ACR Meeting Abstracts

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Abstracts tagged "biologic response modifiers"

  • Abstract Number: 636 • 2017 ACR/ARHP Annual Meeting

    Effect of Adding MTX to TNF Inhibitors on Joint Severity Indices and Skin Scores in Psoriatic Arthritis: A Post-Hoc Meta-Analysis of Randomized, Controlled Trials

    Rochelle Castillo1, Khushboo Sheth2 and Santhanam Lakshminarayanan3, 1University of Connecticut, Farmington, CT, 2Rheumatology, Stanford University, Palo Alto, CA, 3Division of Rheumatology, University of Connecticut Health Center, Farmington, CT

    Background/Purpose: Co-medication of MTX with TNF inhibitors (TNFi) has proven superior to TNFi monotherapy in improving clinical outcomes in patients with RA. Whether this holds…
  • Abstract Number: 2906 • 2017 ACR/ARHP Annual Meeting

    Use of Disease-Modifying Antirheumatic Drugs, Biologic Response Modifiers and Corticosteroids, and Subsequent Risk of Coccidioidomycosis Infection Among Medicare Beneficiaries

    Dominick Sudano1, C. Kent Kwoh2, Lili Zhou3, Erin L. Ashbeck4 and Wei-Hsuan Lo-Ciganic5, 1University of Arizona Arthritis Center, University of Arizona, Tucson, AZ, 2University of Arizona, Tucson, AZ, 3Department of Pharmacy, Practice and Science, University of Arizona, College of Pharmacy, Tucson, AZ, 4The University of Arizona Arthritis Center, Tucson, AZ, 5Department of Pharmacy, Practice and Science, College of Pharmacy, University of Arizona, Associate professor, TUCSON, AZ

    Background/Purpose: Coccidioidomycosis (Cocci) is a fungal infection endemic to seven states in the US. Biologic response modifiers (BRMs) have been shown to increase the risk…
  • Abstract Number: 649 • 2016 ACR/ARHP Annual Meeting

    Clinical Evaluation Usefulness of Standardized Protocol Strategies of Dose Reduction in Patients with Rheumatoid Arthritis in Clinical Remission Treated with Biologic Therapies. the Optibio Study

    Carmen Bejerano1, Natividad Oreiro1, Carlos Fernandez-Lopez2, Jose A Pinto-Tasende1, Antonio Atanes1, Bruno De Aspe1, Genaro Graña Gil1, Mercedes Freire1, Manuel Acasuso3, Sonia Pertega4, Francisco J. de Toro1 and Francisco J Blanco1, 1Rheumatology Division, INIBIC-Complejo Hospitalario Universitario A Coruña (CHUAC), A Coruna, Spain, 2Rheumatology Division, INIBIC-Complejo Hospitalario Universitario A Coruña (CHUAC), La Coruña, Spain, 3Centro de Salud San Jose, XAP Coruna, A Coruna, Spain, 4Epidemiology Unit, INIBIC - Complejo Hospitalario Universitario A Coruña, A Coruña, Spain

    Background/Purpose: The OPTIBIO study is a clinical trial whose primary endpoint is to evaluate the proportion of patients that after one year are maintained in…
  • Abstract Number: 1350 • 2016 ACR/ARHP Annual Meeting

    Asymptomatic Coccidioidomycosis in Patients with Rheumatic Disease: 8 Years of Experience

    Usman Ajaz1, Jeffrey R. Lisse2, Neil M. Ampel3 and Dominick Sudano4, 1Department of Medicine, University of Arizona, Tucson, AZ, 2Arizona Arthritis Center, University of Arizona, Tucson, AZ, 3Department of Infectious Disease, Southern AZ VA Medical Center, Tucson, AZ, 4Department of Rheumatology, University of Arizona, Tucson, AZ

    Background/Purpose: Coccidioidomycosis (valley fever) is an endemic fungal infection that typically causes a self-limited pulmonary illness in the Southwestern United States,. Immunosuppressed patients are at…
  • Abstract Number: 2482 • 2016 ACR/ARHP Annual Meeting

    Long Term Drug Survival of Adalimumab and Etanercept Treatment for Rheumatoid Arthritis with and without Methotrexate

    I.M Visman1, MJ l'Ami2, Gertjan Wolbink3 and Mike T. Nurmohamed4,5, 1Amsterdam Rheumatology and Immunology Center, Reade, Amsterdam, Netherlands, 2Amsterdam Rheumatology and immunology Center, Reade, Amsterdam, Netherlands, 3Rheumatology, Amsterdam Rheumatology and immunology Center, location Reade, Amsterdam, Netherlands, 4Rheumatology, Reade, Amsterdam Rheumatology and immunology Center, Amsterdam, Netherlands, 5Rheumatology, Amsterdam Rheumatology and immunology Center, VU University medical center, Amsterdam, Netherlands

    Background/Purpose: Tumor necrosis factor alpha (TNF-α) inhibitors are effective, safe and widely used treatment for rheumatoid arthritis (RA). The therapy is often started in combination…
  • Abstract Number: 2641 • 2016 ACR/ARHP Annual Meeting

    Safety of Synthetic and Biological Dmards: Slr Informing the Update of the EULAR Recommendations for the Management of RA

    Sofia Ramiro1, Alexandre Sepriano1, Katerina Chatzidionysiou2, Jackie L. Nam3, Josef Smolen4, Désirée van der Heijde5, Maxime Dougados6, Ronald van Vollenhoven7, Johannes WJ Bijlsma8, GR Burmester9, Marieke Scholte-Voshaar10 and RBM Landewé11, 1Leiden University Medical Center, Leiden, Netherlands, 2Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden, 3Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 4Internal Medicine III, Div. of Rheumatology, Medical University of Vienna, Vienna, Austria, 5Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 6Paris Descartes University, Paris, France, 7Amsterdam Rheumatology Center, Amsterdam, Netherlands, 8Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 9Charité – University Medicine Berlin, Berlin, Germany, 10EULAR Standing Committee of People with Arthritis/Rheumatism in Europe, Zurich, Switzerland, 11Amsterdam Medical Center, Amsterdam, Netherlands

    Background/Purpose: As part of the update of the EULAR recommendations for the management of RA, we performed a systematic literature review to assess the safety…
  • Abstract Number: 548 • 2015 ACR/ARHP Annual Meeting

    Comparison of Dose Escalation and Co-Therapy Intensification Between Patients with Rheumatoid Arthritis Initiating Biologic Treatment with Etanercept, Adalimumab and Infliximab

    J Carter Thorne1, Gilles Boire2, Andrew Chow3, Kirsten Garces4, Fang Liu5, Melanie Poulin-Costello6, Valery Walker5 and Boulos Haraoui7, 1Southlake Regional Health Centre, Newmarket, ON, Canada, 2Department of Medicine/Division of Rheumatology, Université de Sherbrooke, Sherbrooke, QC, Canada, 3Credit Valley Rheumatology, Mississauga, ON, Canada, 4Amgen Canada Inc, Mississauga, ON, Canada, 5Optum, Burlington, ON, Canada, 6Amgen Canada Inc., Mississauga, ON, Canada, 7Institut de rhumatologie de Montréal, Montreal, QC, Canada

    Background/Purpose: The individual response to anti-TNFs etanercept (ETA), infliximab (INF) and adalimumab (ADA) in rheumatoid arthritis (RA) may vary. Options for managing inadequate response include…
  • Abstract Number: 601 • 2015 ACR/ARHP Annual Meeting

    Step-Down Strategy of Spacing TNF-Blockers Injections for Established Rheumatoid Arthritis in Remission: A within Randomized Control Trial Based Cost-Utility Analysis

    Antoine Vanier1, Florence Tubach2, Toni Alfaiate3, Xavier Mariette4 and Bruno Fautrel5, 1Biostatistics, Public Health and Medical Informatics, AP-HP Pitié-Salpêtrière Hospital / Pierre and Marie Curie University Paris 6, Paris, France, 2Epidemiology and Clinical Research, AP-HP Bichat Hospital / University of Paris-Diderot / INSERM CIC-EC 1425, Paris, France, 3Epidemiology and Clinical Research, AP-HP Bichat Hospital / INSERM CIC-EC 1425, Paris, France, 4Université Paris-Sud, AP-HP, Hôpitaux Universitaires Paris-Sud, Paris, France, 5Rheumatology, AP-HP Pitié-Salpêtrière Hospital / Pierre and Marie Curie University Paris 6 GRC-08 (EEMOIS), Paris, France

    Background/Purpose: Once remission is achieved for patients with rheumatoid arthritis (RA), treatment down-titration should be attempted, for safety issues or economic reasons. One of the…
  • Abstract Number: 2205 • 2014 ACR/ARHP Annual Meeting

    Management of Asymptomatic Coccidioidomycosis in Patients with Rheumatic Disease

    Dominick Sudano1, Varun Bhalla2, Neil M. Ampel3,4 and Jeffrey R. Lisse5, 1Rheumatology, University of Arizona, Tucson, AZ, 2University of Arizona, Tucson, AZ, 3Infectious Disease, University of Arizona, Tucson, AZ, 4Infectious Disease, Southern Arizona Veteran's Affairs Medical Center, Tucson, AZ, 5Department of Rheumatology, University of Arizona, Tucson, AZ

    Background/Purpose: In the Southwestern United States, coccidioidomycosis (valley fever) is an endemic fungal infection which typically causes a self-limited pulmonary illness. Immunosuppressed patients, including those…
  • Abstract Number: 2387 • 2013 ACR/ARHP Annual Meeting

    Change of serum Amyloid a predict The Effect Of Biological Treatment In Rheumatoid Arthritis Patient

    Chisa Okura1, Yukio Yonemoto2, Koichi Okamura1, Tetsuya Kaneko3, Tsutomu Kobayashi1 and Kenji Takagishi1, 1Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan, 2Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, Maebashi, Japan, 3Department of Orthopaedic Surgery, Inoue Hospital, Takasaki, Gunma, Japan

    Background/Purpose: The C-reactive protein (CRP) level and the erythrocyte sedimentation rate (ESR) are common markers of inflammation in patients with rheumatoid arthritis (RA). The serum…
  • Abstract Number: 382 • 2013 ACR/ARHP Annual Meeting

    Effect Of Biologic Disease Modifiers On Cardiovascular Risk Of Patients With Rheumatoid Arthritis – 2 Years Prospective Cohort Study

    Majed M. Khraishi1 and Rana Aslanov2, 1Nexus Clinical Research, St John's, NF, Canada, 2Clinical Epidemiology Department, Faculty of Medicine, Memorial University of Newfoundland, St.John's, NF, Canada

    Background/Purpose: People with RA have a higher risk for developing cardiovascular diseases than the general population. The pathogenic mechanisms in RA appear to be complex…
  • Abstract Number: 2172 • 2012 ACR/ARHP Annual Meeting

    An Update of Management of Coccidioidomycosis in Patients On Biologic Response Modifiers and Disease-Modifying Antirheumatic Drugs

    Susan Knowles1, Dominick Sudano1, Sara Taroumian2, Neil M. Ampel3, John Galgiani4, Jeffrey R. Lisse1 and Susan E. Hoover5, 1Department of Rheumatology, University of Arizona, Tucson, AZ, 2Department of Rheumatology, University of California, Los Angeles, Los Angeles, CA, 3Infectious Disease, University of Arizona, Tucson, AZ, 4Valley Fever Center for Excellence, Tucson, AZ, 5Infectious Diseases, University of Arizona, Tucson, AZ

    Background/Purpose: Coccidioidomycosis (valley fever) is an endemic fungal infection in the Southwestern United States which typically causes a self-limited pulmonary illness. Patients with rheumatic disease…
  • Abstract Number: 1142 • 2012 ACR/ARHP Annual Meeting

    Efficacy of Biologic Agents in Juvenile Idiopathic Arthritis: A Systematic Review Using Indirect Comparisons

    Janneke Anink1, Marieke H. Otten1, Sandra Spronk2 and Lisette W.A. Van Suijlekom-Smit1, 1Pediatric Rheumatology, Erasmus MC Sophia Children's Hospital, Rotterdam, Netherlands, 2Department of Epidemiology and Radiology, Erasmus MC, Rotterdam, Netherlands

    Background/Purpose: During the last decade the availability of biologic agents for the treatment of juvenile idiopathic arthritis (JIA) increased substantially. Because direct head-to-head trials comparing…
  • Abstract Number: 2155 • 2012 ACR/ARHP Annual Meeting

    The Annualized Progression of Radiologic Damage in Placebo Arms of Rheumatoid Arthritis Trials Is Much Lower Than the Mean Annual Progression Since Disease Onset

    Jean-Marie Berthelot and Celine Cozic, Rheumatology Unit, Nantes University Hospital, Nantes, France

    Background/Purpose : A previous meta-analysis by Graudal and Jürgens (Arthritis Rheum. 2010;62:2852–63) challenged the belief that biologics better protect rheumatoid arthritis (RA) from joint destruction…
  • Abstract Number: 1145 • 2012 ACR/ARHP Annual Meeting

    Use of Non-Etanercept Biologics in Children with Juvenile Idiopathic Arthritis: Results From the Biologics for Children with Rheumatic Diseases Study

    Lianne Kearsley-Fleet1, Eileen Baildam2, Michael Beresford3, Rebecca Davies4, Helen E. Foster5, Katy Mowbray1, Taunton R. Southwood6, Wendy Thomson1 and Kimme L. Hyrich7, 1Arthritis Research UK Epidemiology Unit, Manchester Academic Health Science Centre, Manchester, United Kingdom, 2Paediatric Rheumatology, Alder Hey Children's Foundation NHS Trust, Liverpool, United Kingdom, 3University of Liverpool, Institute of Translational Medicine (Child Health), Alder Hey Children's Foundation NHS Trust, Liverpool, United Kingdom, 4Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, United Kingdom, 5Institute Cellular Medicine, Musculoskeletal Research Group, Newcastle upon Tyne, United Kingdom, 6Institute of Child Health, University of Birmingham and Birmingham Children's Hospital, Birmingham, United Kingdom, 7Centre for Musculoskeletal Research, University of Manchester, Manchester, United Kingdom

    Background/Purpose: The management of juvenile idiopathic arthritis (JIA) has been revolutionised by the introduction of biologic therapy, although the majority remain unlicensed for children. Until…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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