ACR Meeting Abstracts

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Abstracts tagged "Cardiovascular disease"

  • Abstract Number: 1609 • 2015 ACR/ARHP Annual Meeting

    Lack of Association Between ZHX2, Lepr, Gckr and ASCL1 and Carotid Intima-Media Thickness, Carotid Plaques and Cardiovascular Disease in Patients with Rheumatoid Arthritis

    Raquel López-Mejías1, Fernanda Genre1, Sara Remuzgo-Martínez1, Montserrat Robustillo-Villarino2, Alfonso Corrales1, Javier Llorca3, Carlos González-Juanatey4, Begoña Ubilla1, Jose A. Miranda-Filloy5, Veronica Mijares1, Trinitario Pina6, Ricardo Blanco6, Juan José Alegre2, Marco A Ramírez Huaranga7, Maria D Mínguez Sánchez7, Carmen Gomez Vaquero8, Luis Rodriguez Rodriguez9, Benjamin Fernandez Gutierrez9, Alejandro Balsa10, Dora Pascual-Salcedo10, Francisco Lopez Longo11, Patricia E. Carreira12, Cesar Magro13, Enrique Raya14, Beatriz Tejera15, Ivan Ferraz-Amaro15, Esther Vicente16, Isidoro González-Alvaro16, Santos Castañeda17, Javier Martín18 and Miguel A. Gonzalez-Gay1,19, 1Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, Santander, Spain, 2Rheumatology Department, Hospital Universitario Doctor Peset, Valencia, Spain, 3Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), IDIVAL, Santander, Spain, 4Cardiology Division, Hospital Lucus Augusti, Lugo, Spain, 5Rheumatology Division, Hospital Lucus Augusti, Lugo, Spain, 6Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, 7Rheumatology Department, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain, 8Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 9Department of Rheumatology, Hospital Clínico San Carlos, Madrid, Spain, 10Department of Rheumatology, Hospital La Paz, Madrid, Spain, 11Department of Rheumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain, 12Department of Rheumatology, Hospital Universitario 12 de Octubre, Madrid, Spain, 13Rheumatology Department, Hospital Clínico San Cecilio, Granada, Spain, 14Rheumatology, Hospital Clínico San Cecilio, Granada, Spain, 15Rheumatology Division, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, 16Rheumatology Department, Hospital Universitario la Princesa, IIS-Princesa, Madrid, Spain, 17Rheumatology, H.U. La Princesa, Madrid, Spain, 18Institute of Parasitology and Biomedicine López-Neyra, IPBLN-CSIC, Granada, Spain, 19Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

    Background/Purpose: Rheumatoid arthritis (RA) is a polygenic disease associated with accelerated atherosclerosis and increased cardiovascular (CV) mortality. Recent studies have identified the ZHX2 rs11781551 polymorphism…
  • Abstract Number: 2243 • 2015 ACR/ARHP Annual Meeting

    Economic Burden of Controlled Gout, Uncontrolled Gout, and Gout Exacerbated By Common Comorbidities: Results from the 2012-2013 National Health and Wellness Survey

    Robert Morlock1, Natalia M. Flores2, Kathy Annunziata3, Jonathan Chapnick4 and Javier Nuevo5, 14939 Directors Place, Ardea Biosciences, Inc., San Diego, CA, 2Kantar Health, Foster City, CA, 3Kantar Health, Princeton, NJ, 4Kantar Health, Horsham, PA, 5AstraZeneca, Madrid, Spain, Madrid, Spain

    Background/Purpose: Gout is one of the most common forms of inflammatory arthritis and is caused by chronic high serum uric acid (sUA) levels (ie, hyperuricemia),…
  • Abstract Number: 3138 • 2015 ACR/ARHP Annual Meeting

    Prognostic Role of Ventricular Ectopic Beats in Systemic Sclerosis

    Giacomo De Luca1, Silvia Laura Bosello1, Francesca Gabrielli2, Giorgia Berardi1, Federico parisi1, Manuela Rucco1, Giovanni Canestrari1, Leonarda Galiuto3, Filippo Crea3, Francesco Loperfido2 and Gianfranco Ferraccioli1, 1Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy, 2Division of Heart Failure and Cardiac Rehabilitation, Catholic University - Rome, Rome, Italy, 3Institute of Cardiology, Catholic University of the Sacred Heart, Rome, Italy

    Background/Purpose: Heart involvement is common during Systemic Sclerosis (SSc), even if often clinically silent, and represents the leading cause of death in about one third…
  • Abstract Number: 35 • 2015 ACR/ARHP Annual Meeting

    Rheumatoid Arthritis As a Risk Factor for Cardiovascular Events Following Hospitalized Pneumonia; A Population-Based Cohort Study

    Mette Holland-Fischer1, Ulrik Tarp2, Reimar W. Thomsen3 and Mette Nørgaard3, 1Department of Rheumatology, Aalborg University Hospital, Aalborg, Denmark, 2Department of Rheumatology, Aarhus University Hospital, AArhus, Denmark, 3Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark

     Background/Purpose: Cardiovascular disease is a major cause of morbidity and mortality in patients with Rheumatoid Arthritis (RA). Patients with RA do also have an increased…
  • Abstract Number: 808 • 2015 ACR/ARHP Annual Meeting

    Heritable Endotheliopathy and ApolipoproteinL1 Risk Traits in SLE

    Ashira Blazer1, Andrew Markham2, Sara Rasmussen3, Jill P. Buyon4, H. Michael Belmont5, Shilpi Mehta-Lee6, Janet Nwaukoni4, Peter M. Izmirly7 and Robert Clancy4, 1Division of Rheumatology, NYU School of Medicine, New York, NY, 2Medicine, New York University School of Medicine, New York, NY, 3Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, 4Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, 5Hosp for Joint Disease, New York, NY, 6Obstetrics and Gynecology, New York University School of Medicine, New York, NY, 7Rheumatology, NYU School of Medicine, New York, NY

    Background/Purpose: With higher prevalence of renal and cardiovascular diseases (CVD), as well as HTN, African American (AA) SLE patients experience accelerated damage accrual and excess…
  • Abstract Number: 1523 • 2015 ACR/ARHP Annual Meeting

    Ischemia Modified Albumin Levels in Rheumatoid Arthritis

    Ali Ugur Uslu1, Adem Kucuk2, Sevket Balta3, Sevket Arslan4, Levent Tekin5, Sami Kucuksen6, Aysun Toker7 and Mehmet Kayrak8, 1Internal Medicine, Eskisehir Military Hospital, Eskisehir, Turkey, 2Necmettin Erbakan U Meram T F, Necmettin Erbakan U Meram T F, Konya, Turkey, 3Cardiology, Eskisehir Military Hospital, Eskisehir, Turkey, 4Allergy and Clinical Immunology, Necmettin Erbakan University, Konya, Turkey, 5Physical Medicine and Rehabilitation, Beyhekim State Hospital, Konya, Turkey, 6MD, kONYA, Turkey, 7Biochemistry, Necmettin Erbakan University, Konya, Turkey, 8Necmettin Erbakan University, Division of Cardiology, Konya, Turkey

    Background/Purpose:  Cardiovascular diseases, among which atherosclerotic heart disease, are known to be one of the most important mortality and morbidity causes in patients with Rheumatoid…
  • Abstract Number: 1624 • 2015 ACR/ARHP Annual Meeting

    Epigenetic Profiling of CD14+ and CD16+ Monocyte Subtypes in Rheumatoid Arthritis.  Alterations Related to Cardiovascular Disease and Endothelial Dysfunction

    Nuria Barbarroja1,2, Patricia Ruiz-Limon1, Carlos Perez-Sanchez1, Yolanda Jiménez Gómez1, MariCarmen Abalos-Aguilera1, Pedro Segui3, Pilar Font1, Ángeles Aguirre Zamorano1, Jerusalem Calvo-Gutierrez1, Rafaela Ortega1, M. Carmen Castro Villegas1, Eduardo Collantes-Estévez1, Alejandro Escudero-Contreras1 and Chary Lopez-Pedrera1, 1IMIBIC-Reina Sofia University Hospital, Rheumatology Unit, Cordoba, Spain, 2Rheumatology Unit, IMIBIC-Reina Sofia University Hospital, Cordoba, Spain, 3IMIBIC-Reina Sofia University Hospital, Radiology Unit, Cordoba, Spain

    Background/Purpose: Monocytes play a key role in the pathogenesis of the cardiovascular disease (CVD). Three monocyte subsets have been described based on their CD14 and…
  • Abstract Number: 2270 • 2015 ACR/ARHP Annual Meeting

    Cardiovascular Disease: The Hidden Risk in Persons with Rheumatoid Arthritis

    Karen Soikkeli1 and Glenn Ehresmann2, 1Graduate Nursing (Family Nurse Practitioner Program), Azusa Pacific University, Diamond Bar, CA, 2Rheumatology, Keck School of Medicine, University of Southern California-Los Angeles County Medical Center, Los Angeles, CA

    Background/Purpose: Despite the fact that patients with rheumatoid arthritis (RA) experience a 50-60% increased risk of developing cardiovascular disease (CVD), substantial gaps remain in the…
  • Abstract Number: 3168 • 2015 ACR/ARHP Annual Meeting

    How Strong Cardiovascular Risk Factor Are Gouty Tophi?

    Rada Gancheva1, Atanas Kundurdjiev2, Mariana Ivanova1, Todor Kundurzhiev3 and Zlatimir Kolarov4, 1University Hospital "St. Iv. Rilski", Clinic of Rheumatology, Sofia, Bulgaria, 2University Hospital "Alexandrovska", Clinic of Nephrology, Sofia, Bulgaria, 3Medical University, Faculty of Public Health, Sofia, Bulgaria, 4Clinic of Rheumatology, University Hospital "St. Iv. Rilski", Clinic of Rheumatology, Sofia, Bulgaria

    Background/Purpose: We have not found a study determining cardiovascular (CV) risk in the different stages of gout. This led us to use a complex multimodal…
  • Abstract Number: 36 • 2015 ACR/ARHP Annual Meeting

    The Incidence of Cardiovascular Events in Patients with Rheumatoid Arthritis: a 15 Years Observational Cohort Study

    Koen Laan1, Rabia Agca1,2, Alexandre E. Voskuyl3, Maarten Boers2, Willem Lems2 and Mike T. Nurmohamed1,2, 1Rheumatology, Amsterdam Rheumatology and immunology Center, Reade, Amsterdam, Netherlands, 2Rheumatology, Amsterdam Rheumatology and immunology Center, VU University medical center, Amsterdam, Netherlands, 3Rheumatology, Amsterdam Rheumatology and immunology Center, location VU University medical center, Amsterdam, Netherlands

    Background/Purpose: The increased risk for cardiovascular (CV) disease in rheumatoid arthritis (RA) is well established. However, there are relatively few contemporary cohort studies with long…
  • Abstract Number: 825 • 2015 ACR/ARHP Annual Meeting

    Subclinical Atherosclerosis and Estimation of Cardiovascular Risk in Systemic Sclerosis

    Gulsen Ozen1, Fatmanur Korkmaz2, Murat Sunbul3, Rabia Deniz4, Kursat Tigen3, Pamir Atagunduz1, Nevsun Inanc1 and Haner Direskeneli1, 1Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, 2Department of Internal Medicine, Marmara University Faculty of Medicine, Istanbul, Turkey, 3Department of Cardiology, Marmara University Faculty of Medicine, Istanbul, Turkey, 4Marmara University Faculty of Medicine, Istanbul, Turkey

    Background/Purpose: During the last decade, it has been shown that cardiovascular disease (CVD) in systemic sclerosis (SSc) is increased and accounts for ~30% of the…
  • Abstract Number: 1532 • 2015 ACR/ARHP Annual Meeting

    Occurrence of Valvular Heart Disease in Rheumatoid Arthritis: A Population Based Study

    Tamanna Khullar1, John P. Bois1, Cynthia S. Crowson2, Megan L. Krause3 and Rekha Mankad1, 1Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 2Health Sciences Research, Mayo Clinic, Rochester, MN, 3Rheumatology, Mayo Clinic, Rochester, MN

    Background/Purpose: Patients with rheumatoid arthritis (RA) are known to have an increased risk of cardiovascular disease, particularly atherosclerosis and heart failure.  However, little is known…
  • Abstract Number: 1687 • 2015 ACR/ARHP Annual Meeting

    Increased Carotid Intima-Media Thickness in Psoriatic Arthritis Patients Compared with Systemic Lupus Erythematosus Patients and Healthy Controls

    Handan Yarkan1, Aslıgul Dunya2, Pinar Cetin1, Gercek Can1, Nurullah Akkoc3 and Fatos Onen1, 1Rheumatology, Dokuz Eylul University Faculty of Medicine, Izmir, Turkey, 2Dokuz Eylul University Faculty of Medicine, Izmir, Turkey, 3Department of Rheumatology, Dokuz Eylul University, Faculty of Medicine, Izmir, Turkey

    Background/Purpose: The aim of this study was to investigate carotid intima-media thickness (IMT) in patients with psoriatic arthritis (PsA) and compare it with those in…
  • Abstract Number: 2356 • 2015 ACR/ARHP Annual Meeting

    Major Cardiovascular Events in Gout Patients with Cardiovascular Disease or Heart Failure and Chronic Kidney Disease Initiating on Allopurinol or Febuxostat (Uloric)

    JoAnne Foody1, Robin Turpin2, Beni Tidwell3 and Kathy Schulman4, 1Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 2Medical Affairs, Takeda Pharmaceuticals International, Deerfield, IL, 3ORS, Shrewsbury, MA, 4Outcomes Research Solutions, Inc., Waltham, MA

    Background/Purpose: Xanthine oxidase inhibitors (XOI) reduce both urate levels and oxidative stress in the vasculature, both of which are cardiovascular disease (CVD) risk factors. However,…
  • Abstract Number: 3237 • 2015 ACR/ARHP Annual Meeting

    Decreased Cardiovascular Mortality in Patients with Incident Rheumatoid Arthritis (RA) in Recent Years: Dawn of a New Era in Cardiovascular Disease in RA?

    Elena Myasoedova1, Cynthia S. Crowson2, Eric L. Matteson3, John M. Davis III4, Terry M. Therneau5 and Sherine E. Gabriel6, 1Internal Medicine and Rheumatology, Mayo Clinic, Rochester, MN, 2Health Sciences Research, Mayo Clinic, Rochester, MN, 3Rheumatology, Mayo Clinic, Rochester, MN, 4Division of Rheumatology, Mayo Clinic, Rochester, MN, 5Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 6Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ

    Background/Purpose: Rheumatoid arthritis (RA) is associated with increased cardiovascular (CV) morbidity and mortality as compared to the general population. Recent prospective studies with limited follow-up…
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