Abstract Number: 2084 • 2015 ACR/ARHP Annual Meeting
Dendritic Cell-Specific Transmembrane Protein (DC-STAMP) Modulates Bone Resorption in Inflammatory Arthritis and Fracture Repair
Background/Purpose: Osteoclasts (OC) direct pathologic bone resorption in osteoporosis and inflammatory arthritis. We previously demonstrated that DC-STAMP (Dendritic Cell-Specific Transmembrane protein), a 7-pass transmembrane protein,…Abstract Number: 1167 • 2015 ACR/ARHP Annual Meeting
Treating Experimental Arthritis with Adenoviral Overexpression of IL-22 or with Blocking Antibodies Against Endogenous IL-22 Both Reduces Inflammation and Destruction
Background/Purpose: Interleukin-22 (IL-22) is an IL-10 family cytokine member that was recently discovered to be mainly produced by Th17 cells. Previous studies have indicated the…Abstract Number: 2090 • 2015 ACR/ARHP Annual Meeting
Gender-Specific Pathways Linking Arthritis, Activity Limitation and Incident Heart Disease: A Causal Mediation Analysis of the Canadian Longitudinal National Population Health Survey
Background/Purpose: Arthritis and activity limitation are risk factors for cardiovascular (CVD) morbidity and mortality. As arthritis is a major cause of activity limitation, the objective…Abstract Number: 1206 • 2015 ACR/ARHP Annual Meeting
Presence of ACPA in a Large (>40.000) Population Based Cohort from the Netherlands
Background/Purpose: Anti-citrullinated protein antibodies (ACPA) status provides important information regarding the diagnosis and prognosis of Rheumatoid Arthritis (RA). By using samples from blood bank donors…Abstract Number: 2111 • 2015 ACR/ARHP Annual Meeting
A Study to Evaluate the Efficacy and Safety of Arhalofenate for Preventing Flares and Reducing Serum Uric Acid in Gout Patients
Background/Purpose: Arhalofenate is a novel Urate-Lowering Anti-Flare Therapy (ULAFT) to treat gout. It lowers serum uric acid (sUA) by blocking URAT1, a tubular UA transporter, and…Abstract Number: 1244 • 2015 ACR/ARHP Annual Meeting
Extracellular MicroRNAs in Synovial Fluid Reveal a Marked Proliferative Signature in Patients with Antibiotic-Refractory Lyme Arthritis
Background/Purpose: Lyme arthritis (LA), caused by a tick-borne spirochete Borrelia burgdorferi, usually resolves appropriately with antibiotic treatment, called antibiotic-responsive LA. However, in some patients, arthritis…Abstract Number: 2162 • 2015 ACR/ARHP Annual Meeting
Associations Between Education and Health Status Among Hispanics with Self-Reported Arthritis and/or Joint Pain
Background/Purpose: Understanding the associations between education and health status among Hispanics with arthritis and/or joint pain is crucial in adapting existing arthritis interventions for this…Abstract Number: 1345 • 2015 ACR/ARHP Annual Meeting
The Impact of Prior Antibiotic Treatment on Culture Results of Patients with Septic Arthritis
Background/Purpose: Synovial fluid culture and gram stain offer the most compelling proof of septic arthritis (SA); these tests are indicated in every suspected case. However,…Abstract Number: 2259 • 2015 ACR/ARHP Annual Meeting
Incidence of Obesity, Diabetes and High Blood Pressure Associated with Arthritis: Analysis of the Canadian Longitudinal National Population Health Survey
Background/Purpose: While cross-sectional evidence points to a higher prevalence of cardiovascular (CVD) risk factors in persons with arthritis, longitudinal population based studies are lacking. The…Abstract Number: 1346 • 2015 ACR/ARHP Annual Meeting
The Presentation and Outcomes of Surgically Treated Septic Arthritis: the Impact of Culture Results
Background/Purpose: Clinically-suspected septic arthritis is culture-negative in 18-43% of cases. These patients are often treated surgically with associated morbidity, prolonged hospital stays and high medical…Abstract Number: 2283 • 2015 ACR/ARHP Annual Meeting
Current and Lifetime Smoking Among US Adults with Arthritis: A Serious Clinical and Public Health Issue
Background/Purpose: Smoking's adverse effects include increased risk of joint replacement failure and decreased medication effectiveness (e.g., methotrexate, TNF blockers). Because little is known about the…Abstract Number: 1347 • 2015 ACR/ARHP Annual Meeting
The Presentations and Outcomes of Prosthetic Joint Septic Arthritis: a Comparison of Culture-Positive and Culture-Negative Disease
Background/Purpose: Prosthetic joint septic arthritis (PJSA) may complicate joint replacement in approximately 1-2% of cases. Synovial fluid cultures are negative in up to 25% of…Abstract Number: 2372 • 2015 ACR/ARHP Annual Meeting
Timing of Onset and Cluster with Other Manifestations Influence the Spectrum of Arthritis in Anti Jo-1 Positive Antisynthetase Syndrome: Results from a Multicenter, International, Retrospective Study
Background/Purpose: arthritis, myositis and interstitial lung disease (ILD) are reported in up to 90% of patients affected by antisynthetase syndrome (ASSD) and thus represent the…Abstract Number: 2050 • 2014 ACR/ARHP Annual Meeting
Knee Arthritis Is Positively Associated with Physical Impairment: Conclusion Based on Physical Examinations from a Cross-Sectional Study of 17708 Chinese Residents
Background/Purpose The prevalence of knee arthritis is high in both urban and rural China. Although the association between knee arthritis and limitation of daily activity…Abstract Number: 67 • 2014 ACR/ARHP Annual Meeting
Effects of Exercise on Depressive Symptoms in Adults with Arthritis: A Systematic Review with Meta-Analysis
Background/Purpose: Previous randomized controlled trials have led to conflicting findings regarding the effects of exercise on depressive symptoms in adults with arthritis and other rheumatic…