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Abstracts tagged "Behcet’s syndrome"

  • Abstract Number: 3045 • 2015 ACR/ARHP Annual Meeting

    Anti-Alpha-Enolase Antibodies in Behçet’s Disease: A Marker of Articular Disease Activity?

    Leandro L. Prado, Celio R. Gonçalves, Vilma S. T. Viana, Eloisa Bonfá and Carla G.S. Saad, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Diagnosis of Behçet´s disease (BD) is challenging because is based solely on clinical features. Articular involvement in this disease may mimic other diagnosis such…
  • Abstract Number: 204 • 2015 ACR/ARHP Annual Meeting

    Histone Methylation Profiling in Peripheral White Blood Cells As a Candidate Biomarker for Behcet’s Disease

    Yoshimi Aizaki1,2, Yasuto Araki1,2, Kojiro Sato1, Yuji Akiyama1 and Toshihide Mimura1,2, 1Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Saitama, Japan, 2Project Research Division, Research Center for Genomic Medicine, Saitama Medical University, Saitama, Japan

    Background/Purpose: Behcet’s disease (BD) is a chronic recurrent, multisystem inflammatory disorder. The phenotypic characteristics include oral aphtha, genital ulcers, uveitis and skin lesions. No specific…
  • Abstract Number: 3046 • 2015 ACR/ARHP Annual Meeting

    Venous Disease-Specific Quality-of-Life Is Impaired in Patients with Vascular Behcet’s Disease

    Fatma Alibaz-Oner1, Belgin Aldag2, Mustafa Aldag3, Ali Ugur Unal4, Tayfur Toptas5, Tülin Ergun6 and Haner Direskeneli4, 1Department Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, 2Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, 3Dr.Siyami Ersek Cardiovascular Surgery Hospital,, Istanbul, Turkey, 4Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, 5Hematology, Marmara University, Istanbul, Turkey, 6Dermatology, Marmara University Faculty of Medicine, Dermatology, Istanbul, Turkey

    Background/Purpose: Vascular involvement is seen in up to 40% of the patients with Behcet's disease (BD), with lower extremity deep vein thrombosis (DVT) as the most…
  • Abstract Number: 1247 • 2015 ACR/ARHP Annual Meeting

    Methylation Analysis of HLA-B Locus in Familial Behçet Syndrome

    Eda Tahir Turanli1, Pelinsu Koprulu2, Serdal Ugurlu3, Hasan Yazici4 and Emire Seyahi3, 1Molecular Biology and Genetics Department, Istanbul Technical University, Istanbul, Turkey, 2Molecular Biology Genetics and Biotechnology Program, Istanbul Technical University, Istanbul, Turkey, 3Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Turkey, Istanbul, Turkey, 4Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey

    Background/Purpose: Our focus has been on the potential role of the epigenetic processes, mainly of the methylation, on the development of Beh�et syndrome (BS) using…
  • Abstract Number: 3049 • 2015 ACR/ARHP Annual Meeting

    Cognitive Dysfunction in Chronic Progressive Neuro-Behçet’s Disease: Comparative Study of the Brainstem and Hippocampus Region Using Brain Magnetic Resonance Imaging

    Hirotoshi Kikuchi1, Kurumi Asako1, Maki Takayama1, Shoko Iga1, Yoshitaka Kimura1, Hajime Kono1 and Shunsei Hirohata2, 1Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan, 2Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Kanagawa, Japan

    Background/Purpose: Central nervous system involvement is one of the most serious complications in Behçet's disease (BD). This condition is referred to as neuro-Behçet's disease (NB)…
  • Abstract Number: 1370 • 2015 ACR/ARHP Annual Meeting

    CD40/CD40L Pathway Is Associated with Increased Oxidative Burst and Neutrophil Extracellular Traps Release in Behcet´s Disease

    Sandro F. Perazzio1,2, Paulo Vitor Soeiro Pereira3, Alexandre W.S. Souza4, Antonio Condino-Neto3 and Luis Eduardo C. Andrade5, 1Rheumatology Division, Universidade Federal de São Paulo, Sao Paulo, Brazil, 2Fleury Medicine and Health, Sao Paulo, Brazil, 3Immunology, ICB IV - Universidade de São Paulo, São Paulo, Brazil, 4Rheumatology Division, Universidade Federal de Sao Paulo, Sao Paulo, Brazil, 5Immunology Division, Fleury Medicine and Health, São Paulo, Brazil

    Background/Purpose: Previous studies suggested that unknown plasma factors increase oxidative burst in Behçet’s disease (BD), but little is known about neutrophil extracellular traps (NET) formation.…
  • Abstract Number: 3052 • 2015 ACR/ARHP Annual Meeting

    Budd-Chiari Syndrome in Behçet’s Disease:a Retrospective Multicenter Study

    Lutfi Akyol1, Bahtiyar Toz2, Ozun Bayndır3, Orhan Zengin4, Dondu Uskudar Cansu5, Murat Yigit6, Gozde Yildirim Cetin7, Ahmet Omma8, Abdulsamet Erden9, Orhan Kucuksahin10, Senol Kobak11, Osman Cure1, Ali Ugur Unal12, Ayten Yazici13, Metin Ozgen1, Ali Sahin14, Emel Gonullu15, Suleyman Serdar Koca16, Burak Erer2, Ahmet Gul17, Kenan Aksu3, Gokhan Keser18, Ahmet Mesut Onat4, Bunyamin Kisacik4, Timucin Kasifoglu5, Ayse Cefle19, Umut Kalyoncu9 and Mehmet Sayarlioglu1, 1Department of Internal Medicine Division of Rheumatology, Ondokuz Mayıs University, Faculty of Medicine, Samsun, Turkey, 2Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, 3İnternal Medicine Division of Rheumatology, Ege University Medical Faculty, Izmir, Turkey, 4İnternal Medicine Division of Rheumatology, Gaziantep University, Faculty of Medicine, Gaziantep, Turkey, 5İnternal Medicine Division of Rheumatology, Osmangazi University, Faculty of Medicine, Eskisehir, Turkey, 6İnternal Medicine Division of Rheumatology, Pamukkale University, Faculty of Medicine, Denizli, Turkey, 7Rheumatology, Kahramanmaras University School of Medicine, Kahramanmaras, Turkey, 8Department of Internal Medicine, Rheumatology Division, Ankara Numune Hospital, Ankara, Turkey, 9Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 10Rheumatology, Yildirim Beyazit University School of Medicine, Ankara, Turkey, 11Rheumatology, Sifa University, Izmir, Turkey, 12Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, 13Rheumatology, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey, 14Department of Rheumatology, Cumhuriyet University Faculty of Medicine, Sivas, Turkey, 15Rheumatology, Osmangazi University, Faculty of Medicine, Eskisehir, Turkey, 16İnternal Medicine Division of Rheumatology, Firat University, Faculty of Medicine, Elazig, Turkey, 17Department of Internal Medicine, Rheumatology Division, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, 18Rheumatology, Ege University Medical Faculty, Izmir, Turkey, 19İnternal Medicine Division of Rheumatology, Kocaeli University, Faculty of Medicine, Kocaeli, Turkey

    Background/Purpose: Budd-Chiari syndrome (BCS), or hepatic venous outflow obstruction, is a rare and serious complication of Behçet's disease (BD). The aim of this study was…
  • Abstract Number: 1389 • 2015 ACR/ARHP Annual Meeting

    A Meta-Analysis of the Prevalence of the Ocular Manifestations in All Inflammatory Rheumatic Diseases

    Jacqueline Hayworth1 and Janet E. Pope2, 1Medicine, University of Western Ontario and U of Toronto, Toronto, ON, Canada, 2University of Western Ontario, London, ON, Canada

    Background/Purpose: Many inflammatory rheumatic diseases (IRD) are associated with ocular involvement. The prevalence of these complications is not fully known.  This meta-analysis was performed to…
  • Abstract Number: 3054 • 2015 ACR/ARHP Annual Meeting

    Takayasu’s Arteritis Associated with Behçet’s Syndrome: A Case Series of 8 Patients

    Sinem Nihal Esatoglu1, Emire Seyahi2, Serdal Ugurlu2, Gulen Hatemi2, Melike Melikoglu2, Vedat Hamuryudan3 and Sebahattin Yurdakul1, 1Rheumatology, Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Turkey, Istanbul, Turkey, 2Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Turkey, Istanbul, Turkey, 3Rheumatology, Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey

    Background/Purpose: Takayasu's arteritis (TA) and Behçet's syndrome (BS) are both systemic vasculitis of an unknown etiology, each with unique involvement pattern. TA affects aorta and…
  • Abstract Number: 3034 • 2015 ACR/ARHP Annual Meeting

    A Comparative Metabolomic Evaluation of Behcet’s Disease with Arthritis and Seronegative Arthritis Using Synovial Fluid

    Joong Kyong Ahn1, Sooah Kim2, Jungyeon Kim2, Jiwon Hwang3, Hyungjin Kim4, Hyemin Jeong5, Yeong Hee Eun6, Chan Hong Jeon7, Jaejoon Lee5, Eun-Mi Koh5, Kyoung Heon Kim2 and Hoon-Suk Cha8, 1Department of Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea, 2Department of Biotechnology, Korea University Graduate School, Seoul, South Korea, 3Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea, 4Department of medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 5Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 6Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 7Department of Internal Medicine, Soonchunhyang University College of Medicine, Bucheon, South Korea, 8Division of Rheumatology, Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea

    Background/Purpose: Behcet’s disease (BD) is a chronic, complex systemic vasculitis of unknown etiology characterized by orogenital ulcers, uveitis, and arthritis. Arthritis and arthralgias in BD…
  • Abstract Number: 3224 • 2015 ACR/ARHP Annual Meeting

    Salivary IL-1 Alpha and IL-1 Beta Levels Are Associated with Oral Mucosal Activity in Behcet’s Disease

    Nilufer Alpay Kanitez1, Bahtiyar Toz1, Feyza Berktas1, Sertan Ergun2, Meltem Koray2, Nuray Gurel Polat3, Burak Erer1 and Ahmet Gül1, 1Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, 2Department of Oral Medicine, Istanbul University, Faculty of Dentistry, Istanbul, Turkey, 3Department of Microbiology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey

    Background/Purpose: Recurrent oral aphthous ulcers are the common manifestation of the Behçet's disease (BD), and they are indistinguishable from ulcers of recurrent aphthous stomatitis (RAS).…
  • Abstract Number: 3035 • 2015 ACR/ARHP Annual Meeting

    HLA B51 and Possible Associated Autoimmune Disorders Other Than Behcets Disease: A Retrospective Cohort Study

    Luis Salayandia1, Wilmer Sibbitt Jr.1, Arthur Bankhurst2, Roderick Fields3, Gladys Cook4, Konstantin Konstantinov5 and Suzanne Emil1, 1Rheumatology, University of New Mexico, Albuquerque, NM, 2Rheum/ MSC 105550, University of NM Med Ctr, Albuquerque, NM, 3Rheumatology, University of New Mexico, Albquerque, NM, 4Rheumatology, UNM, Albuquerque, NM, 51 University Of New Mexico, University of New Mexico, Albuquerque, NM

    Background/Purpose:  The diagnostic utility of HLA B51 in association with Behcet’s disease has been clearly identified; however the correlation of HLA B51 with other autoimmune…
  • Abstract Number: 3225 • 2015 ACR/ARHP Annual Meeting

    Whole Exome Sequencing Identifies Rare Protein-Coding Variants in Behcet’s Disease

    Mikhail Ognenovski1, Paul Renauer1, Ina Koetter2, Joerg C. Henes3, Bruno Casali4, Carlo Salvarani5, Haner Direskeneli6, Kenneth M. Kaufman7 and Amr H. Sawalha1, 1Division of Rheumatology, University of Michigan, Ann Arbor, MI, 2Internal Medicine IV Rheumatology, Asklepios Klinik Altona, Hamburg, Germany, 3Department of Internal Medicine II, Rheumatology Division, University Hospital Tuebingen, Tuebingen, Germany, 4Divisione di Biologia Molecolare, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy, 5Rheumatology, Arcispedale S.Maria Nuova, Reggio Emilia, Italy, 6Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, 7Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose: Behcet’s disease (BD) is a systemic inflammatory disease characterized by recurrent oral and genital ulcers, skin lesions, uveitis, and other organ complications such as…
  • Abstract Number: 3036 • 2015 ACR/ARHP Annual Meeting

    The Association Between Behcet’s Disease, Myelodysplastic Syndrome and Trisomy 8

    Won-Seok Lee1, Yun Jung Choi2, Myong-Joo Hong3, Chang-Hoon Lee4, Myeung Su Lee5, Young Sun Suh6, Sang-Il Lee7, Yong Gon Cho8 and Wan-Hee Yoo9, 1Division of Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine of Chonbuk National University Hospital-Chonbuk National University, jeonju, South Korea, 2Division of Rheumatology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine of Chonbuk National University Hospital-Chonbuk National University, JeonJu, South Korea, 3Internal Medicine, Presbyterian Medical center, Jeonju, South Korea, 4Department of Internal Medicine, School of Medicine, Wonkwang University, Iksan, Chonbuk, South Korea, 5Internal Medicine, School of Medicine, Wonkwang University, Iksan, Chonbuk, South Korea, 6Division of Rheumatology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, South Korea, 7Division of Rheumatology, Department of Internal Medicine, Gyeongsang National University School of Medicine, Jinju, South Korea, 8Department of Laboratory medicine, Chonbuk National University Medical School and Hospital, Jeonju, South Korea, 9Division of Rhuematology, Department of Internal Medicine, Chonbuk National University Medical School and Research Institute of Clinical Medicine of Chonbuk National University Hospital-Chonbuk National University, Jeonju, South Korea

    Background/Purpose: Behcet’s disease (BD) is a systemic vasculitis, whereas myelodysplastic syndrome (MDS) is a heterogeneous group of clonal hematologic disorders characterized by ineffective hematopoiesis. Some…
  • Abstract Number: 3226 • 2015 ACR/ARHP Annual Meeting

    Increased Serum Levels of IgG Antibodies Against to Alpha-Enolase Are Associated with Severity of Oral Ulcers in Patients with Behcet’s Disease

    Shin Eui Kang1, Sang Jin Lee2,3, Jin Kyun Park2,4, Joo Youn Lee2, Eun Young Lee3, Eun Bong Lee3 and Yeong Wook Song3,5, 1Department of Molecular Medicine and Biopharmaceutical Sciences, BK 21 plus Graduate School of Convergence Science and Technology, and College of Medicine or College of Parmarcy, Seoul National University, Seoul, South Korea, 2Department of Molecular Medicine and Biopharmaceutical Sciences, BK21 plus Graduate School of Convergence Science and Technology, and College of Medicine or College of Pharmacy, Seoul National University, Seoul, South Korea, 3Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea, 4Department of Molecular Medicine and Biopharmaceutical Sciences Graduate School of Convergence Science and Technology, and College of Medicine or College of Pharmacy Seoul National University, Seoul, South Korea, 5Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology and College of Medicine Seoul National University, Seoul, South Korea

    Background/Purpose: Behcet's Disease (BD) is a chronic inflammatory disease characterized by recurrent oral and genital ulcers, skin lesions, uveitis, and arthritis. Although the etiology of…
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