Abstracts tagged "Bone density"

Abstract Number: 2299 • 2018 ACR/ARHP Annual Meeting
Subgroup Analysis of the Effect of Denosumab Compared with Risedronate on Percentage Change in Lumbar Spine Bone Mineral Density at 24 Months in Glucocorticoid-Treated Individuals
Kenneth Saag¹, Nicola Pannacciulli², Piet Geusens³, Jonathan D. Adachi⁴, Eric Lespessailles⁵, Jorge Malouf⁶, Bente Langdahl⁷, Peter W. Butler², Xiang Yin² and Willem F. Lems⁸, ¹University of Alabama, Birmingham, AL, ²Amgen Inc., Thousand Oaks, CA, ³Maastricht University, Maastricht, Netherlands, ⁴McMaster University, Hamilton, ON, Canada, ⁵University Hospital Orleans, Orleans, France, ⁶Hospital San Pablo, Barcelona, Spain, ⁷Aarhus University, Aarhus, Denmark, ⁸VU University Medical Centre, Amsterdam, Netherlands
Background/Purpose: We previously demonstrated that denosumab increased lumbar spine and total hip bone mineral density (BMD) significantly more than risedronate at 12 and 24 months…
Abstract Number: 2300 • 2018 ACR/ARHP Annual Meeting
Compliance with Screening and Supplementation Guidelines for Glucocorticoid-Induced Osteoporosis, How Bad Did We Do This Time?
John Zawidniak¹ and John Waterman², ¹Rheumatology, University of Connecticut, Farmington, CT, ²Rheumatology, Connecticut VA Healthcare System, Newington, CT
Background/Purpose: Glucocorticoid-induced osteoporosis (GIOP) is a well-established and well-studied phenomenon that is a sequela of the treatment of many inflammatory diseases. Many studies over the…
Abstract Number: 2302 • 2018 ACR/ARHP Annual Meeting
Forearm Bone Mineral Density and Fracture Incidence in Postmenopausal Women with Osteoporosis
Nelson B. Watts¹, Robin K. Dore², Sanford Baim³, Gary Hattersley⁴, Greg Williams⁵, Yamei Wang⁴, Tamara D. Rozental⁶ and Meryl S. LeBoff⁷, ¹Mercy Health Osteoporosis and Bone Health Services, Cincinnati, OH, ²Univ of California, Los Angeles, CA, ³Rush Medical College, Chicago, IL, ⁴Radius Health, Inc., Waltham, MA, ⁵Clinical Development, Radius Health, Inc., Waltham, MA, ⁶Beth Israel Deaconess Medical Center, Boston, MA, ⁷Brigham and Women's Hospital, Boston, MA
Background/Purpose: Wrist fractures are the most common fracture of the upper extremity and increase subsequent fracture risk in women with postmenopausal osteoporosis. Most wrist fractures…
Abstract Number: 2303 • 2018 ACR/ARHP Annual Meeting
Response Rates for Hip, Femoral Neck, and Lumbar Spine Bone Mineral Density in Patients Treated with Abaloparatide Followed By Alendronate
Chad Deal¹, Bruce Mitlak², Yamei Wang², Lorraine A Fitzpatrick² and Paul D Miller³, ¹Cleveland Clinic, Shaker Heights, OH, ²Radius Health, Inc., Waltham, MA, ³Colorado Center for Bone Research, Lakewood, CO
Background/Purpose: Abaloparatide (ABL) is a selective activator of the PTH1 receptor signaling pathway that stimulates bone formation. In the ACTIVE Phase 3 study, ABL significantly…
Abstract Number: 2309 • 2018 ACR/ARHP Annual Meeting
Implementation of a Primary Prevention, Population-Based Virtual Osteoporosis Clinic Dramatically Increases the Number of Rural Veterans Receiving Osteoporosis Screening and Treatment
Karla L. Miller¹, Shardool Patel², Grant W. Cannon³ and Zachary L. Anderson², ¹Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ²Salt Lake City VA Medical Center, Salt Lake City, UT, ³Division of Rheumatology, Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT
Background/Purpose: The delivery of osteoporosis services is sub-optimal nationally and throughout the Veterans Affairs (VA) healthcare system and particularly poor for rural Veterans. To meet…
Abstract Number: 2312 • 2018 ACR/ARHP Annual Meeting
Spontaneous Vertebral Fractures after Denosumab Discontinuation
Helena Florez¹, Julio Ramírez², Ana Monegal¹, Núria Guañabens¹ and Pilar Peris¹, ¹Department of Rheumatology, Hospital Clinic, University of Barcelona, Barcelona, Spain, ²Rheumatology, Hospital Clínic de Barcelona, Barcelona, Spain
Spontaneous Vertebral Fractures after Denosumab Discontinuation.H. Florez, J. Ramírez, A. Monegal, N. Guañabens, P. Peris. Department of Rheumatology. Hospital Clinic, University of Barcelona. Background/Purpose: Denosumab…
Abstract Number: 2315 • 2018 ACR/ARHP Annual Meeting
Opportunistic Screening for Osteoporosis Using Thoraco-Abdomino-Pelvic Computed Tomography Assessing the Vertebral Density in Rheumatoid Arthritis Patients
Julia Perrier-Cornet¹, Abdou Yacoubou OMOUROU², Marine FAUNY¹, Damien Loeuille³ and Isabelle Chary-Valckenaere⁴, ¹Rheumatology, University Hospital of Nancy, VANDOEUVRE LES NANCY, France, ²Inserm, CIC-1433 Clinical Epidemiology, University Hospital of Nancy, VANDOEUVRE LES NANCY, France, ³Rheumatology, University Hospital of Nancy, NANCY, France, ⁴Rheumatology, CHRU Nancy, Vandoeuvres les Nancy, France
Background/Purpose: Screening for osteoporosis is crucial in rheumatoid arthritis (RA) patients. The aim of this study was to assess the value of thoraco-abdomino-pelvic CT-derived bone…
Abstract Number: 2322 • 2018 ACR/ARHP Annual Meeting
Intervals of Bone Mineral Density Measurement during Treatment for Osteoporosis in Patients with Rheumatoid Arthritis
Seung Yun Lee¹, Seong Ryul Kwon¹, Mie Jin Lim², Kyong-Hee Jung³ and Won Park⁴, ¹Division of Rheumatology, Department of Internal Medicine, Inha University Hospital, Incheon, Korea, Republic of (South), ²Division of Rheumatology, Departments of Internal Medicine, Inha University Hospital, Incheon, Korea, Republic of (South), ³Rheumatology, Inha University Hospital, Incheon, Korea, Republic of (South), ⁴Medicine/Rheumatology, Inha University Hospital, Incheon, Korea, Republic of (South)
Background/Purpose: There is controversy about the intervals of retesting bone mineral density (BMD) in patients treated for osteoporosis. The objective of this study is to…
Abstract Number: 2325 • 2018 ACR/ARHP Annual Meeting
Sex Differences in the Association of Frailty and Bone Mineral Density in Patients with Rheumatoid Arthritis
Katherine D. Wysham¹, Dolores M. Shoback², John B. Imboden Jr.³ and Patricia Katz⁴, ¹University of California, San Francisco, San Francisco, CA, ²Medicine, San Francisco VA Medical Center, University of California, San Francisco, San Francisco, CA, ³Medicine, University of California, San Francisco, San Francisco, CA, ⁴University of California San Francisco, San Francisco, CA
Background/Purpose: Frailty in the general population is associated with poor outcomes including osteoporosis (OP), fracture and death. Frailty occurs at a higher rate in RA…
Abstract Number: 2331 • 2018 ACR/ARHP Annual Meeting
Obesity Might Positively Affect TNF Mediated Bone Metabolism in RA Patients
Mie Jin Lim¹, Won Park², Seong Ryul Kwon³, Kyong-Hee Jung⁴ and Seung Yun Lee³, ¹Division of Rheumatology, Departments of Internal Medicine, Inha University Hospital, Incheon, Korea, Republic of (South), ²Medicine/Rheumatology, Inha University Hospital, Incheon, Korea, Republic of (South), ³Division of Rheumatology, Department of Internal Medicine, Inha University Hospital, Incheon, Korea, Republic of (South), ⁴Rheumatology, Inha University Hospital, Incheon, Korea, Republic of (South)
Background/Purpose: In this study, we tried to find out the effect of obesity on bone metabolism after one year of anti-TNF agent use. Methods: Thirty-two…
Abstract Number: 339 • 2018 ACR/ARHP Annual Meeting
Documenting Bone Health for Veterans with Rheumatoid Arthritis in an Outpatient Academic Clinic
Brittany Ahmed¹, Rabih Nayfe², Akrithi Udupa³, Una E. Makris⁴, Rashmi Arora^1,5 and Swathi Reddy^1,5, ¹UT Southwestern Medical Center, Dallas, TX, ²Department of Medicine, UT Southwestern Medical Center, Dallas, TX, ³Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, ⁴UT Southwestern Medical Center and Dallas VA, Dallas, TX, ⁵Dallas VA Medical Center, Dallas, TX
Background/Purpose: Rheumatoid arthritis (RA) increases the risk of bone density abnormalities such as osteoporosis, predisposing patients to fragility fractures and subsequent morbidity. Osteoporotic fractures incur…
Abstract Number: 2399 • 2018 ACR/ARHP Annual Meeting
Bone Density, Structure and Strength in Canadian Children and Youth with Juvenile Idiopathic Arthritis: The LEAP Study (Linking Exercise, Activity, and Pathophysiology in Canadian Children with Arthritis)
Ciarán M. Duffy¹, Adam Baxter-Jones², Leanne Ward³, Heather Macdonald⁴, Heather McKay⁴, Marta Erlandson², Adam Huber⁵, Susanne Benseler⁶, Michele Gibbon⁷, Jaime Guzman⁸ and Lori Tucker⁸, ¹Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ²University of Saskatchewan, Saskatoon, SK, Canada, ³Department of Paediatrics, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada, ⁴University of British Columbia, Vancouver, BC, Canada, ⁵IWK Health Centre, Halifax, NS, Canada, ⁶Alberta Children's Hospital, Calgary, AB, Canada, ⁷Children's Hospital of Eastern Ontario, Ottawa, ON, Canada, ⁸BC Children's Hospital, Vancouver, BC, Canada
Bone Density, Structure and Strength in Canadian Children and Youth with Juvenile Idiopathic Arthritis: The LEAP Study (Linking Exercise, Activity, and Pathophysiology in Canadian Children…
Abstract Number: 675 • 2018 ACR/ARHP Annual Meeting
Quantitative Ultrasound of the Calcaneus Has a Role to Play in Detecting Low Bone Mineral Density in Axial Spondyloarthropathy Patients
Gillian Fitzgerald^1,2, Tochukwu Anachebe³, Ronan Mullan⁴, David Kane⁵, Kevin McCarroll⁶ and Finbar O' Shea², ¹School of Medicine, Trinity College Dublin, Dublin 2, Ireland, ²Rheumatology, St. James's Hospital, Dublin 8, Ireland, ³Department of Rheumatology, St. James's Hospital, Dublin 8, Ireland, ⁴Department of Rheumatology,, Tallaght Hospital, Dublin, Ireland, ⁵Department of Rheumatology, Tallaght Hospital, Dublin 24, Ireland, ⁶Department of Medicine for the Elderly, St. James's Hospital, Dublin 8, Ireland
Background/Purpose: Axial spondyloarthropathy (axSpA) patients have an increased risk of developing osteoporosis compared to matched controls. Dual energy x-ray absorptiometry (DXA) is the technique of…
Abstract Number: 2575 • 2018 ACR/ARHP Annual Meeting
Long-Term Effects of TNF-Alpha Inhibitors on Bone Mineral Density and the Incidence of Vertebral Fractures in Patients with Ankylosing Spondylitis
Kim Beek¹, Tamara Rusman², Mignon van der Weijden³, Willem F. Lems⁴, Christiaan van Denderen⁵, Michael T. Nurmohamed⁶ and Irene van der Horst-Bruinsma⁷, ¹Rheumatology, Amsterdam Rheumatology immunology Centre/VUmc and Reade, Amsterdam, Netherlands, ²Rheumatology, VU University medical centre, Amsterdam, Netherlands, ³Rheumatology, Groene Hart Ziekenhuis, Gouda, Netherlands, ⁴Department of Rheumatology, VU Medical Center, Amsterdam, Netherlands, ⁵Rheumatology, Jan van Breemen Research Institute | Reade, Amsterdam, Netherlands, ⁶Rheumatology, Amsterdam Rheumatology and immunology Center, VU University Medical Center, Amsterdam, Netherlands, ⁷Rheumatology, VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: Ankylosing Spondylitis (AS) is not only characterized by pathological bone formation leading to ankylosis, but also by bone loss which may lead to vertebral…
Abstract Number: 334 • 2017 ACR/ARHP Annual Meeting
Comparison of Outcomes in Osteoporosis in Patients on Denosumab between Standard and Non-Standard Dosing Intervals
Nouman A. Syed, Mohammed Wiqar, Douglas Einstadter and Marina N. Magrey, Case Western Reserve University at MetroHealth Medical Center, Cleveland, OH
Background/Purpose: Denosumab (Dmab) is an antiresorptive agent with an approximate half-life of 26 days and according to the prescribing information the recommended dose is 60…

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