ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstracts tagged "Autoantibody(ies)"

  • Abstract Number: L11 • ACR Convergence 2024

    Rheumatology Diagnostics Utilizing Artificial Intelligence (ANA Reader©) for ANA Pattern Identification and Titer Quantification

    May Choi1, Farbod Moghaddam1, Mohammad Sajadi1, Ann E. Clarke1, Sasha Bernatsky2, Karen Costenbader3, Irene Chen4, Murray Urowitz5, John Hanly6, Caroline Gordon7, Sang-Cheol Bae8, Juanita Romero-Diaz9, Jorge Sanchez-Guerrero10, Daniel Wallace11, David Isenberg12, Anisur Rahman13, Joan Merrill14, Paul Fortin15, Dafna Gladman16, Ian Bruce17, Michelle Petri18, Ellen Ginzler19, Mary Anne Dooley20, Rosalind Ramsey-Goldman21, Susan Manzi22, Andreas Jönsen23, Graciela Alarcón24, Ronald Van Vollenhoven25, Cynthia Aranow26, Meggan Mackay26, Guillermo Ruiz-Irastorza27, S. Sam Lim28, Murat Inanç29, Kenneth Kalunian30, Soren Jacobsen31, Christine Peschken32, Diane Kamen33, Anca Askanase34, Marvin Fritzler35 and Mina Aminghafari1, 1University of Calgary, Calgary, AB, Canada, 2Research Institute of the McGill University Health Centre, Montreal, QC, Canada, 3Brigham and Women's Hospital/Harvard Medical School, Boston, MA, 4UC Berkeley and UCSF, Berkeley, CA, 5Self employed, Toronto, ON, Canada, 6Dalhousie University, Halifax, NS, Canada, 7University of Birmingham, Birmingham, United Kingdom, 8Hanyang University Medical Center, Seoul, South Korea, 9The National Institute of Medical Sciences and Nutrition, Mexico City, Mexico, 10Krembil Research Institute, Toronto, ON, Canada, 11Cedars Sinai Medical Center, Studio City, CA, 12Department of Ageing, Rheumatology and Regenerative Medicine, Division of Medicine, University College London, London, United Kingdom, 13University College London, London, United Kingdom, 14Oklahoma Medical Research Foundation, Oklahoma City, OK, 15Centre ARThrite - CHU de Québec - UniversitéLaval, Quebec, QC, Canada, 16University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 17Queen's University Belfast, Belfast, United Kingdom, 18Johns Hopkins University School of Medicine, Baltimore, MD, 19SUNY Downstate Health Sciences University, New York, NY, 20UNC physician network, Chapel Hill, NC, 21Northwestern University, Chicago, IL, 22Allegheny Health Network, Pittsburgh, PA, 23Lund University, Lund, Sweden, 24The University of Alabama at Birmingham, Oakland, CA, 25Amsterdam UMC, Amsterdam, Netherlands, 26Feinstein Institutes for Medical Research, New York, NY, 27Biobizkaia Health Research Institute, Bilbao, Spain, 28Emory University, Atlanta, GA, 29Istanbul University, Istanbul, Turkey, 30UC San Diego, La Jolla, CA, 31Rigshospitalet, Copenhagen, Denmark, 32University of Manitoba, Winnipeg, MB, Canada, 33Medical University of South Carolina, Johns Island, SC, 34Columbia University Medical Center, New York, NY, 35Mitogen Diagnostics Corp, Calgary, AB, Canada

    Background/Purpose: Antinuclear antibody (ANA) immunofluorescence (IFA) patterns and titers are a key part of rheumatology diagnostics, however, there is considerable intra- and inter-laboratory variability with…
  • Abstract Number: 0009 • ACR Convergence 2024

    Comprehensive Autoantibody Profiling Highlights Clinical Relevance of Autoantibodies to G Protein-coupled Receptors in Systemic Sclerosis: Insights from a B-cell Depletion Clinical Trial

    Kazuki Matsuda, Shinichi Sato and Ayumi Yoshizaki, The University of Tokyo, Tokyo, Japan

    Background/Purpose: Systemic sclerosis (SSc) affects the skin and internal organs with a poor prognosis. While the exact cause remains unclear, increasing evidence indicates that B…
  • Abstract Number: 0308 • ACR Convergence 2024

    Interstitial Lung Disease as the First Clinical Manifestation of Connective Tissue Diseases

    Juan A. Meraz-Ostiz, Aina Puiggròs-Ferrer, Núria Bou, Irene Carrión-Barberà, Jordi Monfort, Carolina Pérez-García, Diana Badenes, Eva Balcells and Anna Pros-Simon, Hospital del Mar, Barcelona, Spain

    Background/Purpose: Interstitial lung disease (ILD) is a common complication of connective tissue diseases (CTDs), significantly influencing prognosis and mortality. The prevalence and characteristics of new…
  • Abstract Number: 0673 • ACR Convergence 2024

    BCMA-CD19 Compound CAR-T (cCAR) Safely Provides a Complete Humoral Reset Eliminating All Autoantibodies Resulting in Long-term Medication-Free Complete Remission Among Systemic Lupus Erythematosus (SLE) and Lupus Nephritis (LN) Patients

    Yong Yuan1, Shanzhi He2, Wenli Zhang3, Hongyu Zhang4, Vincent M DeStefano5, Masayuki Wada5, Kevin Pinz5, Greg Deener5, Yu Ma6, Min Wang2, Fugui Li7, Ming Hong1, Chanjuan Zou2, Mingxia Wang2, Ling Ding2, Yingwen Liang8, Yupo Ma5 and Weija Wang9, 1Department of Translational Medicine, Zhongshan people's Hospital, Zhongshan, China (People's Republic), 2Department of Rheumatoid Immunology, Zhongshan people's Hospital, Zhongshan, China (People's Republic), 3Department of Hematology, Peking University Shenzhen Hosptial, Shenzhen, China (People's Republic), 4Department of Hematology, Peking University Shenzhen Hospital, Shenzhen, China (People's Republic), 5iCell Gene Therapeutics, Inc., Stony Brook, NY, 6iCAR Bio Therapeutics Ltd, Zhongshan, China (People's Republic), 7Department of Translational Medicine. Zhongshan people's Hospital, Zhongshan, China (People's Republic), 8Department of Translational Medicine, Zhongshan's people Hospital, Zhongshan, China (People's Republic), 9Department of Translational Research, Zhongshan people's Hospital, Zhongshan, China (People's Republic)

    Background/Purpose: Medication free complete remission (CR) has been elusive in SLE. An open label investigator-initiated trial (IIT) infused SLE/LN patients with a novel cCAR targeting…
  • Abstract Number: 1161 • ACR Convergence 2024

    Characterization of the Clinical Presentation of Idiopathic Inflammatory Myopathies According to the Profile of Specific Autoantibodies with Multiple Positivity

    Adriana Miguel-Álvarez1, luis M Amezcua Guerra2, María L Loredo-Mendoza1, Luis H. Silveira Torre3 and Angélica Vargas Guerrero4, 1Instituto Nacional de Cardiología "Ignacio Chávez", México, Distrito Federal, Mexico, 2Department of Immunology, Instituto Nacional de Cardiología Ignacio Chávez., México, Mexico, 3Department of Rheumatology , Instituto Nacional de Cardiología Ignacio Chávez., Mexico City, Mexico, 4Department of Rheumatology , Instituto Nacional de Cardiología Ignacio Chávez., México, Mexico

    Background/Purpose: The aim of this study is to assess if there are clinical and serological differences in patients with idiopathic inflammatory myopathies (IIM) according to…
  • Abstract Number: 1589 • ACR Convergence 2024

    Whole Skin Gene Expression Analysis Identifies Discrete Modules That Differentiate Antinuclear Antibody Subsets in Systemic Sclerosis

    Kristina Clark1, Corrado Campochiaro2, Philip Yee3, Emma Derrett-Smith4, Voon Ong5 and Christopher Denton6, 1University of Oxford, Oxford, United Kingdom, 2IRCCS San Raffaele Hospital. Vita-Salute San Raffaele University, Milan, Milan, Italy, 3UCL, London, United Kingdom, 4University College London Division of Medicine, Birmingham, United Kingdom, 5University College London, London, England, United Kingdom, 6University College London, Northwood, United Kingdom

    Background/Purpose: Hallmark autoantibody reactivities predict different patterns of skin involvement and risk of internal organ involvement.  We have asked whether whole skin gene expression may…
  • Abstract Number: 1851 • ACR Convergence 2024

    Aberrant Tfh Cells Generated by Th17 Cell Plasticity in the Gut Promote Autoimmune Arthritis

    Joyce Wu, The Ohio State University, Columbus, OH

    Background/Purpose: Much remains unknown regarding T follicular helper 17 (Tfh17) cells in autoimmunity. We previously showed, and here ask why, egress of gut segmented filamentous…
  • Abstract Number: 2305 • ACR Convergence 2024

    Anti-Ku Positivity in Primary Sjögren’s Disease Is Associated with a More Systemic Active Disease

    Marie ROBERT1, Yann Nguyen2, Yurdagül Uzunhan3, Benjamin Terrier4, Yves Allenbach5, Alain Meyer6, Jacques-Eric Gottenberg7, JEROME HADJADJ8, Zahir Amoura9, ARNAUD HOT10, Eléonore Bettacchioli11, Elisabeth Aslangul12, Rakiba Belkhir13, Frederic Desmoulins14, Elisabeth Bergé14, Pascale Chrétien15, Pascale Roland-Nicaise16, Claire Goulvestre17, Jean-Luc Charuel18, Benoit Nespola19, Nicole Fabien20, Eric Ballot21, Gaetane Nocturne14, Xavier Mariette14, Samuel Bitoun1 and Raphaele Seror22, 1Service de Rhumatologie, Hôpital Bicêtre, AP-HP, Le Kremlin-Bicetre, France, 2Université Paris Saclay, Clichy, Ile-de-France, France, 3Service de Pneumologie, Hôpital Avicenne, AP-HP, Bobigny, France, 4Service de Médecine interne, Hôpital Cochin, AP-HP, Paris, Ile-de-France, France, 5Service de Médecine interne et immunologie clinique, Hôpital Pitié-Salpêtrière, AP-HP, Paris, France, 6UR3072, Physiology Department, Rheumatology Department, University Hospital of Strasbourg, Strasbourg, France, 7Rheumatology Department, Strasbourg University Hospital,, Strasbourg, France, 8Service de Médecine interne, Hôpital Saint-Antoine, AP-HP, Paris, Ile-de-France, France, 9French National Reference Centre for Systemic Lupus Erythematosus, Pitié-Salpêtrière Hospital, Paris, France, 10Service de Médecine interne, Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France, 11Service de Rhumatologie, CHU de Brest, Brest, France, 12Service de Médecine interne, Hôpital Louis Mourier, AP-HP, Colombes, France, 13Service de Rhumatologie, Hôpital Bicêtre, AP-HP, Le Kremlin-Bicêtre, France, 14Service de Rhumatologie, Hôpital Bicêtre, AP-HP, Le Kremlin Bicetre, France, 15Laboratoire d'immunologie, Hôpital Bicêtre, AP-HP, le Kremlin Bicetre, France, 16Laboratoire d'immunologie, Hôpital Bichat, AP-HP, Paris, France, 17Laboratoire d'immunologie, Hôpital Cochin, AP-HP, Paris, Ile-de-France, France, 18Laboratoire d'immunologie, Hôpital Pitié-Salpêtrière, AP-HP, Paris, France, 19Laboratoire d’immunologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, 20Laboratoire d'immunologie, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Pierre Bénite, France, 21Laboratoire d'immunologie, Hôpital Saint-Antoine, AP-HP, Paris, Ile-de-France, France, 22Service de Rhumatologie, Hôpital Bicêtre, AP-HP, le Kremlin Bicetre, Ile-de-France, France

    Background/Purpose: Sjögren’s disease (SjD) is an autoimmune disease characterized by a wide range of symptoms, and 30% to 60% of patients developed systemic manifestations. The…
  • Abstract Number: 0013 • ACR Convergence 2024

    Preclinical Polypharmacology of S-1117, a Novel Engineered Fc-fused IgG Degrading Enzyme, for Chronic Treatment of Autoantibody-mediated Diseases

    Julia Manasson1, Liliana Sanmarco2, Alex Pellerin2, Jordan Anderson2, Nathan Rollins2, Tobias Green2, Agustin Plasencia2, Andita Newton2, Ryan Peckner2, Yi Xing2, Heather Vital3, Nathan Higginson-Scott2, John Sundy4, Kevin L. Otipoby2 and Ivan Mascanfroni2, 1Seismic Therapeutic, New York, NY, 2Seismic Therapeutic, Watertown, MA, 3Seismic Therapeutic, Lexington, MA, 4Seismic Therapeutic, Chapel Hill, NC

    Background/Purpose: Pathogenic autoantibodies are key effectors of inflammation, promoting immune cell responses that cause tissue damage in autoantibody-mediated diseases such as idiopathic inflammatory myopathies, lupus…
  • Abstract Number: 0319 • ACR Convergence 2024

    Sporadic Inclusion Body Myositis Novel Autoantibody and Biomarker Research Utilizing Proteome Microarray and Mass Spectrometry Proteomics Analysis

    Farbod Moghaddam1, Mark Tarnopolsky2, Valérie Leclair3, marie Hudson3, Ross Mitchell4, Katherine Buhler1, Erin Hatcher5, Meifeng Zhang1, Antoine Dufour1, Luiz de Almeida1, Marvin Fritzler6 and May Choi1, 1University of Calgary, Calgary, AB, Canada, 2McMaster University, Hamilton, ON, Canada, 3McGill University, Montreal, QC, Canada, 4University of Alberta, Edmonton, Canada, 5McMaster University, Hamilton, Canada, 6Mitogen Diagnostics Corp, Calgary, AB, Canada

    Background/Purpose: Sporadic inclusion body myositis (sIBM) is often challenging to diagnose because many patients have no known biomarkers (seronegative). Machine learning was applied to identify…
  • Abstract Number: 0697 • ACR Convergence 2024

    Association of ANCA-Associated Vasculitis and Development of SSc and SSc-Associated Antibodies: Impact of Pulmonary Arterial Hypertension

    Brett Dinner1, Ahmed Abdelmaksoud2, Ann Igoe3, Taylor Viggiano4 and Vivek Nagaraja5, 1Creighton University, Paradise Valley, AZ, 2University of California, Riverside, Riverside, CA, 3Flow, Tempe, AZ, 4Mayo Clinic, Phoenix, 5Mayo Clinic Arizona, Scottsdale, AZ

    Background/Purpose: Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is a spectrum of autoimmune disorders characterized by necrotizing small-to-medium vessel inflammation and circulating ANCAs. Represented by granulomatosis…
  • Abstract Number: 1164 • ACR Convergence 2024

    IVIG Treatment Duration in Immune-mediated Necrotizing Myopathy and a Possible Association of Vacuolar Changes with Black/African American Female Patients

    Asim Mohamed1, Liron Caplan2 and Melissa Griffith3, 1PGY5, Aurora, CO, 2Rocky Mountain Regional VAMC, Aurora, CO, 3University of Colorado, Aurora, CO

    Background/Purpose: Immune Mediated Necrotizing Myopathy (IMNM) is a debilitating but understudied entity.  Correlations of demographic and clinical features with pathological findings remain underexplored.  In addition,…
  • Abstract Number: 1603 • ACR Convergence 2024

    Antineutrophil Cytoplasmic Autoantibody Levels in Patients in the Avacopan Phase 3 Trial

    Frank B. Cortazar1, Duvuru Geetha2, Salem Almaani3, Christina Song4, Tomasz M. Wilmanski4, Alana M. Bozeman4, Peter Merkel5 and David Jayne6, and ADVOCATE Study Group, 1New York Nephrology Vasculitis and Glomerular Center, Saint Peter’s Hospital-Albany, Albany, NY, 2Johns Hopkins University, Baltimore, MD, 3The Ohio State University Medical Center, Columbus, OH, 4Amgen Inc., Thousand Oaks, CA, 5University of Pennsylvania, Philadelphia, PA, 6University of Cambridge, Cambridge, United Kingdom

    Background/Purpose: The utility of measuring serial antineutrophil cytoplasmic autoantibody (ANCA) levels to guide treatment in granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) is controversial.…
  • Abstract Number: 1858 • ACR Convergence 2024

    Co-modification of Citrullinated Proteins with Malondialdehyde-Acetaldehyde Leads to Amplified T Cell Responses and Increased Disease-specific Autoantibody Concentrations

    Breanna Butler1, Wenxian Zhou2, Michael Duryee1, Nozima Aripova1, Engle Sharp1, Carlos Hunter1, Bridget Kramer1, Harlan Sayles1, James O'Dell1, Geoffrey Thiele1, Bryant England1, Joshua Baker3, Andreas Reimold4, Gail Kerr5 and Ted Mikuls1, 1University of Nebraska Medical Center, Omaha, NE, 2University of Nebraska Medical Center, Bellevue, NE, 3University of Pennsylvania, Philadelphia, PA, 4Dallas VA Medical Center, Dallas, TX, 5Washington DC VAMC/Georgetown and Howard Universities, Washington, DC

    Background/Purpose: Anti-citrullinated protein antibody (ACPA) is highly specific to rheumatoid arthritis (RA). Beyond citrullination, other post-translational protein modifications including malondialdehyde-acetaldehyde (MAA) are targeted by T…
  • Abstract Number: 2315 • ACR Convergence 2024

    Exploring Antibodies in Psoriatic Arthritis: A Novel Autoimmune Biomarker Discovered

    Theo WIRTH1, Emmanuel Massy2, Nathalie Lambert3, Isabelle Auger3, Nathalie Balandraud1 and Florent Amatore4, 1Department of Rheumatology, Sainte Marguerite Hospital, Assistance Publique des Hôpitaux de Marseille, Aix Marseille University, Marseille, France, 2Department of Rheumatology, Lyon Sud Hospital, Hospices Civils de Lyon, Lyon, France, 3INSERM UMRs1097, Arthrites autoimmunes, Marseille, Marseille, France, 4Department of Dermatology, Nord hospital, Assistance Publique des Hôpitaux de Marseille, Aix Marseille University, MARSEILLE 9EME, France

    Background/Purpose: Psoriatic arthritis (PsA) can be challenging to diagnose due to the lack of specific biomarkers. Although a few teams have demonstrated the presence of…
  • 1
  • 2
  • 3
  • …
  • 29
  • Next Page »
Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

ACR Abstract Embargo Policy

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying financial and other sponsors about this policy. If you have questions about the abstract embargo policy, please contact the public relations department at [email protected].

Copyright Policy

View ACR Policies.

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2025 American College of Rheumatology