ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2025
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • 2020-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstracts tagged "Biomarkers"

  • Abstract Number: 854 • 2017 ACR/ARHP Annual Meeting

    Predictive Modeling of Mortality in Polymyositis/Dermatomyositis Patients with Interstitial Lung Disease Based on Combination of Serum Myositis-Specific Autoantibodies and Conventional Biomarkers

    Takahisa Gono1, Kenichi Masui2, Yasushi Kawaguchi3, Kei Ikeda4, Atsushi Kawakami5, Maasa Tamura6, Yoshinori Tanino7, Takahiro Nunokawa8, Yuko Kaneko9, Shinji Sato10, Katsuaki Asakawa11, Naoshi Nishina9 and Masataka Kuwana1, 1Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 2Department of Anesthesiology, National Defense Medical College School of Medicine, Tokorozawa, Japan, 3Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, 4Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan, 5Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki City, Japan, 6Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama, Japan, 7Department of Pulmonary Medicine, Fukushima Medical University School of Medicine, Fukushima, Japan, 8Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan, 9Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, 10Division of Rheumatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan, 11Division of Respiratory Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan

    Background/Purpose: Interstitial lung disease (ILD) is one of the leading causes of mortality in patients with polymyositis or dermatomyositis (PM/DM). Since clinical courses and outcomes…
  • Abstract Number: 1389 • 2017 ACR/ARHP Annual Meeting

    Serum Progranulin Antibodies (PGRN-abs) in Rheumatoid Arthritis Patients Being Negative for RF-IgM and ACCP-IgG

    Gunter Assmann1, Silke Zinke2, Moritz Gerling3, Natalie Fadle3, Klaus Dieter Preuss3, Michael Pfreundschuh3 and Lorenz Thurner3, 1Medicine I, University Medical School of Saarland, 66424, Germany, 2Rheumapraxis, Rheumatology Center Berlin - Lichtenberg, Berlin, Germany, 3Medicine I, Jose Carreras Center, University of Saarland, Homburg, Germany

    Background/Purpose: Until recently, most research on progranulin (PGRN) had been focused on its role in neurogenerative diseases as frontotemporal dementia. After the detection of elevated…
  • Abstract Number: 1977 • 2017 ACR/ARHP Annual Meeting

    Elevated Levels of Eotaxin-2 in Serum of Fibromyalgia Patients

    Victoria Furer1, Eyal Hazan2, Adi Mor3, Michal Segal3, Avi Katav3, Valerie Aloush4, Ori Elkayam4, Jacob George3,5 and Jacob N. Ablin6,7, 1Rheumatology, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel, 2Internal Medicine D, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 3ChemomAb Ltd. Israel, Tel Aviv, Israel, 4Rheumatology, Tel Aviv Sourasky Medical Center and the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, 5Heart Institute, Kaplan Medical Center, Rehovot, Israel, 6Internal Medicine H, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 7Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel

    Background/Purpose: Fibromyalgia is a widespread chronic pain syndrome (FMS) the pathogenesis of which remains incompletely understood. FMS patients demonstrate an altered profile of chemokines relative…
  • Abstract Number: 2816 • 2017 ACR/ARHP Annual Meeting

    Prediction of Connective Tissue Disease in an at-Risk Cohort Using a Novel Interferon Stimulated Gene Expression Score

    Md Yuzaiful Md Yusof1,2, Yasser M El-Sherbiny1,3, Antonios Psarras1, Elizabeth M.A. Hensor1,4, Adewonuola Alase1, Alaa Mohamed1, Miriam Wittmann1,4, Paul Emery1,4 and Edward M Vital1,4, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 2NIHR Leeds Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 3Clinical Pathology dept., School of Medicine, Mansoura University, Mansoura, Egypt, 4NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Prediction of connective tissue disease in an at-risk cohort using a novel interferon stimulated gene expression scoreBackground/Purpose: A period of ANA positivity and other immune…
  • Abstract Number: 75 • 2017 ACR/ARHP Annual Meeting

    Factors Associated with TNF Receptor 2 Levels Above the Measurable Range in Rheumatoid Arthritis

    Michelle Frits1, Gary Bradwin2, Nancy A. Shadick1, Christine Iannaccone3, Michael Weinblatt1, Nader Rifai2 and Katherine P. Liao4, 1Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 2Laboratory Medicine, Childrens Hospital Boston, Boston, MA, 3Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 4Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: Tumor necrosis factor-alpha (TNFa) is involved in the pathogenesis of RA and is increasingly being studied as a biomarker of cardiovascular disease (CVD).  While…
  • Abstract Number: 668 • 2017 ACR/ARHP Annual Meeting

    Is Uric Acid Level a Predictor of Long-Term Renal Outcome in Lupus Nephritis?

    Michelle Lopes1, Samara Gavinier2, Elaine Leon2, Vilma Viana2, Eduardo Ferreira Borba1 and Eloisa Bonfa3, 1Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 2Rheumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR, São Paulo, Brazil, 3Rheumatology Divison, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Hyperuricemia has been reported to be associated with chronic kidney disease (CKD) in several clinical conditions, and recent studies also observed an association between…
  • Abstract Number: 867 • 2017 ACR/ARHP Annual Meeting

    Highly Sensitive Cardiac Troponin-I in Peripheral Blood Predicts Cardiovascular Events in Patients with Rheumatoid Arthritis

    George Karpouzas1, Joel Estis2, Long Pham3, John Todd2 and Matthew Budoff4, 1Division of Rheumatology, Harbor-UCLA Medical Center, Torrance, CA, 2Singulex, Alameda, California, Alameda, CA, 3Rheumatology, Harbor-UCLA Medical Center, Torrance, CA, 4Cardiology, Harbor-UCLA Medical Center, Torrance, CA

    Background/Purpose: Cardiac troponins (cTn) are specific biomarkers of myocardial injury; their measurement with highly-sensitive assays and at subthreshold levels for myocardial infarction (MI) diagnosis, predicts…
  • Abstract Number: 1399 • 2017 ACR/ARHP Annual Meeting

    Tissues Are Differently Modulated By Tocilizumab and Methotrexate; Assessment of Connective Tissue Metabolites in the Ambition Study

    Anne C. Bay-Jensen1, Anne Sofie Siebuhr1, Christian S. Thudium2 and Morten Asser Karsdal1, 1Rheumatology, Nordic Bioscience, Herlev, Denmark, 2Biomarkers and Research, Nordic Bioscience, Herlev, Denmark

    Background/Purpose: The response to any treatment in rheumatoid arthritis (RA) is assessed by symptomatic changes, such as swollen joint count and DAS28. However, such assessments…
  • Abstract Number: 2075 • 2017 ACR/ARHP Annual Meeting

    The Effect of Uric Acid Lowering Treatment on the Microbiome in Gout Patients

    Hye Won Kim1, Eun-Jeong Yoon2, Seok Hoon Jeong2 and Min-Chan Park1, 1Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine,Gangnam Severance Hospital, Seoul, Korea, Republic of (South), 2Department of Laboratory Medicine, Severance Hospital, Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea, Republic of (South)

    Background/Purpose: Accumulating evidence indicates that gut microbiota interact with gout but it is still unknown how the uric acid lowering treatment (ULT) affects to the…
  • Abstract Number: 2858 • 2017 ACR/ARHP Annual Meeting

    Validation of Biomarkers to Predict Flare in Polyarticular JIA upon Stopping Anti-TNF Therapy

    Daniel J Lovell1, Sarah Ringold2 and P. Scott Eastman3, 1PRCSG, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2Seattle Children's Hospital, Seattle, WA, 3Senior Director, New Product Development, Crescendo Bioscience, South San Francisco, CA

    Background/Purpose: More than 40% of children with polyarticular forms of Juvenile Idiopathic Arthritis (JIA) experience clinical inactive disease on medication (CR). No clinical variable or…
  • Abstract Number: 78 • 2017 ACR/ARHP Annual Meeting

    IL-37 Is Associated with Increased Atherogenesis in Patients with Rheumatoid Arthritis

    Barbora Sumova1,2, Tereza Lennerova1,2, Lucie Andres Cerezo1, Hana Hulejova1, Romana Jandova1, Karel Pavelka1,2, Jiri Vencovsky1,2 and Ladislav Senolt1,2, 1Institute of Rheumatology, Prague, Czech Republic, Prague, Czech Republic, 2Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic

    Background/Purpose: Interleukin-37 (IL-37) is one of few anti-inflammatory cytokines belonging to the IL-1 cytokine family. It is mainly produced by immune cells of innate immunity…
  • Abstract Number: 674 • 2017 ACR/ARHP Annual Meeting

    Identification of IRAK4-Dependent Gene Signature As a Biomarker Candidate for IRAK4 Small-Molecule Inhibitor in Systemic Lupus Erythematosus

    A. Francesca Setiadi1, Kate Senger1, Jason Hackney2, Neta Zuckerman1, Swathi Sujatha-Bhaskar1, George Francis1, Marian Bryan1, Hans Brightbill1, Ali A. Zarrin1 and Michael J. Townsend1, 1Genentech, South San Francisco, CA, 2Bioinformatics and Computational Biology, Genentech, South San Francisco, CA

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is a heterogeneous disease. Interleukin-1 receptor-associated kinase 4 (IRAK4) activity is predicted to affect multiple pathogenic pathways in SLE1. We…
  • Abstract Number: 940 • 2017 ACR/ARHP Annual Meeting

    IL1RN Variation Is Associated with Systemic Juvenile Idiopathic Arthritis and Predicts Non-Response to Anakinra Treatment

    Emily Shuldiner1, Victoria Arthur1, Anne Hinks2, Patricia Woo3, Wendy Thomson2, Elaine F. Remmers4 and Michael J. Ombrello1, 1Translational Genetics and Genomics Unit, NIAMS, NIH, Bethesda, MD, 2Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Manchester Academic Health Sciences Centre, The University of Manchester, Manchester, United Kingdom, 3University College London, London, United Kingdom, 4Genetics and Genomics Branch, NIH, NIAMS, Bethesda, MD

    Background/Purpose: Systemic juvenile idiopathic arthritis (sJIA) is a childhood inflammatory disease whose pathophysiology is poorly understood. sJIA is phenotypically heterogeneous with variable manifestations and responses…
  • Abstract Number: 1416 • 2017 ACR/ARHP Annual Meeting

    Higher Expression of Type 1 Interferon in Synovitis of Patient with Undifferentiated Arthritis before They Met Rheumatoid Arthritis Criteria Compared to Established Rheumatoid Arthritis.  a Retrospective Study with 14 Years of Follow-up

    Andrea Cuervo1, Raquel Celis2, Julio Ramírez3, Alicia Usategui4, Regina Faré5, M. Victoria Hernández6, Virginia Ruiz-Esquide3, Jose Inciarte-Mundo7, Raimon Sanmarti8, Jose L. Pablos9 and Juan D. Cañete7, 1Arthritis Unit. Rheumatology Dpt, Arthritis Unit, Rheumatology Dpt, Hospital Clinic of Barcelona and IDIBAPS, Barcelona, Spain, 2Arthritis Unit, Rheumatology Department, Arthritis Unit, Rheumatology Dpt, Hospital Clinic of Barcelona and IDIBAPS, Barcelona, Spain, 3Rheumatology Service, Hospital Clínic de Barcelona, Barcelona, Spain, 4Grupo de Enfermedades Inflamatorias y Autoinmunes, Instituto de Investigación Hospital 12 de Octubre (i+12), Madrid, Spain, 5Instituto de Investigación Hospital 12 de Octubre (i+12), Madrid, Spain, 6Hospital Clinic. Barcelona. Spain, Barcelona, Spain, 7Rheumatology Department, Arthritis Unit, Rheumatology Dpt, Hospital Clinic of Barcelona, Barcelona, Spain, 8Arthritis Unit, Rheumatology Dpt, Hospital Clinic of Barcelona, Barcelona, Spain, 9Servicio de Reumatología, Hospital 12 de Octubre, Madrid, Spain

    Background/Purpose: Undifferentiated Arthritis (UA) is defined as an inflammatory oligo/poly arthritis that does not fulfil criteria for a definitive diagnosis.Delay in diagnosis and treatment leads…
  • Abstract Number: 2176 • 2017 ACR/ARHP Annual Meeting

    Clusterin Is Upregulated in Muscle Tissue and Serum in Idiopathic Inflammatory Myopathies and Is Associated with Clinical Disease Activity

    Tereza Lennerova1,2, Lucia Vernerova1, Martin Klein1, Veronika Hruskova1,3, Lucie Andres Cerezo1, Barbora Sumova1,2, Michal Tomcik1,2, Sabina Oreska1,2, Herman F Mann1,2, Josef Zamecnik4, Karel Pavelka1,2, Jiri Vencovsky1,2 and Ladislav Senolt1,2, 1Institute of Rheumatology, Prague, Czech Republic, Prague, Czech Republic, 2Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, 3Faculty of Science, Charles University, Prague, Czech Republic, Prague, Czech Republic, 4Department of Pathology and Molecular Medicine, 2nd Medical School and University Hospital Motol, Charles University, Prague, Czech Republic, Prague, Czech Republic

    Background/Purpose: Clusterin (also known as apolipoprotein J) is a molecular chaperone that participates in a number of biological processes, such as inflammation and apoptosis. Recent…
  • « Previous Page
  • 1
  • …
  • 74
  • 75
  • 76
  • 77
  • 78
  • …
  • 109
  • Next Page »
Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

Embargo Policy

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2026 American College of Rheumatology