Abstracts tagged "Bone marrow"

Abstract Number: 271 • 2012 ACR/ARHP Annual Meeting
Bone Marrow Lesions in Knees with Osteoarthritis: Can Parameters From Dynamic Contrast Enhancement Predict Change in Bone Marrow Lesion Volume or Knee Pain Change?
Andrew D. Gait¹, Timothy F. Cootes¹, Elizabeth J. Marjanovic¹, Matthew J. Parkes², Charles E. Hutchinson³ and David T. Felson⁴, ¹Imaging Sciences, School of Cancer & Enabling Sciences, University of Manchester, Manchester, United Kingdom, ²Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom, ³Warwick Medical School, University of Warwick, Coventry, United Kingdom, ⁴ARC Epidemiology Unit, University of Manchester, Manchester, United Kingdom
Background/Purpose: Dynamic contrast enhancement is a powerful tool for highlighting features of a medical image which may not otherwise be seen on "static" scans. While…
Abstract Number: 2612 • 2012 ACR/ARHP Annual Meeting
Localisation of Bone Marrow Edema in Sacroiliac Joints in Spondyloarthritis Patients: Does the Site of Lesions Change Over a 3-Month Period?
Manouk de Hooge¹, Rosaline van den Berg¹, Monique Reijnierse², Victoria Navarro-Compán¹, Floris van Gaalen¹, Tom Huizinga¹ and Désirée van der Heijde¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Radiology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: A positive MRI at baseline is a strong predictor for a positive follow-up MRI1. But many questions about the volatility of the lesions over…
Abstract Number: 2583 • 2012 ACR/ARHP Annual Meeting
Bone Structure and Perfusion Quantification of Bone Marrow Edema and Pannus Tissue Areas in the Wrist of Patients with RA
Jose R. Teruel Antolin¹, Andrew J. Burghardt², Julien Rivoire¹, Waraporn Srikhum¹, Susan M. Noworolski³, Thomas M. Link¹, John B. Imboden⁴ and Xiaojuan Li⁵, ¹Musculoskeletal Quantitative Imaging Research Group, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, ²Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, ³Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, ⁴Department of Medicine, Division of Rheumatology, UCSF, San Francisco, CA, ⁵Department of Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA
Background/Purpose: Bone marrow edema (BME) has been suggested as a strong predictor for erosive progression in RA joints, however, no previous studies examined the bone…
Abstract Number: 2142 • 2012 ACR/ARHP Annual Meeting
Magnetic Resonance Imaging-Proven Osteitis At Baseline Predicts the Early Rheumatoid Arthritis Patients Who Will Develop Rapid Radiographic Progression: MRI Is Beneficial to Find the Window of Opportunity in Early RA
Mami Tamai¹, Yoshikazu Nakashima², Takahisa Suzuki³, Yoshiro Horai², Akitomo Okada⁴, Junko Kita⁴, Shin-ya Kawashiri², Naoki Iwamoto⁴, Kunihiro Ichinose⁵, Kazuhiko Arima⁴, Hideki Nakamura¹, Tomoki Origuchi⁶, Masataka Uetani⁷, Kiyoshi Aoyagi⁸, Katsumi Eguchi⁹ and Atsushi Kawakami², ¹Department of Immunology and Rheumatology, Nagasaki University, Nagasaki, Japan, ²Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ³Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁴Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁵Department of Immunology and Rheumatology, Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁶Department of Health Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁷Department of Radiology and Radiation Research, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁸Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁹Sasebo City General Hospital, Sasebo, Nagasaki, Japan
Background/Purpose: Window of opportunity exists in the earlier phase of rheumatoid arthritis (RA), thus, early recognition of the RA patients who will develop rapid radiographic…
Abstract Number: 2135 • 2012 ACR/ARHP Annual Meeting
Trabecular Bone Texture parameters are Correlated with Magnetic Resonance Imaging (MRI) bone Edema At Hand and Wrist in Active Rheumatoid Arthritis (RA)
Thao Pham¹, Sophie Trijau¹, Roland Chapurlat², Damien Loeuille³, Thierry Schaeverbeke⁴, Christian Roux⁵, Claude-Laurent Benhamou⁶, Olivier Vittecoq⁷, Jean Sibilia⁸, Frederic Mistretta⁹ and Cécile Hacquard-Bouder¹⁰, ¹Rheumatology Department, Sainte Marguerite Hospital, Marseille, France, ²Hôpital Edouard Herriot, Lyon, France, ³Rheumatology, CHU Brabois, Vandoeuvre les Nancy, France, ⁴Service de Rhumatologie, Groupe Hospitalier Pellegrin, Bordeaux, France, ⁵Rheumatology, Paris Descartes University, Paris, France, ⁶Centre Hospitalier Régional d'Orléans, Orleans, France, ⁷Rheumatology, Rouen University Hospital & Inserm905, University of Rouen, Rouen Cedex, France, ⁸Rheumatology, CHU Hautepierre, Strasbourg, France, ⁹Lyon, France, ¹⁰Abbott France, Rungis, France
Background/Purpose: In RA, bone marrow edema (BME) is predictive of erosive progression. Bone erosions are assumed to appear through activation of local bone resorption mechanisms,…
Abstract Number: 2112 • 2012 ACR/ARHP Annual Meeting
Combination of Magnetic Resonance Imaging (MRI)-Proven Osteitis with 2010 RA Classification Criteria Improves the Diagnostic Probability of Rheumatoid Arthritis (RA)
Mami Tamai¹, Yoshikazu Nakashima¹, Takahisa Suzuki¹, Yoshiro Horai², Akitomo Okada², Junko Kita², Shin-ya Kawashiri³, Naoki Iwamoto², Kunihiro Ichinose⁴, Kazuhiko Arima², Hideki Nakamura⁵, Tomoki Origuchi⁶, Masataka Uetani⁷, Kiyoshi Aoyagi⁸, Katsumi Eguchi⁹ and Atsushi Kawakami³, ¹Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ²Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ³Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁴Department of Immunology and Rheumatology, Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁵Department of Immunology and Rheumatology, Nagasaki University, Nagasaki, Japan, ⁶Department of Health Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁷Department of Radiology and Radiation Research, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁸Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁹Sasebo City General Hospital, Sasebo, Nagasaki, Japan
Background/Purpose: In the articles of 2010 rheumatoid arthritis (RA) classification criteria, it is stated that additional evidence of joint injury from other imaging techniques such…
Abstract Number: 1117 • 2012 ACR/ARHP Annual Meeting
Association Between Hip Bone Marrow Lesions (BMLs) and Bone Mineral Density: A Cross-Sectional and Longitudinal Population-Based Study
Harbeer Ahedi¹, Dawn Dore¹, Leigh Blizzard², Flavia Cicuttini³ and Graeme Jones⁴, ¹Musculoskeletal Unit, Menzies Research institute Tasmania, University of Tasmania, Hobart, 7000, Australia, ²Statistics, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia, ³Department of Epidemiology and Preventive Medicine, Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, 3004, Australia, ⁴Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia
Background/Purpose: Bone marrow lesions (BMLs) have been identified one of the key pathologic features in knee osteoarthritis (OA) 1. However, there is limited data on…
Abstract Number: 1061 • 2012 ACR/ARHP Annual Meeting
Generation of Myeloid-Derived Suppressor Cells in Vitro From Murine Bone Marrow Precursors
Julia Kurko¹, Beata Tryniszewska¹, Tibor A. Rauch¹, Colt Egelston², Tibor T. Glant¹ and Katalin Mikecz¹, ¹Orthopedic Surgery, Rush University Medical Center, Chicago, IL, ²Immunology, Rush University Medical Center, Chicago, IL
Background/Purpose: Myeloid-derived suppressor cells (MDSCs) are innate immune cells that expand under pathological conditions (such as cancer and autoimmune diseases) in response to local growth…
Abstract Number: 1028 • 2012 ACR/ARHP Annual Meeting
Semi-Quantitative Assessment of Bone Marrow Edema and Synovitis-Effusion in Osteoarthritis with the Knee Inflammation MRI Scoring System: A Target Lesion Based Methodology
Walter P. Maksymowych¹, Ulrich Weber², Marcus Pianta³ and Robert GW Lambert³, ¹Department of Medicine, University of Alberta, Edmonton, AB, Canada, ²Rheumatology, Balgrist University Hospital, Zurich, Switzerland, ³Radiology, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Current MRI scoring methods for assessment of bone marrow lesions (BML) in the knee of patients with osteoarthritis rely on a complex subdivision of…

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