ACR Meeting Abstracts

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Abstracts tagged "Cardiovascular disease"

  • Abstract Number: 1447 • 2016 ACR/ARHP Annual Meeting

    Therapeutic Blockade of Interleukin-6 Trans-Signalling Restores Vascular Function in Murine Collagen Induced Arthritis

    Ruth Davies1, Jessica O Williams2, Katie Sime2, Ellyn Hughes2, Lauren A. Jordan2, Charlotte Rawlings2, Derek Lang3, Stefan Rose-John4, Simon A. Jones5, Anwen S. Williams2 and Ernest H. Choy6,7, 1CREATE Centre, Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom, 2Institute of Infection and Immunity, Cardiff University, Cardiff, United Kingdom, 3Institute of Molecular and Experimental Medicine, Cardiff University School of Medicine, Cardiff, United Kingdom, 4Institute of Biochemistry, Christian Albrechts University, Kiel, Germany, 5Infection, Immunity and Biochemistry, School of Medicine, Cardiff University, Cardiff, Wales, 6Section of Rheumatology, Cardiff University, Cardiff, Great Britain, 7CREATE Center, Division of Infection and Immunity,, Cardiff University, Cardiff, United Kingdom

    Background/Purpose: Mortality is increased in rheumatoid arthritis (RA), mainly due to cardiovascular disease (CVD). While molecular mechanisms underlining this clinical observation are unknown, systemic elevations…
  • Abstract Number: 1490 • 2016 ACR/ARHP Annual Meeting

    Metabolic and Cardio-Vascular Benefits of Hydroxychloroquine in Patients with Rheumatoid Arthritis: A Systematic Review and Meta-Analysis

    Claire Rempenault1, Thomas Barnetche2, Jacques Morel3, Cédric Lukas4, Cécile Gaujoux-Viala5, Bernard Combe6 and Charlotte Hua7, 1Rheumatology, CHU Lapeyronie, University of Montpellier, France, 2Rheumatology Department, Pellegrin University Hospital, BORDEAUX, France, 3Rheumatology, Department of Rheumatology, Montpellier University Hospital, Montpellier, France, 4Rheumatology, CHU Lapeyronie and EA2415, Montpellier University, University of Montpellier, France, 5Rheumatology Department, University Hospital of Nîmes and EA2415, Montpellier University, Nîmes, France, 6Département Rhumatologie, Hôpital Lapeyronie, Montpellier, France, 7Department of Rheumatology, Lapeyronie Hospital and Montpellier University, Montpellier, France

    Background/Purpose: Cardiovascular disease (CVD) is the leading cause of mortality in rheumatoid arthritis (RA) patients. Hydroxychloroquine (HCQ) has been shown to improve major outcomes like…
  • Abstract Number: 2170 • 2016 ACR/ARHP Annual Meeting

    Cardiovascular Risk in Patients with Psoriasis, Psoriatic and Rheumatoid Arthritis: A Prospective Study Using Secured Anonymised Information Technology Databank in Wales, United Kingdom

    Ernest H. Choy1, Roxanne Cooksey2, Sinead Brophy2, Jonathan Kennedy2, Fabiola Fernandez-Gutierrez3, Ruth Davies4, Timothy Pickles5 and Vincent Piguet6, 1CREATE Center, Division of Infection and Immunity,, Cardiff University, Cardiff, United Kingdom, 2College of Medicine, Swansea University, Swansea, United Kingdom, 3Cancer Research UK Manchester Institute, Manchester, United Kingdom, 4CREATE Centre, Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom, 5CREATE Center, Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom, 6Division of Infection and Immunity, Cardiff University, Cardiff, United Kingdom

    Background/Purpose: Compared with cardiovascular (CV) risk in rheumatoid arthritis (RA), precise CV risk in psoriatic arthritis (PsA) and psoriasis is less established, particularly the relative…
  • Abstract Number: 3103 • 2016 ACR/ARHP Annual Meeting

    Apolipoprotein L1 Risk Variants Associate with Prevalent Cardiovascular Disease in African American Systemic Lupus Erythematous Patients

    Ashira Blazer1, Robert M Clancy2, H. Michael Belmont3, Peter M. Izmirly3, Androo Markham4 and Jill P. Buyon4, 1Division of Rheumatology, NYU School of Medicine, New York, NY, 2Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, 3New York University School of Medicine, New York, NY, 4Medicine, New York University School of Medicine, New York, NY

    Background/Purpose:  Two Apolipoprotein L1 (APOL1) risk variants (RV), G1 and G2, located on chromosome 22q12.3, have been associated with excess renal risk in African Americans…
  • Abstract Number: 563 • 2016 ACR/ARHP Annual Meeting

    Factors Associated with Cognitive Impairment in Korean Adults with Rheumatoid Arthritis

    So Young Shin1, Joo Hyun Lee2 and Bo Young Yoon3, 1Department of Nursing, Inje University, College of Medicine, Department of Nursing, Busan, Korea, The Republic of, 2Rheumatology/Internal medicine, Inje University Ilsan Paik Hospital, Goyang, Korea, The Republic of, 3Rheumatology/Internal medicine, Inje Iniversity Ilsan Paik Hospital, Goyang, Korea, The Republic of

    Background/Purpose:  For persons with chronic diseases such as rheumatoid arthritis (RA), intact cognitive function is crucial for performing main daily activities and adhering to self-management…
  • Abstract Number: 1464 • 2016 ACR/ARHP Annual Meeting

    Utility of Relative Cardiovascular Risk Score Scales and Vascular Age Predictors in Patients with Reumathoid Arthritis UNDER 50 YEARS of Age

    Andrea Zacarias1, Carmen Gomez Vaquero2, Francisco Javier Narváez3, Joan Miquel Nolla4, Miguel Angel González-Gay5, Carlos González-Juanatey6 and Javier Llorca7, 1Hospital Universitari de Bellvitge, Barcelona, Spain, 2Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 3Rheumatology, Hospital Universitario de Bellvitge-IDIBELL, L’Hospitalet de Llobregat, Barcelona, Spain, 4Rheumatology, Bellvitge University Hospital, Barcelona, Spain, 5Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, University of Cantabria, Santander, Spain, 6Cardiology Division, Hospital Xeral-Calde, Lugo, Spain, 7Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), IDIVAL, Santander, Spain

    Background/Purpose: Rheumatoid Arthritis (RA) is associated with a greater cardiovascular mortality than the general population of the same age and gender. Cardiovascular events prediction scales,…
  • Abstract Number: 1494 • 2016 ACR/ARHP Annual Meeting

    Myocardial Structure, Function, and Fibrosis in Patients with Rheumatoid Arthritis and Matched Control Subjects

    Michelle J. Ormseth1, William Bradham2, Comfort Elumogo3, Srikanth Palanisamy4, Chia Liu5, Mark Lawson2, Jonathan Soslow2, Nadine Kawel6, David A. Bluemke7 and C Michael Stein2, 1Medicine, Vanderbilt University Medical Center, Nashville, TN, 2Vanderbilt University Medical Center, Nashville, TN, 3National Institutes of Health, Bethesada, MD, 4Cornell University, Ithaca, NY, 5National Institutes of Health, Bethsada, MD, 6National Institutes of Health, Bethsada, TN, 7National Institutes of Health, Bethesda, MD

    Background/Purpose: The prevalence of heart failure is increased 2-fold in RA; this is not explained by ischemic heart disease or other risk factors for heart…
  • Abstract Number: 2172 • 2016 ACR/ARHP Annual Meeting

    Impact of Biologic and Non-Biologic Treatment on the Incidence of Traditional Cardiovascular Risk Factors Among Patients with Rheumatoid Arthritis, Psoriatic Arthritis, or Psoriasis

    Helga Radner1, Tamara Lesperance2, Neil A. Accortt3 and Daniel H. Solomon4, 1Rheumatology, Medical University of Vienna, Vienna, Austria, 2DOCS Global, Inc., North Wales, PA, 3Center for Observational Research, Amgen, Inc., Thousand Oaks, CA, 4Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: Studies have suggested that the chronic inflammatory nature of rheumatic conditions (rheumatoid arthritis (RA) and psoriatic arthritis (PsA)) as well as psoriasis (PsO) may…
  • Abstract Number: 3138 • 2016 ACR/ARHP Annual Meeting

    Sustained Improvement in Follow-up of Hypertension in Rheumatology Patients: Results of an Intervention Sustainability Assessment

    Edmond Ramly1,2, Daniel Panyard3, Diane Lauver4, Emmanuel Sampene5, Zhanhai Li5, Heather Johnson6, Patrick McBride6, Kristin Steffen Lewicki7 and Christie M. Bartels8, 1Industrial and Systems Engineering, University of Wisconsin-Madison College of Engineering, Madison, WI, 2Department of Medicine, University of Wisconsin-Madison, Madison, WI, 3Population Health, University of Wisconsin School of Medicine and Public Health, Madison, WI, 4University of Wisconsin-Madison School of Nursing, Madison, WI, 5Biostatistics, University of Wisconsin School of Medicine and Public Health, Madison, WI, 6Cardiology/Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 7Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 8Rheumatology/Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI

    Background/Purpose: Hypertension (HTN) is the most prevalent comorbid cardiovascular disease (CVD) risk factor among adults with rheumatic conditions.  However, we previously found that high blood…
  • Abstract Number: 589 • 2016 ACR/ARHP Annual Meeting

    Netosis-Derived Products Might Have Diagnostic Potential for Disease Activity, Atherosclerosis and Analysis of Therapeutic Effectiveness in Rheumatoid Arthritis Patients

    Chary Lopez-Pedrera1, Patricia Ruiz-Limon2, Carlos Perez-Sanchez1, Yolanda Jiménez-Gómez1, Maria Carmen Abalos-Aguilera2, Ivan Arias de la Rosa1, Pedro Segui1, Pilar Font-Ugalde1, Maria Ángeles Aguirre Zamorano1, Jerusalem Calvo-Gutierrez1, Rafaela Ortega-Castro1, M. Carmen Castro-Villegas3, Rocio Gonzalez-Conejero4, Constantino Martinez4, Eduardo Collantes-Estévez1, Alejandro Escudero-Contreras2 and Nuria Barbarroja1, 1Rheumatology service, IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, 2Rheumatology Service, IMIBIC/Reina Sofia Hospital/University of Cordoba, Cordoba, Spain, 3Rheumatology Service, IMIBIC/Reina Sofia Hospital/University of Cordoba, Córdoba, Spain, 4Regional Centre for Blood Donation, University of Murcia, Murcia, Spain

    Background/Purpose: Neutrophil extracellular traps (NETs) have recently been implicated in vascular damage and atherothrombosis. Extruded DNA fibers containing multiple proinflammatory and thrombotic molecules induce the…
  • Abstract Number: 1467 • 2016 ACR/ARHP Annual Meeting

    Cardiovascular Risk Assessment in Persons with Rheumatoid Arthritis: Non-Invasive Arterial Health Testing to Assess Subclinical Risk of Cardiovascular Disease

    Erin Scanlon1, Rekha Mankad2, Cynthia S. Crowson3, Iftikhar Kullo4, Sharon Mulvagh2, Eric L. Matteson1, Zoran Kvrgic1 and John M. Davis III5, 1Rheumatology, Mayo Clinic, Rochester, MN, 2Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 3Health Sciences Research, Mayo Clinic, Rochester, MN, 4Department of Internal Medicine, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 5Division of Rheumatology, Mayo Clinic, Rochester, MN

    Background/Purpose:   Measures of arterial health may be useful in assessing the risk of atherosclerotic cardiovascular disease (ASCVD) in patients with rheumatoid arthritis (RA). The…
  • Abstract Number: 1495 • 2016 ACR/ARHP Annual Meeting

    Lipoprotein(a) Concentrations in Rheumatoid Arthritis on Biologic Therapy: Results from the Cardiovascular in Rheumatology [CARMA] Study Project

    Maria Carmen Garcia-Gomez1, Maria Auxiliadora Martin2, Santos Castañeda3, Fernando Sánchez-Alonso4, Miren Uriarte Ecenarro5, Carlos González-Juanatey6, Romera-Baures Monserrat7, Santos-Rey Jose8, Jose A Pinto-Tasende9, Estefania QuesadaMasachs10, Jesús Tornero11, Olga Martínez González12, Tatiana Cobo-Ibáñez13, Eugenio Chamizo Carmona14, Sara Manrique-Arija15, Dolores Fábregas-Canales16, Federico Díaz-González17, Javier Llorca18, Miguel Angel González-Gay19 and CARMA Collaborative Group, 1Rheumatology, Consorci Sanitari de Terrassa, Terrassa (Barcelona), Spain, 2Research Unit of Spanish Society of Rheumatology,, Madrid, Spain, 3Rheumatology, Hospital de la Princesa, IIS-IP, Madrid, Spain, 4Research Unit of Spanish Society of Rheumatology, Madrid, Spain, 5Donostia University Hospital, San Sebastian, Spain, 6Division or Cardiology, Hospital Lusus Augusti, Lugo, Spain, 7Rheumatology, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat (Barcelona), Spain, 8Rheumatology, Hospital Virgen de la Salud, Toledo, Spain, 9Rheumatology Division, INIBIC-Complejo Hospitalario Universitario A Coruña (CHUAC), A Coruna, Spain, 10Rheumatology, Hospital Universitari Vall d’Hebron, Barcelona, Spain, 11Rheumatology Department, Hospital Universitario Guadalajara, Guadalajara, Spain, 12Rheumatology, HOSPITAL CLÍNICO UNIVERSITARIO DE SALAMANCA, Salamanca, Spain, 13Hospital Universitario Reina Sofía, Universidad Europea de Madrid, Madrid, Spain, 14Rheumatology, Hospital de Mérida, Mérida, Spain, 15Rheumatology, Hospital Carlos Haya, Malaga, Spain, 16Rheumatology, Hospital de Barbastro, Barbastro (Huesca), Spain, 17Rheumatology, Hospital Universitario de Canarias, S/C Tenerife, Spain, 18Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), IDIVAL, Santander, Spain, 19Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, University of Cantabria, Santander, Spain

    Background/Purpose: Plasma concentrations of lipoprotein (a) [Lp(a)], a lipoprotein with proatherogenic and thrombogenic properties, have a strong genetic basis, although high concentrations of Lp(a) have…
  • Abstract Number: 2174 • 2016 ACR/ARHP Annual Meeting

    Effect of Anti-Rheumatic Treatment on Selenium Levels in Rheumatoid Arthritis, Psoriatic Arthritis and Ankylosing Spondylitis

    Gia Deyab1, Ingrid Hokstad2, Milada Cvancarova Småstuen3, Stefan Agewall4, Jon Elling Whist5 and Ivana Hollan5,6,7,8, 1Department of Medical Biochemistry, Innlandet Hospital Trust, Lillehammer, Norway, 2Lillehammer Hospitat for Rheumatic Diseases, Lillehammer, Norway, 3Institution of health care - Health science PhD program, Oslo and Akershus University College, Oslo, Norway, 4University of Oslo, Oslo, Norway, 5Innlandet Hospital Trust, Lillehammer, Norway, 6Brigham and Women’s Hospital, Boston, MA, 7Harvard Medical School, Boston, MA, 8Lillehammer Hospital for Rheumatic Diseases, Lillahammer, Norway

    Background/Purpose: The cause of the increased cardiovascular risk in inflammatory rheumatic diseases (IRDs) is still unclear. Intriguingly, selenium-deficiency, which might be caused by poor diet or…
  • Abstract Number: 22 • 2016 ACR/ARHP Annual Meeting

    Incidence and Factors Associated with the Development of Non Alcoholic Fatty Liver Disease(NAFLD) Among Patients with Rheumatoid Arthritis

    Ani John1, Angela Witt Prehn2, Hebatullah Tawfik2, George W. Reed3 and Joel Kremer4, 1School of Health Sciences, Walden University, Minneapolis, CA, 2School of Health Sciences, Walden University, Minneapolis, MN, 3Corrona, LLC, Southborough, MA, 4The Center for Rheumatology, Albany Medical College, Albany, NY

    Background/Purpose: NAFLD is a leading cause of chronic liver disorders, unrelated to significant alcohol use. RA and NAFLD have shared risk factors such as age,…
  • Abstract Number: 743 • 2016 ACR/ARHP Annual Meeting

    Long-Term Hydroxychloroquine Therapy and Low-Dose Aspirin May Have an Additive Effectiveness in the Primary Prevention of Cardiovascular Events in Patients with Systemic Lupus Erythematosus

    Serena Fasano1, Michele Iudici2, Ilenia Pantano3, Luciana Pierro3 and Gabriele Valentini4, 1Internal and Experimental Medicine Naples, Italy, Rheumatology Unit, Second University of Naples, Naples, Italy, 2National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, 3Rheumatology Unit, Second University of Naples, Naples, Italy, 4Internal and Experimental Medicine, Rheumatology Unit, Second University of Naples, Naples, Italy

    Background/Purpose: Hydroxychloroquine (HCQ) is a mainstay of treatment in patients with SLE. It has been demonstrated to reduce disease activity and prevent damage accrual and…
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