Abstract Number: 1939 • 2019 ACR/ARP Annual Meeting
Analysis of Discoid Lupus Erythematosus (DLE) Gene Expression Reveals Dysregulation of Pathogenic Pathways Associated with Infiltrating Immune/Inflammatory Cells
Background/Purpose: DLE is a chronic, scarring inflammatory autoimmune disease of the skin. The precise molecular pathways underlying DLE pathogenesis have not been fully delineated. To…Abstract Number: 775 • 2019 ACR/ARP Annual Meeting
Cutaneous Gene Expression Signatures in Juvenile Myositis Reveal a Prominent IFN Signature in Lesional Skin
Background/Purpose: Skin inflammation can herald systemic disease manifestations and disease chronicity in juvenile myositis (JM), yet we lack an understanding of the pathogenic mechanisms driving…Abstract Number: 99 • 2018 ACR/ARHP Annual Meeting
DC-Hil+ Myeloid-Derived Suppressor Cells Are Elevated in the Peripheral Blood and Lesional Skin of Cutaneous Lupus Patients
Background/Purpose: Myeloid derived suppressor cells (MDSCs) are major T cell suppressors, and their dysfunction has been implicated in the pathophysiology of autoimmune diseases. MDSCs suppress…Abstract Number: 2040 • 2013 ACR/ARHP Annual Meeting
Pilot Study Of Abatacept In Patients With Refractory Autoimmune Chronic Urticaria
Background/Purpose: Associations between chronic urticaria (CU) with autoantibodies and other autoimmune conditions have implicated T cells in CU initiation and/or propagation. Many patients (pts) have…Abstract Number: 1935 • 2013 ACR/ARHP Annual Meeting
Validation Of The Cutaneous Dermatomyositis Disease Area and Severity Index: Characterizing Severity and Assessing Responsiveness To Clinical Change
Background/Purpose: Translational research and clinical trials necessitate validated outcome measures to reliably assess disease progression and treatment efficacy. The Cutaneous Dermatomyositis Disease Area and Severity…