Abstracts tagged "body mass"

Abstract Number: 515 • 2016 ACR/ARHP Annual Meeting
The Association of Body Mass Index with the Severity of Magnetic Resonance Imaging-Detected Inflammation at Presentation; Opposite Effects in Early Rheumatoid Arthritis Compared to Other Arthritides and an Asymptomatic Population
L. Mangnus¹, W.P. Nieuwenhuis², H.W. van Steenbergen², T.W.J. Huizinga³, M. Reijnierse⁴ and A.H.M. van der Helm-van Mil², ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Leiden University Medical Center, Leiden, Netherlands, ³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Radiology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: An increased body mass index (BMI) has been associated with slightly increased inflammatory markers in the population. Within rheumatoid arthritis (RA) a high BMI…
Abstract Number: 548 • 2016 ACR/ARHP Annual Meeting
Body Mass Index Is Positively Correlated with Diverse Disease Activity Measures in Longstanding Rheumatoid Arthritis
Craig Wiesenhutter, Coeur d'Alene Arthritis Clinic, Coeur D Alene, ID; University of Washington School of Family Medicine, Seattle, ID
Background/Purpose: Obesity is a common problem with patients who have rheumatoid arthritis (RA). Adipose tissue has been shown to produce cytokines that are proinflammatory. The…
Abstract Number: 1640 • 2016 ACR/ARHP Annual Meeting
Effect of BMI on Baricitinib Efficacy: Pooled Analysis from Two Phase 3 Rheumatoid Arthritis Clinical Trials
Cristiano A.F Zerbini¹, David Muram², Vipin K. Arora², Jahangir Alam² and Jeffrey R. Curtis³, ¹Centro Paulista de Investigação Clinica, São Paulo, Brazil, ²Eli Lilly and Company, Indianapolis, IN, ³Division Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose : The efficacy of some rheumatoid arthritis (RA) therapies is reduced among patients with high BMI. This analysis assessed the effects of baseline BMI…
Abstract Number: 1944 • 2016 ACR/ARHP Annual Meeting
Disease Activity, Glucocorticoid Exposure, and Rituximab Determine Body Composition Changes during Induction Treatment of ANCA-Associated Vasculitis
Zachary Wallace¹, Eli Miloslavsky², Sebastian H. Unizony³, Na Lu⁴, Gary S. Hoffman⁵, Cees G.M. Kallenberg⁶, Carol A. Langford⁷, Peter A. Merkel⁸, Paul A. Monach⁹, Philip Seo¹⁰, Robert F. Spiera¹¹, Eugene William St.Clair¹², Paul Bruntetta¹³, Matthew Cascino¹⁴, Hyon K. Choi¹⁵ and John H. Stone³, ¹Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA, ²Division of Rheumatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ³Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA, ⁴Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁵Rheumatology, Cleveland Clinic, Cleveland, OH, ⁶Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ⁷Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, ⁸Division of Rheumatology, Univ of Pennsylvania; Perelman School of Med, Philadelphia, PA, ⁹Rheumatology, Boston University School of Medicine, Boston, MA, ¹⁰Medicine, Johns Hopkins University, Baltimore, MD, ¹¹Hospital for Special Surgery, Cornell, New York, NY, ¹²Rheumatology and Immunology, Duke University, Durham, NC, ¹³Genentech, Inc., South San Francisco, CA, ¹⁴University of California-San Francisco, San Francisco, CA, ¹⁵Rheumatology, Allergy and Immunology, Massachusetts General Hospital and Harvard Medical School, Boston, MA
Background/Purpose: ANCA-associated vasculitis (AAV) treatment includes high dose glucocorticoids (GCs), which are associated with increased body-mass index (BMI), a complication abhorred by patients and associated…
Abstract Number: 2026 • 2016 ACR/ARHP Annual Meeting
Are Adult Trajectories of Weight over a Lifetime Linked to Foot Problems Years Later?
Alyssa B. Dufour¹, Elena Losina², Hylton B. Menz³, Michael P. Lavalley⁴ and Marian T. Hannan⁵, ¹Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School & Beth Israel Deaconess Medical Center, Boston, MA, ²Orthopaedics, Brigham & Women's Hospital, Boston, MA, ³Musculoskeletal Research Centre, La Trobe University, Bundoora, VIC, Australia, ⁴Biostatistics, Boston University School of Public Health, Boston, MA, ⁵Institute for Aging Research, Hebrew SL & Harvard Med School, Boston, MA
Background/Purpose: Obesity and foot problems are common in older adults and associated with many negative health outcomes. Better understanding of the consequences of patterns of…
Abstract Number: 2051 • 2016 ACR/ARHP Annual Meeting
Risk Factors for Cardiovascular Disease Predate the Onset of Symptoms of Rheumatoid Arthritis
Heidi Kokkonen¹, Lisbeth Ärlestig² and Solbritt Rantapää-Dahlqvist^3,4, ¹Public Health and Clinical Medicine/ Rheumatology, Umeå University, Umeå, Sweden, ²Public Health and Clinical Medicine/Rheumatology, Umeå University, Umeå, Sweden, ³Department for Public Health and Clinical Medicine/ Rheumatology, Umeå University, Umeå, Sweden, ⁴Rheumatology, Umeå University, Umeå, Sweden
Background/Purpose: Patients with rheumatoid arthritis (RA) are at increased risk of developing cardiovascular (CV) comorbidity compared with the general population. Contradictory results concerning CV disease…
Abstract Number: 2494 • 2016 ACR/ARHP Annual Meeting
The Effect of Body Mass on DAS28 Response in Patients with Rheumatoid Arthritis Treated with Abatacept
J Fransen¹, L Tweehuysen², A den Broeder³, R Postema⁴, E Alemao⁵ and F van den Hoogen⁶, ¹Department of Rheumatolgy, Radboud UMC, Nijmegen, Netherlands, ²Sint Maartenskliniek Nijmegen, Nijmegen, Netherlands, ³Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, ⁴Bristol-Myers Squibb, Uxbridge, United Kingdom, ⁵Bristol-Myers Squibb, Princeton, NJ, ⁶Rheumatology, Radboud UMC, Nijmegen, Netherlands
Background/Purpose: Abatacept is an effective biologic agent indicated for the treatment of RA.1 Recent studies have indicated that obesity and being overweight could reduce the…
Abstract Number: 2544 • 2016 ACR/ARHP Annual Meeting
Glucocorticoid Treatment for 12 Weeks in Early Rheumatoid Arthritis Is Related to an Increase in BMI
Samina A. Turk¹, Linda A. Rasch², Sylvia de Boer¹, Mike T. Nurmohamed^1,3, Willem F. Lems^2,4 and Dirkjan van Schaardenburg^1,5, ¹Rheumatology, Amsterdam Rheumatology and immunology Center, location Reade, Amsterdam, Netherlands, Amsterdam, Netherlands, ²Rheumatology, Amsterdam Rheumatology and immunology Center, location VU University Medical Center, Amsterdam, Netherlands, Amsterdam, Netherlands, ³Rheumatology, Amsterdam Rheumatology and immunology Center, Location VU University Medical Center, Amsterdam, Netherlands, Amsterdam, Netherlands, ⁴Amsterdam Rheumatology and immunology Center, location Reade, Amsterdam, Netherlands, Amsterdam, Netherlands, ⁵Rheumatology, Amsterdam Rheumatology and immunology Center, location Academic Medical Center, Amsterdam, Netherlands, Amsterdam, Netherlands
Background/Purpose: After the diagnosis of rheumatoid arthritis (RA), glucocorticoids (GCs) are a common initial treatment in addition to methotrexate (MTX)(1). However, many patients are afraid…
Abstract Number: 2756 • 2016 ACR/ARHP Annual Meeting
Gender Differences in Body Composition with Dual-Energy X-Ray Absorptiometry in TNF-α Blocker Naive Ankylosing Spondylitis Patients
Sebastián Ibáñez^1,2, Ingrid M. Visman³, Christiaan van Denderen³, Willem F. Lems^4,5, M. Nurmohamed^4,6 and Irene van der Horst - Bruinsma⁴, ¹Reumatología, Clínica Alemana de Santiago, Santiago, Chile, ²Reumatología, Hospital Padre Hurtado, Santiago, Chile, ³Rheumatology, Amsterdam Rheumatology and immunology Center, location Reade, Amsterdam, Netherlands, ⁴Rheumatology, Amsterdam Rheumatology and immunology Center, VU University medical center, Amsterdam, Netherlands, ⁵Rheumatology, Amsterdam Rheumatology and immunology Center, location Reade, Amsterdam, New Caledonia, ⁶Amsterdam Rheumatology and immunology Center, location Reade, Amsterdam, Netherlands
Background/Purpose: Data on body composition (BC) in Ankylosing Spondylitis (AS) are sparse and controversial. Female AS patients have less response to TNF-α blockers and a…
Abstract Number: 3047 • 2016 ACR/ARHP Annual Meeting
Diabetes and BMI Modify the Association Between Painful Hip OA and All-Cause Mortality
Rebecca Cleveland¹, Todd A. Schwartz², Jordan B. Renner³, Leigh F. Callahan¹ and Joanne M. Jordan¹, ¹Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ²Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, ³Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC
Background/Purpose: Individuals with specific comorbid conditions have increased risk of having hip osteoarthritis (OA). Some of these conditions are also associated with increased risk of…
Abstract Number: 256 • 2015 ACR/ARHP Annual Meeting
The Predominant Attack Type and Associated Clinical-Laboratory Conditions in Patients with Familial Mediterranean Fever
Mustafa Cakar¹, Muharrem Akhan², Muhammet Cinar¹ and Sedat Yılmaz¹, ¹Rheumatology, Gulhane Medical Faculty, Ankara, Turkey, ²Internal Medicine, Gulhane Medical Faculty, Ankara, Turkey
Background/Purpose: Familial Mediterranean Fever (FMF) is an autoinflammatory disease characterized by recurrent attacks of fever and serositis. Abdominal pain is the most frequent symptom of…
Abstract Number: 1564 • 2015 ACR/ARHP Annual Meeting
Initiation of Disease Modifying Therapies and Subsequent Weight Change in Rheumatoid Arthritis
Joshua Baker¹, Brian Sauer², Kaleb Michaud³, Grant W. Cannon⁴, Said Ibrahim⁵, Liron Caplan⁶, Lisa A. Davis⁶, Amy C. Cannella⁷ and Ted R. Mikuls⁸, ¹Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, ²IDEAS Center and Division of Epidemiology, HSR&D SLC VA Medical Center and University of Utah, Salt Lake City, UT, ³Rheumatology & Immunology, University of Nebraska Medical Center and National Data Base for Rheumatic Diseases, Omaha, NE, ⁴Internal Medicine, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, UT, ⁵Medicine, University of Pennsylvania, Philadelphia, PA, ⁶Div of Rheumatology, Univ of CO Denver School of Med, Aurora, CO, ⁷Section of Rheumatology, University of Nebraska Med Ctr, Omaha, NE, ⁸University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Low body mass index (BMI) predicts adverse outcomes in rheumatoid arthritis (RA), in part due to weight loss among patients with severe disease and…
Abstract Number: 1582 • 2015 ACR/ARHP Annual Meeting
Joint Damage Associated with Loss of Body Mass in Rheumatoid Arthritis
Jose Felix Restrepo¹, Inmaculada del Rincon², Daniel Battafarano³ and Agustin Escalante⁴, ¹Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX, ²Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, ³Rheumatology, San Antonio Military Medical Center, JBSA - Ft Sam Houston, TX, ⁴Dept. of Medicine-Rheumatology, University of Texas Health Science Center at San Antonio, San Antonio, TX
Background/Purpose: Body mass index (BMI) is a predictor of long-term outcome in rheumatoid arthritis and has been associated with joint damage. Our objective was to examine…
Abstract Number: 3182 • 2015 ACR/ARHP Annual Meeting
High Body Mass Index Negatively Impacts Time to Achieving Sustained Remission in Early Rheumatoid Arthritis: Results from a Multicenter Early Arthritis Cohort Study
Elizabeth Schulman¹, Kathleen Andersen², Meng Zhang³, Susan M. Goodman⁴, Daming Lin⁵, Gilles Boire⁶, Boulos Haraoui⁷, Carol Hitchon⁸, Shahin Jamal⁹, Edward C. Keystone¹⁰, Janet E. Pope¹¹, Diane Tin¹², Carter Thorne¹³, VP Bykerk² and CATCH Investigators, ¹Rheumatology, Hospital for Special Surgey, New York, NY, ²Hospital for Special Surgery, New York, NY, ³Epidemiology and Biostatistics, Hospital for Special Surgery, New York, NY, ⁴Rheumatology, Hospital for Special Surgery, New York, NY, ⁵Rheumatology, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ⁶Department of Medicine/Division of Rheumatology, University of Sherbrooke, Sherbrooke, QC, Canada, ⁷Institut de Rhumatologie de Montréal, Montréal, QC, Canada, ⁸University of Manitoba, Winnipeg, MB, Canada, ⁹Vancouver Coastal Health, Vancouver, BC, Canada, ¹⁰Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, ¹¹University of Western Ontario, London, ON, Canada, ¹²The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ¹³Southlake Regional Health Centre, Newmarket, ON, Canada
Background/Purpose: High BMI has been associated with worse disease severity and lower rates of sustained remission (susREM) in early rheumatoid arthritis (ERA). In this study,…
Abstract Number: 3248 • 2015 ACR/ARHP Annual Meeting
Which Factors Explain Multi-Site Pain Caused By Obesity: A 5-Year Follow-up Study in Older Adults?
Feng Pan¹, Laura Laslett², Russell Thomson², Tania Winzenberg³, Flavia Cicuttini⁴, Changhai Ding⁵ and Graeme Jones⁵, ¹Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart,7000, Australia, ²Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ³Menzies Institute for Medical Research, University of Tasmania, Hobart,7000, Australia, ⁴Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia, ⁵Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia
Background/Purpose: Joint pain is common in older adults; typically multiple joints are involved. Obesity is an important risk factor in pathogenesis of multi-site joint pain…

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