Abstracts tagged "Behcet’s syndrome"

Abstract Number: 3045 • 2015 ACR/ARHP Annual Meeting
Anti-Alpha-Enolase Antibodies in Behçet’s Disease: A Marker of Articular Disease Activity?
Leandro L. Prado, Celio R. Gonçalves, Vilma S. T. Viana, Eloisa Bonfá and Carla G.S. Saad, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Diagnosis of Behçet´s disease (BD) is challenging because is based solely on clinical features. Articular involvement in this disease may mimic other diagnosis such…
Abstract Number: 204 • 2015 ACR/ARHP Annual Meeting
Histone Methylation Profiling in Peripheral White Blood Cells As a Candidate Biomarker for Behcet’s Disease
Yoshimi Aizaki^1,2, Yasuto Araki^1,2, Kojiro Sato¹, Yuji Akiyama¹ and Toshihide Mimura^1,2, ¹Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Saitama, Japan, ²Project Research Division, Research Center for Genomic Medicine, Saitama Medical University, Saitama, Japan
Background/Purpose: Behcet’s disease (BD) is a chronic recurrent, multisystem inflammatory disorder. The phenotypic characteristics include oral aphtha, genital ulcers, uveitis and skin lesions. No specific…
Abstract Number: 3046 • 2015 ACR/ARHP Annual Meeting
Venous Disease-Specific Quality-of-Life Is Impaired in Patients with Vascular Behcet’s Disease
Fatma Alibaz-Oner¹, Belgin Aldag², Mustafa Aldag³, Ali Ugur Unal⁴, Tayfur Toptas⁵, Tülin Ergun⁶ and Haner Direskeneli⁴, ¹Department Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, ²Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, ³Dr.Siyami Ersek Cardiovascular Surgery Hospital,, Istanbul, Turkey, ⁴Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, ⁵Hematology, Marmara University, Istanbul, Turkey, ⁶Dermatology, Marmara University Faculty of Medicine, Dermatology, Istanbul, Turkey
Background/Purpose: Vascular involvement is seen in up to 40% of the patients with Behcet's disease (BD), with lower extremity deep vein thrombosis (DVT) as the most…
Abstract Number: 1247 • 2015 ACR/ARHP Annual Meeting
Methylation Analysis of HLA-B Locus in Familial Behçet Syndrome
Eda Tahir Turanli¹, Pelinsu Koprulu², Serdal Ugurlu³, Hasan Yazici⁴ and Emire Seyahi³, ¹Molecular Biology and Genetics Department, Istanbul Technical University, Istanbul, Turkey, ²Molecular Biology Genetics and Biotechnology Program, Istanbul Technical University, Istanbul, Turkey, ³Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Turkey, Istanbul, Turkey, ⁴Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey
Background/Purpose: Our focus has been on the potential role of the epigenetic processes, mainly of the methylation, on the development of Beh�et syndrome (BS) using…
Abstract Number: 3049 • 2015 ACR/ARHP Annual Meeting
Cognitive Dysfunction in Chronic Progressive Neuro-Behçet’s Disease: Comparative Study of the Brainstem and Hippocampus Region Using Brain Magnetic Resonance Imaging
Hirotoshi Kikuchi¹, Kurumi Asako¹, Maki Takayama¹, Shoko Iga¹, Yoshitaka Kimura¹, Hajime Kono¹ and Shunsei Hirohata², ¹Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan, ²Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Kanagawa, Japan
Background/Purpose: Central nervous system involvement is one of the most serious complications in Behçet's disease (BD). This condition is referred to as neuro-Behçet's disease (NB)…
Abstract Number: 1370 • 2015 ACR/ARHP Annual Meeting
CD40/CD40L Pathway Is Associated with Increased Oxidative Burst and Neutrophil Extracellular Traps Release in Behcet´s Disease
Sandro F. Perazzio^1,2, Paulo Vitor Soeiro Pereira³, Alexandre W.S. Souza⁴, Antonio Condino-Neto³ and Luis Eduardo C. Andrade⁵, ¹Rheumatology Division, Universidade Federal de São Paulo, Sao Paulo, Brazil, ²Fleury Medicine and Health, Sao Paulo, Brazil, ³Immunology, ICB IV - Universidade de São Paulo, São Paulo, Brazil, ⁴Rheumatology Division, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, ⁵Immunology Division, Fleury Medicine and Health, São Paulo, Brazil
Background/Purpose: Previous studies suggested that unknown plasma factors increase oxidative burst in Behçet’s disease (BD), but little is known about neutrophil extracellular traps (NET) formation.…
Abstract Number: 3052 • 2015 ACR/ARHP Annual Meeting
Budd-Chiari Syndrome in Behçet’s Disease:a Retrospective Multicenter Study
Lutfi Akyol¹, Bahtiyar Toz², Ozun BayndÄ±r³, Orhan Zengin⁴, Dondu Uskudar Cansu⁵, Murat Yigit⁶, Gozde Yildirim Cetin⁷, Ahmet Omma⁸, Abdulsamet Erden⁹, Orhan Kucuksahin¹⁰, Senol Kobak¹¹, Osman Cure¹, Ali Ugur Unal¹², Ayten Yazici¹³, Metin Ozgen¹, Ali Sahin¹⁴, Emel Gonullu¹⁵, Suleyman Serdar Koca¹⁶, Burak Erer², Ahmet Gul¹⁷, Kenan Aksu³, Gokhan Keser¹⁸, Ahmet Mesut Onat⁴, Bunyamin Kisacik⁴, Timucin Kasifoglu⁵, Ayse Cefle¹⁹, Umut Kalyoncu⁹ and Mehmet Sayarlioglu¹, ¹Department of Internal Medicine Division of Rheumatology, Ondokuz Mayıs University, Faculty of Medicine, Samsun, Turkey, ²Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ³Ä°nternal Medicine Division of Rheumatology, Ege University Medical Faculty, Izmir, Turkey, ⁴Ä°nternal Medicine Division of Rheumatology, Gaziantep University, Faculty of Medicine, Gaziantep, Turkey, ⁵Ä°nternal Medicine Division of Rheumatology, Osmangazi University, Faculty of Medicine, Eskisehir, Turkey, ⁶Ä°nternal Medicine Division of Rheumatology, Pamukkale University, Faculty of Medicine, Denizli, Turkey, ⁷Rheumatology, Kahramanmaras University School of Medicine, Kahramanmaras, Turkey, ⁸Department of Internal Medicine, Rheumatology Division, Ankara Numune Hospital, Ankara, Turkey, ⁹Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, ¹⁰Rheumatology, Yildirim Beyazit University School of Medicine, Ankara, Turkey, ¹¹Rheumatology, Sifa University, Izmir, Turkey, ¹²Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, ¹³Rheumatology, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey, ¹⁴Department of Rheumatology, Cumhuriyet University Faculty of Medicine, Sivas, Turkey, ¹⁵Rheumatology, Osmangazi University, Faculty of Medicine, Eskisehir, Turkey, ¹⁶İnternal Medicine Division of Rheumatology, Firat University, Faculty of Medicine, Elazig, Turkey, ¹⁷Department of Internal Medicine, Rheumatology Division, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ¹⁸Rheumatology, Ege University Medical Faculty, Izmir, Turkey, ¹⁹Ä°nternal Medicine Division of Rheumatology, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey
Background/Purpose: Budd-Chiari syndrome (BCS), or hepatic venous outflow obstruction, is a rare and serious complication of Behçet's disease (BD). The aim of this study was…
Abstract Number: 1389 • 2015 ACR/ARHP Annual Meeting
A Meta-Analysis of the Prevalence of the Ocular Manifestations in All Inflammatory Rheumatic Diseases
Jacqueline Hayworth¹ and Janet E. Pope², ¹Medicine, University of Western Ontario and U of Toronto, Toronto, ON, Canada, ²University of Western Ontario, London, ON, Canada
Background/Purpose: Many inflammatory rheumatic diseases (IRD) are associated with ocular involvement. The prevalence of these complications is not fully known. This meta-analysis was performed to…
Abstract Number: 3054 • 2015 ACR/ARHP Annual Meeting
Takayasu’s Arteritis Associated with Behçet’s Syndrome: A Case Series of 8 Patients
Sinem Nihal Esatoglu¹, Emire Seyahi², Serdal Ugurlu², Gulen Hatemi², Melike Melikoglu², Vedat Hamuryudan³ and Sebahattin Yurdakul¹, ¹Rheumatology, Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Turkey, Istanbul, Turkey, ²Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Turkey, Istanbul, Turkey, ³Rheumatology, Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey
Background/Purpose: Takayasu's arteritis (TA) and Behçet's syndrome (BS) are both systemic vasculitis of an unknown etiology, each with unique involvement pattern. TA affects aorta and…
Abstract Number: 3034 • 2015 ACR/ARHP Annual Meeting
A Comparative Metabolomic Evaluation of Behcet’s Disease with Arthritis and Seronegative Arthritis Using Synovial Fluid
Joong Kyong Ahn¹, Sooah Kim², Jungyeon Kim², Jiwon Hwang³, Hyungjin Kim⁴, Hyemin Jeong⁵, Yeong Hee Eun⁶, Chan Hong Jeon⁷, Jaejoon Lee⁵, Eun-Mi Koh⁵, Kyoung Heon Kim² and Hoon-Suk Cha⁸, ¹Department of Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea, ²Department of Biotechnology, Korea University Graduate School, Seoul, South Korea, ³Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea, ⁴Department of medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, ⁵Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, ⁶Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, ⁷Department of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, South Korea, ⁸Division of Rheumatology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
Background/Purpose: Behcet’s disease (BD) is a chronic, complex systemic vasculitis of unknown etiology characterized by orogenital ulcers, uveitis, and arthritis. Arthritis and arthralgias in BD…
Abstract Number: 3224 • 2015 ACR/ARHP Annual Meeting
Salivary IL-1 Alpha and IL-1 Beta Levels Are Associated with Oral Mucosal Activity in Behcet’s Disease
Nilufer Alpay Kanitez¹, Bahtiyar Toz¹, Feyza Berktas¹, Sertan Ergun², Meltem Koray², Nuray Gurel Polat³, Burak Erer¹ and Ahmet Gül¹, ¹Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ²Department of Oral Medicine, Istanbul University, Faculty of Dentistry, Istanbul, Turkey, ³Department of Microbiology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey
Background/Purpose: Recurrent oral aphthous ulcers are the common manifestation of the Behçet's disease (BD), and they are indistinguishable from ulcers of recurrent aphthous stomatitis (RAS).…
Abstract Number: 3035 • 2015 ACR/ARHP Annual Meeting
HLA B51 and Possible Associated Autoimmune Disorders Other Than Behcets Disease: A Retrospective Cohort Study
Luis Salayandia¹, Wilmer Sibbitt Jr.¹, Arthur Bankhurst², Roderick Fields³, Gladys Cook⁴, Konstantin Konstantinov⁵ and Suzanne Emil¹, ¹Rheumatology, University of New Mexico, Albuquerque, NM, ²Rheum/ MSC 105550, University of NM Med Ctr, Albuquerque, NM, ³Rheumatology, University of New Mexico, Albquerque, NM, ⁴Rheumatology, UNM, Albuquerque, NM, ⁵1 University Of New Mexico, University of New Mexico, Albuquerque, NM
Background/Purpose: The diagnostic utility of HLA B51 in association with Behcet’s disease has been clearly identified; however the correlation of HLA B51 with other autoimmune…
Abstract Number: 3225 • 2015 ACR/ARHP Annual Meeting
Whole Exome Sequencing Identifies Rare Protein-Coding Variants in Behcet’s Disease
Mikhail Ognenovski¹, Paul Renauer¹, Ina Koetter², Joerg C. Henes³, Bruno Casali⁴, Carlo Salvarani⁵, Haner Direskeneli⁶, Kenneth M. Kaufman⁷ and Amr H. Sawalha¹, ¹Division of Rheumatology, University of Michigan, Ann Arbor, MI, ²Internal Medicine IV Rheumatology, Asklepios Klinik Altona, Hamburg, Germany, ³Department of Internal Medicine II, Rheumatology Division, University Hospital Tuebingen, Tuebingen, Germany, ⁴Divisione di Biologia Molecolare, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy, ⁵Rheumatology, Arcispedale S.Maria Nuova, Reggio Emilia, Italy, ⁶Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, ⁷Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: Behcet’s disease (BD) is a systemic inflammatory disease characterized by recurrent oral and genital ulcers, skin lesions, uveitis, and other organ complications such as…
Abstract Number: 3036 • 2015 ACR/ARHP Annual Meeting
The Association Between Behcet’s Disease, Myelodysplastic Syndrome and Trisomy 8
Won-Seok Lee¹, Yun Jung Choi², Myong-Joo Hong³, Chang-Hoon Lee⁴, Myeung Su Lee⁵, Young Sun Suh⁶, Sang-Il Lee⁷, Yong Gon Cho⁸ and Wan-Hee Yoo⁹, ¹Division of Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine of Chonbuk National University Hospital-Chonbuk National University, jeonju, South Korea, ²Division of Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine of Chonbuk National University Hospital-Chonbuk National University, JeonJu, South Korea, ³Internal Medicine, Presbyterian Medical center, Jeonju, South Korea, ⁴Department of Internal Medicine, School of Medicine, Wonkwang University, Iksan, Chonbuk, South Korea, ⁵Internal Medicine, School of Medicine, Wonkwang University, Iksan, Chonbuk, South Korea, ⁶Division of Rheumatology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, South Korea, ⁷Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, South Korea, ⁸Department of Laboratory medicine, Chonbuk National University Medical School and Hospital, Jeonju, South Korea, ⁹Division of Rhuematology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine of Chonbuk National University Hospital-Chonbuk National University, Jeonju, South Korea
Background/Purpose: Behcet’s disease (BD) is a systemic vasculitis, whereas myelodysplastic syndrome (MDS) is a heterogeneous group of clonal hematologic disorders characterized by ineffective hematopoiesis. Some…
Abstract Number: 3226 • 2015 ACR/ARHP Annual Meeting
Increased Serum Levels of IgG Antibodies Against to Alpha-Enolase Are Associated with Severity of Oral Ulcers in Patients with Behcet’s Disease
Shin Eui Kang¹, Sang Jin Lee^2,3, Jin Kyun Park^2,4, Joo Youn Lee², Eun Young Lee³, Eun Bong Lee³ and Yeong Wook Song^3,5, ¹Department of Molecular Medicine and Biopharmaceutical Sciences, BK 21 plus Graduate School of Convergence Science and Technology, and College of Medicine or College of Parmarcy, Seoul National University, Seoul, South Korea, ²Department of Molecular Medicine and Biopharmaceutical Sciences, BK21 plus Graduate School of Convergence Science and Technology, and College of Medicine or College of Pharmacy, Seoul National University, Seoul, South Korea, ³Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea, ⁴Department of Molecular Medicine and Biopharmaceutical Sciences Graduate School of Convergence Science and Technology, and College of Medicine or College of Pharmacy Seoul National University, Seoul, South Korea, ⁵Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology and College of Medicine Seoul National University, Seoul, South Korea
Background/Purpose: Behcet's Disease (BD) is a chronic inflammatory disease characterized by recurrent oral and genital ulcers, skin lesions, uveitis, and arthritis. Although the etiology of…

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