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Abstracts tagged "Ankylosing spondylitis (AS)"

  • Abstract Number: 2169 • 2016 ACR/ARHP Annual Meeting

    Presence of Cardiovascular Risk Factors Across Different Inflammatory Joint Disease Entities: Results from a Norwegian, Multi-Centre Project

    Grunde Wibetoe1, Eirik Ikdahl2, Silvia Rollefstad2, Anne Salberg3, Dag Magnar Soldal4, Tore K Kvien5, Glenn Haugeberg6 and Anne Grete Semb7, 1Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2Diakonhjemmet Hospital, Oslo, Norway, 3Hospital for Rheumatic Diseases, Lillehammer, Norway, 4Rheumatology, Hospital of Southern Norway, Kristiansand, Norway, 5Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 6Martina Hansens Hospital, Bærum, Norway, 7Preventive Cardio-Rheuma clinic, Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway

    Background/Purpose: EULAR recommendations for cardiovascular disease (CVD) risk management in inflammatory joint diseases (IJD) advocates annual CVD risk assessments to reduce the increased CVD risk.…
  • Abstract Number: 3123 • 2016 ACR/ARHP Annual Meeting

    Rare Mediterranean Fever (MEFV) Gene Polymorphisms Are Associated with Ankylosing Spondylitis in Turkish and Iranian Population

    Zhixiu Li1, Servet Akar2, Handan Yarkan3, Pinar Cetin3, Gerçek Can3, Gökce Kenar3, Omer Nuri Pamuk4, Yavuz Pehlivan5, Katie Cremin6, Erika De Guzman1, Jessica Harris1, Ahmad Reza Jamshidi7, Mahdi Vojdanian7, Nooshin Ahmadzadeh7, Mahdi Mahmoudi7, Matthew A. Brown1 and Nurullah Akkoc3, 1Translational Genomics Group, Institute of Health and Biomedical Innovation, Queensland University of Technology, Translational Research Institute, Brisbane, Australia, Brisbane, Australia, 2Department of Rheumatology, İzmir Katip Çelebi University, School of Medicine, İzmir, Turkey, İzmir, Turkey, 3Department of Rheumatology, Dokuz Eylul University, Faculty of Medicine, İzmir, Turkey, İzmir, Turkey, 4Department of Rheumatology, Trakya University Medical Faculty, Edirne, Turkey, Edirne, Turkey, 5Department of Rheumatology, Uludag University Medical Faculty, Bursa, Turkey, Bursa, Turkey, 6The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Australia, Brisbane, Australia, 7Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran, Tehran, Iran (Islamic Republic of)

    Background/Purpose: Ankylosing spondylitis (AS) is a highly heritable inflammatory arthritis common in both Turkish and Iranian populations. Familial Mediterranean Fever (FMF) is an autosomal recessive…
  • Abstract Number: 100 • 2016 ACR/ARHP Annual Meeting

    Patient Support Program for Adalimumab-Treated Patients in Brazil: Impact on Patients’ Adherence and Persistence

    Roger A. Levy1, Vanessa Teich2, Roberta Fernandes2, Anna Gulart2, Leonardo Chaves3, Vishvas Garg4 and Martha Skup5, 1Rheumatology, Department of Rheumatology, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brazil, 2Sense Company, São Paulo, Brazil, 3AbbVie Inc., Chicago, IL, 4AbbVie Inc, North Chicago, IL, 5AbbVie Inc., North Chicago, IL

    Background/Purpose: The Brazilian public healthcare system covers treatment with adalimumab for rheumatoid arthritis, Crohn's disease, ankylosing spondylitis and psoriatic arthritis, in line with local guidelines.…
  • Abstract Number: 715 • 2016 ACR/ARHP Annual Meeting

    Are Patients with Ankylosing Spondylitis Willing to Pay for Treatment with Infliximab?

    Casper Webers1,2, Ivette Essers1,2, Astrid van Tubergen1,2, Jürgen Braun3, Frank Heldmann4, Xenofon Baraliakos5 and Annelies Boonen2,6, 1Department of Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, 2School for Public Health and Primary Care (CAPHRI), Maastricht University, Maastricht, Netherlands, 3Rheumazentrum Ruhrgebiet, Herne, Germany, 4Zeisigwaldkliniken Bethanien, Chemnitz, Germany, 5Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 6Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands

    Background/Purpose: In view of the continuous pressure of biologicals on healthcare budgets, it is essential to assess the value of biologicals for patients from different…
  • Abstract Number: 1426 • 2016 ACR/ARHP Annual Meeting

    Using Self-Reported Patient Experiences to Understand Patient Burden: Learnings from Digital Patient Communities in Ankylosing Spondylitis

    Prashanth Sunkureddi1, Dawn Gibson2, Stephen Doogan3, John Heid4, Samir Benosman5 and Yujin Park6, 1Rheumatology, Clear Lake Rheumatology Center, Nassau Bay, TX, 2The Global Healthy Living Foundation, Upper Nyack, NY, 3Real Life Sciences, New York, NY, 4Kinapse, Inc, London, United Kingdom, 5Advisory Services, Kinapse, Inc, London, United Kingdom, 6Novartis Pharmaceuticals Corporation, East Hanover, NJ

    Background/Purpose: Ankylosing Spondylitis (AS) is a chronic inflammatory disorder of the spinal joints that can lead to severe, chronic pain and discomfort. There is a…
  • Abstract Number: 2177 • 2016 ACR/ARHP Annual Meeting

    Specificity of Spinal Pain Features in Assessment and Classification of Spondyloarthritis

    Sjef Van Der Linden1, Heinz Baumberger2 and Muhammad Asim Khan3, 1Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, 2N.A., Swiss Ankylosing Spondylitis Patient Society, 7017 Flims Dorf, Switzerland, 3Medicine/ Rheumatology, Case Western Reserve Univ, Cleveland, OH

    Background/Purpose: Classification criteria lacking specificity cause inclusion of many false positives in settings with low prevalence of disease. The ASAS axial spondyloarthritis (axSpA) criteria have…
  • Abstract Number: 3155 • 2016 ACR/ARHP Annual Meeting

    Zygapophyseal Joint Fusion in Ankylosing Spondylitis Assessed Using Computed Tomography: Associations with Syndesmophytes and Spinal Motion

    Sovira Tan1, Jianhua Yao2, Lawrence Yao3, John Flynn4 and Michael Ward1, 1NIAMS/NIH, Bethesda, MD, 2Radiology and Imaging Sciences, NIH Clinical Center, Bethesda, MD, 3Radiology and Imaging Sciences, NIH, Bethesda, MD, 4Dept of Medicine, Johns Hopkins University, Baltimore, MD

    Background/Purpose: Both zygapophyseal joint (ZJ) fusion and syndesmophytes contribute to structural spine damage in Ankylosing Spondylitis (AS). However, because ZJs are difficult to visualize on…
  • Abstract Number: 613 • 2016 ACR/ARHP Annual Meeting

    Immunogenicity of Anti-TNF Therapies in Patients with Inflammatory Rheumatic Diseases and Secondary Failure: A Multicentre Study of 570 Patients

    Alejandro Balsa1, Raimon Sanmarti2, José Rosas3, Susana Gomez Castro4, Ana Cabez4, Victor Martin4 and María Montoro4, 1Rheumatology, IdiPAZ, Hospital Universitario La Paz, Madrid, Spain, 2Rheumatology Department, Hospital Clínic de Barcelona, Barcelona, Spain, 3Rheumatology, Hospital Marina Baixa, Villajoyosa (Alicante), Spain, 4Pfizer, Madrid, Spain

      Abstract   Immunogenicity of anti-TNF therapies in Patients with inflammatory rheumatic Diseases and secondary failure: a multicentre study of 570 patients.   Background/Purpose: The treatment of…
  • Abstract Number: 716 • 2016 ACR/ARHP Annual Meeting

    Radiographic Progression and Changes in Inflammation and Structural Damage on Serial MRI Examinations over 5 Years in Patients with Ankylosing Spondylitis Treated with TNF-Alpha Inhibitors

    Susanne Juhl Pedersen1, Ulrich Weber2, Roula Said Nahal3, Inge Juul Sorensen1, Anne Gitte Loft4, Niels Tvede1, Gina Kollerup1, Lars Juul1, Gorm Thamsborg1, Ole Rintek Madsen1, Jakob M. Møller5, Lone Balding6, Anne Grethe Jurik7 and Mikkel Østergaard8, 1Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, 2Department of Research, King Christian 10th Hospital for Rheumatic Diseases, Graasten, Denmark, 3Ambroise Paré Hospital, Boulogne-Billancourt, France, 4Departments of Rheumatology at Vejle and Aarhus Hospitals, Vejle and Aarhus, Denmark, 5Department of Radiology, Copenhagen University Hospital Herlev and Gentofte, Herlev, Denmark, 6Department of Radiology, Copenhagen University Hospital Herlev and Gentofte, Copenhagen, Denmark, 7Dept. of Radiology, Aarhus University Hospital, Aarhus, Denmark, 8Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark, Copenhagen, Denmark

    Background/Purpose: Only few studies have investigated long-term radiographic progression in the spine of patients with ankylosing spondylitis (AS). Moreover, no studies have reported changes in…
  • Abstract Number: 1427 • 2016 ACR/ARHP Annual Meeting

    The Importance of Outcome Measures in Ankylosing Spondylitis – Validity of the Routine Assessment of Patient Index Data 3 in a Real World Cohort

    Sergio Schwartzman1, Keith Knapp2, Gary Craig3 and Discus, 1Rheumatology, Hospital for Special Surgery, New York, NY, 2Arthritis Northwest PLLC., Spokane, WA, 3Discus Analytics LLC., Spokane, WA

    Background/Purpose: Outcome measures in AS are well established in clinical trial settings but infrequently used in real-world (RW) practice.  These measures include the BASDAI, BASFI,…
  • Abstract Number: 2442 • 2016 ACR/ARHP Annual Meeting

    Use of Nonsteroidal Anti-Inflammatory Drugs in Pregnant Women with Inflammatory Arthritis

    Neda Amiri1, Gretchen Bandoli2, Diana L Johnson2 and Christina D. Chambers2, 1Division of Rheumatology, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada, 2Pediatrics, University of California, San Diego, La Jolla, CA

    Use of Nonsteroidal Anti-inflammatory Drugs in Pregnant Women with Inflammatory Arthritis Background/Purpose: Nonsteroidal anti-inflammatory drugs (NSAIDs) are generally contraindicated in the third trimester of pregnancy…
  • Abstract Number: 629 • 2016 ACR/ARHP Annual Meeting

    Golimumab Improves Patient-Reported Outcomes and Socio- and Health-Economic Parameters in Patients with Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA), and Ankylosing Spondylitis (AS): Results from a Non-Interventional Clinical Evaluation in Germany

    Klaus Krüger1, GR Burmester2, Siegfried Wassenberg3, Martin Bohl-Buehler4 and Matthias H. Thomas5, 1Praxiszentrum St. Bonifatius, München, Germany, 2Charité – University Medicine Berlin, Berlin, Germany, 3Rheumazentrum, Ratingen, Germany, 4Friedrich-Ebert-Str. 35, Rheumahaus, Potsdam, Germany, 5Medical Affairs, MSD Sharp & Dohme GmbH, Bünde, Germany

    Background/Purpose:  Golimumab (GLM) has shown its efficacy and safety in various randomized clinical trials with patients eligible for clinical studies. Data from patient-reported outcomes (PROs)…
  • Abstract Number: 717 • 2016 ACR/ARHP Annual Meeting

    NSAID Use and Functional Impairment in Ankylosing Spondylitis

    Mark Hwang1, Seth Eisen1, MinJae Lee2, Michael Ward3, Lianne S. Gensler4, Prabha Ranganathan5, Johnathan Jia6, Amirali Tahanan2, Matthew A. Brown7, Mohammad H. Rahbar2, Michael Weisman8 and John D. Reveille9, 1Internal Medicine-Rheumatology, Washington University in Saint Louis, School of Medicine, Saint Louis, MO, 2Biostatistics/Epidemiology/Research Design (BERD) Core | Center for Clinical and Translational Sciences, University of Texas-McGovern Medical School, Houston, TX, 3NIH/NIAMS, Bethesda, MD, 4Medicine/Rheumatology, UCSF, San Francisco, CA, 5Washington University in Saint Louis, School of Medicine, Saint Louis, MO, 6University of Texas-McGovern Medical School, Houston, TX, 7The University of Queensland Diamantina Institute, Brisbane, Australia, 8Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 9Rheumatology, University of Texas-McGovern Medical School, Houston, TX

    Background/Purpose:   Ankylosing spondylitis (AS) is a chronic inflammatory disease with significant burden to patients and society.  NSAIDs are the first line pharmacologic therapy in…
  • Abstract Number: 1429 • 2016 ACR/ARHP Annual Meeting

    Patient-Reported Outcomes Measures and Economical Burden of Patients with Ankylosing Spondylitis in a Chinese Prospective Cohort with Smart Management System for Spondyloarthritis

    Qiongfang Wen, Xiaojian Ji, Jinshui Yang, Jian Zhu, Jianglin Zhang and Feng Huang, Rheumatology, Chinese PLA General Hospital, Beijing, China

    Background/Purpose: Ankylosing Spondylitis (AS) is characterized by relatively young onset age, easily causing spinal deformity and stiffness, and seriously influencing the health related Quality of…
  • Abstract Number: 2458 • 2016 ACR/ARHP Annual Meeting

    Erectile Dysfunction in Men with Rheumatic Diseases: A Systematic Review

    Omid Zahedi Niaki1, Christian A. Pineau2, Sasha Bernatsky3,4 and Evelyne Vinet3, 1Université de Montréal, Montreal, QC, Canada, 2McGill University Health Centre, Montreal, QC, Canada, 3Divisions of Rheumatology and Clinical Epidemiology, McGill University Health Centre, Montreal, QC, Canada, 4Clinical Epidemiology, Research Institute of the McGill University Health Centre, Montreal, QC, Canada

    Background/Purpose: Given the obvious female predominance of rheumatic diseases, significant attention has already been drawn to the impact of these conditions on female sexual function.…
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