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Abstracts tagged "Cardiovascular disease"

  • Abstract Number: 1437 • 2014 ACR/ARHP Annual Meeting

    Cholesterol Efflux Capacity of HDL and Coronary Atherosclerosis in Rheumatoid Arthritis

    Michelle J. Ormseth1, Patricia Yancey2, Suguru Yamamoto2, Annette M. Oeser1, Tebeb Gebretsadik3, Ayumi Shintani1, MacRae F. Linton1, Sergio Fazio1, Sean Davies1, L Jackson Roberts II1, Kasey C. Vickers1, Paolo Raggi4, Valentina Kon1 and C Michael Stein1, 1Vanderbilt University, Nashville, TN, 2Medicine, Vanderbilt University, Nashville, TN, 3Biostatistics, Vanderbilt University, Nashville, TN, 4Emory University, Atlanta, GA

    Background/Purpose: Cardiovascular (CV) risk is increased in patients with rheumatoid arthritis (RA), but not fully explained by traditional risk factors such as LDL and HDL…
  • Abstract Number: 1064 • 2014 ACR/ARHP Annual Meeting

    Unique Profile of Cardiovascular Risk Factors in Rheumatoid Arthritis High-Risk Populations with Insufficient Risk Control

    Ulf Müller-Ladner1, Stefan Kleinert2, Klaus Krüger3, Bianca Wittig4 and Rolf Hecker4, 1Rheumatologie und klinische Immunologie, Kerckhoff-Klinik GmbH, Abt. Rheumatologie und klinische Immunologie, Bad Nauheim, Germany, 2Rheumatologie, Praxisgemeinschaft Rheumatologie-Nephrologie, Rheumatologische Schwerpunktpraxis, Erlangen, Germany, 3Praxiszentrum St. Bonifatius, München, Germany, 4Abbvie Deutschland GmbH & Co. KG, Wiesbaden, Germany

    Background/Purpose More than 50% of premature deaths in patients with rheumatoid arthritis (RA) are due to cardiovascular disease (CVD). Both the cumulative burden of inflammation…
  • Abstract Number: 392 • 2014 ACR/ARHP Annual Meeting

    Neuroendocrine Hormone and Metabolic Peptide Levels in the Earliest Phases of Rheumatoid Arthritis – Do Free Fatty Acids Play a Role?

    Man Wai Tang1, Frieda A. Koopman2, Jan P.M. Visscher2, Marjolein J.H. de Hair2, Danielle M. Gerlag2,3 and Paul P. Tak2,4, 1Division of Clinical Immunology and Rheumatology & Department of Experimental Immunology, Academic Medical Center / University of Amsterdam, Amsterdam, Netherlands, 2Division of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, 3GlaxoSmithKline, Cambridge, United Kingdom, 4University of Cambridge, Cambridge and GlaxoSmithKline, Stevenage, United Kingdom

    Background/Purpose: Rheumatoid arthritis (RA) is a chronic autoimmune disease associated with several neuroendocrine hormones and metabolic peptides. The crosstalk between the hormones and the immune…
  • Abstract Number: 2936 • 2014 ACR/ARHP Annual Meeting

    Is Ankylosing Spondylitis a Risk Factor for Cardiovascular Diseases, and How Does These Risks Compare to Those in Rheumatoid Arthritis?

    Johan Askling1, Lennart Jacobsson2 and Jonas Eriksson1, 1Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, 2sahlrenska academy, gothenburg, Sweden

     Background/Purpose Patients with RA are at increased risk of cardiovascular (CV) diseases, including acute coronary syndromes (ACS), deep venous thromboembolism (DVT) and pulmonary embolism (PE),…
  • Abstract Number: 2103 • 2014 ACR/ARHP Annual Meeting

    Benefits of Early Onset of DAS28 (CRP) <2.6 on Physical Functioning, Quality of Life and Resource Use Among RA Patients in a Clinical Practice Setting

    E Alemao1, S Joo2, H Kawabata1, S Banerjee1, M Frits3, C Iannaccone3, N Shadick3 and M Weinblatt3, 1Bristol-Myers Squibb, Princeton, NJ, 2Bristol-Myers Squibb, Hopewell, NJ, 3Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Guidelines in RA recommend that treatment should be aimed at reaching a target of remission or low disease activity (LDA) as soon as possible,…
  • Abstract Number: 1413 • 2014 ACR/ARHP Annual Meeting

    The Prevalence of Renal Impairment in Patients with Rheumatoid Arthritis

    Marion Couderc Sr.1, Martin Soubrier2, Bruno Pereira3, Aurelien Tiple4, Melanie Gilson5, Bruno Fautrel6, Sophie Pouplin7, Emmanuelle Dernis Labous8, Laure Gossec9, Cécile Gaujoux-Viala10 and Maxime Dougados11, 1Chu G.Montpied, Clermont Ferrand, France, 2Rheumatology, CHU G.-Montpied, Clermont-Ferrand, France, 3Clinical research department, Clermont-Ferrand, France, 4Nephrology, CHU, Clermont-Ferrand, France, 5Rheumatology, CHu Grenoble, Grenoble, France, 6Rheumatology, Pitie Salpetriere Hospital, Paris, France, 7Rheumatology, Rouen University Hospital, Rouen, France, 8Rhumatologie, Ch Du Mans, Le Mans, France, 9Rheumatology, UPMC GRC08, Paris 06 University, Pitié Salpétrière Hospital, Paris, France, 10EA 2415, Montpellier I University, Nîmes University Hospital, Rheumatology Department, Nîmes, France, 11Université Paris René Descartes and Hôpital Cochin, Paris, France

    Background/Purpose: To assess the prevalence and associations of renal dysfunction in patients with rheumatoid arthritis (RA). Methods: COMEDRA is a French nationwide cross-sectional multicentre study…
  • Abstract Number: 1063 • 2014 ACR/ARHP Annual Meeting

    Management of Hyperlipidemia Among Patients with Rheumatoid Arthritis in the Primary Care Setting

    Kashif Jafri1, Lynne Taylor2, Nehal N. Mehta3, Melissa Nezamzadeh4, Joshua Baker5 and Alexis Ogdie6, 1Department of Medicine, University of Pennsylvania, Philadelphia, PA, 2Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, 3Division of Cardiovascular Medicine, University of Pennsylvania, Philadelphia, PA, 4University of Pennsylvania, Philadelphia, PA, 5Medicine/Rheumatology, University of Pennsylvania and Philadelphia VAMC, Philadelphia, PA, 6Rheumatology and Epidemiology, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Rheumatoid arthritis has been associated with an increased risk of cardiovascular morbidity and mortality.  It is unclear, however, whether this knowledge has translated into…
  • Abstract Number: 385 • 2014 ACR/ARHP Annual Meeting

    Validation of a Prognostic Model to Predict Structural Damage Assessed By X-Ray in Patients with RA Using MRI Data from a Clinical Trial

    EA Alemao1, S Joo2, S Banerjee1, P Allison3, P Emery4, M Weinblatt5 and Katherine Liao6, 1Bristol-Myers Squibb, Princeton, NJ, 2Bristol-Myers Squibb, Hopewell, NJ, 3University of Pennsylvania, Philadelphia, PA, 4University of Leeds, Leeds, United Kingdom, 5Brigham and Women's Hospital, Boston, MA, 6Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: We developed and validated a prognostic model for rapid radiographic progression (RRP) using X-ray data to identify RA patients (pts) at risk of structural…
  • Abstract Number: 2932 • 2014 ACR/ARHP Annual Meeting

    Increased Risk of Deep Vein Thrombosis and Pulmonary Embolism in Sjögren’s Syndrome: A General Population-Based Cohort Study

    Marko Yurkovich1, Hyon K. Choi2, Eric C. Sayre3, Kamran Shojania4 and J. Antonio Avina-Zubieta5, 1Department of Medicine, University of British Columbia, Vancouver, BC, Canada, 2Boston University School of Medicine, Boston, MA, 3Arthritis Research Centre of Canada, Richmond, BC, Canada, 4Rheumatology, University of British Columbia, Vancouver, BC, Canada, 5Rheumatology, Arthritis Research Centre of Canada, Richmond, BC, Canada

    Background/Purpose: There is limited data available on the risk of deep venous thrombosis (DVT) and pulmonary embolism (PE) in Sjögren's Syndrome (SjS). We estimated the…
  • Abstract Number: 2098 • 2014 ACR/ARHP Annual Meeting

    Genetic Variants of the NLRP3 Inflammasome Are Associated with Stroke in Patients with Rheumatoid Arthritis

    Alf Kastbom1, Lisbeth Ärlestig2 and Solbritt M. Rantapää-Dahlqvist3, 1Clinical and Experimental Medicine, Linköping University, Linköping, Sweden, 2Department of Public Health and Clinical Medicine/Rheumatology, Umeå University, Umeå, Sweden, 3Department for Public Health and Clinical Medicine/ Rheumatology, Umeå University, Umeå, Sweden

    Background/Purpose Inflammasomes are intra-cellular protein complexes important for the production of pro-inflammatory cytokines such as interleukin-(IL-)1β and IL-18.  Cardiovascular disease is over-represented in patients with…
  • Abstract Number: 1410 • 2014 ACR/ARHP Annual Meeting

    Low Rates of Cardiovascular Risk Factor Modification Among High-Risk Rheumatoid Arthritis Patients: Barrier to Cardiovascular Prevention Strategies?

    Kimberly P. Liang1, Rohit Aggarwal2, Juan (June) Feng3, Jason Lyons3, Heather Eng3, Stephen R. Wisniewski3, Melissa Saul4, Douglas P. Landsittel5, Douglas W. Chew1, Aryan Aiyer6 and Larry W. Moreland7, 1Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 2Medicine, University of Pittsburgh, Pittsburgh, PA, 3Epidemiology Data Center, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, 4Biomedical Informatics, University of Pittsburgh, School of Medicine, Pittsburgh, PA, 5Medicine, Biostatistics and Clinical and Translational Science, University of Pittsburgh, Center for Health Care Research Data Center, Pittsburgh, PA, 6Department of Medicine, Division of Cardiology, University of Pittsburgh Medical Center, Pittsburgh, PA, 7Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose:   Despite higher risk of cardiovascular disease (CVD) in rheumatoid arthritis (RA), systematic cardiovascular (CV) prevention strategies are lacking. Recent guidelines for CV risk…
  • Abstract Number: 945 • 2014 ACR/ARHP Annual Meeting

    Disease Remission Reduces Risk of Heart Failure in Rheumatoid Arthritis Patients Independent of Treatment Strategy

    Thomas Schau1, Michael Gottwald2, Christian Butter1 and Michael Zaenker3, 1Cardiology Dept., Immanuel Klinikum Bernau Heart Center Brandenburg, Bernau, Germany, 2Internal Med. Dept., Immanuel Klinikum Bernau, Rheumatology Center Northern Brandenburg, Bernau, Germany, 3Immanuel Klinikum Bernau, Rheumatology Center Northern Brandenburg, Bernau, Germany

    Background/Purpose Risk of heart failure (HF) is increased in patients with RA, however there is great variance in reported prevalence rates due to different diagnostic…
  • Abstract Number: 355 • 2014 ACR/ARHP Annual Meeting

    Increased Left Ventricular Mass Index and Decreased Ejection Fraction Are Associated with Disease Activity in Rheumatoid Arthritis Patients without Cardiac Symptoms; Comparison Between Non-Biologic and Biologic Dmards Treatment Groups, Using a Cardiac Magnetic Resonance Imaging

    Hitomi Kobayashi1, Yasuyuki Kobayashi2, Atsuma Nishiwaki3, Hirotake Inomata1, Noboru Kitamura1, Hidetake Shiraiwa3, Takamasa Nozaki3, Natsumi Ikumi4 and Masami Takei5, 1Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 2Radiology, St.Marianna University School of Medicine, Kawasaki, Japan, 3Nihon University School of Medicine, Tokyo, Japan, 4Division of Heamatology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 5Dept of Med Rheumatology, Nihon University School of Medicine, Itabashi Tokyo, Japan

    Background/Purpose Patients with rheumatoid arthritis (RA) experience an excess risk of congestive heart failure (CHF), but effects of disease-modifying anti-rheumatic drugs (DMARDs) on cardiac structure…
  • Abstract Number: 2889 • 2014 ACR/ARHP Annual Meeting

    The Association Between Changes in Inflammation and High Density Lipoprotein Cholesterol Efflux Capacity in Rheumatoid Arthritis

    K P Liao1, Martin Playford2, Michelle A. Frits3, Christine K. Iannaccone4, Jonathan S. Coblyn1, Michael E. Weinblatt5, Nancy A. Shadick6 and Nehal N. Mehta7, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 2National Heart, Blood, and Lung Institute, Bethesda, MD, 3Division of Rheumatology, Brigham and Women's Hospital, Boston, MA, 4Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 5Division of Rheumatology & Immunology, Brigham and Women's Hospital, Boston, MA, 6Brigham and Women's Hospital/Harvard University, Cambridge, MA, 7Division of Cardiovascular Medicine, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: High density lipoprotein (HDL) cholesterol efflux capacity measures the functional ability of HDL to remove cholesterol from atherosclerotic plaque. Low HDL efflux capacity is…
  • Abstract Number: 2084 • 2014 ACR/ARHP Annual Meeting

    Are Genetic Markers Associated with Myocardial Infarction in Patients with Early Rheumatoid Arthritis?

    Lisbeth Ärlestig1, Petros Zamout2, Lena Innala3, Eva Freyhult4, Solveig Wållberg Jonsson2 and Solbritt Rantapää-Dahlqvist2, 1Public Health & Clinical Medicine/Rheumatology, Institution of Public health and clinical medicine/ Rheumatology, University of Umeå, Rheumatology, Sweden, Umea, Sweden, 2Public Health & Clinical Medicine/Rheumatology, Institution of Public health and clinical medicine/ Rheumatology, University of Umeå, Rheumatology, Sweden, Umeå, Sweden, 3Rheumatology, Institution of Public health and clinical medicine/ Rheumatology, University of Umeå, Rheumatology, Sweden, Umeå, Sweden, 4Bioinformatics Infrastructure for Life Sciences, Uppsala, Sweden

    Background/Purpose Cardiovascular disease (CVD) are increased in patients with rheumatoid arthritis (RA). Traditional as well as disease related risk factors seem to contribute to the…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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