Abstracts tagged "Behcet’s syndrome"

Abstract Number: 2616 • 2013 ACR/ARHP Annual Meeting
Ischemia-Modified Albumin : A Novel Marker of Vascular Involvement in Behcet’s Disease ?
Erhan Capkin¹, Murat Karkucak², Mehmet Kola³, Adem Karaca², süleyman Caner Karahan⁴, Aysegul Sumer⁴, Arzu Aydin Capkin⁵, Ferhat Gokmen² and Refik Ali Sari⁶, ¹rheumatolgy, trabzon, Turkey, ²rheumatology, trabzon, Turkey, ³oftalmology, trabzon, Turkey, ⁴biochemistry, trabzon, Turkey, ⁵dermatology, trabzon, Turkey, ⁶immunology and allergy, trabzon, Turkey
Background/Purpose: The etiology and pathogenesis of Behçet’s disease (BD) are not yet well understood, but immunoregulatory abnormalities have been proposed as pathogenic mechanisms. Ischemia-modified albumin…
Abstract Number: 1879 • 2013 ACR/ARHP Annual Meeting
Major Histocompatibility Complex Class I Molecules Contribute To Behçet’s Disease Risk Through Both Innate and Adaptive Immune Interactions
Michael J. Ombrello^1,2, Yohei Kirino^2,3, Paul de Bakker⁴, Ahmet Gül⁵, Elaine F. Remmers⁶ and Daniel L. Kastner⁷, ¹Translational Genetics and Genomics Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ²National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, ³Department of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan, ⁴Medical Genetics, University Medical Center Utrecht, Utrecht, Netherlands, ⁵Department of Internal Medicine, Rheumatology Division, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ⁶Inflammatory Disease Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, ⁷Inflammatory Disease Section, National Human Genome Research Institute, Bethesda, MD
Background/Purpose: Behçet's Disease (BD) is a complex genetic disease of unknown etiology that is characterized by inflammatory lesions of the eyes, skin, and oro-genital mucosa.…
Abstract Number: 2618 • 2013 ACR/ARHP Annual Meeting
Bipolar Disorders May Represent a Primary Feature Of Behçet’s Disease
Rosaria Talarico¹, Laura Palagini², Elena Elefante³, Claudia Ferrari⁴, Chiara Stagnaro³, Chiara Baldini³, Chiari Tani³, Marta Mosca⁴ and Stefano Bombardieri³, ¹Rheumatology Unit, Pisa, Italy, ²University of Pisa, Psychiatry Unit, Department of Neuroscience, Pisa, Italy, ³University of Pisa, Rheumatology Unit, Pisa, Italy, ⁴Rheumatology Unit, University of Pisa, Pisa, Italy
Background/Purpose: Frequency of psychiatric disorders in BD is a debated issue: while some experts attribute their presence to the chronicity of the illness, others think…
Abstract Number: 1750 • 2013 ACR/ARHP Annual Meeting
Short and Long-Term Biological Therapy In Refractory Uveitis Of Behcet’s Syndrome. Multicenter Study Of 124 Patients
Francisco Ortiz-Sanjuan¹, Vanesa Calvo-Río², Ricardo Blanco³, Emma Beltrán⁴, Juan Sánchez-Bursón⁵, Marina Mesquida⁶, Alfredo M. Adan⁶, M Hernandez Grafella⁷, E Valls Pascual⁸, L Martínez-Costa⁹, Agustí Sellas-Fernàndez¹⁰, Miguel Cordero-Coma¹¹, Manuel Diaz-llopis¹², David Salom¹², Jl García Serrano¹³, Norberto Ortego¹³, JM Herreras¹⁴, Alejandro Fonollosa¹⁵, A Aparicio¹⁶, O Maíz¹⁷, A Blanco¹⁸, I Torre¹⁹, Cruz Fernández-Espartero²⁰, V Jovani²¹, D Peitado-Lopez²², Esperanza Pato²³, J Cruz²⁴, J. Carlos Fernandez-Cid²⁵, E. Aurrecoechea²⁶, M García²⁷, M Caracuel²⁸, Carlos Montilla²⁹, A Atanes³⁰, F Francisco³¹, S Insua³², S González-Suárez³³, A Sánchez-Andrade³⁴, F Gamero³⁵, Luis Linares³⁶, F Romero-Bueno³⁷, AJ García González³⁸, Raquel Almodovar³⁹, E Minguez⁴⁰, C Carrasco Cubero⁴¹, Alejandro Olive Marques⁴², J Vázquez⁴³, O Ruiz Moreno⁴⁴, F Jimenez-Zorzo⁴⁴, J Manero⁴⁴, Javier Loricera¹ and Miguel Angel González-Gay¹, ¹Rheumatology, Hospital Universitario Marqués de Valdecilla. IFIMAV. Santander. Spain, Santander, Spain, ²Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Spain, Santander, Spain, ³Hospital Marques de Valdecilla, Santander, Spain, ⁴Rheumatology, Hospital General Universitario de Valencia. Spain, Valencia, Spain, ⁵Hospital de Valme. Sevilla, Sevilla, Spain, ⁶Ophthalmology, Hospital Clínic of Barcelona, Barcelona, Spain, ⁷Ophthalmology, Hospital General Universitario, Valencia, Valencia, Spain, ⁸Rheumatology, Hospital Peset Valencia, Valencia, Spain, ⁹Ophthalmology, Hospital Peset Valencia, Valencia, Spain, ¹⁰Rheumatology, Hospital Val d´Hebron. Barcelona, Barcelona, Spain, ¹¹Departament of Ophthalmology, Hospital de León, León, Spain, ¹²Department of Ophthalmology, Hospital Universitario La Fe de Valencia, Valencia, Spain, ¹³Hospital San Cecilio. Granada, Granada, Spain, ¹⁴Hospital Universitario, IOBA. Valladolid, Valladolid, Spain, ¹⁵Ophtalmology Service, Hospital de Cruces. Bilbao, Bilbao, Spain, ¹⁶Rheumatology., Hospital de Toledo., Toledo, Spain, ¹⁷Rheumatology, Hospital Donosti San Sebastian, San Sebastián, Spain, ¹⁸Ophthalmology., Hospital Donosti San Sebastian, San Sebastián, Spain, ¹⁹Rheumatology., Hospital Basurto. Bilbao, Bilbao, Spain, ²⁰Servicio de Reumatología, Hospital Universitario de Móstoles, Madrid, Spain, ²¹Rheumatology., Hospital General de Alicante., Alicante, Spain, ²²Rheumatology, Hospital Universitario La Paz Madrid, Madrid, Spain, ²³Rheumatology, Hospital Clínico San Carlos. Madrid, Madrid, Spain, ²⁴Rheumatology, Hospital de Pontevedra, Pontevedra, Spain, ²⁵Departament of Ophthalmology, Hospital de Pontevedra, Pontevedra, Spain, ²⁶Hospital Sierrallana. Torrelavega, Torrelavega, Spain, ²⁷Rheumatology., Hospital La Princesa. Madrid, Madrid, Spain, ²⁸Rheumatology., Hospital de Córdoba., Córdoba, Spain, ²⁹Unit Rheumatology, Hospital Universitario de Salamanca, Salamanca, Spain, ³⁰Rheumatology., HUCA La Coruña., A Coruña, Spain, ³¹Rheumatology., Hospital Doctor Negrín Canarias., Canarias, Spain, ³²Rheumatology., Hospital Universitario Santiago de Compostela, Santiago de Compostela, Spain, ³³Rheumatology., Hospital Cabueñes, Gijón, Gijón, Spain, ³⁴Rheumatology., Hospital Lucus Augusti Lugo, Lugo, Spain, ³⁵Rheumatology., Hospital San Pedro Alcantara Caceres, Caceres, Spain, ³⁶Rheumatology, Hospital Universitario Virgen de la Arrixaca. Murcia, Murcia, Spain, ³⁷Rheumatology., Fundación Jimenez Díaz. Madrid, Madrid, Spain, ³⁸Rheumatology., Hospital 12 de Octubre. Madrid, Madrid, Spain, ³⁹Rheumatology Unit, Hospital Universitario Fundación Alcorcón. Madrid, Alcorcon. Madrid, Spain, ⁴⁰Ophthalmology, Hospital Clínico de Zaragoza, Zaragoza, Spain, ⁴¹Rheumatology., Hospital de Mérida, Mérida, Spain, ⁴²Hospital Germans Trias i Pujol. Badalona, Barcelona, Spain, ⁴³Rheumatology, Hospital de Ferrol. A Coruña, A Coruña, Spain, ⁴⁴Hospital Universitario Miguel Servet. Zaragoza, Zaragoza, Spain
Background/Purpose: To evaluate short and long-term response to biological therapy in uveitis associated to Behçet´s syndrome refractory to standard systemic treatment. Methods: Multicenter study of…
Abstract Number: 2619 • 2013 ACR/ARHP Annual Meeting
Suicidal Ideation Among Patients With Behcet’s Syndrome
Didem Uzunaslan¹, Caner Saygin¹, Gulen Hatemi², Koray Tascilar¹, Hasan Yazici³ and Vedat Hamuryudan⁴, ¹University of Istanbul, Cerrahpasa Medical Faculty, Rheumatology, Istanbul, Turkey, ²Rheumatology, Istanbul University, Cerrahpasa Medical Faculty, Rheumatology, Istanbul, Turkey, ³Cerrahpasa Medical Faculty University of Istanbul, Istanbul University, Cerrahpasa Medical Faculty, Rheumatology, Istanbul, Turkey, ⁴Division of Rheumatology, Istanbul University, Cerrahpasa Medical Faculty, Rheumatology, Istanbul, Turkey
Background/Purpose: An increased frequency of depression has been reported in Behcet’s syndrome (BS). While an increased suicidal ideation has been reported in other chronic rheumatologic conditions, this…
Abstract Number: 1751 • 2013 ACR/ARHP Annual Meeting
Ethnicity-Related Differences In Behçet’s Disease In a French Multiethnic Country
David Saadoun¹, Mathieu Resche Rigon², Bertrand Wechsler³, Du Le Thi Huong⁴, Jean-Charles Piette¹ and Patrice Cacoub⁵, ¹Groupe Hospitalier Pitié Salpétrière, Service de Médecine Interne, DHU i2B, Paris, France, ²Department of Internal Medicine and Laboratory I3 “Immunology, Immunopathology, Immunotherapy”, UMR CNRS 7211, INSERM U959, Groupe Hospitalier Pitié-Salpetrière, Université Pierre et Marie Curie, Paris 6, Paris, France, Paris, France, ³Department of Internal Medicine 2. Referal center for SLE/APS, CHU Pitié-Salpêtrière, Paris, France, ⁴Internal Medicine, Groupe Hospitalier Pitié-Salpétrière, Paris, France, ⁵Internal Medicine, Assistance Publique-Hôpitaux de Paris, Hopital Pitié-Salpétrière, Paris, France
Background/Purpose: It has been suggested that Behçet’s disease (BD) varies in its phenotypic expression in different ethnies and in different countries indicating that both environmental…
Abstract Number: 2620 • 2013 ACR/ARHP Annual Meeting
Development Of De Novo Major Involvement During The Follow-Up In Behçet’s Disease
Claudia Ferrari¹, Rosaria Talarico², Chiara Stagnaro³, Anna d'Ascanio⁴, Chiara Tani³, Chiara Baldini³, Marta Mosca¹ and Stefano Bombardieri³, ¹Rheumatology Unit, University of Pisa, Pisa, Italy, ²Rheumatology Unit, Pisa, Italy, ³University of Pisa, Rheumatology Unit, Pisa, Italy, ⁴Malattie muscolo-scheletriche e cutanee, Rheumatology Unit, Pisa, Italy
Background/Purpose: Behçet’s disease (BD) is globally characterized by a variable spectrum of disease profile: while prevalent muco-cutaneous lesions and arthritis represent the only clinical features…
Abstract Number: 1753 • 2013 ACR/ARHP Annual Meeting
An Outcome Survey Of 40 Patients With Budd-Chiari Syndrome Due To BEHÇET’S Syndrome Followed By A Single Center
Emire Seyahi¹, SerdaL Ugurlu², Erkan Caglar³, Fatih Kantarci⁴, Abdullah Sonsuz⁵, Sebahattin Yurdakul² and Hasan Yazici², ¹Division of Rheumatology,Department of Medicine,Cerrahpasa Medical Faculty, University of Istanbul, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, ²Division of Rheumatology,Department of Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, ³Division of Gastroenterology, Department of Internal Medicine, Bakirkoy Research and Training Hospital, Istanbul, Turkey, ⁴Department of Radiology, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, ⁵Division of Gastroenterology,Department of Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey
Background/Purpose: Budd-Chiari syndrome is a rare complication of BS with a frequency of < 1 %, and carries a high mortality rate. In a previous…
Abstract Number: 2621 • 2013 ACR/ARHP Annual Meeting
Venous Claudication Is A Severe and Frequent Symptom In BEHCET’S Syndrome
SerdaL Ugurlu¹, Emire Seyahi¹, Veysel Oktay², Zerrin Yigit², Serdar Kucukoglu² and Hasan Yazici¹, ¹Division of Rheumatology,Department of Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, ²Department of Cardiology, Cardiology Institute, University of Istanbul, Istanbul, Turkey
Background/Purpose: In a previous cross-sectional questionnaire survey, we had shown that intermittent claudication was significantly more common among BS patients when compared to healthy controls,…
Abstract Number: 1703 • 2013 ACR/ARHP Annual Meeting
High Density Genotyping Of Immune-Related Disease Genes Identifies 7 New Susceptibility Loci For Behçet’s Disease
Masaki Takeuchi^1,2, Nobuhisa Mizuki², Akira Meguro², Michael J. Ombrello³, Colleen Satorius⁴, Yohei Kirino², Tatsukata Kawagoe², Duran Ustek⁵, Ilknur Tugal-tutkun⁶, Emire Seyahi⁷, Yilmaz Ozyazgan⁷, Shigeaki Ohno⁸, Atsuhisa Ueda², Yoshiaki Ishigatsubo², Ahmet Gül^6,9, Daniel L. Kastner⁴ and Elaine Remmers⁴, ¹Medical Genetics Branch, Inflammation Disease Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, ²Yokohama City University Graduate School of Medicine, Yokohama, Japan, ³Translational Genetics and Genomics Unit, National Institute of Arthritis Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁴Inflammatory Disease Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, ⁵Institute of Experimental Medicine, Istanbul University, Istanbul, Turkey, ⁶Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey, ⁷Cerrahpasa Faculty of Medicine, Istanbul University, Istanbul, Turkey, ⁸Hokkaido University Graduate School of Medicine, Hokkaido, Japan, ⁹Department of Internal Medicine, Rheumatology Division, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey
Background/Purpose: Genome-wide association studies have revealed susceptibility genes for many genetically complex diseases. The Immunochip is a custom array with 196,524 markers in 186 loci…
Abstract Number: 2622 • 2013 ACR/ARHP Annual Meeting
Comparison Of Different Methods Of Skin Pathergy Test In Patients With Behçet’s Syndrome
Aysegul Lacin¹, Cigdem Atan Uzun¹, Zafer Gunendi² and Feride Gogus¹, ¹Physical Medicine and Rehabilitation, Division of Rheumatology, Gazi University Faculty of Medicine, Ankara, Turkey, ²Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Gazi University Faculty of Medicine, Ankara, Turkey
Background/Purpose: Skin pathergy test (SPT) has a diagnostic value in Behçet’s syndrome (BS). There are different descriptions of the test which may effect its positivity rate.…
Abstract Number: 1165 • 2013 ACR/ARHP Annual Meeting
Systems Approach To The Study Of the Microbiome and Inflammatory Pathways In Oral Ulcer Tissue From Patients With Active Behςet’s Syndrome (BS)
Cailin Sibley¹, Gulen Hatemi², Yusuf Yazici³, Yin Liu⁴, Steve Brooks⁵, Hasan Yazici⁶ and Raphaela Goldbach-Mansky⁷, ¹Office of the Clinical Director, NIH / NIAMS, Bethesda, MD, ²Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, ³Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ⁴Translational Autoinflammatory Disease Section, Office of the Clinical Director, NIAMS/NIH, Bethesda, MD, ⁵NIAMS/NIH, Bethesda, MD, ⁶Istanbul University, Cerrahpasa Medical Faculty, Rheumatology, Istanbul, Turkey, ⁷Translational Autoinflammatory Diseases Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD
Background/Purpose: Behcet's syndrome (BS) exhibits features of both innate and acquired immunity. Oral ulceration is the cardinal lesion which usually precedes other manifestations. Despite the…
Abstract Number: 2623 • 2013 ACR/ARHP Annual Meeting
A CT Evaluation Of Pulmonary and Cardiac Lesions In BEHÇET’S Syndrome Patients Without Pulmonary Symptoms
Emire Seyahi¹, Deniz Cebi Olgun², SerdaL Ugurlu¹, Idil Hanci³, Reona Takahashi⁴ and Hasan Yazici¹, ¹Division of Rheumatology,Department of Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, ²Department of Radiology,, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, ³Department of Neurology, Krankrenhaus Nordwest, Frankfurt am Main, Frankfurt, Germany, ⁴Department of Internal Medicine, Division of Rheumatology, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey
Background/Purpose: In Behçet’s syndrome (BS) patients with symptomatic pulmonary artery involvement (PAI) varying and multiple pulmonary parenchymal and cardiac lesions can be seen in thorax CT…
Abstract Number: 893 • 2013 ACR/ARHP Annual Meeting
Association Between Human Leukocyte Antigen-B’s Amino Acid Variation and Disease-Susceptibility To Takayasu’s Arteritis
Hajime Yoshifuji¹, Chikashi Terao², Kosaku Murakami³, Daisuke Kawabata³, Koichiro Ohmura¹, Takao Fujii⁴, Yasushi Kawaguchi⁵, Hisashi Yamanaka⁵ and Tsuneyo Mimori¹, ¹Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, ²Center for Genomic Medicine, Kyoto University, Kyoto, Japan, ³Dept of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, ⁴Department of the Control for Rheumatic Diseases, Graduate School of Medicine, Kyoto University, Kyoto, Japan, ⁵Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan
Background/Purpose: HLA-B52 and HLA-B51 are frequently seen in Asian population and are almost identical except two amino acid residues(the 63rd and 67th), but HLA-B52 is…
Abstract Number: 2624 • 2013 ACR/ARHP Annual Meeting
Evaluation of Asymptomatic Venous Disease By Venous Doppler Ultrasonography in Patients With Behcet’s Disease
Fatma Alibaz-Oner¹, Emrah Karatay², Ihsan Nuri Akpinar², Tülin Ergun³ and Haner Direskeneli¹, ¹Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, ²Radiology, Marmara University, School of Medicine, Istanbul, Turkey, ³Dermatology, Marmara University, School of Medicine, Istanbul, Turkey
Background/Purpose: One of the major causes of mortality and morbidity in Behcet’s disease (BD), especially in young males of Mediterranean origin, is vascular involvement. A…

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