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Abstracts tagged "Cardiovascular disease and rheumatoid arthritis (RA)"

  • Abstract Number: 2364 • 2017 ACR/ARHP Annual Meeting

    Decrease in Cardiovascular Event Excess Risk in Rheumatoid Arthritis Since 2000: A Meta- Analysis of Controlled Studies

    Elisabeth Filhol1, Charlotte Hua2, Anaiz Nutz3, Françoise Flaisler1, Cédric Lukas4, Jacques Morel5, Bernard Combe5 and Cécile Gaujoux-Viala6, 1Rheumatology, Nîmes University Hospital, Nîmes, France, 2Reumatology, CHU Lapeyronie and Montpellier University, Montpellier, France, 3Rheumatology, Nîmes University Hospital and Montpellier University, Nîmes, France, 4Rheumatology, CHU Lapeyronie and EA2415, Montpellier University, University of Montpellier, France, 5Rheumatology, CHU Lapeyronie and Montpellier University, Montpellier, France, 6Rheumatology, Nîmes University Hospital and EA2415 Montpellier University, Nîmes, France

    Background/Purpose: Compared with the general population, patients with rheumatoid arthritis (RA) have an increased risk of cardiovascular disease or events (CE): stroke, Myocardial Infarction (MI),…
  • Abstract Number: 2368 • 2017 ACR/ARHP Annual Meeting

    Global Circumferential Strain By Assessed a Feature Tracking Cardiac Magnetic Resonance (CMR) Imaging  Was Associated with Myocardial Fibrosis in RA Patients

    Yasuyuki Kobayashi1, Hitomi Kobayashi2, Isamu Yokoe3, Atsuma Nishiwaki4, Akiyuki Kotoku5 and Masami Takei4, 1Advanced Biomedical Imaging Informatics, St.Marianna University School of Medicine, Kawasaki, Japan, 2Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 3Rheumatology, Kyoundo Hospital, Sasaki Institute, Tokyo, Japan, 4Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, 5Advanced Biomedical Imaging Informatics, St. Marianna University School of Medicine, Kawasaki, Japan

    Background/Purpose: Individuals with RA have a 1.5-2.0 fold higher risk of developing congestive heart failure (CHF) than the general population. It is important to understand…
  • Abstract Number: 2417 • 2017 ACR/ARHP Annual Meeting

    Occult Coronary Plaque Presence and Burden Predict Cardiovascular Events in Patients with Rheumatoid Arthritis

    George Karpouzas1, Joel Estis2, John Todd2 and Matthew Budoff3, 1Division of Rheumatology, Harbor-UCLA Medical Center, Torrance, CA, 2Singulex, Alameda, California, Alameda, CA, 3Cardiology, Harbor-UCLA Medical Center, Torrance, CA

    Background/Purpose: Patients with Rheumatoid Arthritis (RA) experience higher cardiovascular (CV) morbidity compared to controls. Coronary computed tomography angiography (CCTA) accurately detects plaque presence, burden and…
  • Abstract Number: 423 • 2016 ACR/ARHP Annual Meeting

    Cardiovascular Risk and Lipid Screening in Rheumatoid Arthritis Patients in a University Rheumatology Practice: Quality Improvement Project

    Diana Mosteanu, Xuan Wang, Donald Kimpel and Janet Lewis, University of Virginia, Charlottesville, VA

    Background/Purpose: Meta-analyses of observational studies showed that RA patients’ morbidity and mortality risks stemming from cardiovascular (CV) causes were, respectively, close to 50% and 60%…
  • Abstract Number: 1465 • 2016 ACR/ARHP Annual Meeting

    Utility of Relative Cardiovascular Risk Score Scales in Patients UNDER the Age of 50 and Its Association with the Presence of Carotid Atherosclerosis in the Ultrasound

    Andrea Zacarias1, Carmen Gomez Vaquero2, Francisco Javier Narváez3, Miguel Angel González-Gay4, Alfonso Corrales5, Carlos González-Juanatey6, Javier Llorca7 and Joan Miquel Nolla8, 1Hospital Universitari de Bellvitge, Barcelona, Spain, 2Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 3Rheumatology, Hospital Universitario de Bellvitge-IDIBELL, L’Hospitalet de Llobregat, Barcelona, Spain, 4Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, University of Cantabria, Santander, Spain, 5Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, 6Cardiology Division, Hospital Xeral-Calde, Lugo, Spain, 7Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), IDIVAL, Santander, Spain, 8Rheumatology, Bellvitge University Hospital, Barcelona, Spain

    Background/Purpose: Rheumatoid Arthritis (RA) is associated with a greater cardiovascular mortality than the general population of the same age and gender. Cardiovascular events prediction scales,…
  • Abstract Number: 1466 • 2016 ACR/ARHP Annual Meeting

    Cardiovascular Risk Assessment in Persons with Rheumatoid Arthritis: A Correlative Study of Non-Invasive Arterial Health Testing with the Inflammatory Burden of Disease

    Erin Scanlon1, Rekha Mankad2, Cynthia S. Crowson3, Iftikhar Kullo4, Sharon Mulvagh2, Eric L. Matteson1, Zoran Kvrgic1 and John M. Davis III5, 1Rheumatology, Mayo Clinic, Rochester, MN, 2Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 3Health Sciences Research, Mayo Clinic, Rochester, MN, 4Department of Internal Medicine, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 5Division of Rheumatology, Mayo Clinic, Rochester, MN

    Background/Purpose:  Persons with rheumatoid arthritis (RA) have increased morbidity and mortality attributable to atherosclerotic cardiovascular disease (ASCVD) events. It is unknown how presence of subclinical…
  • Abstract Number: 1472 • 2016 ACR/ARHP Annual Meeting

    Comparison Between Carotid Plaque and Carotid Intima-Media Thickness to Detect Subclinical Atherosclerosis in Rheumatoid Arthritis

    Lucia C. Domínguez-Casas1, Leyre Riancho-Zarrabeitia1, Nuria Vegas-Revenga2, Alfonso Corrales1, Carlos Fernández Díaz1, Montserrat Santos-Gómez3, Virginia Portilla2, Patrick H Dessein4, Ricardo Blanco1 and Miguel Angel Gonzalez-Gay1, 1Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, 3Rheumatology, Hospital Can Misses, Ibiza, Spain, 4Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

    Background/Purpose:   Carotid plaque (CP) detected by ultrasonography and carotid intima-media thickness (cIMT) are useful surrogate markers for subclinical atherosclerosis and good predictors of cardiovascular…
  • Abstract Number: 1476 • 2016 ACR/ARHP Annual Meeting

    Diastolic Dysfunction in Patients with Rheumatoid Arthritis: Predictors of Longitudinal Progression over Five Years

    John M. Davis III1, Grace Lin2, Jae Oh3, Sara J. Achenbach4, Terry M. Therneau5, Eric L. Matteson6, Elena Myasoedova6, Sherine E. Gabriel7 and Cynthia S. Crowson8, 1Division of Rheumatology, Mayo Clinic, Rochester, MN, 2General Internal Medicine, University of California San Francisco, San Francisco, CA, 3ICON Late Phase and Outcomes Research, San Francisco, CA, 4Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 5Biostatistics, Mayo Clinic, Rochester, MN, 6Rheumatology, Mayo Clinic, Rochester, MN, 7Dean's Office, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, 8Health Sciences Research, Mayo Clinic, Rochester, MN

    Background/Purpose:   The impairment of left ventricular (LV) relaxation and passive filling, known as diastolic dysfunction, undergirds the development of heart failure in patients with…
  • Abstract Number: 1491 • 2016 ACR/ARHP Annual Meeting

    M-Ficolin and MAp44 As Potential Markers of Subclinical Cardiovascular Comorbidity; Cardiac Evaluation By Coronary Computer Tomography and Myocardial Deformation of Left Ventricle in Early Rheumatoid Arthritis Patients

    Ida G. Louw1, Christian G. Ammitzböll2, Brian Bridal Løgstrup3, Jesper Blegvad-Nissen4, Grazina Urbonaviciene4, Trine Bay Laurberg4, Mette Herly5, Agnete H. Nielsen4, Steffen Thiel6 and Torkell Ellingsen5, 1University of Southern Denmark, Odense, DK, Odense, Denmark, 2Department of Rheumatology, Aarhus University Hospital, Aarhus, DK, Aarhus, Denmark, 3Department of Cardiology, Skejby, Aarhus University Hospital, Aarhus, DK, Aarhus, Denmark, 4Diagnostic Centre, University Research Clinic for Innovative Patient Pathways, Silkeborg Regional Hospital, DK, Silkeborg, Denmark, 5Department of Rheumatology, Odense University Hospital, Odense, DK, Odense, Denmark, 6Institute of Biomedicine, Aarhus University, Aarhus, DK, Aarhus, Denmark

    Background/Purpose:  79 DMARD-naïve RA patients with a disease duration < 6 months were included from an inception cohort. Clinical variables, plasma- and serum-M-ficolin and MAp44…
  • Abstract Number: 1990 • 2016 ACR/ARHP Annual Meeting

    Increased Risk of Cardiovascular Events in Patients with Rheumatoid Arthritis over a 15 Year Time Period That Is Comparable to Type 2 Diabetes

    Rabia Agca1,2, Luuk H.G.A. Hopman2, Vokko P. van Halm3, Mike J.L. Peters4, Jacqueline M. Dekker5, Giel Nijpels5, Coen D.A. Stehouwer6, Yvo M. Smulders4, Alexandre E. Voskuyl1, Maarten Boers1, Willem F. Lems7 and Mike T. Nurmohamed2,8, 1Rheumatology, Amsterdam Rheumatology and immunology Center, Location VU University Medical Center, Amsterdam, Netherlands, 2Rheumatology, Amsterdam Rheumatology and immunology Center, Location Reade, Amsterdam, Netherlands, 3Cardiology, VU University Medical Center, Amsterdam, Netherlands, 4Internal Medicine, VU University Medical Center, Amsterdam, Netherlands, 5EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands, 6Internal Medicine, Department of Internal Medicine, Maastricht University Medical Centre, Maastricht, Netherlands, 7Rheumatology, Amsterdam Rheumatology and immunology Center, location VU University Medical Center, Amsterdam, Netherlands, Amsterdam, Netherlands, 8Rheumatology, Amsterdam Rheumatology and immunology Center, Location VU University Medical Center, Amsterdam, Netherlands, Amsterdam, Netherlands

    Background/Purpose:  recent cohort studies with long term follow up studying this risk are scarce.We report the results of a 15 year observational cohort study comparing…
  • Abstract Number: 1611 • 2015 ACR/ARHP Annual Meeting

    Gene Expression Profiling Reflects Increased Expression of Coronary Artery Disease Associated Genes in a Case-Control Matched Study of Patient with Rheumatoid Arthritis

    Erica Peart1, Kim Huffman2, William E. Kraus3, Phil Beineke4, Jim Wingrove4 and Steve Rosenberg4, 1Rheumatology, Duke University Medical Center, Durham, NC, 2Durham Veterans Affairs Medical Center, Durham, NC, 3Duke Pepper Center, Durham, NC, 4CardioDx, Redwood City, CA

    Background/Purpose: Peripheral blood gene expression profiling has been used to identify gene signatures which reflect a variety of pathologic conditions.  The CorusCAD¨ test is a…
  • Abstract Number: 1615 • 2015 ACR/ARHP Annual Meeting

    Lack of Replication of the Association Between Anti-Citrullinated Fibrinogen and Subclinical Atherosclerosis in Patients with Rheumatoid Arthritis

    Ariana Montes1, Alfonso Corrales2, Manuel Calaza3, Raquel López-Mejías4, José Antonio Parra5, Miguel Angel Gonzalez-Gay6 and Antonio Gonzalez7, 1Laboratorio Investigacion 10 and Rheumatology Unit, Instituto Investigacion Sanitaria- Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain, 2Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, 3Laboratorio Investigacion 10 and Rheumatology Unit. Instituto Investigacion Sanitaria.Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain, 4Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, Rheumatology Division, IDIVAL, Santander, Spain, 5Radiology Division, Hospital Universitario Marqués de Valdecilla, Santander, Spain, 6Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, 7Instituto Investigacion Sanitaria-Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain

    Background/Purpose: A recent study has suggested that the excess cardiovascular (CV) risk observed in patients with rheumatoid arthritis (RA) could be partially explained by immune-complexes…
  • Abstract Number: 1673 • 2015 ACR/ARHP Annual Meeting

    The Transcription Factor Nuclear Protein Transcriptional Regulator 1 May Contribute to Increased Risk of Cardiovascular Disease in Patients with Rheumatoid Arthritis

    Ida G. Fostad1, Jon Roger Eidet2, Torstein Lyberg2, Ole K. Olstad2, Tor Paaske Utheim1,2, Knut Mikkelsen3, Allan Wiik4 and Ivana Hollan3, 1Department of Oral Biology, Faculty of Dentistry, University of Oslo, Oslo, Norway, 2Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway, 3Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Norway, 4Clinical Biochem/Immunology, Statens Serum Institute, Copenhagen S, Denmark

    Background/Purpose: The cause of accelerated atherosclerosis in rheumatoid arthritis (RA) is still unclear and appears to be multifactorial. Besides the traditional risk factors, also RA-specific…
  • Abstract Number: 2130 • 2015 ACR/ARHP Annual Meeting

    Primary Prevention of Myocardial Infarction in Rheumatoid Arthritis Using Low-Dose Aspirin: A Case-Crossover Study

    Josefina Durán Santa Cruz1, Yuqing Zhang2 and David T. Felson3, 1Department of Rheumatology, Pontificia Universidad Católica de Chile School of Medicine, Santiago, Chile, 2Clinical Epidemilogy and Training Unit, Boston University School of Medicine, Boston, MA, 3Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA

    Background/Purpose: Subjects with rheumatoid arthritis (RA) are at a higher risk of developing cardiovascular (CV) disease which is the leading cause of death in subjects…
  • Abstract Number: 1298 • 2015 ACR/ARHP Annual Meeting

    Advocating for Rheumatoid Arthritis and Cardiovascular Health (ARCH): A Collaborative and Systems-Based Approach to Improve Access to Care

    Barbara Goldstein and JoAnn Zell, Medicine, National Jewish Health, Denver, CO

    Background/Purpose: Patients with rheumatoid arthritis (RA) have an increased risk of cardiovascular disease (CVD) as compared to the general population. The European League Against Rheumatism…
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