronary microcirculation and myocardial fibrosis, affects prognosis in individuals with SSc, and represents one of the leading causes…
Abstract Number: 2802 • 2018 ACR/ARHP Annual Meeting
Risk of Ischemic Stroke in Veterans with Systemic Sclerosis: A Nationwide Cohort Study
David Ying^1,2, Milena Gianfrancesco¹, Laura Trupin¹, Jinoos Yazdany¹, Eric Greidinger^3,4 and Gabriela Schmajuk^2,5, ¹Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ²San Francisco VA Medical Center, San Francisco, CA, ³Medicine/Rheumatology, University of Miami Miller School of Medicine, Miami, FL, ⁴Miami VA Medical Center, Miami, FL, ⁵Medicine/Rheumatology, University of California - San Francisco, San Francisco, CA
Background/Purpose: Previously thought to involve primarily the microvasculature, systemic sclerosis (SSc) has been increasingly linked to macrovascular disease. Cardiovascular and cerebrovascular disease are responsible for…
Abstract Number: 504 • 2018 ACR/ARHP Annual Meeting
Views of Primary Care Physicians and Rheumatologists Regarding Screening and Management of Hyperlipidemia Among Patients with Rheumatoid Arthritis
Iris Navarro-Millán^1,2, Anna Cornelius-Schecter², Ronan O'Beirne³, Melanie Morris³, Susan Goodman¹, Andrea Cherrington³, Liana Fraenkel⁴, Jeffrey R. Curtis³ and Monika M. Safford², ¹Hospital for Special Surgery, New York, NY, ²Weill Cornell Medicine, New York, NY, ³University of Alabama at Birmingham, Birmingham, AL, ⁴Yale University, New Haven, CT
Background/Purpose: Screening and management of hyperlipidemia in rheumatoid arthritis (RA) is suboptimal, despite RA patients’ high risk for cardiovascular disease (CVD) mortality. Our purpose was…
Abstract Number: 788 • 2018 ACR/ARHP Annual Meeting
Clinical and Echocardiographic Associates of All-Cause Mortality and Cardiovascular Outcomes in Patients with Systemic Sclerosis
Susanne Van Wijngaarden¹, Maaike Boonstra², Bas Bloem³, Daniela Cassani⁴, Felix Tanner⁴, Suzana Jordan⁵, Oliver Distler⁶, Martin Jan Schalij³, V. Delgado¹, J.J. Bax¹, Jeska de Vries-Bouwstra⁷ and Nina Ajmone Marsan¹, ¹Heart and Lung Center, Leiden University Medical Center, Leiden, Netherlands, ²Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Leiden University Medical Center, Leiden, Netherlands, ⁴University Heart Center, University Hospital Zurich, Zurich, Switzerland, ⁵Rheumatology, Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁶Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁷Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Cardiac events are an important cause of mortality in Systemic Sclerosis (SSc), but its diagnosis remains challenging. Left ventricular global longitudinal strain is a…
Abstract Number: 1512 • 2018 ACR/ARHP Annual Meeting
Reduction in Power Doppler Ultrasound Score with Tocilizumab Treatment Associates with Improvement in the Protective Profile of HDL in Patients with Rheumatoid Arthritis
Christina Charles-Schoeman¹, Gurjit Kaeley², Jennifer Wang³, Ani Shahbazian³, Jenny Brook⁴, David Elashoff⁴ and Veena K. Ranganath⁵, ¹Rheumatology, UCLA David Geffen School of Medicine, Los Angeles, CA, ²UF Health Jacksonville, Jacksonville, FL, ³University of California, Los Angeles, Los Angeles, CA, ⁴Department of Medicine Statistics Core, UCLA David Geffen School of Medicine, Los Angeles, CA, ⁵1000 VETERAN BLVD., RM 32-59, UCLA, Los Angeles, CA
Background/Purpose: Musculoskeletal ultrasound (MSUS) can detect synovitis by Power doppler (PDUS) and can predict erosive progression on xrays in rheumatoid arthritis (RA) patients. We previously…

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