ACR Meeting Abstracts

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Abstracts tagged "Arthritis"

  • Abstract Number: 2084 • 2015 ACR/ARHP Annual Meeting

    Dendritic Cell-Specific Transmembrane Protein (DC-STAMP) Modulates Bone Resorption in Inflammatory Arthritis and Fracture Repair

    Yahui Grace Chiu1, Tzong-Ren Sheu2, Jinbo Li3, Dongge Li4, Michael Thullen2, Brendan Boyce5, Christopher T. Ritchlin6 and Javier Rangel-Moreno7, 1Allergy, Immunology, and Rheumatology, University of Rochester, Rochester, NY, 2Center for Musculoskeletal Research, University of Rochester, Rochester, NY, 3Pathology, University of Rochester, Rochester, NY, 4Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, 5University of Rochester, Rochester, NY, 6Allergy, Immunology and Rheumatololgy Division, University of Rochester Medical Center, Rochester, NY, 7Allergy, Immunology & Rheumatology, University of Rochester, Rochester, NY

    Background/Purpose: Osteoclasts (OC) direct pathologic bone resorption in osteoporosis and inflammatory arthritis. We previously demonstrated that DC-STAMP (Dendritic Cell-Specific Transmembrane protein), a 7-pass transmembrane protein,…
  • Abstract Number: 1167 • 2015 ACR/ARHP Annual Meeting

    Treating Experimental Arthritis with Adenoviral Overexpression of IL-22 or with Blocking Antibodies Against Endogenous IL-22 Both Reduces Inflammation and Destruction

    Marije I. Koenders1, Debbie M. Roeleveld1, Loreto Parga1, Shahla Abdolahi-Roodsaz1, Fons A.J. van de Loo1, Jay K. Kolls2 and Peter M. van der Kraan1, 1Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, 2Richard King Mellon Foundation Institute for Pediatric Research, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA

    Background/Purpose: Interleukin-22 (IL-22) is an IL-10 family cytokine member that was recently discovered to be mainly produced by Th17 cells. Previous studies have indicated the…
  • Abstract Number: 2090 • 2015 ACR/ARHP Annual Meeting

    Gender-Specific Pathways Linking Arthritis, Activity Limitation and Incident Heart Disease: A Causal Mediation Analysis of the Canadian Longitudinal National Population Health Survey

    Orit Schieir1, Sheilah. Hogg-Johnson1,2, Richard H Glazier3,4,5,6 and Elizabeth M. Badley1,7, 1Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, 2Institute for Work and Health, Toronto, ON, Canada, 3Family and Community Medicine, St. Michael's Hospital, Toronto, ON, Canada, 4Centre for Research on Inner City Health, St. Michael's Hospital, Toronto, ON, Canada, 5Family and Community Medicine, University of Toronto, Toronto, ON, Canada, 6Institute for Clinical Evaluative Sciences, Toronto, ON, Canada, 7Division of Health Care and Outcomes Research, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada

    Background/Purpose: Arthritis and activity limitation are risk factors for cardiovascular (CVD) morbidity and mortality. As arthritis is a major cause of activity limitation, the objective…
  • Abstract Number: 1206 • 2015 ACR/ARHP Annual Meeting

    Presence of ACPA in a Large (>40.000) Population Based Cohort from the Netherlands

    Elisabeth Brouwer1, Suzanne Arends2, Hendrika Bootsma1, Caroline Roozendaal3, Pieter C Limburg4, Fiona Maas1, René E. M. Toes5, T. W. J. Huizinga6, LA Trouw7 and Annemirthe Van Zanten1, 1Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, 2Rheumatology, Medical Center Leeuwarden, Leeuwarden, Netherlands, 3Laboratory Medicine, University Medical Center Groningen, Groningen, Netherlands, 4Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, 5Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 6Leiden University Medical Center, Leiden, Netherlands, 7Rheumatology, Leiden University Medical Centre, Leiden, Netherlands

    Background/Purpose: Anti-citrullinated protein antibodies (ACPA) status provides important information regarding the diagnosis and prognosis of Rheumatoid Arthritis (RA). By using samples from blood bank donors…
  • Abstract Number: 2111 • 2015 ACR/ARHP Annual Meeting

    A Study to Evaluate the Efficacy and Safety of Arhalofenate for Preventing Flares and Reducing Serum Uric Acid in Gout Patients

    Alexandra Steinberg1, Harinder Chera1, Yun-Jung Choi1, Robert Martin1, Charles McWherter1, Yunbin Zhang2, Pol Boudes1 and on behalf of the Arhalofenate Anti-Flare Therapy Study Group, 1Cymabay Therapeutics, Newark, CA, 2INC Research, Raleigh, NC

    Background/Purpose: Arhalofenate is a novel Urate-Lowering Anti-Flare Therapy (ULAFT) to treat gout.  It lowers serum uric acid (sUA) by blocking URAT1, a tubular UA transporter, and…
  • Abstract Number: 1244 • 2015 ACR/ARHP Annual Meeting

    Extracellular MicroRNAs in Synovial Fluid Reveal a Marked Proliferative Signature in Patients with Antibiotic-Refractory Lyme Arthritis

    Robert B. Lochhead, Nancy D. Kim, Sheila Arvikar, Klemen Strle and Allen C. Steere, Division of Rheumatology, Allergy & Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Lyme arthritis (LA), caused by a tick-borne spirochete Borrelia burgdorferi, usually resolves appropriately with antibiotic treatment, called antibiotic-responsive LA. However, in some patients, arthritis…
  • Abstract Number: 2162 • 2015 ACR/ARHP Annual Meeting

    Associations Between Education and Health Status Among Hispanics with Self-Reported Arthritis and/or Joint Pain

    Leigha Vilen1, Rebecca J. Cleveland2, Alfredo Rivadeneira1, Mary Altpeter3, Betsy Hackney4, Victoria Sepulveda2 and Leigh F. Callahan4, 1Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, 2University of North Carolina at Chapel Hill, Chapel Hill, NC, 3Institute on Aging, University of North Carolina at Chapel Hill, Chapel Hill, NC, 4Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC

    Background/Purpose: Understanding the associations between education and health status among Hispanics with arthritis and/or joint pain is crucial in adapting existing arthritis interventions for this…
  • Abstract Number: 1345 • 2015 ACR/ARHP Annual Meeting

    The Impact of Prior Antibiotic Treatment on Culture Results of Patients with Septic Arthritis

    Ziv Paz1, Sarah B. Lieber1, Andrew Moore2, Clara Zhu3, Mary Louise Fowler4 and Robert H. Shmerling5, 1Beth Israel Deaconess Medical Center, Boston, MA, 2Medicine, Cambridge Health Alliance, Harvard Medical School, Cambridge, MA, 3Medical School, Boston University School of Medicine, Boston, MA, 4School of Medicine, Boston University School of Medicine, Boston, MA, 5Medicine, Beth Israel Deaconess Medical Center, Boston, MA

    Background/Purpose: Synovial fluid culture and gram stain offer the most compelling proof of septic arthritis (SA); these tests are indicated in every suspected case. However,…
  • Abstract Number: 2259 • 2015 ACR/ARHP Annual Meeting

    Incidence of Obesity, Diabetes and High Blood Pressure Associated with Arthritis: Analysis of the Canadian Longitudinal National Population Health Survey

    Orit Schieir1, Sheilah. Hogg-Johnson1,2, Richard H Glazier3,4,5,6 and Elizabeth M. Badley1,7, 1Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, 2Institute for Work and Health, Toronto, ON, Canada, 3Family and Community Medicine, St. Michael's Hospital, Toronto, ON, Canada, 4Centre for Research on Inner City Health, St. Michael's Hospital, Toronto, ON, Canada, 5Institute for Clinical Evaluative Sciences, Toronto, ON, Canada, 6Family and Community Medicine, University of Toronto, Toronto, ON, Canada, 7Health Care & Outcomes Research, Toronto Western Res. Institute, Toronto, ON, Canada

    Background/Purpose: While cross-sectional evidence points to a higher prevalence of cardiovascular (CVD) risk factors in persons with arthritis, longitudinal population based studies are lacking. The…
  • Abstract Number: 1346 • 2015 ACR/ARHP Annual Meeting

    The Presentation and Outcomes of Surgically Treated Septic Arthritis:  the Impact of Culture Results

    Ziv Paz1, Mary Louise Fowler2, Clara Zhu3, Sarah B. Lieber1, Andrew Moore4 and Robert H. Shmerling5, 1Beth Israel Deaconess Medical Center, Boston, MA, 2School of Medicine, Boston University School of Medicine, Boston, MA, 3Medical School, Boston University School of Medicine, Boston, MA, 4Medicine, Cambridge Health Alliance, Harvard Medical School, Cambridge, MA, 5Medicine, Beth Israel Deaconess Medical Center, Boston, MA

    Background/Purpose: Clinically-suspected septic arthritis is culture-negative in 18-43% of cases.  These patients are often treated surgically with associated morbidity, prolonged hospital stays and high medical…
  • Abstract Number: 2283 • 2015 ACR/ARHP Annual Meeting

    Current and Lifetime Smoking Among US Adults with Arthritis: A Serious Clinical and Public Health Issue

    Louise Murphy1, Miriam G. Cisternas2 and Teresa J. Brady1, 1Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA, 2MGC Data Services, Carlsbad, CA

    Background/Purpose: Smoking's adverse effects include increased risk of joint replacement failure and decreased medication effectiveness (e.g., methotrexate, TNF blockers).  Because little is known about the…
  • Abstract Number: 1347 • 2015 ACR/ARHP Annual Meeting

    The Presentations and Outcomes of Prosthetic Joint Septic Arthritis:  a Comparison of Culture-Positive and Culture-Negative Disease

    Ziv Paz1, Sarah B. Lieber1, Andrew Moore2, Clara Zhu3, Robert H. Shmerling4 and Mary Louise Fowler5, 1Beth Israel Deaconess Medical Center, Boston, MA, 2Medicine, Cambridge Health Alliance, Harvard Medical School, Cambridge, MA, 3Medical School, Boston University School of Medicine, Boston, MA, 4Medicine, Beth Israel Deaconess Medical Center, Boston, MA, 5School of Medicine, Boston University School of Medicine, Boston, MA

    Background/Purpose: Prosthetic joint septic arthritis (PJSA) may complicate joint replacement in approximately 1-2% of cases. Synovial fluid cultures are negative in up to 25% of…
  • Abstract Number: 2372 • 2015 ACR/ARHP Annual Meeting

    Timing of Onset and Cluster with Other Manifestations Influence the Spectrum of Arthritis in Anti Jo-1 Positive Antisynthetase Syndrome: Results from a Multicenter, International, Retrospective Study

    Alberto Sifuentes Giraldo1, Carlo Alberto Scirè2, Santos Castañeda3, Laura Nuño4, Francisco Javier Lopez Longo5, Julia Martínez-Barrio5, Franco Franceschini6, Ilaria Cavazzana6, Paolo Airò7, Elena Bartoloni Bocci8, Javier Bachiller Corral9, Rossella Neri10, Simone Barsotti11, Roberto Caporali12, Carlomaurizio Montecucco13, Marcello Govoni14, Renato La Corte14, Federica Furini14, Florenzo Iannone15, Margherita Giannini16, Enrico Fusaro17, Simone Parisi18, Giuseppe Paolazzi19, Giovanni Barausse19, Raffaele Pellerito20, Alessandra Russo20, Lesley Ann Saketkoo21, Norberto Ortego-Centeno22, Luca Quartuccio23, Christof Specker24, Andreas Schwarting25, Kostantinos Triantafyllias26, Carlo Selmi27, Fausto Salaffi28, Marco Amedeo Cimmino29, Annamaria Iuliano30, Fabrizio Conti31, Gianluigi Baiocchi32, Elena Bravi33, Veronica Codullo12, Anna Ghirardello34, Trinitario Pina35, Miguel Angel Gonzalez-Gay35, Lorenzo Cavagna13 and AENEAS (American and European NEtwork of Antisynthetase Syndrome) collaborative group, 1Department of Rheumatology, University Hospital Ramón y Cajal, Madrid, Spain, 2Epidemiology Unit – Italian Society for Rheumatology (SIR), Milano, Italy, 3Rheumatology, H.U. La Princesa, Madrid, Spain, 4Servicio de Reumatologia, Hospital Universitario La Paz, Madrid, Spain, 5Servicio de Reumatologia, Hospital General Universitario Gregorio Marañón, Madrid, Spain, 6Rheumatology and Clinical Immunology, Spedali Civili and University of Brescia, Brescia, Italy, 7Rheumatology Unit, Spedali Civili of Brescia, Brescia, Italy, 8Rheumatology Unit, Department of Clinical & Experimental Medicine, University of Perugia, Perugia, Italy, 9Rheumatology, University Hospital Ramón y Cajal, Madrid, Spain, 10Rheumatology Unit, University of Pisa, Italy, Pisa, Italy, 11Division of Rheumatology, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy, 12Division of Rheumatology, University of Pavia, IRCCS Foundation Policlinico S. Matteo, Pavia, Italy, 13Division of Rheumatology, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy, 14UOC Reumatologia, Azienda Ospedaliera Universitaria S. Anna, Ferrara, Italy, 15Interdisciplinary Department of Medicine (DIM), Rheumatology Unit, University of Bari, Bari, Italy, 16DIM, Rheumatology Unit, Bari, Italy, 17Department of Rheumatology, Città della Salute e della Scienza, Torino, Italy, 18Department of Rheumatology, Città Della Salute e della Scienza, Torino, Italy, 19Rheumatology Unit, Santa Chiara Hospital, Trento, Italy, 20Division of Rheumatology, Mauriziano Hospital, Turin, Italy, 21Tulane University Lung Center, New Orleans Scleroderma and Sarcoidosis Patient Care and Research Center, New Orleans, LA, 22Systemic Autoimmune Diseases Unit, Hospital Universitario San Cecilio, Granada, Spain, 23Clinic of Rheumatology, Department of Medical and Biological Sciences (DSMB), Santa Maria della Misericordia Hospital, University of Udine, Udine, Italy, 24Department for Rheumatology and Clinical Immunology, St. Josef Krankenhaus, University Clinic, Essen, Germany, 25Department of Internal Medicine, Rheumatology and Clinical Immunology, University Hospital Johannes-Gutenberg, Mainz, Germany, 26ACURA Rheumatology Center, Bad Kreuznach, Germany, 27Internal Medicine- Unit of Rheumatology and Clinical Immunology, Humanitas Clinical and Research Center, Rozzano, Italy, 28Rheumatology Department, Polytechnic University of Marche, C. Urbani Hospital, Jesi,, Ancona, Italy, 29Research Laboratory and Academic Unit of Clinical Rheumatology, Department of Internal Medicine, University of Genoa, Genoa, Italy, 30Osp. San Camillo, Roma, Italy, 31Rheumatology Unit, Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, Italy, 32Rheumatology Unit, Department of Internal Medicine, S.Maria Hospital –IRCCS, Reggio Emilia, Italy, 33Internal Medicine, Rheumatology Unit, Ospedale Guglielmo da Saliceto, Piacenza, Italy, 34Department of Medicine-DIMED, University of Padova, Padova, Italy, 35Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain

    Background/Purpose: arthritis, myositis and interstitial lung disease (ILD) are reported in up to 90% of patients affected by antisynthetase syndrome (ASSD) and thus represent the…
  • Abstract Number: 2050 • 2014 ACR/ARHP Annual Meeting

    Knee Arthritis Is Positively Associated with Physical Impairment: Conclusion Based on Physical Examinations from a Cross-Sectional Study of 17708 Chinese Residents

    Qiang Liu1, Xu Tang Sr.2, Xu Wu3, Zhengming Cao2 and Jianhao Lin2, 1Arthritis Clinical and Reserch Center, Peking University People's Hospital, Peking University Health Science Center, Beijing, China, 2Peking University Health Science Center, Beijing, China, 3Peking University People's Hospital Arthritis Clinic & Research Center, Peking University Health Science Center, Beijing, China

    Background/Purpose The prevalence of knee arthritis is high in both urban and rural China. Although the association between knee arthritis and limitation of daily activity…
  • Abstract Number: 67 • 2014 ACR/ARHP Annual Meeting

    Effects of Exercise on Depressive Symptoms in Adults with Arthritis: A Systematic Review with Meta-Analysis

    George A. Kelley1, Kristi S. Kelley1 and Jennifer Hootman2, 1Biostatistics, West Virginia University, Morgantown, WV, 2Population Health, Centers for Disease Control and Prevention, Atlanta, GA

    Background/Purpose: Previous randomized controlled trials have led to conflicting findings regarding the effects of exercise on depressive symptoms in adults with arthritis and other rheumatic…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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