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Abstracts tagged "Ankylosing spondylitis (AS)"

  • Abstract Number: 2940 • 2014 ACR/ARHP Annual Meeting

    Do Patients with Non-Radiographic Axial Spondyloarthritis and Ankylosing Spondylitis Respond Similarly Well to Nsaids? – a Prospective Study Including Magnetic Resonance Imaging

    Xenofon Baraliakos1, Uta Kiltz1, Frank Heldmann1, Heiner Appel2, Friedrich Dybowski3, Manfred Igelmann4, Ludwig Kalthoff5, Dietmar Krause6, Hans-Jürgen Menne7, Ertan Saracbasi8, Elmar Schmitz-Bortz9 and Jürgen Braun1, 1Rheumazentrum Ruhrgebiet, Herne, Germany, 2Rheumatology and Nephrology Practice, Hamm, Germany, 3Rheumatology Practice, Herne, Germany, 4Rheumatology Practice, Bochum, Germany, 5Rheumatology practice, Herne, Germany, 6Rheumatology practice, Gladbeck, Germany, 7Rheumatology practice, Dortmund, Germany, 8Rheumatology practice, Oberhausen, Germany, 9Rheumatology practice, Hattingen, Germany

    Background/Purpose: Patients classified as axial spondyloarthritis (axSpA) may have ankylosing spondylitis (AS) or non-radiographic axSpA (nr-axSpA). Treatment recommendations for AS consider non-steroidal anti-inflammatory drugs (NSAIDs)…
  • Abstract Number: 2590 • 2014 ACR/ARHP Annual Meeting

    Comparison of Radiographic Damage Score in Ankylosing Spondylitis According to Tumor Necrosis Factor Inhibitor: Observation Study of Korean Spondyloarthropathy Registry (OSKAR) Data

    Tae-Jong Kim1, JI Hui SHIN2, Il-Hoon Sung3, Seunghun Lee4, Kyung-Bin Joo5 and Tae-Hwan Kim6, 1Chonnam Nat`l University Medical School&Hospital, Gwangju, South Korea, 2Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 3Orthopaedic surgery, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 4Department of Radiology, Department of Radiology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 5Department of Radiology, Department of Radiology, Hanynag University Hospital for Rheumatic Diseases, Seoul, South Korea, 6Division of Rheumatology, Department of Internal Medicine, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea

    Background/Purpose To evaluate the influence of tumor necrosis factor (TNF) blocker on the radiographic damage in ankylosing spondylitis (AS).  Methods . A total of 610…
  • Abstract Number: 1599 • 2014 ACR/ARHP Annual Meeting

    Comparison of Rheumatoid Arthritis, Ankylosing Spondylitis, and Psoriatic Arthritis Pregnancies: Disease Activity, Treatment, and Outcomes

    Megan E. B. Clowse, Rheumatology, Duke University Medical Center, Durham, NC

    Background/Purpose:   While it has long been reported that rheumatoid arthritis (RA) improves with pregnancy, there is very limited information about ankylosing spondylitis (AS) or…
  • Abstract Number: 597 • 2014 ACR/ARHP Annual Meeting

    Inflammatory Burden in Recent-Onset Axial Spondyloarthritis

    Juan Jose Aznar Sánchez1, Raul Veroz Gonzalez1, Adela Gallego Flores1, Tamara Libertad Rodriguez Araya1, Piter José Cossio Jimenez2 and Eugenio Chamizo Carmona1, 1Rheumatology, Hospital de Mérida, Mérida, Spain, 2Hospital de Mérida, Mérida, Spain

    Background/Purpose Patients with Non-Radiographic Axial Spondylarthritis (non-Rx AxSpA) don't presnt with different clinical manifestations than patients with Ankilosing Spondylitis (AS), although the inflammatory burden measured…
  • Abstract Number: 568 • 2014 ACR/ARHP Annual Meeting

    Secondary Amyloidosis Complicating Spondyloarthritis: Still Present after All These Years

    Samantha Rodriguez-Muguruza1, Melania Martínez-Morillo1, Susana Holgado1, Maria Lourdes Mateo1, Juana Sanint1, Anne Riveros-Frutos2, Jeronima Cañellas1, Xavier Tena1 and Alejandro Olivé Marqués1, 1Rheumatology, Hospital Universitari Germans Trias i Pujol, Barcelona, Spain, 2Rheumatology, Hospital Universitario Germans Trias i Pujol, Badalona, Spain

    Background/Purpose: Secondary amyloidosis (AA) is a disorder caused by deposition of insoluble amyloid A fibrils in different tissues and organs. It is a rare and…
  • Abstract Number: 2827 • 2014 ACR/ARHP Annual Meeting

    Cervical Spine Fracture and Mortality in Ankylosing Spondylitis

    Katherine D. Wysham1, Sara G. Murray2, Nancy K. Hills3, Edward H. Yelin4 and Lianne S. Gensler5, 1Internal Medicine, University of California, San Francisco, San Francisco, CA, 2Medicine, University of California, San Francisco, San Francisco, CA, 3Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, 4Arthritis Research Group, University of California, San Francisco, San Francisco, CA, 5Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA

    Background/Purpose: Little data exist regarding mortality in Ankylosing Spondylitis (AS) patients. We performed a population-based study of diagnoses associated with hospital mortality in AS.  Methods:…
  • Abstract Number: 2585 • 2014 ACR/ARHP Annual Meeting

    Association of Smoking with Acute Phase Reactants and Molecules Involved in Bone Formation in Patients with Ankylosing Spondylitis

    Grigorios Sakellariou1, Spyros Gerou2, Dimitrios Oikonomou3 and Fares Sayegh4, 1Rheumatology, 424 General Military Hospital, Thessaloniki, Greece, 2Laboratories "Analysis", Thessaloniki, Greece, 3Biopathology, 424 General Military Hospital, Thessaloniki, Greece, 43rd Orthopaedic, "Papageorgiou" General Hospital, Thessaloniki, Greece

    Background/Purpose: In patients with ankylosing spondylitis (AS), smoking is associated with increased disease activity and more radiographic damage. However, the mechanisms underlying the effects of…
  • Abstract Number: 1596 • 2014 ACR/ARHP Annual Meeting

    Clinical Characteristics and Outcome of Golimumab Treatment Differs Between Bio-naïve and Patients Previously Exposed to Biologicals. Nationwide Results on Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA), Ankylosing Spondylitis (AS) and Other Spondylarthritidies (SpA)

    Saedis Saevarsdottir1, Michele Santacatterina2, Carl Turesson3, Helena Forsblad4, Lennart Jacobsson4 and Staffan Lindblad5, 1Rheumatology Unit, Department of Medicine, Karolinska institutet and Karolinska University Hospital, Stockholm, Sweden, 2Biostatistics Core Facility, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, 3Section of Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, 4Dept of Rheumatology & Inflammation Research, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 5Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Stockholm, Sweden

    Background/Purpose Golimumab is a TNF inhibiting biological drug that was approved in Sweden in 2010 for the treatment of RA, PsA and AS. Our previous…
  • Abstract Number: 596 • 2014 ACR/ARHP Annual Meeting

    Clinical Value of ASDAS Index in Spanish Patients with Ankylosing Spondylitis

    Agusti Sellas-Fernandez1, Jose Luis Guerra Vázquez2, Jose Luis Casals3, Carlos Gonzalez Fernandez4, Roberto Miguelez5, José Rosas6, Antonio Fernandez-Nebro7, Cilia Peralta Ginés8, Carlos Montilla-Morales9, Xavier Juanola10, Miguel Ángel Abad11, Alberto Alonso12, Azucena Hernández-Sanz13, Luis Francisco Linares14, Julio Medina15, Joana Rovira16, Juan Carlos Torre-Alonso17, Alfredo Willisch18, Eduardo Collantes-Estevez19 and Ana Ruiz-Zorrilla20, 1H. Vall d'Hebron, Barcelona, Spain, 2H. Arquitecto Marcide, La Coruña, Spain, 3H. Virgen de la Victoria, Málaga, Spain, 4Rheumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain, 5H. de Móstoles, Madrid, Spain, 6Rheumatology, Hospital Marina Baixa, Villajoyosa, Valencia, Alicante, Spain, 7Rheumatology, Hospital Regional Universitario Carlos Haya, Málaga, Spain, 8H. Clínico Lozano Blesa, Zaragoza, Spain, 9H. de Salamanca, Salamanca, Spain, 10Rheumatology, University Hospital Bellvitge, Barcelona, Spain, 11Hospital Virgen del Puerto, Cáceres, Spain, 12Hospital de Cruces, Bilbao, Spain, 13H. Virgen de la Salud, Toledo, Spain, 14Hospital Virgen de la Arrixaca., Murcia, Spain, 15Hospital Clínico, Valladolid, Spain, 16Mutua Terrasa, Barcelona, Spain, 17Rheumatology Department, H. Monte Naranco, Oviedo, Spain, 18Complexo Hospitalario de Ourense, Ourense, Spain, 19Hospital Reina Sofía, Córdoba, Spain, 20Abbvie, Madrid, Spain

    Background/Purpose The ASDAS (ankylosing spondylitis disease activity score) was developed to overcome some of the deficiencies of BASDAI (Bath Ankylosing Disease Activity Spondyltis Index). In…
  • Abstract Number: 544 • 2014 ACR/ARHP Annual Meeting

    Observed Incidence Rates of Uveitis over 96 Weeks of Certolizumab Pegol Treatment in Patients with Axial Spondyloarthritis

    James T. Rosenbaum1,2, Martin Rudwaleit3, Robert B. M. Landewé4, Helena Marzo-Ortega5,6, Joachim Sieper7, Désirée M. van der Heijde8, Owen Davies9, Christian Stach10, Tommi Nurminen10 and Atul A. Deodhar11, 1OHSU, Portland, OR, 2Arthritis and Rheumatic diseases, Oregon Health and Science University, Portland, OR, 3Endokrinologikum, Berlin, Germany, 4Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands, 5Leeds Teaching Hospitals NHS Trust and NIHR Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, 6University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, 7Rheumatology Department,, University Hospital Charité, Berlin, Germany, 8Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 9UCB Pharma, Slough, United Kingdom, 10UCB Pharma, Monheim, Germany, 11Oregon Health and Sciences University, Portland, OR

    Background/Purpose: Axial spondyloarthritis (axSpA) is characterized by inflammation in the spine and sacroiliac joints, but can also manifest as inflammation at extra-spinal sites, most commonly…
  • Abstract Number: 2829 • 2014 ACR/ARHP Annual Meeting

    Spondyloarthritis Is Associated with Increased Cardiovascular and Cerebrovascular Mortality

    Nigil Haroon1, Nisha Nigil Haroon2, Ping Li3, Michael Paterson3 and Robert D. Inman4, 1Toronto Western Research Institute, Toronto, ON, Canada, 2Medicine, University of Toronto, Toronto, ON, Canada, 3Institute of Clinical Evaluative Sciences, Toronto, ON, Canada, 4Immunlogy and Institute of Medical Science, University of Toronto and Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose OnSpA is a population-based study of spondyloarthritis (SpA) based on a provincial population of over 13 million. Patients with SpA are thought to be…
  • Abstract Number: 2571 • 2014 ACR/ARHP Annual Meeting

    Disease Activity and Risk of Cardiovascular Disease in Patients with Ankylosing Spondylitis with High and Low Body Mass Index

    Inger Jorid Berg1, Anne Grete Semb2, Désirée van der Heijde3,4, Tore K. Kvien4, Hanne Dagfinrud4, Jonny Hisdal5,6 and Sella A. Provan2, 1Dep of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 3Leiden University Medical Center, Leiden, Netherlands, 4Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 5Section of Vascular Investigations, Oslo University Hospital Aker, Oslo, Norway, 6Faculty of Medicine, University of Oslo, Oslo, Norway

    Background/Purpose Patients with ankylosing spondylitis (AS) have increased risk of cardiovascular disease (CVD), but the mediators of this increased risk are not known. Obesity is…
  • Abstract Number: 1540 • 2014 ACR/ARHP Annual Meeting

    Treatment Patterns of Biologics Used in Rheumatoid Arthritis and Ankylosing Spondylitis in the US Veterans Population

    Brian Sauer1, Chia-Chen Teng1, Tao He1, Jianwei Leng2, Chao-Chin Lu1, Neel Shah3, David J. Harrison4, Derek Tang4 and Grant W. Cannon5, 1Salt Lake City VA and University of Utah, Salt Lake City, UT, 2Salt Lake City VA and University of Utah, Salt Lake Citty, UT, 31 Amgen Center Dr, Amgen Inc., Thousand Oaks, CA, 4Amgen Inc., Thousand Oaks, CA, 5Division of Rheumatology, Salt Lake City VA and University of Utah, Salt Lake City, UT

    Background/Purpose: Biologics used for rheumatoid arthritis (RA) and ankylosing spondylitis (AS), including tumor necrosis factor blockers, are a key area of focus for Veterans Affairs…
  • Abstract Number: 595 • 2014 ACR/ARHP Annual Meeting

    Radiographic Sacroiliitis Progression in an Early Axial Spondyloarthritis Cohort

    Concepcion Castillo-Gallego1, Jesus Sanz2, Carmen Martin-Hervas3, Mireia Moreno4, Victoria Navarro-Compán5, Diana Peiteado1, Jorge Gratacos-Masmitja6, Eugenio De Miguel7 and Emilio Martín-Mola1, 1Rheumatology, Hospital La Paz - IdiPaz, Madrid, Spain, 2Rheumatology, Hospital Puerta de Hierro Majadahonda, Madrid, Spain, 3Radiology, Hospital Universitario La Paz, Madrid, Spain, 4Rheumatology, University Hospital Parc Taulí, Sabadell, Spain, 5Rheumatology, Rheumatologist, Madrid, Spain, 6Parc Tauli, S/N, Hospital Parc Tauli, Sabadell, Spain, 7Department of Rheumatology, Hospital Universitario La Paz, Madrid, Spain

    Background/Purpose: The current concept of axial Spondyloarhtritis (axSpA) considers non-radiographic axSpA (nr-axSpA) and Ankylosing Spondylitis (AS) as two stages of one disease. There are limited…
  • Abstract Number: 543 • 2014 ACR/ARHP Annual Meeting

    Disease Activity and Clinical Response Early in the Course of Treatment Predict Long-Term Outcomes in Axial Spondyloarthritis Patients Treated with Certolizumab Pegol

    Désirée M. van der Heijde1, Atul A. Deodhar2, Owen Davies3, Tommi Nurminen4 and Martin Rudwaleit5, 1Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Arthritis and Rheumatic diseases, Oregon Health and Science University, Portland, OR, 3UCB Pharma, Slough, United Kingdom, 4UCB Pharma, Monheim, Germany, 5Endokrinologikum, Berlin, Germany

    Background/Purpose: Early response to anti-TNF therapy has been shown to be a strong predictor of good long-term outcomes in ankylosing spondylitis (AS).1 However, early identification…
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