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Abstracts tagged "Ankylosing spondylitis (AS)"

  • Abstract Number: 1306 • ACR Convergence 2020

    High Prevalence of Previously Undiagnosed Axial Spondyloarthritis in Patients Referred with Anterior Uveitis and Chronic Back Pain

    Rianne van Bentum1, Frank Verbraak2, Sanne Wolf3, Maarten Boers4, Stevie Tan5 and Irene van der Horst-Bruinsma1, 1Department of Rheumatology, Amsterdam UMC, location VU University Medical Centre, Amsterdam, Netherlands, 2Amsterdam UMC, location VU University Medical Centre, Amsterdam, Netherlands, 3Amsterdam University Medical Center location VUmc, Amsterdam, Netherlands, 4Amsterdam Rheumatology and immunology Center | Reade and Amsterdam UMC, Amsterdam, Netherlands, 5Amsterdam University Medical Center, Amsterdam, Netherlands

    Background/Purpose: To reduce the diagnostic delay in axial spondyloarthritis (axSpA), Rheumatology and Ophthalmology guidelines recommend to refer patients with acute anterior uveitis (AAU) and chronic…
  • Abstract Number: 1357 • ACR Convergence 2020

    Comparative Efficacy of Janus Kinase Inhibitors and TNF Inhibitors in Ankylosing Spondylitis: A Network Meta-Analysis

    Adela Castro1, Jesus Diaz2, Guillermo Quiceno3 and John Cush4, 1UT Southwestern, Dallas, TX, 2Universidad de los Andes, Dallas, TX, 3UT Southwestern Medical Center, Dallas, TX, 4University of Texas Southwestern Medical School, Dallas, TX

    Background/Purpose: Active ankylosing spondylitis (AS) has been associated with poor quality of life and work disability in up to 50% of patients (1). There is…
  • Abstract Number: 1863 • ACR Convergence 2020

    Clinical History as Tool for Diagnosis and Classification of Patients with Ankylosing Spondylitis (Axial Spondyloarthritis): Evidence from a 35-Year Follow-up Family Study of a Swiss Cohort

    Sjef van der Linden1, Zhixiu Li2, Matthew Brown3, Peter Villiger4, Heinz Baumberger5, Hermine Zandwijk6 and Muhammad Khan7, 1Department of Rheumatology, Immunology and Allergology, University of Bern, Inselspital, Bern, Switzerland, Mortroux, Belgium, 2Queensland University of Technology (QUT), Translational Genomics Group, School of Biomedical Sciences, Institute of Health and Biomedical Innovation, Translational Research Institute, Princess Alexandra Hospital, Brisbane, Qld, Australia, Brisbane, Queensland, Australia, 3Guy's and St Thomas, NHS Foundation Trust and King's College London NIHR Biomedical Research Centre, King's College London, London, United Kingdom, London, United Kingdom, 4Department of Rheumatology, Immunology and Allergology, University of Bern, Inselspital, Switzerland, Bern, Switzerland, 5Retired, Flims, Tajikistan, 6Retired, Mortroux, Belgium, 7Case Western Reserve University, Cleveland OH, Westlake, OH

    Background/Purpose: Lack of sensitivity or specificity of symptoms may induce uncertainty in diagnosis and classification of AS/axSpA. We investigated if balanced sensitivity and specificity of…
  • Abstract Number: 1891 • ACR Convergence 2020

    Impact of Utilising Smart Phone Application in Ankylosing Spondylitis: SMART- as Study

    Ashit Syngle1, Nidhi Garg2 and Kanchan Chauhan1, 1Healing Touch City Clinic, Chandigarh, Chandigarh, India, 2Chitkara University, Rajpura, Punjab, India

    Background/Purpose: Ankylosing spondylitis (AS) is a chronic inflammatory disease that primarily affects the axial skeleton and characterized by inflammatory back pain, leading to decreased mobility,…
  • Abstract Number: 0038 • ACR Convergence 2020

    Protein Biomarkers May Differentiate Responders and Non-Responders to Adalimumab, a Tumour Necrosis Factor Inhibitor, in Ankylosing Spondylitis Patients – The Bioefficacy SpA Study

    Ana Fernandes1, Atlas Mashayekhi Sardoo2, Miguel Bernardes3, Patrícia Pinto4, Helena Santos5, João Lagoas Gomes6, José Tavares-Costa7, José A. P. da Silva8, João Madruga-Dias9, Alexandra Bernardo10, Jean-Charles Gaillard11, Lúcia Domingues12, Sara Maia12, Jean Armengaud11, Jaime C. Branco13, Ana Varela Coelho14 and Fernando Pimentel-Santos15, 11.Instituto de Tecnologia Química e Biológica, Universidade NOVA de Lisboa; 2.Universidade de Trás-os-Montes e Alto Douro, Vila Real, Portugal, Oeiras, Portugal, 23. CEDOC, NOVA Medical School, Faculdade de Ciências Médicas da Universidade NOVA de Lisboa, Lisboa, Portugal, Lisbon, Portugal, 34.Centro Hospitalar de S. João (Rheumatology Department) , Porto, Portugal, Porto, Portugal, 45. Centro Hospitalar de Vila Nova de Gaia/Espinho (Rheumatology Department), Vila Nova de Gaia, Portugal, Vila Nova de Gaia, Portugal, 56.Instituto Português de Reumatologia (Rheumatology Department), Lisboa, Portugal, Lisboa, Portugal, 67.Hospital Egas Moniz (CHLO) (Rheumatology Department), Lisboa, Portugal, Lisboa, Portugal, 78.Unidade Local de Saúde do Alto Minho (Rheumatology Department), Ponte de Lima, Portugal, Ponte de Lima, Portugal, 89.Centro Hospitalar e Universitário Coimbra (Rheumatology Department), Coimbra, Portugal, Coimbra, Portugal, 910.Centro Hospital Médio Tejo (Rheumatology Department), Torres Novas, Portugal, Dublin, Ireland, 105.Centro Hospitalar de Vila Nova de Gaia/Espinho (Rheumatology Department), Vila Nova de Gaia, Portugal, Vila Nova de Gaia, Portugal, 1111.Centre d énergie atomique (Laboratoire Innovations technologiques pour la Détection et le Diagnostic (Li2D), Service de Pharmacologie et Immunoanalyse (SPI)), Avignon, France, Avignon, France, 123.CEDOC, NOVA Medical School. Faculdade de Ciências Médicas da Universidade NOVA de Lisboa, Lisboa, Portugal, Lisboa, Portugal, 133.CEDOC, NOVA Medical School, Faculdade de Ciências Médicas da Universidade NOVA de Lisboa, Lisboa, Portugal; 7.Hospital Egas Moniz (CHLO) (Rheumatology Department), Lisboa, Portugal, Lisboa, Portugal, 141.Instituto de Tecnologia Química e Biológica, Universidade NOVA de Lisboa, Oeiras, Portugal, Oeiras, Portugal, 153.CEDOC, NOVA Medical School, Faculdade de Ciências Médicas da Universidade NOVA de Lisboa, Lisboa, Portugal; 7.Hospital Egas Moniz (CHLO) (Rheumatology Department), Lisboa, Portugal, Lisbon, Portugal

    Background/Purpose: Axial Spondyloarthritis (AS) is amongst the most common forms of inflammatory arthritis. Widely used in the treatment of axSpA, adalimumab is an engineered antibody…
  • Abstract Number: 0448 • ACR Convergence 2020

    Disease-related factors associated to atherosclerotic disease in axial spondyloarthritis. A mutlicenter study with 806 patients.

    Inigo Gonzalez-Mazon1, Ivan Ferraz-Amaro2, Javier Rueda-Gotor3, Lara Sanchez-Bilbao4, David Martinez-Lopez5, Mario Agudo-Bilbao3, Fernanda Genre6, Sara Remuzgo-Martínez6, Veronica Pulito-Cueto6, Alfonso Corrales7, Leticia Lera-Gómez6, Virginia Portilla6, Vanesa Calvo-Río3, Cristina Mata8, Vanesa Hernández-Hernández9, Santos Castañeda10, Esther Francisca Vicente-Rabaneda11, C Fernandez-Carballido12, M Paz Martínez-Vidal13, David Castro-Corredor14, Joaquín Anino-Fernández14, Juan Carlos Quevedo-Abeledo15, Carlos Rodríguez-Lozano16, C. Fernandez-Diaz17, Esther Montes-Perez18, María Luz García Vivar,19, Eva Galínez-Agirregoikoa19, Javier Llorca20, Raquel López-Mejías6, Chamaida Plasencia21, Diana Peiteado22, Alejandro Balsa-Criado23, Nuria Barbarroja24, Lourdes Ladehesa-Pineda25, Rafaela Ortega-Castro26, Eduardo Collantes-Estévez25, Ricardo Blanco4 and Miguel Ángel González-Gay27, 1Hospital Universitario Marques de Valdecilla, Bezana, Spain, 2Division of Rheumatology. Hospital Universitario de Canarias. Spain., Santa Cruz de Tenerife, Spain, 3H.U. Marques de Valdecilla, Santander, Spain, 4Hospital Universitario Marques de Valdecilla, Santander, Spain, 5Hospital Universitario Marques de Valdecilla, Santander (SPAIN), Spain, 6Research group on Genetic Epidemiology and Atherosclerosis in Systemic Diseases and in Metabolic bone Diseases of the Musculoskeletal System, IDIVAL, Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain, 7Research group on genetic epidemiology and atherosclerosis in systemic diseases and in metabolic bone diseases of the musculoskeletal system, IDIVAL; and Department of Rheumatology, Hospital Universitario Marqués de Valdecilla, Santander, Spain, 8Hospital de Laredo, Santander, Spain, 9Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, 10Princesa University Hospital, Universidad Autónoma, Madrid, Madrid, Spain, 11Hospital Universitario de la Princesa, IIS-Princesa, UAM, Madrid, Madrid, Spain, 12H San Juan, Alicante, Spain, 13Hospital General Universitario de Alicante, Alicante, Spain, 14Hospital General Universitario de Ciudad Real, Ciudad Real, Spain, 15Hospital Dr. Negrín, Las Palmas de Gran Canaria, Spain, 16Hospital Universitario de Gran Canaria Dr. Negrín, Las Palmas de Gran Canaria, Spain, 17H. Marqués de Valdecilla, Madrid, Spain, 18Diagnóstico Médico Cantabria (DMC), Santander, Spain, 19Hospital Universitario Basurto, Bilbao, Spain, 20School of Medicine, University of Cantabria, and CIBER Epidemiología y Salud Pública (CIBERESP), Santander, Spain, 21Rheumatology, La Paz University Hospital-IdiPAZ, madrid, Spain, 22Hospital Universitario La Paz-IdiPaz, Madrid, Spain, 23HOSPITAL UNIVERSITARIO LA PAZ, madrid, Spain, 24Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Cordoba, Spain, 25Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Córdoba, Spain, 26Hospital Universitario Reina Sofía, Córdoba, Spain, 27Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain

    Background/Purpose: Cardiovascular (CV) mortality and morbidity is increased in ankylosing spondylitits (AS) due to a process of accelerated atherosclerosis. The disease-related factors involved in this…
  • Abstract Number: 1309 • ACR Convergence 2020

    Prevalence of Undiagnosed Axial Spondyloarthritis Among Patients with Inflammatory Bowel Disease: A Secondary Care Cross-Sectional Study

    Chong Seng Edwin Lim1, Mark Tremelling1, Louise Hamilton1, Alexander MacGregor1, Tom Turmezei1, Matthew Kim1 and Karl Gaffney2, 1Norfolk and Norwich University Hospital, Norwich, United Kingdom, 2Norfolk and Norwich University Hospital NHS Foundation Trust, Norfolk, United Kingdom

    Background/Purpose: Axial spondyloarthritis (axSpA) is closely related to inflammatory bowel disease (IBD), however contemporary data on the burden of hidden disease in the IBD population…
  • Abstract Number: 1359 • ACR Convergence 2020

    Targeted Serum Proteomic Analysis Following Upadacitinib Treatment in Ankylosing Spondylitis Shows Robust Suppression of Innate and Adaptive Immune Pathways with Tissue Repair Modulation

    Thierry Sornasse1, In-Ho Song2, Timothy Radstake3 and Dennis McGonagle4, 1AbbVie Immunology Clinical Development, Redwood City, 2AbbVie Inc., North Chicago, IL, 3AbbVie Immunology Clinical Development, North Chicago, 4The University of Leeds, Leeds Institute for Rheumatic and Musculoskeletal Medicine, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK, Leeds, United Kingdom

    Background/Purpose: Upadacitinib (UPA), an oral JAK inhibitor selective for JAK1, demonstrated efficacy in patients with active ankylosing spondylitis (AS) with an inadequate response (IR) to…
  • Abstract Number: 1867 • ACR Convergence 2020

    Two-Year Diagnostic Consistency in Patients with Chronic Back Pain Suspected of Axial Spondyloarthritis in Protocolised Follow-up: Data from the Spondyloarthritis Caught Early Cohort

    Anne Boel1, Miranda van Lunteren2, Karen Fagerli3, Ulf Lindström4, Roberta Ramonda5, Marleen van de Sande6, Désirée van der Heijde7 and Floris van Gaalen8, 1Leiden University Medical Centre, Hooge Zwaluwe, Netherlands, 2Leiden University Medical Centre, Weesp, Netherlands, 3Diakonhjemmet Hospital, Oslo, Norway, 4Department of Rheumatology and inflammation research, Institute of Medicine, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden., Gothenburg, Sweden, 5University of Padova, Padova, Italy, 6Amsterdam UMC, AMC/University of Amsterdam, Department of Rheumatology and Clinical Immunology, Amsterdam Infection & Immunity Institute and Amsterdam Rheumatology and Immunology Center (ARC), Amsterdam, Netherlands, 7Leiden University Medical Center, Leiden, Netherlands, 8Leiden University Medical Center (LUMC), Leiden, Netherlands

    Background/Purpose: A diagnosis of (early) axial spondyloarthritis (axSpA) is based on pattern recognition, which can be challenging and may change over time. The aim of…
  • Abstract Number: 1892 • ACR Convergence 2020

    Pattern and Influential Factors in Promoting Treat-to-Target (T2T) for F Ankylosing Spondylitis (AS) Patients with the App of Smart System of Disease Management (SSDM): A Cohort Study from China

    Jing Xue1, Hongzhi Wang2, Hongbin Li3, Hui Song4, Yasong Li5, Xiaofei Shi6, Hongjun Zhao7, Feng Wei8, Bing Wu9, Hui Xiao10, Yuhua Jia9, Fei Xiao9 and Huaxiang Wu1, 1The Second Affiliated Hospital of Zhejiang University school of Medicine, Hangzhou, China (People's Republic), 2The First Hospital of Jiaxing, Jiaxing, China (People's Republic), 3The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, China (People's Republic), 4Beijing Jishuitan Hospital, Beijing, China (People's Republic), 5Zhejiang Provincial People's Hospital, Hangzhou, China (People's Republic), 6The First Affiliated Hospital of Henan University of science and technology, Luoyang, China (People's Republic), 7Xiangya Hospital of Central South University, Changsha, China (People's Republic), 8Jiangmen Central Hospital Affiliated Jiangmen Hospital of Sun Yat-Sen University, Jiangmen, China (People's Republic), 9Shanghai Gothic Internet Technology Co., Ltd., Shanghai, China (People's Republic), 10Shanghai Gothic Internet Technology Co., Ltd., Shanghai, Shanghai, China (People's Republic)

    Background/Purpose: Ankylosing Spondylitis Disease Activity Score (ASDAS) is adopted to evaluate the degree of disease activity and the inflammatory response in AS patients. ASDAS score…
  • Abstract Number: 0080 • ACR Convergence 2020

    Understanding Ankylosing Spondylitis –

    Arnd Kleyer1, Milena Pachowsky2, Louis Schuster1, Larissa Valor-Mendez3, Georg Schett4, Axel Hueber5 and David Simon1, 1Department of Internal Medicine 3, Friedrich-Alexander University (FAU) Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Bayern, Germany, 2Department of Orthopedic and Trauma Surgery, FAU Erlangen-Nuremberg and Universitätsklinikum Erlangen, Erlangen, Germany, 3Department of Internal Medicine 3, Rheumatology and Immunology, University Hospital Erlangen, Erlangen, Bayern, Germany, 4Friedrich-Alexander-Universität Erlangen- Nuremberg, Erlangen, Germany, 5Sozialstiftung Bamberg, Sektion Rheumatologie, Bamberg, Germany

    Background/Purpose: Rheumatology is underrepresented in the medical training of students in Germany. [1] Tools and methods are needed to inspire young students for specialist training…
  • Abstract Number: 0455 • ACR Convergence 2020

    HLA-B27 and Host Immune Response: Lessons from Reactive Arthritis

    Sophie Wojcik1, Davina Morris2, Gillian Fitzgerald3, Steve Ramkissoon4, Nigil Haroon2 and Robert Inman5, 1UHN, Montreal, QC, Canada, 2University of Toronto, Toronto, ON, Canada, 3Toronto Western Hospital, Toronto, ON, Canada, 4UHN, Toronto, ON, Canada, 5University Health Network, Toronto, ON, Canada

    Background/Purpose: The natural history of reactive arthritis (ReA) remains poorly understood. Certain patients with ReA will go on to develop a chronic course while others…
  • Abstract Number: 1310 • ACR Convergence 2020

    Gut Microbiome Changes Are Different Between Ankylosing Spondylitis and Inflammatory Bowel Disease, and Correlate with Disease Activity in Both Diseases

    Peter Sternes1, Laurel Brett2, Julie Phipps3, Francesco Ciccia4, Erika de Guzman3, Mark Morrison5, Gerald Holtmann6, Eva Klingberg7, Carolyn McIvor2, Helena Forsblad-d'Elia8 and Matthew Brown9, 1Institute for Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia, Brisbane, Queensland, Australia, 2Department of Gastroenterology, Logan Hospital, Brisbane, Queensland, Australia, 3Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia, 4Dipartimento di Medicina di Precisione, Università della Campania L. Vanvitelli, Naples, Naples, Campania, Italy, 5University of Queensland Diamantina Institute, University of Queensland, Brisbane, Queensland, Australia, 6Department of Gastrenterology, Princess Alexandra Hospital, Brisbane, Queensland, Australia, 7Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Vastra Gotaland, Sweden, 8Department of Public Health and Clinical Medicine/Rheumatology, Umeå University, Umeå, Vasterbottens Lan, Sweden, 9Guy's and St Thomas, NHS Foundation Trust and King's College London NIHR Biomedical Research Centre, King's College London, London, United Kingdom, London, United Kingdom

    Background/Purpose: Multiple studies have confirmed that the gut and stool microbiome in ankylosing spondylitis (AS) and inflammatory bowel disease (IBD) are distinct from healthy controls,…
  • Abstract Number: 1362 • ACR Convergence 2020

    BASDAI Guided Treat-to-target Tapering of Tumor Necrosis Factor Inhibitors in Axial Spondyloarthritis: Results of the Retrospective TAPAS Study

    Nathan den Broeder1, Michelle Mulder1, Mark Wenink1, Alfons den Broeder1, Lise Verhoef2, Frank van den Hoogen1 and C.A.J Michielsens1, 1Sint Maartenskliniek, Nijmegen, Netherlands, 2Sint Maartenskliniek, Nijmegen, Gelderland, Netherlands

    Background/Purpose: Tumor Necrosis Factor inhibitors (TNFi) have proven to be safe and effective in the treatment of axial spondyloarthritis (axSpA). However, they carry some disadvantages,…
  • Abstract Number: 1868 • ACR Convergence 2020

    Comparison of Quality of Life Between Chronic Back Pain Patients with and Without a Diagnosis of Axial Spondyloarthritis After 2-Year Protocolised Follow-up: Data from the Spondyloarthritis Caught Early Cohort

    Anne Boel1, Miranda van Lunteren2, Karen Fagerli3, Sofia Exarchou4, Roberta Ramonda5, Marleen van de Sande6, Désirée van der Heijde7 and Floris van Gaalen8, 1Leiden University Medical Centre, Hooge Zwaluwe, Netherlands, 2Leiden University Medical Centre, Weesp, Netherlands, 3Diakonhjemmet Hospital, Oslo, Norway, 4Rheumatology, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden, Malmo, Sweden, 5University of Padova, Padova, Italy, 6Amsterdam UMC, AMC/University of Amsterdam, Department of Rheumatology and Clinical Immunology, Amsterdam Infection & Immunity Institute and Amsterdam Rheumatology and Immunology Center (ARC), Amsterdam, Netherlands, 7Leiden University Medical Center, Leiden, Netherlands, 8Leiden University Medical Center (LUMC), Leiden, Netherlands

    Background/Purpose: The aim of this study was to compare quality of life (QoL) between chronic back pain (CBP) patients with and without a diagnosis of…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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