Abstracts tagged "Cardiovascular disease"

Abstract Number: 973 • 2016 ACR/ARHP Annual Meeting
Clinical Characterization of Patients with World Health Organization Group 2 Pulmonary Hypertension in the Pulmonary Hypertension Assessment and Recognition of Outcomes in Scleroderma Cohort
Jessica K. Gordon¹, Jackie Szymonifka², Matthew R. Lammi³, Virginia D. Steen⁴ and PHAROS Investigators, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Epidemiology and Biostatistics, Hospital for Special Surgery, New York, NY, ³Louisiana State University Health Sciences Center, Pulmonary and Critical Medicine, New Orleans, LA, ⁴Rheumatology, Georgetown University Medical Center, Washington, DC
Background/Purpose: Pulmonary hypertension (PH) is a leading cause of death in patients (pts) with Systemic Sclerosis (SSc). The World Health Organization (WHO) classifies PH into…
Abstract Number: 1484 • 2016 ACR/ARHP Annual Meeting
Exploring the Link Between RA Disease Activity, Lipid Levels, and Cardiovascular Disease in an Early Inflammatory Arthritis Cohort
Saurash Reddy, Xiaobo Meng and Carol Hitchon, University of Manitoba, Winnipeg, MB, Canada
Background/Purpose: Rheumatoid arthritis (RA) has been established as a risk factor for cardiovascular disease (CVD), with systemic inflammation being linked with atherosclerosis. Traditional CVD risk…
Abstract Number: 2055 • 2016 ACR/ARHP Annual Meeting
Myocardial Abnormalities Are Associated with Corrected QT Interval in Patients with Rheumatoid Arthritis without Cardiac Symptoms Assessed Using Cardiac Magnetic Resonance Imaging
Yasuyuki Kobayashi¹, Hitomi Kobayashi², Atsuma Nishiwaki³, Kaita Sugiyama³, Yosuke Nagasawa⁴, Takamasa Nozaki², Noboru Kitamura⁵, Masami Takei⁴, Natsumi Ikumi⁶ and Hirotake Inomata³, ¹Advanced Biomedical Imaging Informatics, St.Marianna University School of Medicine, Kawasaki, Japan, ²Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ³Nihon University School of Medicine, Tokyo, Japan, ⁴Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ⁵Hematology and Rheumatology, NIhon University School of Medicine, Tokyo, Japan, ⁶Nihon University School of Medicine, Shinjuku, Japan
Background/Purpose: Individuals with rheumatoid arthritis (RA) have two-fold higher risk of sudden death than age- and sex-matched controls without RA. We hypothesized that myocardial abnormalities…
Abstract Number: 2866 • 2016 ACR/ARHP Annual Meeting
Lupus HDL Induces Pro-Inflammatory Responses in Macrophages By Binding LOX1Rand Failing to Promote ATF3 Activity
Carolyne K. Smith¹, Nickie Seto¹, Anuradha Vivekanandan-Giri², Wenmin Yuan³, Martin Playford⁴, Zerai G. Manna⁵, Sarfaraz A. Hasni⁶, Rui Kuai³, Nehal N. Mehta⁴, Anna Schwendeman³, Subramaniam Pennathur² and Mariana Kaplan⁷, ¹Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ²Internal Medicine/Nephrology, University of Michigan Nephrology, Ann Arbor, MI, ³Department of Medicinal Chemistry and the Biointerfaces Institute, University of Michigan, Ann Arbor, MI, ⁴NHLBI, National Institutes of Health, Bethesda, MD, ⁵National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁶Lupus Clinical Research Program, Office of the Clinical Director, NIAMS/NIH, Bethesda, MD, ⁷NIAMS/NIH, Bethesda, MD
Background/Purpose: Recent evidence indicates that high-density lipoprotein (HDL) exerts vasculoprotective activities by promoting activating transcription factor 3 (ATF3), leading to down-regulation of TLR-induced inflammatory responses.…
Abstract Number: 421 • 2016 ACR/ARHP Annual Meeting
Educating Patients on the Cardiovascular Risks of Rheumatoid Arthritis: Usual Care Versus a Structured Approach
Marcia Genta¹ and Robert M. Genta², ¹Dallas Arthritis Center, Dallas, TX, ²Laboratory, Dallas Arthritis Center, Dallas, TX
Background/Purpose: Rheumatoid Arthritis (RA) carries a considerable increase of the risks for cardiovascular (CV) disease. It is unclear how well patients with RA understand such…
Abstract Number: 983 • 2016 ACR/ARHP Annual Meeting
Objectively Assessed Sedentary Behaviour and Light Physical Activity Are Associated with Long-Term Cardiovascular Risk in People Living with Rheumatoid Arthritis Independently of Moderate-to-Vigorous Physical Activity
Sally Fenton^1,2, Jet Veldhuijzen van Zanten^2,3, George D. Kitas^2,4, Joan Duda⁴, Peter Rouse⁵, Chen-an Yu¹ and George Metsios^2,6, ¹School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom, ²Department of Rheumatology, Russells Hall Hospital, Dudley Group of Hospitals NHS Foundation Trust, Dudley, United Kingdom, ³University of Birmingham, Birmingham, United Kingdom, ⁴School of Sport, Exercise and Rehabilitation, University of Birmingham, Birmingham, United Kingdom, ⁵Department for Health, University of Bath, Bath, United Kingdom, ⁶Department of Physical Activity Exercise and Health, University of Wolverhampton, Walsall, United Kingdom
Background/Purpose: Rheumatoid Arthritis (RA) can result in functional disability and is associated with an increased risk of cardiovascular disease (CVD). In healthy adults and…
Abstract Number: 1487 • 2016 ACR/ARHP Annual Meeting
Comparison Between Intima-Media Thickness and Coronary Artery Tomography in Subclinical Atheroesclerosis Detection in Rheumatoid Arthritis
Carlos Fernández-Díaz¹, Lucia Cristina Domínguez-Casas¹, Leyre Riancho-Zarrabeitia¹, Alfonso Corrales¹, José Antonio Parra², Virginia Portilla³, Montserrat Santos-Gómez⁴, Patrick H Dessein⁵, Ricardo Blanco¹ and Miguel Angel Gonzalez-Gay¹, ¹Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ²Radiology Division, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ³Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ⁴Rheumatology, Hospital Can Misses, Ibiza, Spain, ⁵Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Background/Purpose: Intima media thickness (IMT) and coronary artery calcification (CAC) quantification using multidetector computed tomography (MDCT) scanner are useful in detecting subclinical atherosclerosis and…
Abstract Number: 2160 • 2016 ACR/ARHP Annual Meeting
Allopurinol Use and the Risk of Acute Cardiovascular Events in Patients with Gout and Diabetes
Jasvinder A. Singh¹, Rekha Ramachandaran² and Jeffrey Curtis³, ¹Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, Birmingham, AL, ³Division Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: To examine the effect of allopurinol on the risk of incident myocardial infarction (MI) or stroke in patients with gout and diabetes Methods: We…
Abstract Number: 3072 • 2016 ACR/ARHP Annual Meeting
Increased Platelet Reactivity in Gout: Relationship to Tophus Burden and Colchicine Use
Richard Conway¹, Claire-Louise Murphy², Anne Madigan³, Patricia Kavanagh⁴, Liz Geraghty³, Niamh Redmond⁵, Laura Helbert⁶, John J. Carey⁷, Eimear Dunne⁸, Dermot Kenny⁸ and Geraldine M. McCarthy⁹, ¹CARD Newman Research Fellow, University College Dublin, Dublin, Ireland, ²Rayne Institute, Centre for Rheumatology Research, UCL Division of Medicine, London, United Kingdom, ³Rheumatology, Mater Misericordiae University Hospital, Dublin 7, Ireland, ⁴Rheumatology Department, Mater Public Hospital, Dublin 7, Ireland, ⁵UCD Clinical Research Centre, Dublin, Ireland, ⁶Rheumatology, Mater Misericordiae University Hospital, Dublin, Ireland, ⁷Rheumatology, Galway University Hospitals, Galway, Ireland, ⁸Molecular and Cellular Therapeutics, RCSI, Dublin 2, Ireland, ⁹Div of Rheumatology, Mater Misericordiae University Hospital, Dublin, Ireland
Background/Purpose: Patients with gout have an increased risk of cardiovascular events. The presence of tophi is associated with enhanced cardiovascular risk. Increased platelet reactivity is…
Abstract Number: 523 • 2016 ACR/ARHP Annual Meeting
Mortality Profile of Patients with Rheumatoid Arthritis in France and Its Change in 10 Years
Jerome Avouac¹, Fazia Amrouche², Christophe Meune³, Grégoire Rey⁴, Andre Kahan⁵ and Yannick Allanore⁶, ¹Rheumatology A department and INSERM U1016, Paris Descartes University, Cochin Hospital, Paris, France, ²Paris Descartes University, Cochin Hospital, Paris, France, ³Cardiology department, Université Paris XIII, Hôpitaux Universitaires Paris-Seine-Saint-Denis, Bobigny, France, ⁴Inserm-CépiDc, Hospital Bicêtre, Le Kremlin-Bicêtre, France, ⁵Service de Rhumatologie A, Hopital Cochin, Paris Cedex 14, France, ⁶Rheumatology, Paris Descartes University, Paris, France
Background/Purpose: Rheumatoid arthritis (RA) is associated with an excess of mortality. This risk depends on the disease activity, severity and associated comorbidities. Our objective was…
Abstract Number: 1230 • 2016 ACR/ARHP Annual Meeting
Allopurinol Use and the Risk of Stroke in the Elderly
Jasvinder A. Singh¹ and Shaohua Yu², ¹Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: To assess the effect of allopurinol use on the risk of stroke in the elderly Methods: We used the 5% random sample of Medicare…
Abstract Number: 1488 • 2016 ACR/ARHP Annual Meeting
Comparison Between Carotid Ultrasonography and Coronary Artery Calcification Score to Detect Subclinical Atherosclerosis in Rheumatoid Arthritis
Lucia Cristina Domínguez-Casas¹, Leyre Riancho-Zarrabeitia¹, Carlos Fernández-Díaz¹, Nuria Vegas-Revenga², Alfonso Corrales¹, José Antonio Parra³, Montserrat Santos-Gómez⁴, Virginia Portilla², Patrick H Dessein⁵, Ricardo Blanco¹ and Miguel Angel Gonzalez-Gay¹, ¹Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ²Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ³Radiology Division, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ⁴Rheumatology, Hospital Can Misses, Ibiza, Spain, ⁵Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Background/Purpose: Carotid ultrasonography (CU) and coronary artery calcification score (CAC) evaluated by multidetector computed tomography (MDCT) scanner are useful in detecting subclinical atherosclerosis in…
Abstract Number: 2169 • 2016 ACR/ARHP Annual Meeting
Presence of Cardiovascular Risk Factors Across Different Inflammatory Joint Disease Entities: Results from a Norwegian, Multi-Centre Project
Grunde Wibetoe¹, Eirik Ikdahl², Silvia Rollefstad², Anne Salberg³, Dag Magnar Soldal⁴, Tore K Kvien⁵, Glenn Haugeberg⁶ and Anne Grete Semb⁷, ¹Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Diakonhjemmet Hospital, Oslo, Norway, ³Hospital for Rheumatic Diseases, Lillehammer, Norway, ⁴Rheumatology, Hospital of Southern Norway, Kristiansand, Norway, ⁵Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁶Martina Hansens Hospital, Bærum, Norway, ⁷Preventive Cardio-Rheuma clinic, Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: EULAR recommendations for cardiovascular disease (CVD) risk management in inflammatory joint diseases (IJD) advocates annual CVD risk assessments to reduce the increased CVD risk.…
Abstract Number: 3101 • 2016 ACR/ARHP Annual Meeting
Lipoprotein Profile and Serum Glycoprotein Acetylation As Markers of Cardiovascular Risk in Systemic Lupus Erythematosus
Simantini Sakhardande¹, Monica Purmalek¹, Yenealem Temesgen-Oyelakin², Maureen Sampson³, Aditya Joshi⁴, Alice Fike⁵, Michael Davis⁶, Taufiq Salahuddin⁷, Balaji Natarajan⁷, Joseph Lerman⁷, Zerai G. Manna⁸, Amit Dey⁹, Marcus Chen⁷, Sarfaraz Hasni⁸, Nehal N. Mehta⁷, Alan Remaley⁷ and Mariana Kaplan¹⁰, ¹Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ²National Institute of Arthritis and Musculoskeletal and Skin Diseases,, National Institutes of Health, Bethesda, MD, ³Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD, ⁴National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, ⁵National Institutes of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁶NIH, Bethesda, MD, ⁷NHLBI, National Institutes of Health, Bethesda, MD, ⁸National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁹National Institutes of Health, Bethesda, MD, ¹⁰NIAMS/NIH, Bethesda, MD
Background/Purpose: The risk of atherosclerotic cardiovascular disease (CVD) is significantly increased in systemic SLE compared to age and gender matched controls. The implementation of nuclear…
Abstract Number: 524 • 2016 ACR/ARHP Annual Meeting
A Self-Determination Theory Based Intervention to Increase Levels of Cardiorespiratory Fitness, Self-Determined Motivation, Physical Activity and Improve Health Outcomes Among Patients Living with Rheumatoid Arthritis
Joan Duda¹, Sally Fenton^1,2, Jet Veldhuijzen van Zanten^2,3, George Metsios^2,4, Peter Rouse⁵, Nikos Ntoumanis⁶, Chen-an Yu⁷, Yiannis Koutedakis⁸ and George D. Kitas^1,2, ¹School of Sport, Exercise and Rehabilitation, University of Birmingham, Birmingham, United Kingdom, ²Department of Rheumatology, Russells Hall Hospital, Dudley Group of Hospitals NHS Foundation Trust, Dudley, United Kingdom, ³University of Birmingham, Birmingham, United Kingdom, ⁴Department of Physical Activity Exercise and Health, University of Wolverhampton, Walsall, United Kingdom, ⁵Department for Health, University of Bath, Bath, United Kingdom, ⁶School of Psychology & Speech Pathology, Curtin University, Perth, Australia, ⁷School of Sport, Exercise and Rehabilitation Sciences, University of Birmingham, Birmingham, United Kingdom, ⁸University of Wolverhampton, Wolverhampton, United Kingdom
Background/Purpose: Rheumatoid arthritis (RA) may cause joint damage leading to physical dysfunction and associates with increased cardiovascular (CV) risk. Regular physical activity (PA) can attenuate…

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