Abstracts tagged "Arthritis"

Abstract Number: 174 • 2015 ACR/ARHP Annual Meeting
High Resolution Ultrasound of the Midfoot: Sonography Is Superior to Conventional Radiography in Detection of Osteophytes and Erosions in Inflammatory and Non-Inflammatory Joint Disease
Mathis Camerer¹, Boris P. Ehrenstein², Martin Fleck³, Patrick Hoffstetter⁴ and Wolfgang Hartung⁵, ¹Rheumatology and Clinical Immunology, Asklepios Clinic Bad Abbach, Bad Abbach, Germany, ²Department of Rheumatology/Clinical Immunology, Asklepios Medical Center, 93077 Bad Abbach, Germany, ³Department of Internal Medicine I, University of Regensburg, 93042 Regensburg, Germany, ⁴Radiology, Asklepios Clinic Bad Abbach, Bad Abbach, Germany, ⁵Rheumatology & Clinical Immunology, Asklepios Clinic Bad Abbach, Bad Abbach, Germany
Background/Purpose: Ultrasound (US) as well as conventional radiography (CR) are established imaging modalities for the assessment of cortical bone lesions including erosions and osteophytes. Several…
Abstract Number: 1375 • 2015 ACR/ARHP Annual Meeting
S100A8/A9, a Serum and Imaging Biomarker for Assessing Joint Inflammation and Destruction in Experimental Seronegative Arthritis
Edwin J. W. Geven¹, Shahla Abdolahi-Roodsaz¹, Annet Sloetjes¹, Marije I. Koenders¹, Dirk Föll², Johannes Roth³, Thomas Vogl³ and Peter L. E. M. van Lent¹, ¹Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, ²Department of Pediatric Rheumatology and Immunology, University of Münster, Münster, Germany, ³Institute of Immunology, University of Münster, Münster, Germany
Background/Purpose: Seronegative joint diseases such as psoriatic arthritis and juvenile idiopathic arthritis are characterized by the lack of autoantibodies, potent biomarkers used for predicting disease…
Abstract Number: 2438 • 2015 ACR/ARHP Annual Meeting
Clinical Examination of the Temporomandibular Joint; A Eurotmjoint Initiative
Bernd Koos¹, Peter Stoustrup², Lynn R. Spiegel³, Nikolay Tzaribachev⁴, Troels Herlin⁵, Thomas Klit Pedersen⁶ and Marinka Twilt⁷, ¹Orthodontics, University of Rostock, Rostock, Germany, ²Section of Orthodontics, University of Aarhus, Aarhus C, Denmark, ³Rheumatology/Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada, ⁴Pediatric Rheumatology, Center for Rheumatic Diseases, Bad Bramstedt, Germany, ⁵Department of Pediatrics, Århus University Hospital Skejby, Århus, Denmark, ⁶orthodontics, Aarhus University Hospital/Dental school, Aarhus, Denmark, ⁷Pediatric Rheumatology Clinic, Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark
Background/Purpose: Arthritis of the temporomandibular joint (TMJ) in patients with Juvenile Idiopathic Arthritis (JIA) is increasingly recognized. In the last decade, studies report that the…
Abstract Number: 387 • 2015 ACR/ARHP Annual Meeting
Features of 847 Childhood-Onset Systemic Lupus Erythematousus Patients in Three Age-Related Groups at Diagnosis: A Brazilian Multicenter Study
Clovis A Silva¹, Roberta C. Gomes Sr.², Marco F. Silva³, Katia T. Kozu⁴, Eloisa Bonfá⁵, Rosa M R Pereira⁶, Maria Teresa Terreri⁷, Claudia S. Magalhães Sr.⁸, Silvana B. Sacchetti Sr.⁹, Roberto Marini Sr.¹⁰, Melissa Fraga¹¹, Luciana M. Carvalho Sr.¹², Cássia M. Barbosa¹³ and Magda Carneiro-Sampaio Sr.¹⁴, ¹Pediatric Rheumatology, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, ²Pediatric Rheumatology Unit, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ³Pediatric Rheumatology Unit-Children’s Institute,, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, ⁴Pediatrics, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, ⁵Division of Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁶Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁷Pediatrics, Universidade Federal de Sao Paulo, São Paulo, Brazil, ⁸Pediatric Rheumatology Unit, São Paulo State University – Faculdade de Medicina de Botucatu, São Paulo, Brazil, ⁹Pediatric Rheumatology Unit, Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil, ¹⁰Pediatric Rheumatology Unit, State University of Campinas, São Paulo, Brazil, ¹¹Pediatrics, Universidade Federal de São Paulo / UNIFESP, São Paulo, Brazil, ¹²Pediatric Rheumatology Unit, Ribeirão Preto Medical School – University of São Paulo, São Paulo, Brazil, ¹³Pediatric Rheumatology Unit, Hospital Infantil Darcy Vargas, São Paulo, Brazil, ¹⁴Pediatric Allergology and Immunology Unit, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Previous retrospective evaluations suggested that age at diagnosis may influence disease expression in terms of initial clinical presentation, pattern of organ involvement and serological…
Abstract Number: 1394 • 2015 ACR/ARHP Annual Meeting
Clinical Characteristics of Sarcoid Arthropathy: A Population-Based Study
Patompong Ungprasert¹, Cynthia S. Crowson² and Eric L. Matteson³, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Health Sciences Research, Mayo Clinic, Rochester, MN, ³Division of Rheumatology, Department of Internal Medicine and Department of Health Sciences Research, Mayo Clinic, Rochester, MN
Background/Purpose: The epidemiology and clinical characteristics of sarcoid arthropathy are not well-described as only referral-based studies have been reported. This study aimed to use the…
Abstract Number: 2555 • 2015 ACR/ARHP Annual Meeting
14-3-3η As a Novel RA Drug Target: Anti-14-3-3η Monoclonal Antibody Delays the Onset and Mitigates the Severity of Arthritis in CIA Mice
Abedelnasser Abulrob¹, Mario Mercier¹, Slavisa Corluka¹, Roger MacKenzie¹, Shalini Raphael¹, Sara Michienzi², Jane Savill², Yuan Gui², Walter Maksymowych³ and Anthony Marotta², ¹National Research Council of Canada, Ottawa, ON, Canada, ²Augurex Life Sciences Corp., Vancouver, BC, Canada, ³Department of Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: As an extracellular ligand, 14-3-3η potently and concentration-dependently upregulates the expression of multiple factors including TNFα, IL-6, and RANKL and its clinical detection is…
Abstract Number: 786 • 2015 ACR/ARHP Annual Meeting
Anti-Carbamylated Protein Antibodies Identify Systemic Lupus Erythematosus Patients with Erosive Arthritis: Analysis of a Regional Swedish Register
Alf Kastbom¹, Philip Wallin², Michael Ziegelasch¹, Thomas Skogh¹, Leendert Trouw³ and Christopher Sjöwall¹, ¹Department of Clinical and Experimental Medicine, Rheumatology/AIR, Linköping, Sweden, ²Linköping University, Clinical and Experimental Medicine, Sweden, Rheumatology/AIR, Linköping, Sweden, ³Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Articular manifestations affect a majority of patients with systemic lupus erythematosus (SLE), at least at some time during the disease course. Several investigators have…
Abstract Number: 1399 • 2015 ACR/ARHP Annual Meeting
Patterns of Arthropathy in Patients with Cystic Fibrosis
Amanda Schnell¹, Muhammad Imran², Michael Crosser³ and Mehrdad Maz⁴, ¹Internal Medicine, University of Kansas Medical Center, Kansas City, KS, ²Rheumatology, University of Kansas Medical Center, Kansas City, KS, ³Pulmonary and Critical Care, University of Kansas Medical Center, Kansas City, KS, ⁴Division of Rheumatology, University of Kansas Medical Center, Kansas City, KS
Background/Purpose: There are limited published studies about patterns of arthropathy seen in cystic fibrosis (CF) patients. The objective of this study was to determine the…
Abstract Number: 2583 • 2015 ACR/ARHP Annual Meeting
Important Role of CD11c+ Dendritic Cells in Inflammatory Arthritis
Antonia Puchner¹, Victoria Saferding², Eliana Goncalves-Alves³, Gerhard Krönke⁴, Rene Pfeifle⁴, Silvia Hayer⁵, Josef S. Smolen⁶, Kurt Redlich^3,7 and Stephan Blüml³, ¹Department of Rheumatology, Medical University of Vienna, Vienna, Austria, ²Rheumatology, Medical University of Vienna, Vienna, Austria, ³Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ⁴Universitätsklinikum Erlangen, Erlangen, Austria, ⁵Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ⁶Department of Medicine 3, Division of Rheumatology, Medical University Vienna, Vienna, Austria, ⁷Medical University Vienna, Dpt. of Rheumatology, Vienna, Austria
Background/Purpose: Dendritic cells (DCs) play an important role in bridging the innate and the adaptive immune response by serving as antigen presenting cells and are…
Abstract Number: 832 • 2015 ACR/ARHP Annual Meeting
The Validity and Reliability of Online Obituaries As a Source of Mortality Data
Medha Soowamber¹, John T. Granton², Fatemeh Bavaghar-Zaeimi³ and Sindhu R. Johnson^4,5, ¹Rheumatology, University of Toronto/ Toronto Western Hospital, Toronto, ON, Canada, ²Medicine, Univeristiy Health Network Pulmonary Hypertension Programme, Toronto General Hospital and University of Toronto, Toronto, ON, Canada, ³Rheumatology, Toronto Scleroderma Program, Toronto Western Hospital and Mount Sinai Hospital, Toronto, ON, Canada, ⁴Toronto Scleroderma Program, Division of Rheumatology, Toronto Western Hospital, Mount Sinai Hospital, Institue of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada, ⁵Institute of Health Policy, Management and Evaluation,, University of Toronto, Toronto, ON, Canada
Background/Purpose: Loss to follow-up is a major threat to the conduct of chronic disease cohort research. Tracking the survival status of patients who are lost…
Abstract Number: 1428 • 2015 ACR/ARHP Annual Meeting
Subchondral Bone Structure and Pain Behaviors in Complete Freund’s Adjuvant (CFA) Monoarthritis in Mice Treated with Intra-Articular (IA) Neurotoxin
Hollis E. Krug^1,2, Joseph Bert³, Fakhar Abbass⁴, Christopher W. Dorman⁵, Sandra Frizelle⁵ and Maren L. Mahowald^1,2, ¹Medicine, Minneapolis VA Health Care System, Minneapolis, MN, ²Medicine, University of Minnesota, Minneapolis, MN, ³Internal Medicine, Division of Rheumatology, University of Minnesota, Minneapolis, MN, ⁴Minneapolis VA Health Care System, Minneapolis, MN, ⁵Research, Minneapolis VA Health Care System, Minneapolis, MN
Background/Purpose: Bone histomorphometry can define OA changes in rodents and in Antigen-Induced arthritis (AIA) in rats. We produced painful inflammatory monoarthritis in mouse knees with IA…
Abstract Number: 2724 • 2015 ACR/ARHP Annual Meeting
Methotrexate Treatment Could Modulate the Abnormal CD4+T Lymphocyte Subset Distribution in NaÏve Rheumatoid Arthritis Patients
Cristina Bohórquez Heras¹, Lucía Ruiz Gutiérrez¹, Carolina Garcia Torrijos², Ana Turrión Nieves¹, Ana Pérez Gómez¹, Ana Sánchez Atrio¹, Eduardo Cuende¹, Atusa Movasat¹, Fernando Albarrán Hernández¹, Henry Moruno¹, M José León¹, David Diaz², Jorge Monserrat² and Melchor Álvarez de Mon^1,2, ¹University Hospital Príncipe de Asturias, Immune System Diseases, Rheumatology department, Alcalá de Henares, Madrid, Spain, ²Laboratory of Immune System Diseases, Department of Medicine, University of Alcalá, Alcalá de Henares, Madrid, Spain
Background/Purpose: Mechanisms regulating the chronic autoimmune response in rheumatoid arthritis (RA) are not well understood. However, activated T CD4+ play a pivotal role initiating and…
Abstract Number: 834 • 2015 ACR/ARHP Annual Meeting
The Efficacy of Rituximab in Systemic Sclerosis Joint Disease: A Pilot Study
Helena Borrell Paños¹, Javier Narváez², Juan José Alegre³, Ivan Castellvi⁴, Gloria Albert Espi³, Sergi Heredia¹, Elide Toniolo⁴ and Joan Miquel Nolla¹, ¹Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, ²Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, ³Rheumatology Department, Hospital Universitario Doctor Peset, Valencia, Spain, ⁴Rheumatology Unit. Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
Background/Purpose: Between 16 and 20% of patients with systemic sclerosis (SS) have arthritis, which is occasionally erosive. In addition, between 1 and 5% of patients…
Abstract Number: 1441 • 2015 ACR/ARHP Annual Meeting
Marine Oil Supplements for Arthritis Pain: A Systematic Review and Meta-Analysis of Randomized Trials
Ninna Karsbæk Senftleber^1,2, Sabrina Mai Nielsen^3,4, Jens Rikardt Andersen⁴, Henning Bliddal⁵, Simon Tarp³, Lotte Lauritzen⁴, Daniel E. Furst⁶, Maria E. Suarez-Almazor⁷, Anne Lyddiatt⁸ and Robin Christensen⁵, ¹Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Frederiksberg and Bispebjerg, Denmark, ²Department of Nutrition, Exercise and Sports, University of Copenhagen, Frederiksberg, Denmark, ³Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, ⁴Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark, ⁵The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, ⁶Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, ⁷General Internal Medicine, The University of Texas, MD Anderson Cancer Center, Houston, TX, ⁸Musculoskeletal Group, Cochrane Collaboration, Ottawa, ON, Canada
Background/Purpose: Marine oil supplements (MOS) are suggested to have anti-inflammatory properties, but there is no consensus regarding the efficacy of MOS in the management of…
Abstract Number: 2856 • 2015 ACR/ARHP Annual Meeting
Efficacy and Safety of Ustekinumab in Psoriatic Arthritis Patients with Spondylarthritis As Well As Peripheral Arthritis: Results from 2 Phase 3, Multicenter, Double-Blind, Placebo-Controlled Study
Arthur Kavanaugh¹, Luis Puig², Alice B. Gottlieb³, Christopher T. Ritchlin⁴, Yin You⁵, Shu Li⁵, Michael Song⁵, Bruce Randazzo⁵, Proton Rahman⁶ and Iain. B. McInnes⁷, ¹University of California San Diego, La Jolla, CA, ²Universitat Autònoma de Barcelona, Barcelona, Spain, ³Tufts Medical Center, Boston, MA, ⁴Allergy, Immunology and Rheumatololgy Division, University of Rochester Medical Center, Rochester, NY, ⁵Janssen Research & Development, LLC, Spring House, PA, ⁶Rheumatology, Memorial University of Newfoundland, St Johns, NF, Canada, ⁷Institute of Infection, Immunity and Inflammation, College of Medicine, Veterinary Medicine and Life Sciences, University of Glasgow, Glasgow, United Kingdom
Background/Purpose: To evaluate ustekinumab(UST) in a subgroup of psoriatic arthritis (PsA) pts with physician diagnosed spondylarthritis, as well as peripheral arthritis, from the PSUMMIT 1…

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