Abstracts tagged "Cardiovascular disease and rheumatoid arthritis (RA)"

Abstract Number: 2364 • 2017 ACR/ARHP Annual Meeting
Decrease in Cardiovascular Event Excess Risk in Rheumatoid Arthritis Since 2000: A Meta- Analysis of Controlled Studies
Elisabeth Filhol¹, Charlotte Hua², Anaiz Nutz³, Françoise Flaisler¹, Cédric Lukas⁴, Jacques Morel⁵, Bernard Combe⁵ and Cécile Gaujoux-Viala⁶, ¹Rheumatology, Nîmes University Hospital, Nîmes, France, ²Reumatology, CHU Lapeyronie and Montpellier University, Montpellier, France, ³Rheumatology, Nîmes University Hospital and Montpellier University, Nîmes, France, ⁴Rheumatology, CHU Lapeyronie and EA2415, Montpellier University, University of Montpellier, France, ⁵Rheumatology, CHU Lapeyronie and Montpellier University, Montpellier, France, ⁶Rheumatology, Nîmes University Hospital and EA2415 Montpellier University, Nîmes, France
Background/Purpose: Compared with the general population, patients with rheumatoid arthritis (RA) have an increased risk of cardiovascular disease or events (CE): stroke, Myocardial Infarction (MI),…
Abstract Number: 2368 • 2017 ACR/ARHP Annual Meeting
Global Circumferential Strain By Assessed a Feature Tracking Cardiac Magnetic Resonance (CMR) Imaging Was Associated with Myocardial Fibrosis in RA Patients
Yasuyuki Kobayashi¹, Hitomi Kobayashi², Isamu Yokoe³, Atsuma Nishiwaki⁴, Akiyuki Kotoku⁵ and Masami Takei⁴, ¹Advanced Biomedical Imaging Informatics, St.Marianna University School of Medicine, Kawasaki, Japan, ²Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ³Rheumatology, Kyoundo Hospital, Sasaki Institute, Tokyo, Japan, ⁴Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ⁵Advanced Biomedical Imaging Informatics, St. Marianna University School of Medicine, Kawasaki, Japan
Background/Purpose: Individuals with RA have a 1.5-2.0 fold higher risk of developing congestive heart failure (CHF) than the general population. It is important to understand…
Abstract Number: 2417 • 2017 ACR/ARHP Annual Meeting
Occult Coronary Plaque Presence and Burden Predict Cardiovascular Events in Patients with Rheumatoid Arthritis
George Karpouzas¹, Joel Estis², John Todd² and Matthew Budoff³, ¹Division of Rheumatology, Harbor-UCLA Medical Center, Torrance, CA, ²Singulex, Alameda, California, Alameda, CA, ³Cardiology, Harbor-UCLA Medical Center, Torrance, CA
Background/Purpose: Patients with Rheumatoid Arthritis (RA) experience higher cardiovascular (CV) morbidity compared to controls. Coronary computed tomography angiography (CCTA) accurately detects plaque presence, burden and…
Abstract Number: 1472 • 2016 ACR/ARHP Annual Meeting
Comparison Between Carotid Plaque and Carotid Intima-Media Thickness to Detect Subclinical Atherosclerosis in Rheumatoid Arthritis
Lucia C. Domínguez-Casas¹, Leyre Riancho-Zarrabeitia¹, Nuria Vegas-Revenga², Alfonso Corrales¹, Carlos Fernández Díaz¹, Montserrat Santos-Gómez³, Virginia Portilla², Patrick H Dessein⁴, Ricardo Blanco¹ and Miguel Angel Gonzalez-Gay¹, ¹Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ²Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ³Rheumatology, Hospital Can Misses, Ibiza, Spain, ⁴Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa
Background/Purpose: Carotid plaque (CP) detected by ultrasonography and carotid intima-media thickness (cIMT) are useful surrogate markers for subclinical atherosclerosis and good predictors of cardiovascular…
Abstract Number: 1476 • 2016 ACR/ARHP Annual Meeting
Diastolic Dysfunction in Patients with Rheumatoid Arthritis: Predictors of Longitudinal Progression over Five Years
John M. Davis III¹, Grace Lin², Jae Oh³, Sara J. Achenbach⁴, Terry M. Therneau⁵, Eric L. Matteson⁶, Elena Myasoedova⁶, Sherine E. Gabriel⁷ and Cynthia S. Crowson⁸, ¹Division of Rheumatology, Mayo Clinic, Rochester, MN, ²General Internal Medicine, University of California San Francisco, San Francisco, CA, ³ICON Late Phase and Outcomes Research, San Francisco, CA, ⁴Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ⁵Biostatistics, Mayo Clinic, Rochester, MN, ⁶Rheumatology, Mayo Clinic, Rochester, MN, ⁷Dean's Office, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, ⁸Health Sciences Research, Mayo Clinic, Rochester, MN
Background/Purpose: The impairment of left ventricular (LV) relaxation and passive filling, known as diastolic dysfunction, undergirds the development of heart failure in patients with…
Abstract Number: 1491 • 2016 ACR/ARHP Annual Meeting
M-Ficolin and MAp44 As Potential Markers of Subclinical Cardiovascular Comorbidity; Cardiac Evaluation By Coronary Computer Tomography and Myocardial Deformation of Left Ventricle in Early Rheumatoid Arthritis Patients
Ida G. Louw¹, Christian G. Ammitzböll², Brian Bridal Løgstrup³, Jesper Blegvad-Nissen⁴, Grazina Urbonaviciene⁴, Trine Bay Laurberg⁴, Mette Herly⁵, Agnete H. Nielsen⁴, Steffen Thiel⁶ and Torkell Ellingsen⁵, ¹University of Southern Denmark, Odense, DK, Odense, Denmark, ²Department of Rheumatology, Aarhus University Hospital, Aarhus, DK, Aarhus, Denmark, ³Department of Cardiology, Skejby, Aarhus University Hospital, Aarhus, DK, Aarhus, Denmark, ⁴Diagnostic Centre, University Research Clinic for Innovative Patient Pathways, Silkeborg Regional Hospital, DK, Silkeborg, Denmark, ⁵Department of Rheumatology, Odense University Hospital, Odense, DK, Odense, Denmark, ⁶Institute of Biomedicine, Aarhus University, Aarhus, DK, Aarhus, Denmark
Background/Purpose: 79 DMARD-naïve RA patients with a disease duration < 6 months were included from an inception cohort. Clinical variables, plasma- and serum-M-ficolin and MAp44…
Abstract Number: 1990 • 2016 ACR/ARHP Annual Meeting
Increased Risk of Cardiovascular Events in Patients with Rheumatoid Arthritis over a 15 Year Time Period That Is Comparable to Type 2 Diabetes
Rabia Agca^1,2, Luuk H.G.A. Hopman², Vokko P. van Halm³, Mike J.L. Peters⁴, Jacqueline M. Dekker⁵, Giel Nijpels⁵, Coen D.A. Stehouwer⁶, Yvo M. Smulders⁴, Alexandre E. Voskuyl¹, Maarten Boers¹, Willem F. Lems⁷ and Mike T. Nurmohamed^2,8, ¹Rheumatology, Amsterdam Rheumatology and immunology Center, Location VU University Medical Center, Amsterdam, Netherlands, ²Rheumatology, Amsterdam Rheumatology and immunology Center, Location Reade, Amsterdam, Netherlands, ³Cardiology, VU University Medical Center, Amsterdam, Netherlands, ⁴Internal Medicine, VU University Medical Center, Amsterdam, Netherlands, ⁵EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands, ⁶Internal Medicine, Department of Internal Medicine, Maastricht University Medical Centre, Maastricht, Netherlands, ⁷Rheumatology, Amsterdam Rheumatology and immunology Center, location VU University Medical Center, Amsterdam, Netherlands, Amsterdam, Netherlands, ⁸Rheumatology, Amsterdam Rheumatology and immunology Center, Location VU University Medical Center, Amsterdam, Netherlands, Amsterdam, Netherlands
Background/Purpose: recent cohort studies with long term follow up studying this risk are scarce.We report the results of a 15 year observational cohort study comparing…
Abstract Number: 423 • 2016 ACR/ARHP Annual Meeting
Cardiovascular Risk and Lipid Screening in Rheumatoid Arthritis Patients in a University Rheumatology Practice: Quality Improvement Project
Diana Mosteanu, Xuan Wang, Donald Kimpel and Janet Lewis, University of Virginia, Charlottesville, VA
Background/Purpose: Meta-analyses of observational studies showed that RA patients’ morbidity and mortality risks stemming from cardiovascular (CV) causes were, respectively, close to 50% and 60%…
Abstract Number: 1465 • 2016 ACR/ARHP Annual Meeting
Utility of Relative Cardiovascular Risk Score Scales in Patients UNDER the Age of 50 and Its Association with the Presence of Carotid Atherosclerosis in the Ultrasound
Andrea Zacarias¹, Carmen Gomez Vaquero², Francisco Javier Narváez³, Miguel Angel González-Gay⁴, Alfonso Corrales⁵, Carlos González-Juanatey⁶, Javier Llorca⁷ and Joan Miquel Nolla⁸, ¹Hospital Universitari de Bellvitge, Barcelona, Spain, ²Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, ³Rheumatology, Hospital Universitario de Bellvitge-IDIBELL, L’Hospitalet de Llobregat, Barcelona, Spain, ⁴Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, University of Cantabria, Santander, Spain, ⁵Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, ⁶Cardiology Division, Hospital Xeral-Calde, Lugo, Spain, ⁷Department of Epidemiology and Computational Biology, School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), IDIVAL, Santander, Spain, ⁸Rheumatology, Bellvitge University Hospital, Barcelona, Spain
Background/Purpose: Rheumatoid Arthritis (RA) is associated with a greater cardiovascular mortality than the general population of the same age and gender. Cardiovascular events prediction scales,…
Abstract Number: 1466 • 2016 ACR/ARHP Annual Meeting
Cardiovascular Risk Assessment in Persons with Rheumatoid Arthritis: A Correlative Study of Non-Invasive Arterial Health Testing with the Inflammatory Burden of Disease
Erin Scanlon¹, Rekha Mankad², Cynthia S. Crowson³, Iftikhar Kullo⁴, Sharon Mulvagh², Eric L. Matteson¹, Zoran Kvrgic¹ and John M. Davis III⁵, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Cardiovascular Diseases, Mayo Clinic, Rochester, MN, ³Health Sciences Research, Mayo Clinic, Rochester, MN, ⁴Department of Internal Medicine, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, ⁵Division of Rheumatology, Mayo Clinic, Rochester, MN
Background/Purpose: Persons with rheumatoid arthritis (RA) have increased morbidity and mortality attributable to atherosclerotic cardiovascular disease (ASCVD) events. It is unknown how presence of subclinical…
Abstract Number: 1591 • 2015 ACR/ARHP Annual Meeting
A Low Adiponectin Level in Rheumatoid Arthritis Is Associated with Coronary Artery Disease
Jon Roger Eidet¹, Ida G. Fostad², Kelly J. Shields³, Torstein Lyberg¹, Tor Paaske Utheim¹, Anita Kåss⁴, Knut Mikkelsen⁵, Terje Veel⁶, Kjell Saatvedt⁷, Morten Wang Fagerland⁸, Matthew Liang⁹ and Ivana Hollan⁵, ¹Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway, ²Department of Oral Biology, Faculty of Dentistry, University of Oslo, Oslo, Norway, ³Medicine, Lupus Center of Excellence / Allegheny Health Network, Pittsburgh, PA, ⁴Rheumatology, Betanien Hospital, Skien, Norway, ⁵Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Norway, ⁶Department of Cardiac Surgery, Feiring Heart Clinic, Feiring, Norway, ⁷Department of Cardiothoracic Surgery, Oslo University Hospital, Oslo, Norway, ⁸Department of Biostatistics, Oslo University Hospital, Oslo, Norway, ⁹Department of Rheumatology, Brigham and Women’ s Hospital, Boston, Boston, MA
Background/Purpose: Adipokines exert pleiotropic actions, including immunoregulatory and matrix degrading effects. There is evidence of adipokine involvement in the pathogenesis of cardiovascular (CV) disease as…
Abstract Number: 1592 • 2015 ACR/ARHP Annual Meeting
Sex Differences in Cardiovascular Risk Factors and Event Rates in Patients with Rheumatoid Arthritis – Data from 13 Rheumatology Centers
Silvia Rollefstad¹, Eirik Ikdahl¹, Cynthia S. Crowson², Sherine Gabriel³, George D. Kitas⁴, Piet L van Riel⁵, Anne Grete Semb⁶ and ATACC-RA, ¹Preventive Cardio-Rheuma Clinic, Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Health Sciences Research, Mayo Clinic, Rochester, MN, ³Division of Rheumatology; Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ⁴The Dudley Group of Hospitals NHS Foundation Trust, Dudley, United Kingdom, ⁵Scientific Institute for Quality of Healthcare, Radboud University Medical Center, Nijmegen, Netherlands, ⁶Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: Patients with rheumatoid arthritis (RA) have an excess risk of cardiovascular disease (CVD). There is a clear female to male preponderance of RA. In…
Abstract Number: 1593 • 2015 ACR/ARHP Annual Meeting
Telomere Length and Cardiovascular Risk in Rheumatoid Arthritis
Michelle J. Ormseth¹, Joseph F. Solus², Annette M. Oeser³, Aihua Bian⁴, Tebeb Gebretsadik⁴, Ayumi Shintani⁵, Paolo Raggi⁶ and C Michael Stein⁵, ¹Department of Medicine, Division of Rheumatology, Vanderbilt University, Nashville, TN, ²Clinical Pharmacology, Vanderbilt University, Nashville, TN, ³Medicine, Vanderbilt University, Nashville, TN, ⁴Biostatistics, Vanderbilt University, Nashville, TN, ⁵Vanderbilt University, Nashville, TN, ⁶Emory University, Atlanta, GA
Background/Purpose: Telomeres protect against DNA damage and shorten with each cell division; their length may be a marker of cardiovascular and overall biological aging. Patients…
Abstract Number: 1595 • 2015 ACR/ARHP Annual Meeting
Impaired Coronary Flow Reserve in Rheumatoid Arthritis: A Robust Indicator of Cardiac Structure Associated with Systemic Inflammation and Rheumatoid Arthritis Treatments
Isabelle Amigues¹, Jon T. Giles¹, Sabahat Bokhari², Afshin Zartoshti³, Richard Weinberg², Cesare Russo⁴ and Joan Bathon³, ¹Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, ²Cardiology, Columbia University Medical Center, NY, NY, ³Rheumatology, Columbia University Medical Center, NY, NY, ⁴Division of Cardiology, Columbia University, College of Physicians & Surgeons, New York, NY
Background/Purpose: Myocardial microvascular dysfunction may precede or coexist with coronary atherosclerosis and heart failure, two conditions over-represented in RA. Coronary flow reserve (CFR) offers an…
Abstract Number: 1611 • 2015 ACR/ARHP Annual Meeting
Gene Expression Profiling Reflects Increased Expression of Coronary Artery Disease Associated Genes in a Case-Control Matched Study of Patient with Rheumatoid Arthritis
Erica Peart¹, Kim Huffman², William E. Kraus³, Phil Beineke⁴, Jim Wingrove⁴ and Steve Rosenberg⁴, ¹Rheumatology, Duke University Medical Center, Durham, NC, ²Durham Veterans Affairs Medical Center, Durham, NC, ³Duke Pepper Center, Durham, NC, ⁴CardioDx, Redwood City, CA
Background/Purpose: Peripheral blood gene expression profiling has been used to identify gene signatures which reflect a variety of pathologic conditions. The CorusCAD¨ test is a…

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