Abstracts tagged "Cardiovascular disease"

Abstract Number: 475 • 2013 ACR/ARHP Annual Meeting
Alteration Of Aortic Distensibility Within 6 Months Of Treatment In RA Patients: An Observational Comparison Of Infliximab and Synthetic Dmards
Birgul Ay¹, Dilek Keskin², Goksal Keskin³ and Ayhan Dinc⁴, ¹Internal Medicine, DYB Research and Training Hospital, Ankara, Turkey, ²Immunology, DYB Research and Training Hospital, Ankara, Turkey, ³Internal Medicine and Clinical Immunology, DYB Research and Training Hospital, Ankara, Turkey, ⁴Rheumatology, Patio Clinic, Ankara, Turkey
Background/Purpose: The proximal aorta accounts for most of the global arterial stiffening and subsequent complications. Aortic stiffness can be demonstrated by changes in aortic dimensions…
Abstract Number: 359 • 2013 ACR/ARHP Annual Meeting
Tocilizumab Treatment Increases Left Ventricular Ejection Fraction and Decreases Left Ventricular Mass Index In Rheumatoid Arthritis Patients Without Cardiac Symptoms : Assessment By Cardiac Magnetic Resonance Imaging At 3.0 Tesla
Hitomi Kobayashi^1,2, Isamu Yokoe³, Hiroshi Sato², Yasuyuki Kobayashi⁴, Kihei Yoneyama⁵, Masaharu Hirano⁶ and Masami Takei⁷, ¹Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ²Rheumatology, Itabashi Chuo Medical Center, Tokyo, Japan, ³Nihon University School of Medicine, Tokyo, Japan, ⁴Radiology, St.Marianna University School of Medicine, Kawasaki, Japan, ⁵Cardiology, St.Marianna University School of Medicine, Kawasaki, Japan, ⁶Cardiology, Tokyo Medical Colleage, Tokyo, Japan, ⁷Division of Hematology and Rheumatology, NIhon University School of Medicine, Tokyo, Japan
Background/Purpose: Left ventricular (LV) dysfunction in rheumatoid arthritis (RA) may result, at least in part, from inflammation that may be regional and global. Therefore, therapies…
Abstract Number: 2221 • 2012 ACR/ARHP Annual Meeting
Major Adverse Cardiovascular Events Are More Common in Rheumatoid Arthritis Than in Psoriatic Arthritis and Are Associated with Different Risk Factors
Allen P. Anandarajah¹, Katherine C. Saunders², George W. Reed³, Alina U. Onofrei³, Jeffrey D. Greenberg⁴ and Christopher T. Ritchlin⁵, ¹Dept of Rheumatology, Univ of Rochester Medical Ctr, Rochester, NY, ²Corrona, LLC., Southborough, MA, ³University of Massachusetts Medical School, Worcester, MA, ⁴NYU Hospital for Joint Diseases, New York, NY, ⁵Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY
Background/Purpose: Rheumatoid Arthritis (RA) is associated with increased cardiovascular mortality and morbidity rates. Similarly several studies have reported an increased risk for cardiovascular events in…
Abstract Number: 1265 • 2012 ACR/ARHP Annual Meeting
Lipoprotein Subclass Particles and Small Vessel Elasticity As a Potential Marker for Early Atherosclerosis in Rheumatoid Arthritis: a Prospective, Controlled Study
Marty T. Mertens¹ and Elie Gertner², ¹Rheumatology, University of Minnesota, Minneapolis, MN, ²Section of Rheumatology, Regions Hospital and University of Minnesota Medical School, St. Paul, MN
Background/Purpose: Rheumatoid arthritis (RA) has increased rates of cardiovascular (CV) events. However, standard CV risk factors, such as routine lipid profiles, are not different in…
Abstract Number: 640 • 2012 ACR/ARHP Annual Meeting
Association of Body Weight with Cardiovascular Events in Systemic Lupus Erythematosus
George Stojan¹, Homa Timlin², Hong Fang³, Laurence S. Magder⁴ and Michelle Petri³, ¹Division of Rheumatology, Harvard Medical School- Beth Israel Deaconess Medical Center, Boston, MA, ²West Drayton, United Kingdom, ³Johns Hopkins University School of Medicine, Baltimore, MD, ⁴Department of Epidemiology and Public Health, University of Maryland, Baltimore, MD
Background/Purpose: Excessive body mass among healthy subjects carries an increased risk of subsequent cardiovascular (CV) events. In healthy subjects, the relationship between body mass index…
Abstract Number: 2180 • 2012 ACR/ARHP Annual Meeting
Coronary Flow Reserve and Asymmetric Dimethylarginine Levels: New Measurements for Identifying Subclinical Atherosclerosis in Patients with Primary Sjögren’s Syndrome
F. Atzeni¹, L. Boccassini¹, M.C. Signorello², MA Carrideo², L. Gianturco², V. De Gennaro Colonna³, L. Drago⁴, M. Turiel² and P. Sarzi-Puttini¹, ¹Rheumatology Unit, L. Sacco University Hospital of Milan, Milan, Italy, ²IRCCS Galeazzi Orthopedic Institute, University of Milan, Department of Health Technologies, Cardiology Unit,, Milan, Italy, ³Pharmacology Department, University of Milan, Milan, Italy, ⁴Laboratory Unit, IRCCS Galeazzi Orthopedic Institute, Department of Health Technologies, University of Milan, Milan, Italy
Background/Purpose: Clinical and biochemical data suggest that autoimmune diseases are associated with endothelial dysfunction and increased atherosclerosis. We have previously shown that asymmetric dimethylarginine (ADMA)…
Abstract Number: 1267 • 2012 ACR/ARHP Annual Meeting
Inflammatory Burden Predicts Progression of Carotid Plaque in Rheumatoid Arthritis: A 24-Month Longitudinal Analysis
Churl Hyun Im¹, Na Ri Kim¹, Jong Wan Kang¹, Young Ji Kim¹, Kyung Hye Kim¹, Eon Jeong Nam¹ and Young Mo Kang², ¹Internal Medicine (Rheumatology), Kyungpook National University School of Medicine, Daegu, South Korea, ²Department of Internal Medicine (Rheumatology), Kyungpook National University School of Medicine, Daegu, South Korea
Background/Purpose: Carotid atherosclerosis, which is associated with the increased risk of cardiovascular (CV) disease, is increased in rheumatoid arthritis (RA) patients. In our previous study,…
Abstract Number: 623 • 2012 ACR/ARHP Annual Meeting
Endothelial Microparticles As a Biomarker for Endothelial Dysfunction in Active Systemic Lupus Erythematosus
Ben Parker¹, Awal Zaki², M. Yvonne Alexander³ and Ian N. Bruce⁴, ¹Manchester Academic Health Science Centre, Arthritis Research UK Epidemiology Unit,, Manchester, United Kingdom, ²Manchester Academic Health Science Centre, Arthritis Research UK Epidemiology Unit, Manchester, United Kingdom, ³Healthcare Science Research Institute, Faculty of Science and Engineering, Healthcare Science Research Institute, Manchester Metropolitan University, Manchester, United Kingdom, ⁴Manchester Academic Health Science Centre, Arthritis Research UK Epidemiology Unit and NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester, United Kingdom
Background/Purpose: Systemic Lupus Erythematosus (SLE) is associated with an increased risk of clinical and subclinical cardiovascular disease (CVD) including endothelial dysfunction, in part due to…
Abstract Number: 2157 • 2012 ACR/ARHP Annual Meeting
Resveratrol Counters Pro-Atherogenic Effects of Systemic Lupus Erythematosus and Rheumatoid Arthritis Plasma On Cholesterol Efflux in Human Macrophages
Allison B. Reiss¹, Iryna Voloshyna¹, Ofek Hai¹, Michael J. Littlefield¹, Elise Belilos², Kristina B. Belostocki², Lois A. Bonetti³, Gary C. Rosenblum² and Steven E. Carsons⁴, ¹Medicine, Winthrop University Hospital, Mineola, NY, ²Rheumatology, Winthrop University Hospital, Mineola, NY, ³Rheum & Immun, Winthrop University Hospital, Mineola, NY, ⁴Div of Rheumatology, Winthrop University Hospital, Mineola, NY
Background/Purpose: Our group has demonstrated that resveratrol, a plant polyphenol, possesses atheroprotective properties, enhancing expression of reverse cholesterol transport (RCT) proteins. We have reported that Systemic…
Abstract Number: 1268 • 2012 ACR/ARHP Annual Meeting
Lipid Alterations and Measurement of Arterial Stiffness in Rheumatoid Arthritis
Marina Scolnik¹, Carla Saucedo², David A. Navarta³, Leandro Ferreyra Garrott², Erika Catay⁴, Maria L. Acosta Felquer⁵, Eliana Lancioni⁶, Cristian Quiroz³, Federica Varela Guidetti⁵, Zaida Bedran², Mirtha Sabelli⁴, Javier Rosa⁴, Maria Victoria Garcia⁴, Patricia M. Imamura⁵, Patricia Sorroche⁷, Jose Alfie⁸, Margarita Morales⁹, Gabriel Waisman⁹, Luis J. Catoggio¹ and Enrique Soriano¹, ¹Rheumatology Section, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ²Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ³Internal Medicine, Rheumatology Unit, Internal Medical Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁴Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁵Internal Medicine, Rheumatology Section, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁶Rheumatology Unit, Internal Medicine Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁷Central Laboratory , Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁸Internal Medicine, Hypertension Unit, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁹Hypertension Section, Internal Medicine Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disease. Increased arterial stiffness, an independent risk factor for premature coronary artery disease, has been reported in…
Abstract Number: 596 • 2012 ACR/ARHP Annual Meeting
Evolution of Atherosclerosis in Psoriatic Arthritis: Is the Former an Independent Inflammatory Process?
Roberta Ramonda¹, Massimo Puato², Valentina Modesti³, Mariagrazia Lorenzin⁴, Paola Frallonardo⁴, Augusta Ortolan⁴, Carla Campana³, Alessandro Lo Nigro³ and Leonardo Punzi⁵, ¹Rheumatology Unit, University of Padova, Padova, Italy, ²Department of Internal Medicine, University of Padova, Padova, Italy, ³Unit of Rheumatology, University of Padova, Padova, Italy, ⁴Rheumatology Unit, Department of Medicine, University of Padova, Padova, Italy, ⁵Clinical and Experimental Medicine, Rheumatology Unit - University of Padova, Padova, Italy
Background/Purpose: A non-invasive study focusing on the structural and functional properties of the carotid arteries was carried out in psoriatic arthritis (PsA) patients. Increased cardiovascular…
Abstract Number: 1720 • 2012 ACR/ARHP Annual Meeting
Cardiovascular Risk Management in Rheumatoid Arthritis Is Nurse Led Intervention Effective?
Fiona Niddrie¹ and Gabor AC Major², ¹Rheumatology, Bone and Joint Institute; Royal Newcastle Centre, Newcastle, Australia, ²Rheumatology, Bone&Joint Institute; Royal Newcastle Centre, Newcastle, Australia
Background/Purpose: There is a recognised increase in the incidence of heart disease in patients with rheumatoid arthritis (RA) Surveys of usual practice however frequently show…
Abstract Number: 1243 • 2012 ACR/ARHP Annual Meeting
Effect of Tocilizumab Treatment On Regional Left Ventricular Function, As Assessed by Cardiac Magnetic Resonance Imaging, in Rheumatoid Arthritis Patients without Cardiac Symptoms
Hitomi Kobayashi¹, Isamu Yokoe², Hiroshi Sato¹ and Yasuyuki Kobayashi³, ¹Rheumatology, Itabashi Chuo Medical Center, Tokyo, Japan, ²Nihon University School of Medicine, Tokyo, Japan, ³Radiology, St.Marianna University School of Medicine, Kawasaki, Japan
Background/Purpose: Rheumatoid arthritis (RA) is associated with an increased risk of congestive heart failure, possibly via shared mechanisms of inflammation. This study was undertaken to…
Abstract Number: 480 • 2012 ACR/ARHP Annual Meeting
Etanercept Induces A Significant Decrease of Oxidative Stress and Osteoprotegerin Compared with Sdmard in Patients with Rheumatoid Arthritis
Claire I. Daien¹, Anne-Marie Dupuy Gorce², Edith Pinot², Thibault Mura³, Jean-Paul Cristol², Bernard Combe⁴ and Jacques Morel⁵, ¹Department of Rheumatology, Lapeyronie Hospital, Montpellier, France, ²Biochemistry, Hopital Lapeyronie, Montpellier, France, ³CIC, Hopital Gui De Chauliac, Montpellier, France, ⁴Rheumatology, Hopital Lapeyronie, Montpellier, France, ⁵Dpartment of Rheumatology, Lapeyronie Hospital, Montpellier, France
Background/Purpose: TNF-inhibitors are known to decrease cardiovascular events in rheumatoid arthritis (RA) as compared with synthetic disease modifying anti-rheumatic drugs (sDMARD). However, mechanisms involved remain…
Abstract Number: 1702 • 2012 ACR/ARHP Annual Meeting
Tumor Necrosis Factor Blocking Agents Inhibit the Progression of Preclinical Atherosclerosis in Patients with Ankylosing Spondylitis
Alper M. van Sijl¹, Izhar C. van Eijk², Mike J.L. Peters³, Erik H. Serne³, Yvo M. Smulders⁴ and Mike T. Nurmohamed¹, ¹Rheumatology, Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, ²Rheumatology, VU University Medical Center, Amsterdam, Netherlands, ³Internal medicine, VU University Medical Center, Amsterdam, Netherlands, ⁴Internal Medicine, VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: Ankylosing spondylitis (AS) is associated with an increased cardiovascular (CV) risk that might be due to the chronic underlying inflammatory process. It is still…

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