Abstracts tagged "Ankylosing spondylitis (AS)"

Abstract Number: 570 • 2019 ACR/ARP Annual Meeting
Pattern and Influential Factors in Promoting Treat-to-Target (T2T) for Follow-up of Ankylosing Spondylitis (AS) Patients with a Rheumatologist-patient Interactive Smart System of Disease Management (SSDM): A Cohort Study from China
Jing Xue¹, Hui Song ², Hongzhi Wang ³, Jianlin Huang ⁴, Wenqiang Fan ⁵, Hua Wei ⁶, Hongbin Li ⁷, Weili Liu ⁸, Jin Zhang ⁹, Henglian Wu ¹⁰, Bei Wang ¹¹, Jianhua Xu ¹², Yan Huang ¹³, Hongjun Zhao ¹⁴, Zhiguo Wang ¹⁵, Zhiyong Huang ¹⁶, Xiaohong He ¹⁷, Wenhui Huang ¹⁸, Qiwen Ma ¹⁹, Bing Wu ²⁰, Yuhua Jia ²¹, Yuan Liu ²², Hui Xiao ²², Fei Xiao ²³ and Huaxiang Wu ¹, ¹The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China (People's Republic), ²Beijing Jishuitan Hospital, Beijing, Beijing, China (People's Republic), ³JiaXing First Hospital, Jiaxing, Zhejiang, China (People's Republic), ⁴The sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China (People's Republic), ⁵Central Hospital of XinXiang, Xinxiang, Hainan, China (People's Republic), ⁶Northern Jiangsu People's Hospital, Yangzhou, China (People's Republic), ⁷The Affiliated Hospital of Inner Mongolia Medical University, Huhehaote, Nei Mongol, China (People's Republic), ⁸Ningbo Medical Center Lihuili Hospital, Ningbo, Zhejiang, China (People's Republic), ⁹[email protected], Ningbo, Zhejiang, China (People's Republic), ¹⁰Dongguan donghua hospital, Dongguan, Guangdong, China (People's Republic), ¹¹Beijing Hospital of Traditional Chinese Medicine, Beijing, Beijing, China (People's Republic), ¹²First Affiliated Hospital of Medical University Of Anhui, Hefei, Anhui, China (People's Republic), ¹³North China University of Science and Technology Affiliated Hospital, Tangshan, Hebei, China (People's Republic), ¹⁴The First Xiangya Hospital of Central South University, Changsha, Hunan, China (People's Republic), ¹⁵Tangshan Gongren Hospital, Tangshan, Hebei, China (People's Republic), ¹⁶Huizhou First Hospital, Huizhou, Guangdong, China (People's Republic), ¹⁷Guangdong Province Traditional Chinese Medical Hospital, Guangzhou, Guangdong, China (People's Republic), ¹⁸The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China (People's Republic), ¹⁹The First People's Hospital of Foshan, Foshan, Guangdong, China (People's Republic), ²⁰Shanghai Gothic Internet Technology Co., Ltd, Shanghai, China (People's Republic), ²¹Shanghai Gothic Internet Technology Co., Ltd., Shanghai, Shanghai, China (People's Republic), ²²Shanghai Gothic Internet Technology Co., Ltd, Shanghai, Shanghai, China (People's Republic), ²³Shanghai Gothic Internet Technology Co., Ltd., shanghai, China (People's Republic)
Background/Purpose: Ankylosing Spondylitis Disease Activity Score (ASDAS) is adopted to evaluate the degree of disease activity and the inflammatory response in AS patients. ASDAS score ≤…
Abstract Number: 619 • 2019 ACR/ARP Annual Meeting
Relation of Therapies for Ankylosing Spondylitis to Risk of Total Hip and Knee Arthroplasty
Rachael Stovall¹, Christine Peloquin ², David Felson ³, Tuhina Neogi ² and Maureen Dubreuil ⁴, ¹Boston Medical Center, Boston, MA, ²Boston University School of Medicine, Boston, MA, ³Boston University School of Medicine, Department of Rheumatology, Boston, ⁴Boston University School of Medicine, Boston
Background/Purpose: Ankylosing spondylitis (AS) is an inflammatory arthritis that predominantly affects the axial skeleton, but commonly affects peripheral joints as well. Peripheral joint involvement often…
Abstract Number: 1505 • 2019 ACR/ARP Annual Meeting
Persistence with Etanercept in Patients with Ankylosing Spondylitis or Psoriatic Arthritis in Germany: A Real-World Analysis
Xenofon Baraliakos¹, Denis Poddubnyy ², Frank Behrens ³, Cinzia Curiale ⁴, Miriam Tarallo ⁴, Ana Cristina Hernandez Daly ⁵, Olaf Behmer ⁶, Joseph Cappelleri ⁷, Nicholas Hudson ⁸ and Christen Gray ⁸, ¹Rheumatology Department, Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Bochum, Germany, ²Charité - Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany, ³Rheumatology Goethe-University Frankfurt & Fraunhofer IME-TMP, Frankfurt, Germany, ⁴Pfizer Inc., Rome, Italy, ⁵Pfizer Inc., Athens, Greece, ⁶Pfizer Inc., Berlin, Germany, ⁷Pfizer Inc, Groton, CT, ⁸IQVIA, London, United Kingdom
Background/Purpose: Ankylosing spondylitis (AS) and psoriatic arthritis (PsA) treatment includes biologics, prescribed on a long-term basis. As persistence data from real-world practice are limited, the…
Abstract Number: 2210 • 2019 ACR/ARP Annual Meeting
Relationship Between Structural Spine Involvement and the Scanographic Bone Attenuation Coefficient of L1 in a Population of 73 Patients with Ankylosing Spondylitis
Marine Fauny¹, Frank VERHOEVEN ², Edem Allado ¹, Eliane Albuisson ³, Caroline Morizot ¹, Astrid Pinzano-Watrin ⁴, Isabelle Chary-Valckenaere ³ and Damien Loeuille ⁵, ¹CHRU Nancy, VANDOEUVRE, France, ²CHU Besancon, BESANCON, France, ³Centre Hospitalier Universitaire de Nancy, VANDOEUVRE, France, ⁴IMoPA. UMR 7365 CNRS, Vandoeuvre, France, ⁵Rheumatology, Nancy University Hospital and and UMR 7365 CNRS-UL IMoPA, Université de Lorraine, VANDOEUVRE, France
Background/Purpose: Thoracic and/or thoraco-abdomino-pelvic (TAP) Computed Tomography (CT) may be performed during the follow up of patients with ankylosing spondylitis (AS) and are able to…
Abstract Number: 581 • 2019 ACR/ARP Annual Meeting
Allograft Inflammatory factor-1 Drives Th17 Like Pathologic Signature and Predict Poor Response to TNF Inhibitor in Ankylosing Spondylitis
Jeong Seok Lee¹, Eunyoung Lee ², Ji Yong Choi ³, Yeong-Wook Song ⁴, Eui-Cheol Shin ¹ and Eun Young Lee ², ¹Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea, ²Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea, Seoul, Republic of Korea, ³Seoul National University College of Medicine, Seoul, Republic of Korea, ⁴Seoul National University Hospital, Seoul, Republic of Korea
Background/Purpose: Ankylosing spondylitis (AS) is an inflammatory disease that commonly treated with TNF inhibitors for controlling active inflammation. To predict treatment response to TNF inhibitors…
Abstract Number: 620 • 2019 ACR/ARP Annual Meeting
Arterial Elasticity by 2 Dimensional Circumferential Strain and Beta Stiffness Index in Patients with Ankylosing Spondylitis
Helena DElia¹, Lucy Law ¹, Karin Bengtsson ², Mats Geijer ³, Stefan Soderberg ⁴ and Per Lindqvist ⁵, ¹Department of Public Health and Clinical Medicine, Rheumatology, Umeå, Sweden, ²Department of Inflammation and Rheumatology Research, Göteborg, Sweden, ³Department of Radiology, Institute of Clinical Sciences, Göteborg, Sweden, ⁴Department of Public Health and Clinical Medicine, Medicine,, Umeå, Sweden, ⁵Department of Surgical and Perioperative Sciences, Clinical Physiology, Umeå, Sweden
Background/Purpose: Ankylosing spondylitis (AS) is associated with elevated risk of cardiovascular disease (CVD) and increased mortality. Arterial stiffness is associated with atherosclerosis and CV events.…
Abstract Number: 1509 • 2019 ACR/ARP Annual Meeting
Impact of Age and Disease Duration on the Response to IL-17A Inhibitor (Secukinumab) Treatment in Ankylosing Spondylitis: Pooled Results from the Phase 3 MEASURE Studies
Atul Deodhar¹, Philip Mease ², Paula Machado ³, Xiangyi Meng ³, Vibeke Strand ⁴ and Marina Magrey ⁵, ¹Oregon Health & Science University, Portland, OR, ²Swedish Medical Center/Providence St Joseph Health, and University of Washington, Seattle, WA, ³Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁴Division of Immunology/Rheumatology, Stanford University, Stanford, CA, ⁵Division of Rheumatology, The MetroHealth System and School of Medicine, Case Western Reserve University, Cleveland, OH
Background/Purpose: Ankylosing spondylitis (AS), a chronic inflammatory disease involving the sacroiliac joints and spine, is associated with pain, stiffness, disability, and reduced quality of life.1,2…
Abstract Number: 2211 • 2019 ACR/ARP Annual Meeting
What Are the Consequences of Spinal Ankylosis on the Bone Trabecular Fragility Assessed on CT- scan in Patients with Ankylosing Spondylitis?
Marine Fauny¹, Caroline Morizot ¹, Edem Allado ¹, Frank VERHOEVEN ², Eliane Albuisson ³, Astrid Pinzano-Watrin ⁴, Isabelle Chary-Valckenaere ³ and Damien Loeuille ⁵, ¹CHRU Nancy, VANDOEUVRE, France, ²CHU Besancon, BESANCON, France, ³Centre Hospitalier Universitaire de Nancy, VANDOEUVRE, France, ⁴IMoPA. UMR 7365 CNRS, Vandoeuvre, France, ⁵Rheumatology, Nancy University Hospital and and UMR 7365 CNRS-UL IMoPA, Université de Lorraine, VANDOEUVRE, France
Background/Purpose: Computed Tomography (CT) is sometimes performed during the follow up of patients with ankylosing spondylitis (AS) to screen comorbidities or complications. Thoracic or thoraco-abdomino-pelvic…
Abstract Number: 583 • 2019 ACR/ARP Annual Meeting
A Biomarker of Type VI Collagen Degradation (C6M) Is Associated with Changes in ASDAS MRI Measures of Inflammation in Patients with Axial Spondyloarthritis During TNF Inhibitor Therapy
Signe Holm Nielsen¹, Anne Bay-Jensen ², Mikkel Østergaard ³, Anne Siebuhr ⁴, Morten Karsdal ⁵, inge Juul Sørensen ⁶, Ulrich Weber ⁷, Anne Gitte Loft ⁸, Gina Kollerup ⁹, Gorm Thamsborg ⁹, Ole Rintek Madsen ¹⁰, Jakob Møller ¹¹ and Susanne Juhl Pedersen ¹², ¹Nordic Bioscience/Technical University of Denmark, Herlev, Denmark, ²Nordic Bioscience, Herlev, Denmark, ³Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark, ⁴Nordic Bioscience, Herlev, ⁵Nordic Bioscience, Copenhagen, Denmark, ⁶Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, Glostrup, Denmark, ⁷Danish Hospital for Rheumatic Diseases, University Hospital of Southern Denmark, Sonderborg, Denmark, ⁸Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, Århus, Denmark, ⁹Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Hovedstaden, Denmark, ¹⁰Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Denmark, ¹¹Department of Radiology, Herlev and Gentofte University Hospital, Herlev, Denmark, Copenhagen, Denmark, ¹²Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, Copenhagen, Hovedstaden, Denmark
Background/Purpose: Axial spondyloarthritis (AxSpa) is characterized by inflammation in the sacroiliac joints and spine and associated with extracellular matrix (ECM) remodelling of affected tissues. Type…
Abstract Number: 625 • 2019 ACR/ARP Annual Meeting
Associations of Work-Related Abilities with Disability in Ankylosing Spondylitis
Kanika Monga¹, MinJae Lee ², Michael Ward ³, Michael Weisman ⁴, Lianne Gensler ⁵, Mariko Ishimori ⁶, Amirali Tahanan ², Mohammad Rahbar ², Matthew Brown ⁷, Logan Oliver ¹, Soudabeh Daliri ¹, John Reveille ⁸ and Mark Hwang ², ¹University of Houston-McGovern Medical School, HOUSTON, TX, ²University of Texas-McGovern Medical School, Houston, TX, ³NIAMS, Bethesda, MD, ⁴David Geffen School of Medicine at UCLA, Los Angeles, CA, ⁵University San Francisco California, San Francisco, CA, ⁶Cedars-Sinai Medical Center, Los Angeles, CA, ⁷Queensland University of Technology, Queensland, Australia, ⁸University of Texas McGovern Medical School, Houston
Background/Purpose: Withdrawal from the workforce is 3.1 times higher in patients with Ankylosing Spondylitis (AS) compared to the general population [Boonen A, et al. 2001]. Functional…
Abstract Number: 1517 • 2019 ACR/ARP Annual Meeting
Effect of Long-Term Treatment with Secukinumab on Cardio-Metabolic Profile in Patients with Active Ankylosing Spondylitis and Psoriatic Arthritis: Pooled 3 Year Analysis
Iain McInnes¹, Dafna Gladman ², Atul Deodhar ³, Corinne Miceli-Richard ⁴, Peter Nash ⁵, Naveed Sattar ⁶, Nehal Mehta ⁷, Darren Asquith ⁸, Jianyuan Wang ⁹, Hanno Richards ⁹, Luminita Pricop ¹⁰ and Abhijit Shete ⁹, ¹Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom, ²Toronto Western Hospital, Toronto, Canada, Toronto, ON, Canada, ³Oregon Health & Science University, Portland, OR, ⁴Paris Descartes University, Department of Rheumatology - Hôpital Cochin, Assistance Publique - Hôpitaux de Paris, Paris, France, ⁵University of Queensland, Brisbane, Queensland, Australia, ⁶Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, United Kingdom, ⁷National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA, Bethesda, MD, ⁸Novartis Pharmaceuticals UK Limited, Surrey, United Kingdom, ⁹Novartis Pharma AG, Basel, Switzerland, ¹⁰Novartis Pharmaceuticals Corporation, East Hanover, NJ
Background/Purpose: Systemic inflammation may influence cardio-metabolic profiles and increases the risk of CV disorders in ankylosing spondylitis (AS) and psoriatic arthritis (PsA) patients (pts)1. Treatment…
Abstract Number: 2460 • 2019 ACR/ARP Annual Meeting
Frailty in Ankylosing Spondylitis, Psoriatic Arthritis, and Rheumatoid Arthritis: Data from a National Claims Database
Sarah Lieber¹, Mangala Rajan ², Sebastian E. Sattui ¹, Geyanne Lui ³, Sergio Schwartzman ⁴, Lisa Mandl ⁴ and Iris Navarro-Millan ², ¹Hospital for Special Surgery, New York, ²Weill Cornell Medicine, New York, ³Weill-Cornell Medicine, New York, NY, ⁴Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, New York, NY
Background/Purpose: Frailty, a state of decreased homeostatic reserve, is associated with increased disability and mortality, independent of age. Frailty has been evaluated in large datasets…
Abstract Number: 584 • 2019 ACR/ARP Annual Meeting
Radiographic Association of Hip and SI Joints in Ankylosing Spondylitis Patients
Juyeon Kang¹, Seoung Wan Nam ², Hyo-Kyung Sung ³, Kyung Bin Joo ⁴, Bon San Koo ⁵, Seunghun Lee ⁴ and Tae-Hwan Kim ¹, ¹Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, ²Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea, ³Hanyang University Hospital for Rheumatic Diseases, Seoul, ⁴Dertment of Radiology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Republic of Korea, ⁵Department of Internal Medicine, Inje University Seoul Paik Hospital, Inje University College of Medicine, Seoul, Republic of Korea
Background/Purpose: The modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS) is a representative tool for assessing radiographic progression in spine of ankylosing spondylitis (AS) patients. However,…
Abstract Number: 626 • 2019 ACR/ARP Annual Meeting
Are There Really Differences Between Non-radiographic and Radiographic Axial Spondyloarthritis? Data from the Spanish Atlas
Marco Garrido-Cumbrera¹, Jordi Gratacós ², Eduardo Collantes ³, Pedro Zarco ⁴, Carlos Sastre ⁵, Sergio Sanz-Gómez ⁶ and Victoria Navarro-Compán ⁷, ¹Health & Territory Research, Universidad de Sevilla, Seville, Spain, Sevilla, ²Hospital Universitari Parc Taulí, Sabadell, I3PT, UAB, Spain, Sabadell, Spain, ³Reina Sofia University Hospital, Spain. Maimonides Biomedical Research Institute of Cordoba (IMIBIC), University of Cordoba, Cordova, Spain, Cordova, Spain, ⁴Hospital Universitario Fundación Alcorcón, Madrid, Spain, Madrid, Spain, ⁵Novartis Spain, Barcelona, Spain, Barcelona, Spain, ⁶Health & Territory Research (HTR), Universidad de Sevilla, Seville, Spain, Seville, Spain, ⁷University Hospital La Paz, IdiPaz, Madrid, Spain
Background/Purpose: Most research studies support the fact that both, radiographic and non-radiographic axial spondyloarthritis (r-axSpA and nr-axSpA), share similar clinical characteristics and equivalent burden of…
Abstract Number: 1519 • 2019 ACR/ARP Annual Meeting
Predicting Response to Biologic Therapy in Patients with Axial Spondyloarthritis (axSpA)
Gareth Jones¹, Linda Dean ¹, Ejaz Pathan ² and Gary Macfarlane ¹, ¹University of Aberdeen, Aberdeen, United Kingdom, ²Toronto Western Hospital, Toronto, Canada
Background/Purpose: In axial spondyloarthritis (axSpA), the clinical benefits of TNF inhibition (TNFi) are well documented although, by design, most studies report average benefits in groups…

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].