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Abstracts tagged "axial spondyloarthritis"

  • Abstract Number: 1292 • 2016 ACR/ARHP Annual Meeting

    Performance of 18fluoride Sodium Positron Emission Tomography with Computed Tomography to Assess Inflammatory and Structural Sacroiliitis Respectively on Magnetic Resonance Imaging and Computed Tomography in Axial Spondyloarthritis

    Marie Raynal1, ouichka remy2, Julian Melchior1, Isabelle Chary-Valckenaere3, Willy Ngueyon Sime4, Walter P. Maksymowych5, Robert G. Lambert6 and Damien Loeuille3, 1Rheumatology, CHRU Nancy, Nancy, France, 2rheumatology, CHRU Nancy, Vandoeuvre les Nancy, France, 3Rheumatology, CHRU Nancy, Vandoeuvre les Nancy, France, 4University of Lorraine, Nancy, France, 5Medicine, University of Alberta, Edmonton, AB, Canada, 6Radiology, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: to assess increased SIJ uptakes on 18-FNa (an osteoblastic tracer) PET/CT according to a qualitative and quantitative approach and to compare with MRI SIJ…
  • Abstract Number: 1667 • 2016 ACR/ARHP Annual Meeting

    Diagnostic Value of Anti-CD74 Antibodies in Axial Spondyloarthritis: Results from a Population with Low HLA-B27 Prevalence Background

    Nelly Ziade1, Fouad Fayad1, Iyad Mallak2, Georges Merheb3, Torsten Witte4 and Xenofon Baraliakos5, 1Rheumatology, Hotel Dieu de France Hospital and Saint Joseph University, Beirut, Lebanon, 2Radiology, Hotel-Dieu de France and Saint-Joseph University, Beirut, Lebanon, 3Internal Medicine, Notre Dame des Secours University Hospital, Jbeil, Lebanon, 4Department of Clinical Immunology and Rheumatology, Hannover Medical School, Hannover, Germany, 5Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany

    Background/Purpose: Axial spondyloarthritis (axSpA) is still frequently diagnosed late and its pathogenesis is still unclear. Although a strong genetic association of axSpA with HLA-B27 is…
  • Abstract Number: 691 • 2015 ACR/ARHP Annual Meeting

    Standards for the Classification of Non-Radiographic Axial Spondyloarthritis: A European Real World Study

    Tim Holbrook1, Robert Wood1, Christopher Black2, Xiaohan Hu2 and Sumesh Kachroo2, 1Adelphi Real World, Macclesfield, United Kingdom, 2CORE, Merck & Co., Inc., Rahway, NJ

    Background/Purpose: Classification of non-radiographic axial spondyloarthritis (nr-axSpA) requires the presence of Assessment of Spondyloarthritis international Society (ASAS) criteria for AxSpA, without radiologic evidence of sacroiliitis…
  • Abstract Number: 2878 • 2015 ACR/ARHP Annual Meeting

    Treating Axial Spondyloarthritis to Target: Influence of the Population Characteristics and Comorbidities in Reaching Ankylosing Spondylitis Disease Activity Score (ASDAS) Inactive Disease in a Cohort of Patients Treated with Tnfalpha Inhibitors Agents

    Sara Monti, Veronica Codullo, Vittorio Grosso, Silvia Breda, Carlomaurizio Montecucco and Roberto Caporali, Division of Rheumatology, University of Pavia, IRCCS Foundation Policlinico S. Matteo, Pavia, Italy

    Background/Purpose: The treat to target strategy (T2T), aiming at inactive disease (ID), has become the recommended approach also in the field of axial-SpA (axSpA) (1). …
  • Abstract Number: 696 • 2015 ACR/ARHP Annual Meeting

    Current and Past Smoking Are Associated with Functional Impairement and Increased Disease Activity in Axial Spondyloarthritis: Systematic Review and Meta-Analysis

    Kristina SCHREIBER1, Thomas Barnetche2, BG Combe3, Jacques Morel1 and Claire I. Daien1, 1Department of rheumatology, Lapeyronie Hospital and Montpellier University, Montpellier, France, 2Rheumatology Department, Pellegrin University Hospital, BORDEAUX, France, 3Lapeyronie, Montpellier, France

    Background/Purpose: The influence of smoking on the development of rheumatoid arthritis, the severity of the disease and the response to treatment is well established. The…
  • Abstract Number: 2885 • 2015 ACR/ARHP Annual Meeting

    Long-Term Effects of Etanercept on Patient-Reported Outcomes in Early Non-Radiographic Axial Spondyloarthritis: 104-Week Results of a Phase III Study

    Filip van Den Bosch1,2, Edit Drescher3, Jan Rosa4, Ronald Pedersen5, Randi Bonin6, Bonnie Vlahos7, Jack F Bukowski6 and Sameer Kotak8, 1Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, 2Rheumatology, Ghent University Hospital, Ghent, Belgium, 3Csolnoky Ferenc Hospital, Veszprém, Hungary, 4Mediscan Group, Prague, Czech Republic, 5Department of Biostatistics, Pfizer, Collegeville, PA, 6Clinical Affairs, Pfizer, Collegeville, PA, 7GIPB - Clinical Sciences, Pfizer, Collegeville, PA, 8Global Health and Value, Pfizer, New York, NY

    Background/Purpose: In patients with active, NSAID-resistant, non-radiographic axial spondyloarthritis (nr-axSpA) who participated in the multiphase, randomized, placebo (PBO)-controlled EMBARK study (ClinicalTrials.gov identifier: NCT01258738), health-related quality-of-life…
  • Abstract Number: 697 • 2015 ACR/ARHP Annual Meeting

    Identification Methods for Axial Spondyloarthritis in American Veterans

    Jessica Walsh1, Jianwei Leng2, Brian Breviu3, Daniel Clegg4, Tao He2 and Brian Sauer5, 1Division of Rheumatology, Salt Lake City Veteran Affairs and University of Utah Medical Centers, Salt Lake City, UT, 2Salt Lake City Veteran Affairs and University of Utah Medical Centers, Salt Lake City, UT, 3Department of Internal Medicine, Salt Lake City Veteran Affairs and University of Utah Medical Centers, Salt Lake City, UT, 4Rheumatology, Salt Lake City Veteran Affairs and University of Utah Medical Centers, Salt Lake City, UT, 5Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT

    Background/Purpose: Current methods for identifying people with axial spondyloarthritis (AxSpA) in large datasets are inadequate because billing codes for most types of spondyloarthrtis (SpA) do…
  • Abstract Number: 2893 • 2015 ACR/ARHP Annual Meeting

    Quality of Life in Patients with Active Nonradiographic Axial Spondyloarthritis after 16 Weeks of Golimumab Treatment

    Walter Maksymowych1, Sean P. Curtis2, Maxime Dougados3, Gina Bergman2, Susan Huyck2, Anjela Tzontcheva2 and Joachim Sieper4, 1Medicine, University of Alberta, Edmonton, AB, Canada, 2Merck & Co., Inc., Kenilworth, NJ, 3Paris-Descartes University, Paris, France, 4University Clinic Benjamin Franklin, Berlin, Germany

    Background/Purpose:  Chronic inflammation, back pain, and progressive spinal stiffness associated with axial spondyloarthritis (axSpA) can decrease quality of life (QoL). The purpose of this study…
  • Abstract Number: 709 • 2015 ACR/ARHP Annual Meeting

    Progression of Patients with Non-Radiographic Axial Spondyloarthritis to Ankylosing Spondylitis: A Population-Based Cohort Study

    Runsheng Wang1, Sherine Gabriel2 and Michael M. Ward1, 1NIH/NIAMS, Bethesda, MD, 2Division of Rheumatology; Department of Health Sciences Research, Mayo Clinic, Rochester, MN

    Background/Purpose: The long-term outcome of patients with non-radiographic axial spondyloarthritis (nr-axSpA) is unclear, particularly whether few or most progress to ankylosing spondylitis (AS).  Our objective…
  • Abstract Number: 713 • 2015 ACR/ARHP Annual Meeting

    Clinical and Imaging Efficacy of Etanercept in Early Non-Radiographic Axial Spondyloarthritis: 104-Week Treatment Results

    Maxime Dougados1, Désirée van der Heijde2, Joachim Sieper3, Juergen Braun4, Gustavo Citera5, Filip van Den Bosch6,7, Ronald Pedersen8, Randi Bonin9, Heather Jones10, Lisa Marshall10, Sameer Kotak11, Isabelle Logeart12, Bonnie Vlahos13, Jack F Bukowski9 and Walter Maksymowych14, 1Rheumatology Department, Hôpital Cochin, Paris, France, 2Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Medical Department I, Rheumatology, Charité Universitätesmedizin Berlin, Berlin, Germany, 4Rheumazentrum Ruhrgebiet, Herne, Germany, 5Rheumatology, Consultorios Reumatológicos Pampa, Buenos Aires, Argentina, 6Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, 7Rheumatology, Ghent University Hospital, Ghent, Belgium, 8Department of Biostatistics, Pfizer, Collegeville, PA, 9Clinical Affairs, Pfizer, Collegeville, PA, 10Inflammation Global Medical Affairs, Pfizer, Collegeville, PA, 11Global Health and Value, Pfizer, New York, NY, 12Medical Affairs, Pfizer, France, Paris, France, 13GIPB - Clinical Sciences, Pfizer, Collegeville, PA, 14Department of Medicine, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: In the multiphase, randomized, placebo (PBO)-controlled EMBARK study (ClinicalTrials.gov identifier: NCT01258738), clinical signs/symptoms and MRI-measured inflammation were evaluated in patients with early, active non-radiographic…
  • Abstract Number: 714 • 2015 ACR/ARHP Annual Meeting

    Baseline MRI and CRP As Predictors of Response to Etanercept in the Management of Patients with Non-Radiographic Axial Spondyloarthritis (nr-axSpA)

    Matthew A. Brown1, Paul A. Bird2, Philip C. Robinson3, Philip J. Mease4, Filip van Den Bosch5, Christine Surian6, Zirke Wiid6, Heather Jones7, Annette Szumski8 and Lisa Marshall7, 1Translational Research Institute, University of Queensland Diamantina Institute, Brisbane, Australia, 2University of New South Wales, Sydney, Australia, 3University of Queensland & Royal Brisbane and Women's Hospital, Brisbane, Australia, 4Rheumatology Research, Swedish Medical Center, Seattle, WA, 5Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, 6Pfizer Australia, Sydney, Australia, 7Inflammation Global Medical Affairs, Pfizer, Collegeville, PA, 8Department of Biostatistics, Pfizer, Collegeville, PA

    Background/Purpose: Treatment with tumor necrosis factor α (TNFα) inhibitors has been shown to be effective in improving disease activity and functional capacity in patients with…
  • Abstract Number: 976 • 2015 ACR/ARHP Annual Meeting

    The Reason of Discontinuation of a First TNF Inhibitor Affects Drug Retention of a Second Anti-TNF Agent in Axial Spondyloarthritis

    Adrian Ciurea1, Pascale Exer2, Ulrich Weber3,4, Giorgio Tamborrini5, Beate Steininger1, Rudolf O. Kissling6, Jürg Bernhard7 and Almut Scherer8, 1Rheumatology, University Hospital Zurich, Zurich, Switzerland, 2Private rheumatology practice, Basel, Switzerland, 3Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark, 4Department of Research, King Christian 10th Hospital for Rheumatic Diseases, Graasten, Denmark, 5Department of Rheumatology, University Hospital, Zurich, Switzerland, 6Division of Rheumatology, Balgrist University Hospital, Zurich, Switzerland, 7Rheumatology and Rehabilitation, Bürgerspital Solothurn, Solothurn, Switzerland, 8SCQM Foundation, Zurich, Switzerland

    Background/Purpose: Conflicting results have been demonstrated in axial spondyloarthritis (axSpA) with regard to whether effectiveness of a second (2°) TNFi depends on the reason of…
  • Abstract Number: 1231 • 2015 ACR/ARHP Annual Meeting

    The Prevalence of Non-Radiographic Axial Spondyloarthritis Among Patients with Inflammatory Back Pain in Rheumatology Practices

    Rubén Burgos-Vargas1, James Wei2, Mahboob U Rahman3, Nurullah Akkoc4, Syed A. Haq5, Mohammed Hammoudeh6, Ehab Mahgoub7, Ena Singh8, Lyndon Llamado9, Khalid Shirazy10, Sameer Kotak11, Connie Hammond7, Ronald Pedersen12, Qi Shen13 and Bonnie Vlahos13, 1Rheumatology, Hospital General de Mexico, Mexico city, Mexico, 2Division of Allergy, Immunology and Rheumatology, Chung Shan Medical University Hospital, Taichung, Taiwan, 3Perelman School of Medicine, University of Pennsylvania, Philadephia, PA, 4Department of Rheumatology, Dokuz Eylul University, Faculty of Medicine, Izmir, Turkey, 5Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, 6Medicine, Hamad Medical Corporation, Doha, Qatar, 7Pfizer, Collegeville, PA, 8500 Arcola Road, Pfizer, Collegeville, PA, 9Pfizer, Makati, Philippines, 10Pfizer, Dubai, United Arab Emirates, 11Global Health and Value, Pfizer, New York, NY, 12Department of Biostatistics, Pfizer, Collegeville, PA, 13GIPB - Clinical Sciences, Pfizer, Collegeville, PA

    Background/Purpose: The diagnosis of Ankylosing Spondylitis (AS) is delayed by >10 years after the symptoms develop, as by definition the modified NY criteria for classification…
  • Abstract Number: 1283 • 2015 ACR/ARHP Annual Meeting

    The Burden of Non-Radiographic Axial Spondyloarthritis from the Employer Perspective: A Real World European Study

    Tim Holbrook1, Robert Wood1, Christopher Black2, Xiaohan Hu2 and Sumesh Kachroo2, 1Adelphi Real World, Macclesfield, United Kingdom, 2CORE, Merck & Co., Inc., Rahway, NJ

    Background/Purpose: Non-radiographic axial spondyloarthritis (nr-axSpA) is a burdensome disease to both the patient and the healthcare system, as previous research has indicated. However, the societal…
  • Abstract Number: 1284 • 2015 ACR/ARHP Annual Meeting

    Burden of Illness Associated with Non-Radiographic Axial Spondyloarthritis: A European Real World Database Analysis from the Clinical and Healthcare System Perspective

    Tim Holbrook1, Robert Wood1, Christopher Black2, Xiaohan Hu2 and Sumesh Kachroo2, 1Adelphi Real World, Macclesfield, United Kingdom, 2CORE, Merck & Co., Inc., Rahway, NJ

    Background/Purpose: Whilst the burden of axial spondyloarthritis (axSpA) is well known, non-radiographic (nr)-axSpa has only recently been identified as a distinct spondyloarthritic indication with its…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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