Abstracts tagged "Biostatistics"

Abstract Number: 1357 • ACR Convergence 2025
Measuring Rheumatoid Arthritis Outcomes Using Machine Learning Imputed Disease Activity Scores
Jue Hou¹, Feiqing Huang², Gregory McDermott³, Jun Wen⁴, Mary Jeffway³, Ying Qi⁵, Yunqing Han³, Tianrun Cai⁶, Florence Bourgeois⁴, Katherine Liao⁷ and Tianxi Cai², ¹University of Minnesota, Minneapolis, MN, ²Harvard T.H. Chan School of Public Health, Boston, ³Brigham and Women's Hospital, Boston, ⁴Harvard Medical School, Boston, ⁵Brigham and Women’s Hospital, Boston, ⁶Brigham and Women's Hospital, Boston, MA, ⁷Division of Rheumatology, Inflammation, and Immunity, Brigham and Women’s Hospital, Boston, MA, USA, Boston, MA
Background/Purpose: Validated rheumatoid arthritis (RA) disease activity measures such as the Disease Activity Score-28 (DAS28) are used in clinical trials but not universally recorded in…
Abstract Number: 1151 • ACR Convergence 2025
A Comparison of Patients with Cardiac Sarcoidosis vs. Other Systemic Manifestations of Sarcoidosis: A Retrospective Cohort Study
Chelsea Guan¹, Dana Nachawati¹, Amir Daneshvar¹, Keri Ann Pfeil¹, Elleson Harper¹, Lindsay Frumker², Meghan Gump¹, Vicky Nahra³ and Omer Pamuk⁴, ¹University Hospitals Cleveland Medical Center/Case Western Reserve University, Cleveland, OH, ²University hospitals Cleveland medical center, Highland Heights, OH, ³University Hospitals Cleveland Medical Center/Case Western Reserve University, Cleveland Heights, OH, ⁴University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH
Background/Purpose: Sarcoidosis is a systemic autoimmune disease with multiorgan involvement. In this study, we analyzed the differences in characteristics in patients with sarcoid myocarditis (cardiac…
Abstract Number: 0566 • ACR Convergence 2025
Predictor Risk Factors For Developing Difficult-to-Treat Psoriatic Arthritis in Patients Initiating a First bDMARD: a Binational Study
Astrid Goudot¹, Raphaël Hurtubise², Eugénie Robin³, Laurine Cadart⁴, Raghav Ramachandran⁵, Federica Re⁵, Tristan Pascart⁶, Cécile Philippoteaux⁷, René-Marc Flipo⁷, Laura Coates⁸ and Jean-Guillaume Letarouilly¹, ¹Université de Lille, CHU Lille, Service de rhumatologie, Lille, France, Lille, Nord-Pas-de-Calais, France, ²Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Oxford, United Kingdom, ³CH Valenciennes, Service de rhumatologie, Valenciennes, France, Valenciennes, France, ⁴Service de biostatistiques, CHU Lille, Lille, France, Lille, France, ⁵Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, UK, Oxford, United Kingdom, ⁶GHICL, Hôpital Saint-Philibert, Service de rhumatologie, Lomme, France, Lomme, France, ⁷Université de Lille, CHU Lille, Service de rhumatologie, Lille, France, Lille, France, ⁸Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, England, United Kingdom
Background/Purpose: Risk factors to identify patients who will develop a difficult-to-treat (D2T) psoriatic arthritis (PsA) are still lacking when initiating a first bDMARD. There are…
Abstract Number: 0415 • ACR Convergence 2025
The Impact of Social Vulnerability Index Scores in Pediatric Uveitis
Minal Aundhia¹, Pankaj Rajdeo², Michael Wagner¹, Alexandra Duell¹, Megan Quinlan-Waters³, Virginia Miraldi Utz¹ and Sheila Angeles-Han⁴, ¹Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Cincinnati Children's Hospital Medical Center, Cincinnati, ³Cincinnati Children's Hospital Medical Center, CCHMC, ⁴Cincinnati Children's Hospital, Cincinnati, OH
Background/Purpose: Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children with uveitis as the most common extra-articular manifestation. Uveitis can lead to…
Abstract Number: 2572 • ACR Convergence 2025
Multi-Modal Machine Learning Prediction and Phenotyping of Systemic Lupus Erythematosus Using Longitudinal EHR and Genomic Data from the All of Us Program
Hunter Sporn¹, Roshni Parulekar-Martins¹, Haopeng Wang¹, Xinran Yu¹, Jeong Yee², Youngmin Kim³, Jing Cui⁴ and Karen H. Costenbader⁵, ¹Massachusetts Institute of Technology, Boston, ²Sungkyunkwan University, Suwon, MA, South Korea, ³Brigham and Women's Hospital, Boston, MA, ⁴Brigham and Women's Hospital/ Harvard Medical School, Boston, ⁵Harvard Medical School and Brigham and Women's Hospital, Boston, MA
Background/Purpose: Timely diagnosis and clinically meaningful stratification of systemic lupus erythematosus (SLE) remain major unmet needs. Existing risk models rely on limited genetic or lifestyle…
Abstract Number: 0174 • ACR Convergence 2025
Genetic and Environmental Risk Factors and Incident Rheumatoid Arthritis
Xuesen Zhao¹, Puran Nepa², Hui Yu³, Laura Daniel², Vivian Kawai⁴, Michael Stein⁵, Yan Guo³ and Cecilia Chung³, ¹University of Miami, Miami, FL, ²University of Miami, Research Service, Miami VA Healthcare System, Miami, FL, ³University of Miami, Miami, ⁴University of Alabama at Birmingham, Birmingham, AL, ⁵Vanderbilt University Medical Center, Nashville, TN
Background/Purpose: While some studies have linked air pollution to risk for rheumatoid arthritis (RA), U.S.-based studies utilizing nationwide exposure data remain limited and often exclude…
Abstract Number: 2389 • ACR Convergence 2025
A Comparison of Patients with Older Onset vs. Younger Onset SLE: A Retrospective Cohort Study
Chelsea Guan¹, Milad Heydari-Kamjani², Keri Ann Pfeil¹, Elleson Harper¹, Lindsay Frumker³, Meghan Gump¹ and Omer Pamuk², ¹University Hospitals Cleveland Medical Center/Case Western Reserve University, Cleveland, OH, ²University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH, ³University hospitals Cleveland medical center, Highland Heights, OH
Background/Purpose: SLE is a systemic autoimmune disease that can present at different ages and with various multiorgan complications. In this study, we aimed to analyze…
Abstract Number: 2354 • ACR Convergence 2025
ChatGPT or SPSS? A comparison between AI-based and Traditional Statistical Analysis of Longitudinal Inflammatory Marker Data in Spondyloarthritis
José Miguel Sequí-Sabater¹, Pablo Beltrán Martin-Lorente², Sonia Pastor Navarro³, Maria del Carmen Lopez Gonzalez⁴, Maria Sanchez-Wonenburger⁵, DESAMPARADOS CASADO POVEDA³ and Anna Martínez Cristóbal⁶, ¹La Ribera University Hospital, Rheumatology Department, Gandía, Spain, ²Universidad Católica de Valencia "San Vicente Mártir", Valencia, Comunidad Valenciana, Spain, ³La Ribera University Hospital, Rheumatology Department, Valencia, Comunidad Valenciana, Spain, ⁴La Ribera University Hospital, Rheumatology Department, Cullera, Comunidad Valenciana, Spain, ⁵Hospital Universitario de La Ribera, València, Comunidad Valenciana, Spain, ⁶La Ribera University Hospital, Rheumatology Department, Alzira, Comunidad Valenciana, Spain

Background/Purpose: While traditional analysis relies on statistical software such as SPSS, emerging tools like ChatGPT introduce the possibility of performing statistical tests, interpreting results, and…
Abstract Number: 2340 • ACR Convergence 2025
Lighten the Load: Artificial Intelligence Reveals Body Mass Index Outranks Treatment in One-Year Psoriatic Arthritis Outcomes—Findings from the SPEED Trial
Alexander Garaiman¹, Sophia Massa¹, Elnaz Saeedi², Nicola Gullick³, William Tillett⁴, Raphaël Hurtubise¹, jean-guillaume letarouilly⁵ and Laura Coates⁶, ¹Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Oxford, United Kingdom, ²Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK., Oxford, ³Rheumatology Department, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK, Coventry, United Kingdom, ⁴Department of Life Sciences, Centre for Therapeutic Innovation, University of Bath, Bath, United Kingdom, ⁵Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK, Oxford, United Kingdom, ⁶Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, England, United Kingdom
Background/Purpose: Personalizing care in early psoriatic arthritis (PsA) is challenging. We set out to identify predictors of one-year response on the PASDAS using AI-based methods…
Abstract Number: 2241 • ACR Convergence 2025
RADAR: A Deep Learning Pipeline for Automated Scoring of Joint Damage in Rheumatoid Arthritis Radiographs
Hugo PENSEC¹, Alain SARAUX², florent garrigues³, yoann le duault¹, sandrine jousse⁴, baptiste quere⁴, nathan foulquier⁵, Valerie Devauchelle⁶ and ikram brahim⁷, ¹CHRU Brest, Brest, France, ²CHU Brest, Brest, France, ³CHU de BREST, Brest, Bretagne, France, ⁴LBAI, UMR¹²²⁷, University of Brest, CHU Brest, Brest, France, Brest, France, ⁵LBAI, UMR¹²²⁷, Univ Brest, Inserm, Brest, France, Brest, France, ⁶UBO, Brest, France, ⁷CHRU, LBAI, UMR¹²²⁷, Univ Brest, Inserm, LaTIM, UMR ¹¹⁰¹, Brest, France, Brest, France
Background/Purpose: Rheumatoid arthritis (RA) is a persistent inflammatory disorder inducing joint space narrowing and erosion at both hands and feet. Reading of X-ray images remains…
Abstract Number: 1917 • ACR Convergence 2025
Characterizing the Frequency and Timing of Changes in Patient-Reported Social Risk Factors among Rheumatology Outpatients
Daphne Lew¹, Lauren Seidler², Patrice Odom³, Amy McQueen³, Jessica Williams⁴, Seth Eisen⁵ and Alfred Kim⁴, ¹Washington University in St. Louis School of Medicine, Saint Louis, MO, ²Washington University School of Medicine, Saint Louis, ³Washington University School of Medicine, Saint Louis, MO, ⁴Washington University School of Medicine, St. Louis, MO, ⁵Washington University School of Medicine, St Louis, MO
Background/Purpose: Social risk factors (SRFs) are associated with health outcomes, and patients with chronic conditions often report disproportionately higher rates of SRFs, complicating their disease…
Abstract Number: 1908 • ACR Convergence 2025
Clinical and Imaging Features of Haemochromatosis Arthropathy – a Systematic Literature Review and Meta- Analysis
Svenja Engelhardt¹, Sabine Buroh², Guido Schwarzer³, Andreas Kerschbaumer⁴, Axel Braner⁵, Mathilde Herber⁶, Pedro Machado⁷, Patrick Kiely⁸ and Stephanie Finzel⁹, ¹University of Freiburg, Freiburg im Breisgau, Germany, ²Library of the Medical Center - University of Freiburg, Faculty of Medicine, Library of the Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany, Freiburg, Germany, ³University of Freiburg, Freiburg, Germany, Institute of Medical Biometry and Statistics, Faculty of Medicine and Medical Center - University of Freiburg, Freiburg, Germany, Freiburg, Germany, Freiburg, Germany, ⁴Stanford University / Medical University of Vienna, Stanford, CA, ⁵MVZ Aschaffenburg, Aschaffenburg, Germany, Frankfurt, Germany, ⁶Strasbourg Centre University, Strasbourg, France, Department of Internal Medicine, Strasbourg, France, Strasbourg, France, ⁷Department of Rheumatology, University College London, and Department of Rheumatology, Northwick Park Hospital, London North West University Healthcare NHS Trust, Centre for Rheumatology & Department of Neuromuscular Diseases, University College London, London, United Kingdom, ⁸St George's University Hospitals NHS Foundation Trust, London, United Kingdom, ⁹Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
Background/Purpose: Haemochromatosis arthropathy (HA) has been little researched to date. Arthropathy frequently is amongst thefirst clinical manifestations of haemochromatosis, but might be overlooked or misdiagnosed…
Abstract Number: 1647 • ACR Convergence 2025
Clinical Phenotypes of Participants with Radiographic Osteoarthritis Attaining Patient Acceptable Symptom State in the Multicenter Osteoarthritis Study
Sarah Tilley¹, Michael LaValley², Brooke McGinley³, Cora Lewis⁴, James Torner⁵, David Felson³ and Tuhina Neogi⁶, ¹Boston University School of Medicine, Somerville, MA, ²Boston University School of Public Health, Arlington, MA, ³Boston University, Boston, MA, ⁴The University of Alabama at Birmingham, Birmingham, AL, ⁵University of Iowa, Iowa City, IA, ⁶Boston University School of Medicine, Boston, MA
Background/Purpose: Osteoarthritis (OA) is a leading cause of pain and disability in older adults marked by progressive joint degeneration. Symptom trajectories vary: some experience persistent…
Abstract Number: 1643 • ACR Convergence 2025
Optimizing Analyses of Chair Stand Test Outcome Data in the Multicenter Osteoarthritis Study: Exploration of Approaches to Handling Missing and/or Skewed Data with Performance-based Function Measures
Michael LaValley¹, Vanessa Vu², Maggie Westerland², Yuqing Li², Cora Lewis³, Laura Frey Law⁴, David Felson² and Tuhina Neogi⁵, ¹Boston University School of Public Health, Arlington, MA, ²Boston University, Boston, MA, ³The University of Alabama at Birmingham, Birmingham, AL, ⁴Department of Physical Therapy and Rehabilitation Science, Carver College of Medicine, University of Iowa, Iowa City, IA, ⁵Boston University School of Medicine, Boston, MA
Background/Purpose: Maintaining physical function is crucially important in aging. Lower body function is often measured with the chair stand test (CST), also known as the…
Abstract Number: 1573 • ACR Convergence 2025
Health-related quality of life over 15 years in systemic sclerosis: impact of sex and survival
Katherine van der Wouden¹, Georgy Gomon², Rachel Knevel², Michel Tsang-A-Sjoe³, Alexandre Voskuijl³ and Jeska de Vries-Bouwstra², ¹Leiden University Medical Center and Amsterdam University Medical Center, Leiden, Zuid-Holland, Netherlands, ²Leiden University Medical Center, Leiden, Netherlands, ³Amsterdam University Medical Center, Amsterdam, Netherlands
Background/Purpose: Patients with systemic sclerosis (SSc) face an uncertain long‑term outlook; understanding how their health‑related quality of life (HRQoL) changes over time can help them…

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