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Abstracts tagged "Behcet’s syndrome"

  • Abstract Number: 1165 • 2013 ACR/ARHP Annual Meeting

    Systems Approach To The Study Of the Microbiome and Inflammatory Pathways In Oral Ulcer Tissue From Patients With Active Behςet’s Syndrome (BS)

    Cailin Sibley1, Gulen Hatemi2, Yusuf Yazici3, Yin Liu4, Steve Brooks5, Hasan Yazici6 and Raphaela Goldbach-Mansky7, 1Office of the Clinical Director, NIH / NIAMS, Bethesda, MD, 2Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, 3Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, 4Translational Autoinflammatory Disease Section, Office of the Clinical Director, NIAMS/NIH, Bethesda, MD, 5NIAMS/NIH, Bethesda, MD, 6Istanbul University, Cerrahpasa Medical Faculty, Rheumatology, Istanbul, Turkey, 7Translational Autoinflammatory Diseases Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD

    Background/Purpose: Behcet's syndrome (BS) exhibits features of both innate and acquired immunity.   Oral ulceration is the cardinal lesion which usually precedes other manifestations.  Despite the…
  • Abstract Number: 2623 • 2013 ACR/ARHP Annual Meeting

    A CT Evaluation Of Pulmonary and Cardiac Lesions In BEHÇET’S Syndrome Patients Without Pulmonary Symptoms

    Emire Seyahi1, Deniz Cebi Olgun2, SerdaL Ugurlu1, Idil Hanci3, Reona Takahashi4 and Hasan Yazici1, 1Division of Rheumatology,Department of Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, 2Department of Radiology,, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, 3Department of Neurology, Krankrenhaus Nordwest, Frankfurt am Main, Frankfurt, Germany, 4Department of Internal Medicine, Division of Rheumatology, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey

    Background/Purpose:  In Behçet’s syndrome (BS) patients with symptomatic pulmonary artery involvement (PAI) varying and multiple pulmonary parenchymal and cardiac lesions can be seen in thorax CT…
  • Abstract Number: 893 • 2013 ACR/ARHP Annual Meeting

    Association Between Human Leukocyte Antigen-B’s Amino Acid Variation and Disease-Susceptibility To Takayasu’s Arteritis

    Hajime Yoshifuji1, Chikashi Terao2, Kosaku Murakami3, Daisuke Kawabata3, Koichiro Ohmura1, Takao Fujii4, Yasushi Kawaguchi5, Hisashi Yamanaka5 and Tsuneyo Mimori1, 1Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 2Center for Genomic Medicine, Kyoto University, Kyoto, Japan, 3Dept of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 4Department of the Control for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 5Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan

    Background/Purpose: HLA-B52 and HLA-B51 are frequently seen in Asian population and are almost identical except two amino acid residues(the 63rd and 67th), but HLA-B52 is…
  • Abstract Number: 2624 • 2013 ACR/ARHP Annual Meeting

    Evaluation of Asymptomatic Venous Disease By Venous Doppler Ultrasonography in Patients With Behcet’s Disease

    Fatma Alibaz-Oner1, Emrah Karatay2, Ihsan Nuri Akpinar2, Tülin Ergun3 and Haner Direskeneli1, 1Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, 2Radiology, Marmara University, School of Medicine, Istanbul, Turkey, 3Dermatology, Marmara University, School of Medicine, Istanbul, Turkey

    Background/Purpose: One of the major causes of mortality and morbidity in Behcet’s disease (BD), especially in young males of Mediterranean origin, is vascular involvement. A…
  • Abstract Number: 2625 • 2013 ACR/ARHP Annual Meeting

    Biologic Therapy In Refractory Uveitis Of Behcet’s Syndrome: Switching and Dose Modification. Multicenter Study Of 124 Patients

    F. Ortiz-Sanjuán1, Vanesa Calvo-Río2, Ricardo Blanco3, Emma Beltrán4, Juan Sánchez-Bursón5, Marina Mesquida6, Alfredo M. Adan6, M Hernandez Grafella7, E Valls Pascual8, L Martínez-Costa9, A Sellas-Fernàndez10, Miguel Cordero-Coma11, Manuel Diaz-llopis12, David Salom12, Jl García Serrano13, Norberto Ortego13, JM Herreras14, Alejandro Fonollosa15, A Aparicio16, O Maíz17, A Blanco18, I Torre19, Cruz Fernández-Espartero20, V Jovani21, D Peitado-Lopez22, Esperanza Pato23, J Cruz24, J. Carlos Fernandez-Cid25, Elena Aurrecoechea26, M García27, M Caracuel28, Carlos Montilla29, A Atanes30, F Francisco31, S Insua32, S González-Suárez33, A Sánchez-Andrade34, F Gamero35, Luis Linares36, F Romero-Bueno37, J García38, AJ García González39, Raquel Almodovar40, E Minguez41, C Carrasco Cubero42, Alejandro Olivé Marqués43, J Vázquez44, O Ruiz Moreno45, F Jimenez-Zorzo45, J Manero45, Javier Loricera2 and Miguel Angel González-Gay1, 1Rheumatology, Hospital Universitario Marqués de Valdecilla. IFIMAV. Santander. Spain, Santander, Spain, 2Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, 3Hospital Marques de Valdecilla, Santander, Spain, 4Rheumatology, Hospital General Universitario de Valencia. Spain, Valencia, Spain, 5Hospital de Valme. Sevilla, Sevilla, Spain, 6Ophthalmology, Hospital Clínic of Barcelona, Barcelona, Spain, 7Ophthalmology, Hospital General Universitario, Valencia, Valencia, Spain, 8Rheumatology, Hospital Peset Valencia, Valencia, Spain, 9Ophthalmology, Hospital Peset Valencia, Valencia, Spain, 10Rheumatology, Hospital Val d´Hebron. Barcelona, Barcelona, Spain, 11Departament of Ophthalmology, Hospital de León, León, Spain, 12Department of Ophthalmology, Hospital Universitario La Fe de Valencia, Valencia, Spain, 13Hospital San Cecilio. Granada, Granada, Spain, 14Hospital Universitario, IOBA. Valladolid, Valladolid, Spain, 15Ophtalmology Service, Hospital de Cruces. Bilbao, Baracaldo, Spain, 16Rheumatology., Hospital de Toledo., Toledo, Spain, 17Rheumatology, Hospital Donosti San Sebastian, San Sebastián, Spain, 18Ophthalmology., Hospital Donosti San Sebastian, San Sebastián, Spain, 19Rheumatology., Hospital Basurto. Bilbao, Bilbao, Spain, 20Servicio de Reumatología, Hospital Universitario de Móstoles. Madrid, Madrid, Spain, 21Rheumatology., Hospital General de Alicante., Alicante, Spain, 22Rheumatology, Hospital Universitario La Paz Madrid, Madrid, Spain, 23Rheumatology, Hospital Clínico San Carlos. Madrid, Madrid, Spain, 24Rheumatology, Hospital de Pontevedra, Pontevedra, Spain, 25Departament of Ophthalmology, Hospital de Pontevedra, Pontevedra, Spain, 26Rheumatology, Hospital Sierrallana. Torrelavega, Torrelavega, Spain, 27Rheumatology., Hospital La Princesa. Madrid, Madrid, Spain, 28Rheumatology., Hospital de Córdoba., Córdoba, Spain, 29Rheumatology Service, Hospital Universitario de Salamanca, Salamanca, Spain, 30Rheumatology., HUCA La Coruña., A Coruña, Spain, 31Rheumatology., Hospital Doctor Negrín Canarias., Canarias, Spain, 32Rheumatology., Hospital Universitario Santiago de Compostela, Santiago de Compostela, Spain, 33Rheumatology., Hospital Cabueñes, Gijón, Gijón, Spain, 34Rheumatology., Hospital Lucus Augusti Lugo, Lugo, Spain, 35Rheumatology., Hospital San Pedro Alcantara Caceres, Caceres, Spain, 36Rheumatology, Hospital Universitario Virgen de la Arrixaca. Murcia, Murcia, Spain, 37Rheumatology., Fundación Jimenez Díaz. Madrid, Madrid, Spain, 38Rheumatology, Hospital 12 de Octubre. Madrid, Madrid, Spain, 39Rheumatology., Hospital 12 de Octubre. Madrid, Madrid, Spain, 40Rheumatology Unit, Hospital Universitario Fundación Alcorcón. Madrid, Alcorcon. Madrid, Spain, 41Ophthalmology, Hospital Clínico de Zaragoza, Zaragoza, Spain, 42Rheumatology., Hospital de Mérida, Mérida, Spain, 43Hospital Germans Trias i Pujol. Badalona, Barcelona, Spain, 44Rheumatology, Hospital de Ferrol. A Coruña, A Coruña, Spain, 45Hospital Universitario Miguel Servet. Zaragoza, Zaragoza, Spain

    Background/Purpose: Several situations can be observed in patients undergoing biologic therapy in uveitis associated to Behçet´s syndrome (BS): a) Patients are switched to another therapy…
  • Abstract Number: 2627 • 2013 ACR/ARHP Annual Meeting

    Prognostic Factors Of Visual Function In The Treatment With Infliximab For Uveitis Of Behçet’s Disease

    Akihiko Nakabayashi1, Toru Hirano2, Yoshihiro Hishitani2, Keisuke Hagihara3, Kei Nakai4, Kouji Nishida4 and Atsushi Kumanogoh2, 1Department of Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine, Suita, Japan, 2Respiratory Medicine, Allergy and Rheumatic Diseases, Osaka University Graduate School of Medicine, Suita, Japan, 3Department of Kampo Medicine, Osaka University Graduate School of Medicine, Suita, Japan, 4Department of Ophthalmology, Osaka University Graduate School of Medicine, suita, Japan

    Background/Purpose: Infliximab, a chimeric monoclonal antibody against TNF-a, is expected to improve prognosis of visual function in patients with severe and refractory uveitis of Behçet's…
  • Abstract Number: 2628 • 2013 ACR/ARHP Annual Meeting

    Immunogenicity Of Infliximab Modulates Efficacy and Safety In Behcet’s Disease Patients With Uveitis

    Mitsuhiro Takeno1, Kayo Terauchi1, Yohei Kirino1,2, Ryusuke Yoshimi1, Nobuhisa Mizuki2, Etsuko Shibuya3 and Yoshiaki Ishigatsubo2, 1Department of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan, 2Yokohama City University Graduate School of Medicine, Yokohama, Japan, 3Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, Yokohama, Japan

    Background/Purpose: Infliximab (IFX) suppresses ocular attacks in Behcet’s disease (BD) with uveitis, resulting in favorable long-term visual prognosis. However, some patients had ocular attacks which…
  • Abstract Number: 181 • 2012 ACR/ARHP Annual Meeting

    Thiopurine S-Methyltransferase Levels in Patients with Behçet’s Disease

    Hakan Emmungil1, Melike Kalfa2, Raika Durusoy3, Figen Yargucu Zihni2, Gokhan Keser4 and Kenan Aksu2, 1Rheumatology, Mersin State Hospital, Mersin, Turkey, 2Dept. of Internal Medicine, Division of Rheumatology, Ege University, Dept. of Internal Medicine, Division of Rheumatology, Ege University, Izmir, Turkey, 3Department of Public Health, Ege University, Department of Public Health, Ege University, Izmir, Turkey, 4Dept. of Internal Medicine, Division of Rheumatology, Ege University School of Medicine, Izmir, Turkey

    Background/Purpose: Azathioprine (AZA) is an immunosuppressive agent which is widely used not only for the treatment of Behcet’s disease (BD), but also for the treatment…
  • Abstract Number: 183 • 2012 ACR/ARHP Annual Meeting

    A Strong Association Between HLA-A*26 and Behçet’s Syndrome in Japanese Patients: From Two-Center Cohort Study of Behçet’s Syndrome

    Tatsuo Kobayashi1, Mitsumasa Kishimoto2, Kazuki Yoshida1, Yuri Ohara3, Hiroto Nakano1, Masahiro Minoda1, Hideto Oshikawa1 and Kazuo Matsui1, 1Rheumatology, Kameda Medical Center, Kamogawa City, Chiba, Japan, 2Division of Allergy and Rheumatology, St. Luke's International Hospital, Chuo-ku, Tokyo, Japan, 3Allergy and Rheumatology, St. Luke's International Hospital, Chuo-ku, Tokyo, Japan

    Background/Purpose: An association between Behçet’s Syndrome (BS) and HLA-B*51 is widely reported among many different ethnic groups. Recently, a few reports from Taiwan, Greece and…
  • Abstract Number: 184 • 2012 ACR/ARHP Annual Meeting

    The Retrospective Review of 39 Intestinal Behcet’s Disease Focusing On the Requirement for the Immunosuppresive Drugs Other Than Corticosteroid

    Yoshitaka Kimura1, Kurumi Asako2, Hirotoshi Kikuchi2, Akiteru Takeuchi3 and Hajime Kono2, 1Department of Internal Medicine, Teikyo University school of medecine, Tokyo, Japan, 2Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan, 36-7-8 Arakawa, Tokyo, Japan

    Background/Purpose: To examine the demography, clinical characteristics, features of intestinal lesions, treatment, and prognosis in patients with the intestinal Behcet’s disease currently followed at a…
  • Abstract Number: 185 • 2012 ACR/ARHP Annual Meeting

    Long-Term Efficacy and Safety of Tumour Necrosis Factor Antagonists for Patients with Behçet’s Disease with Uveitis As Main Involvement

    M. Victoria Hernández1, Marina Mesquida2, Gerard Espinosa3, Victor Llorens2, Laura Pelegrin2, Juan D. Cañete4, Ricard Cervera5, Alfredo M. Adan2 and Raimon Sanmarti1, 1Arthritis Unit. Rheumatology Department, Hospital Clínic of Barcelona, Barcelona, Spain, 2Ophthalmology, Hospital Clínic of Barcelona, Barcelona, Spain, 3Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Barcelona, Spain, 4Rheumatology, Hospital Clínic of Barcelona. IDIBAPS. University of Barcelona, Barcelona, Spain, 5Autoimmune Diseases, Hospital Clínic of Barcelona, Barcelona, Spain

    Background/Purpose: To assess the long-term efficacy and safety of tumour necrosis factor (TNF) antagonists (infliximab [IFX], adalimumab [ADA] and golimumab) for the treatment of patients…
  • Abstract Number: 2385 • 2012 ACR/ARHP Annual Meeting

    Prognostic Impact of HLA-B*51 and HLA–A*26:01 On Ocular Behcet’s Disease

    Jun Won Park1, Eun Ha Kang2, Hye Won Kim1, Chaerin Park3, Hyeong Gon Yu3, Eun Young Lee1, Yun Jong Lee4, Eun Bong Lee1 and Yeong Wook Song5, 1Internal Medicine, Seoul National University Hospital, Seoul, South Korea, 2Internal Medicine, Seoul National University Bundang Hospital, Seongnam-si, South Korea, 3Ophthalmology, Seoul National University Hospital, Seoul, South Korea, 4Division of Rheumatology, Department of Internal Medicine, Rheumatology, Seoul National University, Seoul, South Korea, 5Division of Rheumatology, Department of Internal Medicine, Seoul National University, Seoul, South Korea

    Background/Purpose: To investigate the prognostic implication of HLA-B*51 and HLA-A*26:01on visual outcome in Korean Behcet’s disease (BD) patients with uveitis. Methods: Seventy-seven Korean BD patients…
  • Abstract Number: 186 • 2012 ACR/ARHP Annual Meeting

    Long-Term Infliximab Therapy in Patients with Behcet’s Disease Is Well Tolerated without Increasing Risk of Serious Infections

    Sho Ueda, Hiroshi Tsukamoto, Yasushi Inoue, Masahiro Ayano, Satomi Hisamoto, Naoko Ueki, Atsushi Tanaka, Shun-ichiro Ohta, Naoyasu Ueda, Yojiro Arinobu, Hiroaki Niiro, Takahiko Horiuchi and Koichi Akashi, Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan

    Background/Purpose: Infliximab (IFX) is a monoclonal antibody against tumor necrosis factor-a (TNF-a) and is increasingly used in various immune-related diseases including rheumatoid arthritis (RA), ankylosing…
  • Abstract Number: 2394 • 2012 ACR/ARHP Annual Meeting

    Fibromyalgia in Behçet’s Disease Is Associated with Disease Activity

    Meryem Can1, Fatma Alibaz-Öner2, Sibel Yılmaz-Öner3, Birkan İlhan4, Tülin Ergun5, Gonca Mumcu6 and Haner Direskeneli7, 1Department of Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, 2Department of Rheumatology, Marmara University School of Medicine, Turkey, 3Department of Rheumatology, Marmara University School of Medicine, Istanbul, Turkey, 4Department of Internal Medicine, Marmara University School of Medicine, Istanbul, Turkey, 5Dermatology, Marmara University, School of Medicine, Istanbul, Turkey, 6Department of Health Management, Marmara University, Faculty of Health Sciences, Istanbul, Turkey, 7Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey

    Background/Purpose: Studies on the relationship between Fibromyalgia (FM), a generalized pain disorder with up to 2% prevelance and Behcet’s Disease (BD), a systemic, inflammatory vasculitis,…
  • Abstract Number: 2369 • 2012 ACR/ARHP Annual Meeting

    Aspects of Innate Immunity in Behçet´s Disease: A Model of Autoinflammatory Disease?

    Sandro F. Perazzio1, Paulo Vitor Soeiro Pereira2, Alexandre Wagner S. de Souza3, Antonio Condino-Neto2 and Luis Eduardo C. Andrade4, 1Rheumatology, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil, 2Immunology, ICB IV - Universidade de São Paulo, São Paulo, Brazil, 3Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, 4Rheumatology Division, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil

    Background/Purpose: Behçet's disease (BD) is a systemic vasculitis of unknown etiopathogenesis. Increased neutrophil activation has been previously shown in BD patients and it is unclear…
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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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