Abstracts tagged "Cardiovascular disease and rheumatoid arthritis (RA)"

Abstract Number: 2131 • 2015 ACR/ARHP Annual Meeting
Younger Age and Female Gender Are the Main Determinants of Underestimation of Cardiovascular Risk in Rheumatoid Arthritis Patients
Calin Popa^1,2, Alexander Rennings³, Alfons A. den Broeder⁴, Frank H.J. van den Hoogen⁴, Inger L. Meek¹ and Jaap Fransen¹, ¹Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Rheumatology, Bernhoven Hospital, Uden, Netherlands, ³Internal Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ⁴Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands
Background/Purpose: Rheumatoid arthritis (RA) patients have an increased cardiovascular (CV) risk. Current algorithms generally underestimate the risk in these patients [1]. In a meta-analysis, we…
Abstract Number: 2617 • 2014 ACR/ARHP Annual Meeting
No Evidence of Accelerated Atheromatosis, Increased Arterial Stiffness or Hypertrophy in Ankylosing Spondylitis: A Systematic Case-Control Study
Aikaterini I. Arida¹, Maria Konsta¹, Alexios Iliopoulos², Maria Tektonidou³, George Konstantonis¹, George D. Kitas⁴, Athanasios D. Protogerou¹ and Petros P. Sfikakis¹, ¹First Department of Propedeutic Internal Medicine, Laikon Hospital, Athens University Medical School, Athens, Greece, ²Department of Rheumatology, Veterans Administration Hospital, Athens, Greece, ³First Department of Internal Medicine, Laikon Hospital, Athens University Medical School, Athens, Greece, ⁴The Dudley Group of Hospitals NHS Foundation Trust, Dudley, and Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, United Kingdom
Background/Purpose: Chronic inflammatory arthritis is associated with increased cardiovascular disease (CVD) risk. The mechanisms behind this link include chronic inflammation, comorbidities and disease-related drugs. CV…
Abstract Number: 2021 • 2014 ACR/ARHP Annual Meeting
The Association Between Rheumatoid Factor and Cardiovascular Disease in Healthy Adults
Chisun Min¹, Mitsumasa Kishimoto¹, Gautam A. Deshpande², Shunya Kaneshita¹, Masei Suda¹, Yuri Ohara¹, Yoichiro Haji¹, Ryo Rokutanda¹, Yasuhiro Suyama¹, Hisanori Shimizu¹, Tokutaro Tsuda¹, Ken-ichi Yamaguchi¹, Akira Takeda³, Yukio Matsui¹ and Masato Okada¹, ¹Immuno-Rheumatology Center, St. Luke's International Hospital, Tokyo, Japan, ²Center for Clinical Epidemiology, St. Luke's Life Science Instutute, Tokyo, Japan, ³Division of Clinical Immunology & Rheumatology, International University of Health and Welfare Hospital, Nasu-shiobara, Japan
Background/Purpose Rheumatoid arthritis (RA) has been shown to be a risk factor for cardiovascular disease (CVD). Both elevated rheumatoid factor (RF) and anti-citrullinated protein antibodies…
Abstract Number: 1464 • 2014 ACR/ARHP Annual Meeting
Numbers of Circulating CD4 Positive CD28null T Cells Are Increased in Patients with Rheumatoid Arthritis and Are Associated with Rheumatoid Factor Positivity but Not Subclinical Cardiovascular Disease
Sarah Skeoch¹, John Waterton², Yvonne Alexander³ and Ian N. Bruce⁴, ¹Arthritis Research UK Centre for Epidemiology and NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom, ²Bioimaging Institute, University of Manchester, Manchester, United Kingdom, ³Healthcare Science Research Institute, Manchester Metropolitan University, Manchester, United Kingdom, ⁴Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom
Background/Purpose CD4+ T cells which lack CD28 co-expression (CD28null cells) account for less than 2.5% of CD4+ T cells in healthy individuals. These cells are…
Abstract Number: 1443 • 2014 ACR/ARHP Annual Meeting
Increased Occurence of Carotid and Femoral Plaques, but Not Increased Arterial Stiffness of Hypertrophy, in Classical Risk Factor-Free Patients with Rheumatoid Arthritis
Aikaterini I. Arida¹, Evaggelia Zampeli¹, George Konstantonis¹, Kalliopi Fragkiadaki¹, George D. Kitas², Athanasios D. Protogerou¹ and Petros P. Sfikakis¹, ¹First Department of Propedeutic Internal Medicine, Laikon Hospital, Athens University Medical School, Athens, Greece, ²The Dudley Group of Hospitals NHS Foundation Trust, Dudley, and Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, United Kingdom
Background/Purpose Several lines of evidence indicate that classical cardiovascular disease (CVD) risk factors, such as arterial hypertension, diabetes mellitus, smoking and dyslipidemia, are significantly increased…
Abstract Number: 1417 • 2014 ACR/ARHP Annual Meeting
Red Cell Distribution Width: A Measure for Cardiovascular Risk in Rheumatoid Arthritis Patients?
Sobia Hassan¹, Maria Antonelli² and Stanley P Ballou³, ¹Rheumatology, Case Western Reserve University, MetroHealth Medical Center, Cleveland, OH, ²Rheumatology, Case Western Reserve University School of Medicine at MetroHealth Medical Center, Cleveland, OH, ³Division of Rheumatology, MetroHealth Medical Center / Case Western Reserve University, Cleveland, OH
Background/Purpose: Red cell distribution width (RDW) is a measure of the variation in red blood cell size reported on the automated complete blood count. Although…
Abstract Number: 1394 • 2014 ACR/ARHP Annual Meeting
Low Vitamin D Level Is Not Associated with Increased Risk of Cardiovascular Disease in Rheumatoid Arthritis Patients
Tarun S. Sharma¹, Xiaoqin Tang², Deepak Vedamurthy³, Jonida Cote⁴ and Androniki Bili⁴, ¹Rheumatology, Geisinger Medical Center, Danville, PA, ²Biostatistics, Geisinger Center for Health Research, Danville, PA, ³Hospital Medicine, Geisinger Medical Center, Danville, PA, ⁴Rheumatology, Geisinger Health System, Danville, PA
Background/Purpose: Cardiovascular disease (CVD) is the leading cause of death in patients with Rheumatoid Arthritis (RA). Vitamin D deficiency is prevalent in RA and it…
Abstract Number: 1372 • 2014 ACR/ARHP Annual Meeting
Prevalence of Cardiovascular Disease in US Veterans with Rheumatoid Arthritis and Hepatitis C Infection
Ruchika Patel¹, Ted R. Mikuls², J. Steuart Richards³, Grant W. Cannon⁴, Gail S. Kerr⁵, Lisa A. Davis⁶, Liron Caplan⁷ and Joshua F. Baker⁸, ¹Medicine/Rheumatology, University of Pennsylvania and Philadelphia VA Medical Center, Philadelphia, PA, ²Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, ³Rheumatology, Washington DC VA and Georgetown University, Washington, DC, ⁴Division of Rheumatology, Salt Lake City VA and University of Utah, Salt Lake City, UT, ⁵Rheumatology, Washington DC VAMC, Georgetown and Howard University, Washington, DC, ⁶Denver VAMC and Univ of Colorado School of Medicine, Aurora, CO, ⁷Div of Rheumatology, Denver VA and Univ of Colorado School of Medicine, Aurora, CO, ⁸Medicine/Rheumatology, University of Pennsylvania and Philadelphia VAMC, Philadelphia, PA
Background/Purpose: Chronic hepatitis C (HCV) and rheumatoid arthritis (RA) have both been associated with higher cardiovascular disease (CVD) in US veterans. Whether the presence of…
Abstract Number: 1364 • 2014 ACR/ARHP Annual Meeting
Accelerated Diastolic Dysfunction in Premenopausal Women with Rheumatoid Arthritis
Yune-Jung Park¹, JiHee Kim², Ki-Jo Kim³, Wan-Uk Kim⁴, Chul-Soo Cho⁵, Kyung-Su Park⁶ and Ki-Dong Yoo², ¹Internal Medicine, St. Vincent's Hospital, The Catholic University of Korea, Suwon, South Korea, ²Division of Cardiology, Department of Internal Medicine, St.Vincent’s Hospital, The Catholic University of Korea, Suwon, Republic of Korea, Suwon, South Korea, ³Internal Medicine, St. Vincent’s Hospital, The Catholic University of Korea, Suwon, South Korea, ⁴Internal Medicine, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, South Korea, ⁵Internal Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, South Korea, ⁶Division of Rheumatology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul, South Korea
Background/Purpose: Disturbances of diastolic function precede systolic heart failure and, although clinically silent, represent the earliest sign of cardiac involvement. Diastolic dysfunction is associated with…
Abstract Number: 1374 • 2014 ACR/ARHP Annual Meeting
A Comparison of the Risk for Cardiovascular Event in Patients with Rheumatoid Arthritis Treated with Biologic Disease Modifiers and Patients Treated with Methotrexate Only
Majed Khraishi¹ and Rana Aslanov², ¹Nexus Clinical Research, St John's, NF, Canada, ²Clinical Epidemiology Department, Faculty of Medicine, Memorial University of Newfoundland, St.John's, NF, Canada
Background/Purpose We aimed to investigate whether the 10-year cardiovascular risk (CV) differs between patients with RA treated with Biologic Disease Modifiers (BDMARDs) and Methotrexate (MTX)…
Abstract Number: 1065 • 2014 ACR/ARHP Annual Meeting
Characteristics of Rheumatoid Arthritis Patients with and without Cardiovascular Diseases – Data from the Ontario Best Practice Research Initiative (OBRI)
Kangping Cui^1,2, Binu Jacob³, Janet E. Pope⁴, Jessica Widdifield⁵, Xiuying Li³, Bindee Kuriya⁶, Pooneh Akhavan⁷ and Claire Bombardier⁶, ¹Faculty of Medicine, University of Toronto, Toronto, ON, Canada, ²University Health Network/Toronto General Hospital Research Institute, Toronto, ON, Canada, ³University Health Network, Toronto General Research Institute, Toronto, ON, Canada, ⁴Medicine, Divsion of Rheumatology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada, ⁵Institute for Clinical Evaluative Science, Toronto, ON, Canada, ⁶Rheumatology, University of Toronto, Toronto, ON, Canada, ⁷Medicine, Mount Sinai Hospital/University of Toronto, Toronto, ON, Canada
Background/Purpose Cardiovascular disease (CVD) is a major comorbidity and the leading cause of death among patients with rheumatoid arthritis (RA). The aim of this study…
Abstract Number: 490 • 2014 ACR/ARHP Annual Meeting
A Randomised Controlled Trial Evaluating the Effect of Humira upon Endothelial Function in ACPA Positive Rheumatoid Arthritis â€“ an Interim Analysis
Stephen Oakley^1,2,3, Niloofar Esmaili⁴, Gabor Major⁴, David Mathers^4,5, Siva Ratnarajah⁶, John van der Kallen⁵, Mark Collins⁶, Marc Toh⁶ and John Glass⁴, ¹Dept of Rheumatology, Newcastle Bone & Joint Institute, Newcastle, Australia, ²School of Medicine & Public Health, University of Newcastle, Newcastle, Australia, ³Clinical Trials Unit, Hunter Medical Research Institute, Newcastle, Australia, ⁴Rheumatology, Newcastle Bone & Joint Institute, Newcastle, Australia, ⁵Rheumatology, Georgetown Arthritis Centre, Newcastle, Australia, ⁶Rheumatology, Private Practice, Newcastle, Australia
Background/Purpose Rheumatoid arthritis (RA) is associated with elevated cardiovascular (CV) risk not explained by traditional risk factors. Increased CV risk may develop prior to the…
Abstract Number: 410 • 2014 ACR/ARHP Annual Meeting
Vascular Endothelial Function Changes during Treatment in Patients with Rheumatoid Arthritis
Johana Zacariaz¹, Eliana Lancioni¹, Tomas Cazenave², Florencia Marengo³, Emilce Edith Schneeberger², Lucas Aparicio⁴, Margarita Morales⁴, Jorge Norscini⁵, Gabriel Waisman⁴, Javier Rosa⁶, Gustavo Citera³ and Enrique R. Soriano⁷, ¹Rheumatology Unit, Internal Medicine Services, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ²Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ³Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, ⁴Hypertension Section, Internal Medicine Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁵Neurology Department, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁶Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁷Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina
Background/Purpose: Rheumatoid Artrhitis (RA) patients have an increased risk for accelerated atherosclerosis. Endothelial dysfunction and arterial stiffness, assessed by measurement of carotid-femoral pulse wave velocity…
Abstract Number: 356 • 2013 ACR/ARHP Annual Meeting
Outcomes Of Patients With Rheumatoid Arthritis and Comorbid Hyperlipidemia
L Rosenblatt¹, JR Curtis², G Yang¹ and T Hebden³, ¹Bristol-Myers Squibb, Plainsboro, NJ, ²University of Alabama at Birmingham, Birmingham, AL, ³Formerly of Bristol-Myers Squibb, Plainsboro, NJ
Background/Purpose: Patients (pts) with RA have an increased prevalence of cardiovascular disease (CVD). Whether due to comorbidity or related to RA medications, many pts with…
Abstract Number: 116 • 2013 ACR/ARHP Annual Meeting
Lack Of Association Between Preclinical Markers For Cardiovascular Disease and Rheumatoid Arthritis-Related Autoimmunity In First-Degree Relatives Without Rheumatoid Arthritis
Jill M. Norris¹, Ryan W. Gan¹, Jan M. Hughes-Austin², Kevin D. Deane³, M. Kristen Demoruelle³, Elaine M. Urbina⁴, Kerrie Moreau⁵, Peter K. Gregersen⁶, Michael H. Weisman⁷ and V. Michael Holers⁸, ¹Epidemiology, Colorado School of Public Health, Aurora, CO, ²Department of Family and Preventive Medicine, University of California, San Diego, La Jolla, CA, ³Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, ⁴Preventive Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁵Medicine, University of Colorado School of Medicine, Aurora, CO, ⁶Genomics and Human Genetics, Feinstein Institute for Medical Research, Manhasset, NY, ⁷Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, ⁸Rheumatology Division, University of Colorado School of Medicine, Aurora, CO
Background/Purpose: Rheumatoid arthritis (RA) is characterized by systemic inflammation and immune dysregulation, including the presence of autoantibodies and elevated inflammatory biomarkers in subjects with classifiable…

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