Abstracts tagged "Arthritis"

Abstract Number: 1008 • 2016 ACR/ARHP Annual Meeting
Advantageous Effect of an Endogenous Retroviral Envelope Protein in Systemic Lupus Erythematosus with Ex Vivo and In Vivo Anti-Inflammatory Potential
Anne Troldborg^1,2, Magdalena Janina Laska³, Ellen-Margrethe Hauge^4,5, Shervin Bahrami⁶ and Kristian Stengaard-Pedersen^7,8, ¹clinical medicine, Aarhus University, Aarhus, Denmark, ²Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ³Biomedicine, Aarhus University, Aarhus, Denmark, ⁴Dept. of Anatomy, Aarhus University, Aarhus, Denmark, ⁵Rheumatology, Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ⁶Clinical Medicine, Aarhus University, Aarhus, Denmark, ⁷Clinical medicine, Aarhus University, Aarhus, Denmark, ⁸Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark
Background/Purpose: Human Endogenous Retroviruses (HERVs) are remnants of retroviral infections in the human germline. Most, but not all, HERV genes have become inactive by accumulation…
Abstract Number: 2190 • 2016 ACR/ARHP Annual Meeting
Prevalence of Severe Joint Pain Among Adults with Doctor-Diagnosed Arthritis— United States, 2002–2014
Kamil E. Barbour¹, Michael Boring¹, Charles Hemlick², Louise Murphy¹ and Jin Qin¹, ¹Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA, ²Centers for Disease Control and Prevention, Atlanta, GA
Background/Purpose: Severe joint pain (SJP) from arthritis may reflect insufficiently managed pain, and SJP can limit an individual’s ability to perform basic functions. We…
Abstract Number: 1030 • 2016 ACR/ARHP Annual Meeting
Synovial Tissue Resident Macrophages Play the Protective Role in the Development of Inflammatory Arthritis in CD11c-Flip-KO Mice
Qi Quan Huang¹, Renee E. Doyle², Robert Birkett³ and Richard M. Pope², ¹Division of Rheumatology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Medicine/Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Medicine/Rheumatology, Northwestern University, Chicago, IL
Synovial Tissue Resident Macrophages Play the protective role in the Development of Inflammatory Arthritis in CD11c-Flip-KO MiceQi-Quan Huang1, Renee Doyle1, Robert Birkett1 and Richard M.…
Abstract Number: 2195 • 2016 ACR/ARHP Annual Meeting
Conceptualizing the Life Course in the Employment Experiences of Working-Aged Adults with Arthritis: A Qualitative Study
Arif Jetha^1,2, Julie Bowring¹, Catherine Connelly², Sean Tucker³, Kathleen Martin Ginis⁴ and Monique A.M. Gignac^5,6, ¹Institute for Work & Health, Toronto, ON, Canada, ²DeGroote School of Business, McMaster University, Hamilton, ON, Canada, ³University of Regina, Regina, SK, Canada, ⁴Department of Kinesiology, McMaster University, Hamilton, ON, Canada, ⁵Instititue for Work and Health, Toronto, ON, Canada, ⁶Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada
Background/Purpose: Research consistently finds that arthritis contributes to work disability. Yet, few studies have examined how employment experiences differ across the life course. This study…
Abstract Number: 3L • 2015 ACR/ARHP Annual Meeting
A Randomised Controlled Trial of the Clinical Effectiveness, Safety and Cost-Effectiveness of Adalimumab in Combination with Methotrexate for the Treatment of Juvenile Idiopathic Arthritis Associated Uveitis
Athimalaipet V Ramanan¹, Andrew D. Dick², Andrew McKay³, Ashley Jones⁴, Paula Williamson⁴, Sandrine Compeyrot-Lacassagne⁵, Ben Hardwick⁴, Helen Hickey⁴, Dyfrig Hughes⁶, Patricia Woo⁵, Diana Benton¹, Clive Edelsten⁵ and Michael W. Beresford⁷, ¹University Hospitals Bristol NHS Foundation Trust, Bristol, United Kingdom, ²University of Bristol, Bristol Eye Hospital, Bristol, United Kingdom, ³Biostatistics, Clinical Trials Research Centre, University of Liverpool, Liverpool, United Kingdom, ⁴Clinical Trials Research Centre, University of Liverpool, Liverpool, United Kingdom, ⁵Great Ormond Street Hospital, London, United Kingdom, ⁶Bangor University, Bangor, United Kingdom, ⁷University of Liverpool, Liverpool, United Kingdom
Background/Purpose: Uveitis associated with Juvenile Idiopathic Arthritis (JIA) is a major cause of morbidity with potentially sight-threatening complications. Despite current screening and (pre-biologic) therapeutic options,…
Abstract Number: 1355 • 2015 ACR/ARHP Annual Meeting
Ankle Periarthritis, a New Sign for Chikungunya : Ultrasound Study of Joint Lesions at the Acute Phase of Chikungunya
Lauren Brunier-Agot¹, Michel DeBandt², George Jean-Baptiste³, Regis Duvauferrier³, Catherine Lebris³ and Andre Cabié⁴, ¹Internal medicine and rheumatology, Zobda Quitman Hospital, Fort de France, Martinique, ²Medicine, Abstract Medical Int'l, Boulogne, France, ³Chu de Martinique, Fort de France, France, ⁴infectious disease, Zobda Quitman Hospital, Fort de France, Martinique
Background/Purpose: Chikungunya (CHIK) is a viral disease transmitted by the Aedes mosquito. The acute phase of the disease combines: fever, fatigue, arthralgia, arthritis, rash .…
Abstract Number: 2382 • 2015 ACR/ARHP Annual Meeting
An Outsourced Health-Enhancing Physical Activity Program for People with Rheumatoid Arthritis. Exploration of the Maintenance Phase
Christina H. Opava¹, Birgitta Nordgren¹, Cecilia Fridén¹, Ingrid Demmelmaier¹, Gunnar Bergström², Ingrid E. Lundberg³, Alyssa B. Dufour^1,4, Thomas Nessen¹ and PARA Study Group, ¹Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Huddinge, Sweden, ²Institute of Environmental Medicine, Unit of Intervention and Implementation Research, Karolinska Institutet, Stockholm, Sweden, ³Karolinska University Hospital, Rheumatology Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden, ⁴Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School & Beth Israel Deaconess Medical Center, Boston, MA
Background/Purpose: Health-enhancing physical activity (HEPA), i.e. at least 150 weekly minutes of moderate-intensity and at least twice-weekly muscle-strengthening activities, is recommended for every adult. Long-term studies on HEPA…
Abstract Number: 174 • 2015 ACR/ARHP Annual Meeting
High Resolution Ultrasound of the Midfoot: Sonography Is Superior to Conventional Radiography in Detection of Osteophytes and Erosions in Inflammatory and Non-Inflammatory Joint Disease
Mathis Camerer¹, Boris P. Ehrenstein², Martin Fleck³, Patrick Hoffstetter⁴ and Wolfgang Hartung⁵, ¹Rheumatology and Clinical Immunology, Asklepios Clinic Bad Abbach, Bad Abbach, Germany, ²Department of Rheumatology/Clinical Immunology, Asklepios Medical Center, 93077 Bad Abbach, Germany, ³Department of Internal Medicine I, University of Regensburg, 93042 Regensburg, Germany, ⁴Radiology, Asklepios Clinic Bad Abbach, Bad Abbach, Germany, ⁵Rheumatology & Clinical Immunology, Asklepios Clinic Bad Abbach, Bad Abbach, Germany
Background/Purpose: Ultrasound (US) as well as conventional radiography (CR) are established imaging modalities for the assessment of cortical bone lesions including erosions and osteophytes. Several…
Abstract Number: 1375 • 2015 ACR/ARHP Annual Meeting
S100A8/A9, a Serum and Imaging Biomarker for Assessing Joint Inflammation and Destruction in Experimental Seronegative Arthritis
Edwin J. W. Geven¹, Shahla Abdolahi-Roodsaz¹, Annet Sloetjes¹, Marije I. Koenders¹, Dirk Föll², Johannes Roth³, Thomas Vogl³ and Peter L. E. M. van Lent¹, ¹Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, ²Department of Pediatric Rheumatology and Immunology, University of Münster, Münster, Germany, ³Institute of Immunology, University of Münster, Münster, Germany
Background/Purpose: Seronegative joint diseases such as psoriatic arthritis and juvenile idiopathic arthritis are characterized by the lack of autoantibodies, potent biomarkers used for predicting disease…
Abstract Number: 2438 • 2015 ACR/ARHP Annual Meeting
Clinical Examination of the Temporomandibular Joint; A Eurotmjoint Initiative
Bernd Koos¹, Peter Stoustrup², Lynn R. Spiegel³, Nikolay Tzaribachev⁴, Troels Herlin⁵, Thomas Klit Pedersen⁶ and Marinka Twilt⁷, ¹Orthodontics, University of Rostock, Rostock, Germany, ²Section of Orthodontics, University of Aarhus, Aarhus C, Denmark, ³Rheumatology/Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada, ⁴Pediatric Rheumatology, Center for Rheumatic Diseases, Bad Bramstedt, Germany, ⁵Department of Pediatrics, Århus University Hospital Skejby, Århus, Denmark, ⁶orthodontics, Aarhus University Hospital/Dental school, Aarhus, Denmark, ⁷Pediatric Rheumatology Clinic, Department of Pediatrics, Aarhus University Hospital, Aarhus, Denmark
Background/Purpose: Arthritis of the temporomandibular joint (TMJ) in patients with Juvenile Idiopathic Arthritis (JIA) is increasingly recognized. In the last decade, studies report that the…
Abstract Number: 387 • 2015 ACR/ARHP Annual Meeting
Features of 847 Childhood-Onset Systemic Lupus Erythematousus Patients in Three Age-Related Groups at Diagnosis: A Brazilian Multicenter Study
Clovis A Silva¹, Roberta C. Gomes Sr.², Marco F. Silva³, Katia T. Kozu⁴, Eloisa Bonfá⁵, Rosa M R Pereira⁶, Maria Teresa Terreri⁷, Claudia S. Magalhães Sr.⁸, Silvana B. Sacchetti Sr.⁹, Roberto Marini Sr.¹⁰, Melissa Fraga¹¹, Luciana M. Carvalho Sr.¹², Cássia M. Barbosa¹³ and Magda Carneiro-Sampaio Sr.¹⁴, ¹Pediatric Rheumatology, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, ²Pediatric Rheumatology Unit, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ³Pediatric Rheumatology Unit-Children’s Institute,, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, ⁴Pediatrics, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, ⁵Division of Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁶Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁷Pediatrics, Universidade Federal de Sao Paulo, São Paulo, Brazil, ⁸Pediatric Rheumatology Unit, São Paulo State University – Faculdade de Medicina de Botucatu, São Paulo, Brazil, ⁹Pediatric Rheumatology Unit, Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil, ¹⁰Pediatric Rheumatology Unit, State University of Campinas, São Paulo, Brazil, ¹¹Pediatrics, Universidade Federal de São Paulo / UNIFESP, São Paulo, Brazil, ¹²Pediatric Rheumatology Unit, Ribeirão Preto Medical School – University of São Paulo, São Paulo, Brazil, ¹³Pediatric Rheumatology Unit, Hospital Infantil Darcy Vargas, São Paulo, Brazil, ¹⁴Pediatric Allergology and Immunology Unit, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
Background/Purpose: Previous retrospective evaluations suggested that age at diagnosis may influence disease expression in terms of initial clinical presentation, pattern of organ involvement and serological…
Abstract Number: 1394 • 2015 ACR/ARHP Annual Meeting
Clinical Characteristics of Sarcoid Arthropathy: A Population-Based Study
Patompong Ungprasert¹, Cynthia S. Crowson² and Eric L. Matteson³, ¹Rheumatology, Mayo Clinic, Rochester, MN, ²Health Sciences Research, Mayo Clinic, Rochester, MN, ³Division of Rheumatology, Department of Internal Medicine and Department of Health Sciences Research, Mayo Clinic, Rochester, MN
Background/Purpose: The epidemiology and clinical characteristics of sarcoid arthropathy are not well-described as only referral-based studies have been reported. This study aimed to use the…
Abstract Number: 2555 • 2015 ACR/ARHP Annual Meeting
14-3-3η As a Novel RA Drug Target: Anti-14-3-3η Monoclonal Antibody Delays the Onset and Mitigates the Severity of Arthritis in CIA Mice
Abedelnasser Abulrob¹, Mario Mercier¹, Slavisa Corluka¹, Roger MacKenzie¹, Shalini Raphael¹, Sara Michienzi², Jane Savill², Yuan Gui², Walter Maksymowych³ and Anthony Marotta², ¹National Research Council of Canada, Ottawa, ON, Canada, ²Augurex Life Sciences Corp., Vancouver, BC, Canada, ³Department of Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: As an extracellular ligand, 14-3-3η potently and concentration-dependently upregulates the expression of multiple factors including TNFα, IL-6, and RANKL and its clinical detection is…
Abstract Number: 786 • 2015 ACR/ARHP Annual Meeting
Anti-Carbamylated Protein Antibodies Identify Systemic Lupus Erythematosus Patients with Erosive Arthritis: Analysis of a Regional Swedish Register
Alf Kastbom¹, Philip Wallin², Michael Ziegelasch¹, Thomas Skogh¹, Leendert Trouw³ and Christopher Sjöwall¹, ¹Department of Clinical and Experimental Medicine, Rheumatology/AIR, Linköping, Sweden, ²Linköping University, Clinical and Experimental Medicine, Sweden, Rheumatology/AIR, Linköping, Sweden, ³Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Articular manifestations affect a majority of patients with systemic lupus erythematosus (SLE), at least at some time during the disease course. Several investigators have…
Abstract Number: 1399 • 2015 ACR/ARHP Annual Meeting
Patterns of Arthropathy in Patients with Cystic Fibrosis
Amanda Schnell¹, Muhammad Imran², Michael Crosser³ and Mehrdad Maz⁴, ¹Internal Medicine, University of Kansas Medical Center, Kansas City, KS, ²Rheumatology, University of Kansas Medical Center, Kansas City, KS, ³Pulmonary and Critical Care, University of Kansas Medical Center, Kansas City, KS, ⁴Division of Rheumatology, University of Kansas Medical Center, Kansas City, KS
Background/Purpose: There are limited published studies about patterns of arthropathy seen in cystic fibrosis (CF) patients. The objective of this study was to determine the…

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