Abstracts tagged "axial spondyloarthritis"

Abstract Number: 706 • 2016 ACR/ARHP Annual Meeting
Performance of the ASAS Classification Criteria for Axial and Peripheral Spondyloarthritis – a Systematic Literature Review and Meta-Analysis
Alexandre Sepriano¹, Roxana Rubio¹, Sofia Ramiro¹, Robert Landewé² and Désirée van der Heijde³, ¹Leiden University Medical Center, Leiden, Netherlands, ²Amsterdam Rheumatology & Immunology Center, Amsterdam, Netherlands, ³Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: The Assessment of SpondyloArthritis international Society (ASAS) has developed and validated classification criteria for axial spondyloarthritis (axSpA) and peripheral SpA (pSpA). Following their release,…
Abstract Number: 3010 • 2016 ACR/ARHP Annual Meeting
Improvement of Spinal Inflammation Induced By Etanercept in Enthesitis Related Arthritis JIA-Patients. Data of the Reminder-Study
Gerd Horneff¹, Ivan Foeldvari², Kirsten Minden^3,4, Hans-Iko Huppertz⁵ and Ariane Klein⁶, ¹Department of Pediatrics, Centre of Pediatric Rheumatology, Sankt Augustin, Germany, ²Kinder- und Jugenrheumatologie, Hamburger Zentrum Kinder-und Jugendrheumatologie, Hamburg, Germany, ³Epidemiology, Charite, DRFZ, Berlin, Germany, ⁴Children’s University Hospital Charite/German Rheumatism Research Centre Berlin, Berlin, Germany, ⁵Klinikum Bremen-Mitte, Prof.-Hess-Kinderklinik, Bremen, Germany, ⁶Center of Pediatrics and Neonatology, Asklepios Clinic Sankt Augustin, Sankt Augustin, Germany
Background/Purpose: The data of the REMINDER study, a two-part, 48-week, randomized, placebo-controlled, double-blind withdrawal study on efficacy of etanercept (ETA) compared to placebo (PLC) in…
Abstract Number: 1283 • 2015 ACR/ARHP Annual Meeting
The Burden of Non-Radiographic Axial Spondyloarthritis from the Employer Perspective: A Real World European Study
Tim Holbrook¹, Robert Wood¹, Christopher Black², Xiaohan Hu² and Sumesh Kachroo², ¹Adelphi Real World, Macclesfield, United Kingdom, ²CORE, Merck & Co., Inc., Rahway, NJ
Background/Purpose: Non-radiographic axial spondyloarthritis (nr-axSpA) is a burdensome disease to both the patient and the healthcare system, as previous research has indicated. However, the societal…
Abstract Number: 1284 • 2015 ACR/ARHP Annual Meeting
Burden of Illness Associated with Non-Radiographic Axial Spondyloarthritis: A European Real World Database Analysis from the Clinical and Healthcare System Perspective
Tim Holbrook¹, Robert Wood¹, Christopher Black², Xiaohan Hu² and Sumesh Kachroo², ¹Adelphi Real World, Macclesfield, United Kingdom, ²CORE, Merck & Co., Inc., Rahway, NJ
Background/Purpose: Whilst the burden of axial spondyloarthritis (axSpA) is well known, non-radiographic (nr)-axSpa has only recently been identified as a distinct spondyloarthritic indication with its…
Abstract Number: 2025 • 2015 ACR/ARHP Annual Meeting
Modification of Structural Lesions on Magnetic Resonance Imaging By Etanercept: A 12-Week Randomized Placebo-Controlled Trial
Walter Maksymowych¹, Stephanie Wichuk², Maxime Dougados³, Heather Jones⁴, Annette Szumski⁵, Lisa Marshall⁴, Jack F Bukowski⁶ and Robert G Lambert⁷, ¹Department of Medicine, University of Alberta, Edmonton, AB, Canada, ²Rheumatology Research Lab, University of Alberta, Edmonton, AB, Canada, ³Rheumatology Department, Hôpital Cochin, Paris, France, ⁴Inflammation Global Medical Affairs, Pfizer, Collegeville, PA, ⁵Department of Biostatistics, Pfizer, Collegeville, PA, ⁶Clinical Affairs, Pfizer, Collegeville, PA, ⁷Department of Radiology & Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Modification of structural lesions by anti-TNF therapy has not been demonstrated in a randomized placebo (PBO)-controlled trial. The Spondyloarthritis Research Consortium of Canada (SPARCC)…
Abstract Number: 2298 • 2015 ACR/ARHP Annual Meeting
Misdiagnosis of Fibromyalgia (FM) As Axial Spondylarthritis (SpA): Lessons from Analysis of 26 Cases
Dongfeng Liang, Jianglin Zhang and Feng Huang, Rheumatology, Chinese PLA General Hospital, Beijing, China
Background/Purpose: Both patients with fibromyalgia (FM) and with axial spondyloarthritis (SpA) are suffering from pain. The patients with axial SpA are mainly manifested as inflammatory…
Abstract Number: 2629 • 2015 ACR/ARHP Annual Meeting
The Most Frequent Fears and Beliefs of 226 Patients with Rheumatoid Arthritis or Spondyloarthritis, Using a Novel Questionnaire
Laure Gossec^1,2, Pierre Chauvin^3,4, Christophe Hudry⁵, Florence Mathoret-Philibert⁶, Maud Poussière⁷, Thibault de Chalus⁸, Francoise Russo-Marie⁹, Jean-Michel Joubert⁸, Alain Saraux¹⁰ and Francis Berenbaum^1,11, ¹Rheumatology Department, Sorbonne Universités, Université Pierre et Marie Curie, Paris, France, ²Rheumatology Department, AP-HP, Hôpital Pitié Salpêtrière, Paris, France, ³Department of Social Epidemiology, Sorbonne Universités, Université Pierre et Marie Curie, Paris, France, ⁴Department of Social Epidemiology, Pierre Louis Institute of Epidemiology and Public Health, Paris, France, ⁵Rheumatology, AP-HP, Hôpital Cochin, Paris, France, ⁶Clinical Psychology Department, AP-HP, Hôpital Cochin, Paris, France, ⁷Independent Researcher, Paris, France, ⁸UCB Pharma, Colombes, France, ⁹Arthritis Foundation Courtin, Neuilly-sur-Seine, France, ¹⁰Rheumatology Department, CHU de la Cavale Blanche, Brest Cedex, France, ¹¹Rheumatology Department, AP-HP, Hôpital Saint-Antoine, Paris, France
Background/Purpose: Patients with chronic inflammatory disorders such as rheumatoid arthritis (RA) or spondyloarthritis (SpA) create personal sets of fears and beliefs related to their disease.…
Abstract Number: 2632 • 2015 ACR/ARHP Annual Meeting
Development and Validation of a Questionnaire Assessing the Fears and Beliefs of Patients Suffering from Chronic Rheumatic Diseases
Laure Gossec^1,2, Alain Saraux³, Christophe Hudry⁴, Florence Mathoret-Philibert⁵, Maud Poussière⁶, Thibault de Chalus⁷, Francoise Russo-Marie⁸, Jean-Michel Joubert⁷, Pierre Chauvin⁹ and Francis Berenbaum^1,10, ¹Rheumatology Department, Sorbonne Universités, Université Pierre et Marie Curie, Paris, France, ²Rheumatology Department, AP-HP, Hôpital Pitié Salpêtrière, Paris, France, ³Rheumatology Department, CHU de la Cavale Blanche, Brest Cedex, France, ⁴Rheumatology, AP-HP, Hôpital Cochin, Paris, France, ⁵Clinical Psychology Department, AP-HP, Hôpital Cochin, Paris, France, ⁶Independent Researcher, Paris, France, ⁷UCB Pharma, Colombes, France, ⁸Arthritis Foundation Courtin, Neuilly-sur-Seine, France, ⁹Department of Social Epidemiology, Sorbonne Universités, Université Pierre et Marie Curie, Paris, France, ¹⁰Rheumatology Department, Hôpital Saint-Antoine, Paris, France
Background/Purpose: Questionnaires assessing the beliefs of patients with chronic rheumatic diseases mainly focus on medications.1A validated questionnaire evaluating patients' fears and beliefs towards their disease…
Abstract Number: 346 • 2015 ACR/ARHP Annual Meeting
Autoantibodies to Osteoprotegerin Are Independently Associated with Low Hip Bone Mineral Density and Increased Fractures in Axial Spondyloarthritis
Sizheng Zhao^1,2, Barbara Hauser³, Micaela Visconti³, Philip L. Riches³, Stuart H. Ralston³ and Nicola Goodson^1,2, ¹Musculoskeletal Biology I, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, United Kingdom, ²Department of Rheumatology, Aintree University Hospital, Liverpool, United Kingdom, ³Centre for Genomic and Experimental Medicine, Western General Hospital, Edinburgh, United Kingdom
Background/Purpose: Axial spondyloarthritis (axSpA) is associated with osteoporosis. However the underlying causes are incompletely understood. Osteoprotegerin (OPG) is a bone protective protein that acts as…
Abstract Number: 2812 • 2015 ACR/ARHP Annual Meeting
Cytokine Secretion By Peripheral Blood Mononuclear Cells in Patients with Axial Spondyloarthritis and the Effect of Thymoquinone on Cytokine Profile
Erkan Kilic¹, Cagri Sakalar², Huriye Aksu³, Mustafa Cakir³, Gamze Kilic¹ and Salih Ozgocmen⁴, ¹Dept. PRM, Erciyes University, Faculty of Medicine,Division of Rheumatology, Kayseri, Turkey, ²Genome and Stem Cell Center (GEN-KOK), Erciyes University, Faculty of Medicine, Medical Biology, Kayseri, Turkey, ³Genome and Stem Cell Senter (GEN-KOK), Erciyes University, Faculty of Medicine, Medical Biology, Kayseri, Turkey, ⁴Dept.PRM, Erciyes University, Faculty of Medicine,Division of Rheumatology, Kayseri, Turkey
Background/Purpose: Axial spondyloarthritis (axSpA) defines a group of chronic inflammatory diseases which includes non-radiographic axSpA (nr-axSpA) who do not have definite sacroiliitis on pelvic X-rays.…
Abstract Number: 663 • 2015 ACR/ARHP Annual Meeting
Mases Correlates Linearly with Disease Activity and Patient Related Outcomes in Patients with Axial Spondyloarthritis within the Scqm Cohort
Ruediger Mueller¹, Toni Kaegi², Nicole Graf³, Johannes von Kempis⁴ and J.J. Luime⁵, ¹Rheumatology, MD, St. Gallen, Switzerland, ²Kantonsspital St. Gallen, St. Gallen, Switzerland, ³graf biostatistics, Winterthur, Switzerland, ⁴Rheumatology, Kantonsspital St. Gallen, St. Gallen, Switzerland, ⁵Department of Rheumatology, Erasmus Medical Centre, Rotterdam, Netherlands
Background/Purpose: Enthesitis is one of the potential extra-axial manifestations found in patients with spondyloarthritis (SpA). Enthesitis can be quantified using the MASES (Maastrich Ankylosing Spondylitis…
Abstract Number: 2876 • 2015 ACR/ARHP Annual Meeting
Baseline Demographic and Disease Characteristics Associated with Response to Golimumab in Patients with Active Nonradiographic Axial Spondyloarthritis
Maxime Dougados¹, Gina Bergman², Walter Maksymowych³, Sean P. Curtis², Susan Huyck², Anjela Tzontcheva² and Joachim Sieper⁴, ¹Paris-Descartes University, Paris, France, ²Merck & Co., Inc., Kenilworth, NJ, ³University of Alberta, Edmonton, AB, Canada, ⁴University Clinic Benjamin Franklin, Berlin, Germany
Background/Purpose: Subgroup analyses can be used to investigate the size and direction of treatment effects across a range of demographic and disease characteristics. The purpose…
Abstract Number: 691 • 2015 ACR/ARHP Annual Meeting
Standards for the Classification of Non-Radiographic Axial Spondyloarthritis: A European Real World Study
Tim Holbrook¹, Robert Wood¹, Christopher Black², Xiaohan Hu² and Sumesh Kachroo², ¹Adelphi Real World, Macclesfield, United Kingdom, ²CORE, Merck & Co., Inc., Rahway, NJ
Background/Purpose: Classification of non-radiographic axial spondyloarthritis (nr-axSpA) requires the presence of Assessment of Spondyloarthritis international Society (ASAS) criteria for AxSpA, without radiologic evidence of sacroiliitis…
Abstract Number: 2878 • 2015 ACR/ARHP Annual Meeting
Treating Axial Spondyloarthritis to Target: Influence of the Population Characteristics and Comorbidities in Reaching Ankylosing Spondylitis Disease Activity Score (ASDAS) Inactive Disease in a Cohort of Patients Treated with Tnfalpha Inhibitors Agents
Sara Monti, Veronica Codullo, Vittorio Grosso, Silvia Breda, Carlomaurizio Montecucco and Roberto Caporali, Division of Rheumatology, University of Pavia, IRCCS Foundation Policlinico S. Matteo, Pavia, Italy
Background/Purpose: The treat to target strategy (T2T), aiming at inactive disease (ID), has become the recommended approach also in the field of axial-SpA (axSpA) (1). …
Abstract Number: 696 • 2015 ACR/ARHP Annual Meeting
Current and Past Smoking Are Associated with Functional Impairement and Increased Disease Activity in Axial Spondyloarthritis: Systematic Review and Meta-Analysis
Kristina SCHREIBER¹, Thomas Barnetche², BG Combe³, Jacques Morel¹ and Claire I. Daien¹, ¹Department of rheumatology, Lapeyronie Hospital and Montpellier University, Montpellier, France, ²Rheumatology Department, Pellegrin University Hospital, BORDEAUX, France, ³Lapeyronie, Montpellier, France
Background/Purpose: The influence of smoking on the development of rheumatoid arthritis, the severity of the disease and the response to treatment is well established. The…

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