Abstracts tagged "Cardiovascular disease"

Abstract Number: 1608 • 2015 ACR/ARHP Annual Meeting
Protective Role of the Vitamin D Receptor Apai (rs7975232) Polymorphism Against Subclinical Atherosclerosis in Patients with Rheumatoid Arthritis from Northern Spain
Raquel López-Mejías¹, Fernanda Genre¹, Sara Remuzgo-Martínez¹, Gema Robledo², Begoña Ubilla¹, Veronica Mijares¹, Javier Llorca³, Montserrat Robustillo-Villarino⁴, Alfonso Corrales¹, Carlos González-Juanatey⁵, Jose A. Miranda-Filloy⁶, Trinitario Pina⁷, Ricardo Blanco⁷, Esther Vicente⁸, Juan José Alegre⁹, Cesar Magro¹⁰, Enrique Raya¹¹, Beatriz Tejera¹², Marco A Ramírez Huaranga¹³, Ivan Ferraz-Amaro¹², Santos Castañeda¹⁴, Javier Martín² and Miguel A. Gonzalez-Gay^1,15, ¹Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, Santander, Spain, ²Institute of Parasitology and Biomedicine López-Neyra, IPBLN-CSIC, Granada, Spain, ³Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), IDIVAL, Santander, Spain, ⁴Rheumatology Department, Hospital Universitario Doctor Peset, Valencia, Spain, ⁵Cardiology Division, Hospital Lucus Augusti, Lugo, Spain, ⁶Rheumatology Division, Hospital Lucus Augusti, Lugo, Spain, ⁷Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ⁸Rheumatology Department, Hospital Universitario la Princesa, IIS-Princesa, Madrid, Spain, ⁹Rheumatology, Rheumatology Department, Hospital Universitario Doctor Peset, Valencia, Spain, ¹⁰Rheumatology Department, Hospital Clínico San Cecilio, Granada, Spain, ¹¹Rheumatology, Hospital Clínico San Cecilio, Granada, Spain, ¹²Rheumatology Division, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, ¹³Rheumatology Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain, ¹⁴Rheumatology, H.U. La Princesa, Madrid, Spain, ¹⁵Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Background/Purpose: Several vitamin D receptor (VDR) polymorphisms have been associated with cardiovascular (CV) and autoimmune diseases. Carotid plaques are surrogate markers of severe atherosclerotic disease.…
Abstract Number: 2200 • 2015 ACR/ARHP Annual Meeting
Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking Clinical Database and Repository Cluster Analysis: Identification of Different Clinical Phenotypes Among Antiphospholipid Antibody-Positive Female Patients
Stephane Zuily¹, Cecilia B. Chighizola², DENIS WAHL¹, Pier Luigi Meroni³ and Doruk Erkan⁴, ¹CHU de Nancy, Vascular Medicine Division and Regional Competence Centre For Rare Vascular And Systemic Autoimmune Diseases; and UMR_S U1116 Research Unit, France, Nancy, France, ²Department of Clinical Sciences and Community Health, University of Milan, Istituto Auxologico Italiano, Cusano Milanino, Italy, ³University of Milan, Department of Clinical Sciences and Community Health, Division of Rheumatology, Gaetano Pini Institute, Milan, Italy, ⁴Barbara Volcker Center for Women & Rheumatic Disease, Hospital for Special Surgery, New York, NY
Background/Purpose: APS ACTION International Clinical Database and Repository was created to study the natural course of persistently antiphospholipid antibodies (aPL)-positive patients ± autoimmune disorders over…
Abstract Number: 3120 • 2015 ACR/ARHP Annual Meeting
The Prevalence, Incidence and Management of Hypertension, Diabetes and Hyperlipidemia in Psoriatic Arthritis, Psoriasis and Rheumatoid Arthritis
Kashif Jafri¹, Christie M. Bartels², Daniel Shin³ and Alexis Ogdie-Beatty⁴, ¹Department of Medicine, University of Pennsylvania, Philadelphia, PA, ²Medicine, Rheumatology, University of Wisconsin School of Medicine and Public Health, Madison, WI, ³University of Pennsylvania, Philadelphia, PA, ⁴Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Psoriasis, psoriatic arthritis (PsA), and rheumatoid arthritis (RA) are associated with an increased risk for cardiovascular disease (CVD). While management of traditional CVD risk…
Abstract Number: 473 • 2015 ACR/ARHP Annual Meeting
Methotrexate, Blood Pressure and Arterial Wave Reflection in Rheumatoid Arthritis
Leena R Baghdadi^1,2,3, Richard J Woodman², E Michael Shanahan⁴ and Arduino A Mangoni³, ¹Department of Family and Community Medicine, King Saud University, Riyadh, Saudi Arabia, ²Flinders Centre for Epidemiology and Biostatistics, Flinders University, Adelaide, Australia, ³Department of Clinical Pharmacology, Flinders University, Adelaide, Australia, ⁴Department of Rheumatology, Flinders University, Adelaide, Australia
Background/Purpose: Methotrexate (MTX) use has been associated with reduced cardiovascular morbidity and mortality in patients with rheumatoid arthritis (RA). Although MTX has anti-inflammatory effects, there…
Abstract Number: 1515 • 2015 ACR/ARHP Annual Meeting
Accounting for Rheumatoid Arthritis in the Determination of 10 Year Cardiovascular Risk
Rupal Chavda and Rochella A. Ostrowski, Rheumatology, Loyola University Medical Center, Maywood, IL
Background/Purpose: Patients with rheumatoid arthritis (RA) carry a higher risk for cardiovascular disease (CVD) independent of traditional risk factors. In this study, we set out…
Abstract Number: 1609 • 2015 ACR/ARHP Annual Meeting
Lack of Association Between ZHX2, Lepr, Gckr and ASCL1 and Carotid Intima-Media Thickness, Carotid Plaques and Cardiovascular Disease in Patients with Rheumatoid Arthritis
Raquel López-Mejías¹, Fernanda Genre¹, Sara Remuzgo-Martínez¹, Montserrat Robustillo-Villarino², Alfonso Corrales¹, Javier Llorca³, Carlos González-Juanatey⁴, Begoña Ubilla¹, Jose A. Miranda-Filloy⁵, Veronica Mijares¹, Trinitario Pina⁶, Ricardo Blanco⁶, Juan José Alegre², Marco A Ramírez Huaranga⁷, Maria D Mínguez Sánchez⁷, Carmen Gomez Vaquero⁸, Luis Rodriguez Rodriguez⁹, Benjamin Fernandez Gutierrez⁹, Alejandro Balsa¹⁰, Dora Pascual-Salcedo¹⁰, Francisco Lopez Longo¹¹, Patricia E. Carreira¹², Cesar Magro¹³, Enrique Raya¹⁴, Beatriz Tejera¹⁵, Ivan Ferraz-Amaro¹⁵, Esther Vicente¹⁶, Isidoro González-Alvaro¹⁶, Santos Castañeda¹⁷, Javier Martín¹⁸ and Miguel A. Gonzalez-Gay^1,19, ¹Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, Santander, Spain, ²Rheumatology Department, Hospital Universitario Doctor Peset, Valencia, Spain, ³Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), IDIVAL, Santander, Spain, ⁴Cardiology Division, Hospital Lucus Augusti, Lugo, Spain, ⁵Rheumatology Division, Hospital Lucus Augusti, Lugo, Spain, ⁶Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ⁷Rheumatology Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain, ⁸Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, ⁹Department of Rheumatology, Hospital Clínico San Carlos, Madrid, Spain, ¹⁰Department of Rheumatology, Hospital La Paz, Madrid, Spain, ¹¹Department of Rheumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain, ¹²Department of Rheumatology, Hospital Universitario 12 de Octubre, Madrid, Spain, ¹³Rheumatology Department, Hospital Clínico San Cecilio, Granada, Spain, ¹⁴Rheumatology, Hospital Clínico San Cecilio, Granada, Spain, ¹⁵Rheumatology Division, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, ¹⁶Rheumatology Department, Hospital Universitario la Princesa, IIS-Princesa, Madrid, Spain, ¹⁷Rheumatology, H.U. La Princesa, Madrid, Spain, ¹⁸Institute of Parasitology and Biomedicine López-Neyra, IPBLN-CSIC, Granada, Spain, ¹⁹Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Background/Purpose: Rheumatoid arthritis (RA) is a polygenic disease associated with accelerated atherosclerosis and increased cardiovascular (CV) mortality. Recent studies have identified the ZHX2 rs11781551 polymorphism…
Abstract Number: 2243 • 2015 ACR/ARHP Annual Meeting
Economic Burden of Controlled Gout, Uncontrolled Gout, and Gout Exacerbated By Common Comorbidities: Results from the 2012-2013 National Health and Wellness Survey
Robert Morlock¹, Natalia M. Flores², Kathy Annunziata³, Jonathan Chapnick⁴ and Javier Nuevo⁵, ¹4939 Directors Place, Ardea Biosciences, Inc., San Diego, CA, ²Kantar Health, Foster City, CA, ³Kantar Health, Princeton, NJ, ⁴Kantar Health, Horsham, PA, ⁵AstraZeneca, Madrid, Spain, Madrid, Spain
Background/Purpose: Gout is one of the most common forms of inflammatory arthritis and is caused by chronic high serum uric acid (sUA) levels (ie, hyperuricemia),…
Abstract Number: 3138 • 2015 ACR/ARHP Annual Meeting
Prognostic Role of Ventricular Ectopic Beats in Systemic Sclerosis
Giacomo De Luca¹, Silvia Laura Bosello¹, Francesca Gabrielli², Giorgia Berardi¹, Federico parisi¹, Manuela Rucco¹, Giovanni Canestrari¹, Leonarda Galiuto³, Filippo Crea³, Francesco Loperfido² and Gianfranco Ferraccioli¹, ¹Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy, ²Division of Heart Failure and Cardiac Rehabilitation, Catholic University - Rome, Rome, Italy, ³Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy
Background/Purpose: Heart involvement is common during Systemic Sclerosis (SSc), even if often clinically silent, and represents the leading cause of death in about one third…
Abstract Number: 35 • 2015 ACR/ARHP Annual Meeting
Rheumatoid Arthritis As a Risk Factor for Cardiovascular Events Following Hospitalized Pneumonia; A Population-Based Cohort Study
Mette Holland-Fischer¹, Ulrik Tarp², Reimar W. Thomsen³ and Mette Nørgaard³, ¹Department of Rheumatology, Aalborg University Hospital, Aalborg, Denmark, ²Department of Rheumatology, Aarhus University Hospital, AArhus, Denmark, ³Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark
Background/Purpose: Cardiovascular disease is a major cause of morbidity and mortality in patients with Rheumatoid Arthritis (RA). Patients with RA do also have an increased…
Abstract Number: 808 • 2015 ACR/ARHP Annual Meeting
Heritable Endotheliopathy and ApolipoproteinL1 Risk Traits in SLE
Ashira Blazer¹, Andrew Markham², Sara Rasmussen³, Jill P. Buyon⁴, H. Michael Belmont⁵, Shilpi Mehta-Lee⁶, Janet Nwaukoni⁴, Peter M. Izmirly⁷ and Robert Clancy⁴, ¹Division of Rheumatology, NYU School of Medicine, New York, NY, ²Medicine, New York University School of Medicine, New York, NY, ³Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ⁴Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ⁵Hosp for Joint Disease, New York, NY, ⁶Obstetrics and Gynecology, New York University School of Medicine, New York, NY, ⁷Rheumatology, NYU School of Medicine, New York, NY
Background/Purpose: With higher prevalence of renal and cardiovascular diseases (CVD), as well as HTN, African American (AA) SLE patients experience accelerated damage accrual and excess…
Abstract Number: 1523 • 2015 ACR/ARHP Annual Meeting
Ischemia Modified Albumin Levels in Rheumatoid Arthritis
Ali Ugur Uslu¹, Adem Kucuk², Sevket Balta³, Sevket Arslan⁴, Levent Tekin⁵, Sami Kucuksen⁶, Aysun Toker⁷ and Mehmet Kayrak⁸, ¹Internal Medicine, Eskisehir Military Hospital, Eskisehir, Turkey, ²Necmettin Erbakan U Meram T F, Necmettin Erbakan U Meram T F, Konya, Turkey, ³Cardiology, Eskisehir Military Hospital, Eskisehir, Turkey, ⁴Allergy and Clinical Immunology, Necmettin Erbakan University, Konya, Turkey, ⁵Physical Medicine and Rehabilitation, Beyhekim State Hospital, Konya, Turkey, ⁶MD, kONYA, Turkey, ⁷Biochemistry, Necmettin Erbakan University, Konya, Turkey, ⁸Necmettin Erbakan University, Division of Cardiology, Konya, Turkey
Background/Purpose: Cardiovascular diseases, among which atherosclerotic heart disease, are known to be one of the most important mortality and morbidity causes in patients with Rheumatoid…
Abstract Number: 1624 • 2015 ACR/ARHP Annual Meeting
Epigenetic Profiling of CD14+ and CD16+ Monocyte Subtypes in Rheumatoid Arthritis. Alterations Related to Cardiovascular Disease and Endothelial Dysfunction
Nuria Barbarroja^1,2, Patricia Ruiz-Limon¹, Carlos Perez-Sanchez¹, Yolanda Jiménez Gómez¹, MariCarmen Abalos-Aguilera¹, Pedro Segui³, Pilar Font¹, Ángeles Aguirre Zamorano¹, Jerusalem Calvo-Gutierrez¹, Rafaela Ortega¹, M. Carmen Castro Villegas¹, Eduardo Collantes-Estévez¹, Alejandro Escudero-Contreras¹ and Chary Lopez-Pedrera¹, ¹IMIBIC-Reina Sofia University Hospital, Rheumatology Unit, Cordoba, Spain, ²Rheumatology Unit, IMIBIC-Reina Sofia University Hospital, Cordoba, Spain, ³IMIBIC-Reina Sofia University Hospital, Radiology Unit, Cordoba, Spain
Background/Purpose: Monocytes play a key role in the pathogenesis of the cardiovascular disease (CVD). Three monocyte subsets have been described based on their CD14 and…
Abstract Number: 2270 • 2015 ACR/ARHP Annual Meeting
Cardiovascular Disease: The Hidden Risk in Persons with Rheumatoid Arthritis
Karen Soikkeli¹ and Glenn Ehresmann², ¹Graduate Nursing (Family Nurse Practitioner Program), Azusa Pacific University, Diamond Bar, CA, ²Rheumatology, Keck School of Medicine, University of Southern California-Los Angeles County Medical Center, Los Angeles, CA
Background/Purpose: Despite the fact that patients with rheumatoid arthritis (RA) experience a 50-60% increased risk of developing cardiovascular disease (CVD), substantial gaps remain in the…
Abstract Number: 3168 • 2015 ACR/ARHP Annual Meeting
How Strong Cardiovascular Risk Factor Are Gouty Tophi?
Rada Gancheva¹, Atanas Kundurdjiev², Mariana Ivanova¹, Todor Kundurzhiev³ and Zlatimir Kolarov⁴, ¹University Hospital "St. Iv. Rilski", Clinic of Rheumatology, Sofia, Bulgaria, ²University Hospital "Alexandrovska", Clinic of Nephrology, Sofia, Bulgaria, ³Medical University, Faculty of Public Health, Sofia, Bulgaria, ⁴Clinic of Rheumatology, University Hospital "St. Iv. Rilski", Clinic of Rheumatology, Sofia, Bulgaria
Background/Purpose: We have not found a study determining cardiovascular (CV) risk in the different stages of gout. This led us to use a complex multimodal…
Abstract Number: 36 • 2015 ACR/ARHP Annual Meeting
The Incidence of Cardiovascular Events in Patients with Rheumatoid Arthritis: a 15 Years Observational Cohort Study
Koen Laan¹, Rabia Agca^1,2, Alexandre E. Voskuyl³, Maarten Boers², Willem Lems² and Mike T. Nurmohamed^1,2, ¹Rheumatology, Amsterdam Rheumatology and immunology Center, Reade, Amsterdam, Netherlands, ²Rheumatology, Amsterdam Rheumatology and immunology Center, VU University medical center, Amsterdam, Netherlands, ³Rheumatology, Amsterdam Rheumatology and immunology Center, location VU University medical center, Amsterdam, Netherlands
Background/Purpose: The increased risk for cardiovascular (CV) disease in rheumatoid arthritis (RA) is well established. However, there are relatively few contemporary cohort studies with long…

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