Abstract Number: 0879 • ACR Convergence 2021
Anti-dsDNA Antibodies Increase Systemic Lupus Erythematosus Cardiovascular Risk Impairing the Immune and Cardiovascular Systems
Background/Purpose: This study aimed to delineate the role of anti-dsDNA antibodies on the alterations observed in the gene profile and the activity of immune and…Abstract Number: 0243 • ACR Convergence 2020
The Role of Anti-dsDNA Antibodies in Predicting Incident Lupus Nephritis in Newly Diagnosed Lupus
Background/Purpose: Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus (SLE) that leads to significant morbidity and mortality. Therefore, it is essential to…Abstract Number: 034 • Pediatric Rheumatology Symposium 2020
Chest Computed Tomography Manifestations in Childhood-Onset Systemic Lupus Erythematosus: A Single-Center Cohort Study
Background/Purpose: Intrathoracic involvement in adults with systemic lupus erythematosus (SLE) is relatively common, particularly pleural disease. The prevalence of intrathoracic involvement in childhood-onset SLE (cSLE)…Abstract Number: 265 • ACR/ARP Annual Meeting 2019
Frequency of Performing Anti dsDNA Antibody in an ANA Negative Patient with Clinical Suspicion of SLE in a Single Centre Trial Before and After the Publication of National Guideline
Background/Purpose: In October 2017, the Australian Rheumatology Association widely promoted a list of five recommendations on low-value practices to general clinicians and patients as part…Abstract Number: 1020 • ACR/ARP Annual Meeting 2019
NLRP12 Regulates Interferon-α Expression and Is a Biomarker for Disease Activity of Systemic Lupus Erythematosus
Background/Purpose: Systemic lupus erythematous (SLE) is a systemic autoimmune disease with diverse etiological factors. It was well recognized that interferon (IFN) signature did the perpetration…Abstract Number: 2896 • ACR/ARP Annual Meeting 2019
The Role of Alterations in the Splicing Machinery in the Pathogenesis of Lupus: Does It Impact Lupus Nephritis?
Background/Purpose: The aim of this study was to evaluate whether alterations in the splicing machinery of immune cells could influence the development and activity of…Abstract Number: 1680 • ACR/ARHP Annual Meeting 2018
Serum Calprotectin in Systemic Lupus Erythematosus: Is It a Good Activity Biomarker?
Jordi Camins Fàbregas1, Melania Martinez-Morillo1, Laia Gifre1, Susana Holgado1, Lourdes Mateo2, Maria Aparicio1, Anne Riveros2, Ivette Casafont-Solé1, Yaiza Garcia1, Agueda Prior3, Aina Teniente-Serra4, Eva Martínez-Cáceres4 and Alejandro Olivé-Marqués2, 1Rheumatology, Hospital Universitari Germans Trias i Pujol, Badalona, Spain, 2Hospital Universitari Germans Trias i Pujol, Badalona, Spain, 3Rheumatology, Hospital Universitari Germans Trias i Pujol, Barcelona, Spain, 4Immunology, Hospital Universitari Germans Trias i Pujol, Badalona, Spain
Background/Purpose: Clinical manifestations of systemic lupus erythematosus (SLE) and infections sometimes are difficult to distinguish. In clinical practice low complement and anti(ds)DNA levels are used…Abstract Number: 2129 • ACR/ARHP Annual Meeting 2018
Precipitating Anti-dsDNA Peptide Repertoires in Lupus
Background/Purpose: Anti-double-stranded (ds)DNA autoantibodies are prototypic serological markers of systemic lupus erythematosus (SLE) but little is known about their immunoglobulin variable (IgV) region composition at…Abstract Number: 693 • ACR/ARHP Annual Meeting 2017
The Utility of a Rise in Anti – Double Stranded DNA Antibodies for Predicting Disease Flares in Systemic Lupus Erythematosus. a Meta-Analysis
Background/Purpose: The ability of predicting disease flares in systemic lupus erythematosus (SLE) by serial measurements of antibodies to double stranded DNA (anti-dsDNA) remains uncertain. Previous…Abstract Number: 703 • ACR/ARHP Annual Meeting 2017
Clinical Value of Autoantibodies for Lupus Myelitis and Its Subtypes: A Systematic Review
Background/Purpose: We conducted a systematic review to investigate the clinical value of clinical characteristics and autoantibodies, especially lupus-specific antibodies, for lupus myelitis and its subtypes.…Abstract Number: 704 • ACR/ARHP Annual Meeting 2017
Detection of dsDNA Antibodies By New Fluoroimmunoassay with Comparable Diagnostic Sensitivity and Specificity to Farr-Ria
Background/Purpose: Antibodies against double-stranded deoxyribonucleic acid (anti-dsDNA) are a useful and valuable serological marker for diagnosis of systemic lupus erythematosus (SLE). Studies suggest strong correlation…Abstract Number: 833 • ACR/ARHP Annual Meeting 2017
Chronic Cutaneous Lupus Erythematosus Patients Have a Breakdown in Autoreactive VH4.34 Antibody Tolerance While Maintaining Tolerance to dsDNA and Chromatin
Background/Purpose: While the contribution of humoral immunity to SLE is well established, the role it plays in chronic cutaneous lupus erythematosus (CCLE) is less clear.…Abstract Number: 1811 • ACR/ARHP Annual Meeting 2016
Systemic Lupus Erythematosus: Detailed Anatomy of a Cohort (follow-up for more than 35 years).
Background/Purpose: Very long-term follow-up has rarely been reported in lupus patients. We report on the follow up of (up to 37 years) of our lupus…Abstract Number: 2066 • ACR/ARHP Annual Meeting 2016
Anti-Ds-DNA Antibodies Regulate Atherothrombosis in Systemic Lupus Erythematosus through the Induction of Netosis, the Prothrombotic and Proinflammatory Activities of Monocytes and the Endothelial Activation
Background/Purpose: The role of anti-dsDNA in the pathogenesis of the systemic lupus erythematosus (SLE) has been clearly established. However, the influence of these autoantibodies in…Abstract Number: 2937 • ACR/ARHP Annual Meeting 2016
Regulation of Follicular Helper T (TFH) Cells By ROCK2 (Rho-associated coiled-coil containing protein kinase 2)
Background/Purpose: Follicular helper T (TFH) cells promote humoral responses and serve as a limiting factor for the selection of high affinity germinal center B cells.…
ACR Meeting Abstracts