Abstracts tagged "bone biology"

Abstract Number: 37 • 2014 ACR/ARHP Annual Meeting
Regulation of Osteoclast and T Cell Differentiation By DC-STAMP and TRAF3
Yahui Grace Chiu¹, Jinbo Li², Dongge Li¹, Brendan Boyce² and Christopher T. Ritchlin³, ¹Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, ²Pathology, University of Rochester, Rochester, NY, ³Allergy Immunology & Rheumatology, University of Rochester Medical Center, Rochester, NY
Background/Purpose DC-STAMP (Dendritic Cell-Specific Transmembrane Protein) is a 7-pass transmembrane protein essential for cell-to-cell fusion during OC differentiation. We have previously shown that DC-STAMP is…
Abstract Number: 19 • 2014 ACR/ARHP Annual Meeting
Adenosine Receptors Stimulate Bone Regeneration
Aranzazu Mediero¹, Tuere Wilder² and Bruce N. Cronstein³, ¹Medicine, Division of Translational Medicine, NYU School of Medicine, New York, NY, ²Medicine, division of Translational Medicine, NYU School of Medicine, New York, NY, ³NYU School of Medicine, Division of Rheumatology, New York, NY
Background/Purpose Such orthopedic procedures as spinal fusion and repair of bone defects due to trauma, infection or metastatic disease, require formation of new bone. Adenosine,…
Abstract Number: 29 • 2014 ACR/ARHP Annual Meeting
Impaired Bone Healing in Patients Suffering from Rheumatoid Arthritis – Anti-Inflammatory Therapy As Confounder
Annemarie Lang¹, Sarah Fuegener², Paula Hoff², Anastasia Rakow³, Manuela Jakstadt⁴, Timo Gaber⁴, Gerd Burmester², Carsten Perka³ and Frank Buttgereit⁵, ¹Berlin-Brandenburg School of Regenerative Therapies (BSRT), Berlin, Germany, ²Department of Rheumatology and Clinical Immunology, Charité University Medicine, Berlin, Germany, ³Center for Musculoskeletal Surgery, Orthopedic Department, Charité University Medicine, Berlin, Germany, ⁴Berlin-Brandenburg Center of Regenerative Therapies (BCRT), Berlin, Germany, ⁵Charité University Hospital, Berlin, Germany
Background/Purpose Anti-inflammatory treatment of rheumatoid arthritis (RA) with glucocorticoids (GC) and/or non-steroidal anti-inflammatory drugs (NSAIDs) is supposed to negatively influence bone metabolism and healing. It…

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