Abstracts tagged "Ankylosing spondylitis (AS)"

Abstract Number: 1869 • ACR Convergence 2020
“Rheum to Diagnosis”: Uncovering Impediments to Accurate Diagnosis of Non-radiographic Axial Spondylarthritis (nr-axSpA)
Sonam Kiwalkar¹, Atul Deodhar¹ and Richard Howard², ¹Oregon Health & Science University, Portland, OR, ²Spondylitis Association of America, Van Nuys, CA
Background/Purpose: In the US, there is up to a 14-year delay in axSpA diagnosis, which is likely greater for nr-axSpA.1 Impediments to timely diagnosis of…
Abstract Number: 1894 • ACR Convergence 2020
Use of Facebook and Electronic Patient Portal to Identify Axial Spondyloarthritis in Patients with Chronic Back Pain
Yuliya Afinogenova¹, Swetha Alexander², Andrew Haims³ and Abhijeet Danve⁴, ¹Yale University, Orange, CT, ²University of Connecticut, New Haven, ³Yale University, New Haven, CT, ⁴Yale University, Rocky Hill, CT
Background/Purpose: Delay in diagnosis of Axial Spondyloarthritis (axSpA) remains a significant unmet need and can be partially attributed to lack of timely rheumatology referral. Current…
Abstract Number: 0154 • ACR Convergence 2020
Treatment Decision Making Among Axial Spondyloarthritis Patients: Real-World Data from the ArthritisPower Registry
William Nowell¹, Theresa Hunter², Kelly Gavigan³, Jeffrey R Curtis⁴, William Malatestinic⁵, Rebecca Bolce⁵, Jeffrey Lisse⁵, Andris Kronbergs⁵, Carol Himelein⁵, Jennifer Walker⁶ and Jessica Walsh⁷, ¹Global Healthy Living Foundation, New York City, NY, ²Eli Lilly and Company, Indianapolis, ³Global Healthy Living Foundation, Upper Nyack, NY, ⁴Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁵Eli Lilly and Company, Indianapolis, IN, ⁶Global Health Living Foundation, New York City, NY, ⁷University of Utah School of Medicine, George E. Wahlen Veteran Affairs Medical Center, Salt Lake City, UT
Background/Purpose: Biologic disease-modifying antirheumatic drug (bDMARD) therapy has been shown to be effective in the treatment of axial spondyloarthritis (axSpA).1,2 Little is understood about axSpA…
Abstract Number: 0876 • ACR Convergence 2020
Gender Differences in Baseline Clinical Characteristics Among Patients with Ankylosing Spondylitis and Non-radiographic Axial Spondyloarthritis: Data from 3 Randomized Ixekizumab Controlled Trials
Marina Magrey¹, Kurt de Vlam², Rebecca Bolce³, Soyi Liu-Leage⁴, Danting Zhu⁴, Theresa Hunter³, David Sandoval³ and Irene van der Horst-Bruinsma⁵, ¹Case Western Reserve University School of Medicine, Cleveland, OH, ²Department of Rheumatology, University of Leuven, Belgium, Leuven, Belgium, ³Eli Lilly and Company, Indianapolis, ⁴Eli Lilly and Company, Indianapolis, IN, ⁵Department of Rheumatology, Amsterdam UMC, location VU University Medical Centre, Amsterdam, Netherlands
Background/Purpose: Ixekizumab (IXE), an anti-interleukin-17A monoclonal antibody, has demonstrated superior efficacy to placebo in the treatment of patients with axial spondyloarthritis (axSpA) (Dougados M et…
Abstract Number: 1315 • ACR Convergence 2020
Exploring the Prevalence and Factors Associated with Fatigue in Axial Spondyloarthritis in a Multiethnic Asian Cohort in Singapore
Wei Ze Lim¹, Warren Fong², Yu Heng Kwan³ and Ying Ying Leung², ¹Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Singapore, ²Department of Rheumatology and Immunology, Singapore General Hospital, Singapore, Singapore, Singapore, ³Duke-NUS Medical School, Singapore, Singapore, Singapore
Background/Purpose: Fatigue is a cardinal symptom of axial spondyloarthritis (axSpA) that poses management challenges. Data on fatigue amongst Asian patients with axSpA is limited. Ethnicity…
Abstract Number: 1365 • ACR Convergence 2020
Machine Learning-based Berlin Scoring of Magnetic Resonance Images of the Spine in Patients with Ankylosing Spondylitis: Analysis of Data from a Phase 3 Trial with Secukinumab
Amir Jamaludin¹, Rhydian Windsor¹, Sarim Ather¹, Timor Kadir¹, Andrew Zisserman¹, Juergen Braun², Lianne Gensler³, Pedro Machado⁴, Mikkel Østergaard⁵, Denis Poddubnyy⁶, Thibaud Coroller⁷, Brian Porter⁷, Shephard Mpofu⁸ and Aimee Readie⁷, ¹University of Oxford, Oxford, United Kingdom, ²Rheumazentrum Ruhrgebiet and Ruhr-University, 44649 Herne, Germany, ³University of California San Francisco, San Francisco, CA, ⁴University College London, London, United Kingdom, ⁵Rigshospitalet, University of Copenhagen, Copenhagen, Denmark, ⁶Charité – Universitätsmedizin Berlin, Berlin, Germany, ⁷Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁸Novartis Pharma AG, Basel, Switzerland
Background/Purpose: Magnetic resonance imaging (MRI) offers a non-invasive and objective method of early diagnosis and classification, monitoring disease burden and treatment response for patients (pts)…
Abstract Number: 1871 • ACR Convergence 2020
Comparison of Work Productivity Outcomes Between Chronic Back Pain Patients with and Without a Diagnosis of Axial Spondyloarthritis After 2-Year Protocolised Follow-Up: Data from the Spondyloarthritis Caught Early Cohort
Anne Boel¹, Miranda van Lunteren², Karen Fagerli³, Roberta Ramonda⁴, Sofia Exarchou⁵, Marleen van de Sande⁶, Floris van Gaalen⁷ and Désirée van der Heijde⁸, ¹Leiden University Medical Centre, Hooge Zwaluwe, Netherlands, ²Leiden University Medical Centre, Weesp, Netherlands, ³Diakonhjemmet Hospital, Oslo, Norway, ⁴University of Padova, Padova, Italy, ⁵Rheumatology, Department of Clinical Sciences Malmö, Lund University, Malmö, Sweden, Malmo, Sweden, ⁶Amsterdam UMC, AMC/University of Amsterdam, Department of Rheumatology and Clinical Immunology, Amsterdam Infection & Immunity Institute and Amsterdam Rheumatology and Immunology Center (ARC), Amsterdam, Netherlands, ⁷Leiden University Medical Center (LUMC), Leiden, Netherlands, ⁸Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: The aim of this study was to compare work-productivity and activity impairment outcomes after two-year follow-up between chronic back pain (CBP) patients with and…
Abstract Number: 1897 • ACR Convergence 2020
Trends in Hospitalizations for Vertebral Compression Fractures in Ankylosing Spondylitis: Data from the National Inpatient Sample 2001-2014
Anish Paudel¹, Rashmi Dhital², Dilli Poudel³, Anthony Donato¹ and Paras Karmacharya⁴, ¹Reading Hospital and Medical Center, West Reading, PA, ²Reading Hospital and Medical Center, West Reading, ³University of Pennsylvania, Philadelphia, PA, ⁴Mayo Clinic, Rochester MN, ROCHESTER, MN
Background/Purpose: Ankylosing spondylitis (AS) is a chronic inflammatory disease predominantly affecting the spine, leading to syndesmophyte formation, ankylosis, and osteoporosis. These factors have been associated…
Abstract Number: 603 • 2019 ACR/ARP Annual Meeting
Are the Modified New York and ASAS Criteria Interchangeable in the Classification of Patients with Spondyloarthritis with Radiographic Sacroiliitis?
Anne Boel¹, Anna Moltó ², Désirée van der Heijde ³, Adrian Ciurea ⁴, Maxime Dougados ⁵, Lianne Gensler ⁶, Maria José Santos ⁷, Eugenio de Miguel ⁸, Denis Poddubnyy ⁹, Martin Rudwaleit ¹⁰, Astrid van Tubergen ¹¹, Floris van Gaalen ³ and Sofia Ramiro ¹², ¹Leiden University Medical Centre, Leiden, Netherlands, ²Paris Descartes University, Cochin Hospital, Rheumatology department, Paris, France, ³Leiden University Medical Center, Leiden, Netherlands, ⁴University Hospital Zürich, Zürich, Switzerland, ⁵Cochin Hospital, Paris, France, ⁶University San Francisco California, San Francisco, CA, ⁷Rheumatology department, Hospital Garcia de Orta, Almada, Portugal, ⁸Rheumatology Department, Hospital Universitario La Paz, Madrid, Spain, ⁹Charité - Universitätsmedizin Berlin and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany, ¹⁰Klinikum Bielefeld, Charité Berlin, Gent University, Bielefeld, Germany, ¹¹Maastricht University Medical Centre and Care and Public Health Research Institute (CAPHRI), Maastricht, Netherlands, ¹²Leiden University Medical Center and Zuyderland Medical Centre, Leiden, Netherlands
Background/Purpose: Patients with axial spondyloarthritis (axSpA) with radiographic sacroiliitis may be classified using the modified New York (mNY) criteria as ankylosing spondylitis and using the…
Abstract Number: 1082 • 2019 ACR/ARP Annual Meeting
Cancer Risk in Patients with Ankylosing Spondylitis: A Nationwide Population-based Dynamic Cohort Study from Korea
Eunyoung Lee¹, Kyung-Do Han ², Yeong-Wook Song ³ and Eun Young Lee ¹, ¹Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea, Seoul, Republic of Korea, ²Department of Biostatistics, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Seoul, Republic of Korea, ³Seoul National University Hospital, Seoul, Republic of Korea
Background/Purpose: The aim of this study is to determine the risk of overall malignancy and site-specific cancer in ankylosing spondylitis (AS) patients compared with patients…
Abstract Number: 1544 • 2019 ACR/ARP Annual Meeting
Predictors of Response, Adverse Events and Treatment Retention in Ankylosing Spondylitis Patients Treated with Golimumab in a Prospective, Observational Registry
Proton Rahman ¹, Ariel Masetto ², Michelle Teo ³, Pauline Boulos ⁴, Dalton Sholter ⁵, Suneil Kapur ⁶, Emmanouil Rampakakis ⁷, Meagan Rachich ⁸, Odalis Asin-Milan ⁸, Allen Lehman ⁸ and Francois Nantel⁸, ¹Memorial University, Newfoundland, NL, Canada, ²Université de Sherbrooke, Sherbrooke, QC, Canada, ³Balfour Medical Clinic, Penticton, BC, Canada, ⁴McMaster University, Hamilton, ON, Canada, ⁵Rheumatology Associates, Edmonton, AB, Canada, ⁶University of Ottawa, Ottawa, ON, Canada, ⁷JSS Medical Research, Montreal, Canada, ⁸Janssen Inc., Toronto, ON, Canada
Background/Purpose: The Biologic Treatment Registry Across Canada (BioTRAC) was a prospective, observational registry that enrolled ankylosing spondylitis (AS) (radiographic axial SpA) patients treated with subcutaneous…
Abstract Number: 608 • 2019 ACR/ARP Annual Meeting
Prevalence of Radiographic Entheseal Lesions at the Hip and Pelvic Region in Patients with Ankylosing Spondylitis versus Controls
Freke Wink¹, Thomas Diemel ², Suzanne Arends ² and Anneke Spoorenberg ², ¹Medical Center Leeuwarden, Leeuwarden, Netherlands, ²University Medical Center Groningen, Groningen, Netherlands
Background/Purpose: Enthesitis is one of the features of ankylosing spondylitis (AS). High prevalence of structural and inflammatory ultrasound lesions of peripheral entheses are found in…
Abstract Number: 1087 • 2019 ACR/ARP Annual Meeting
Golimumab Improves Work Productivity and Activity and Quality of Life in Patients with Rheumatoid Arthritis (RA), Ankylosing Spondylitis (AS) and Psoriatic Arthritis (PsA): Final Results from a Non-Interventional Study in Germany (GO-ART)
Klaus Krüger¹, Sven Remstedt ², Astrid Thiele ³ and Ines Klaudius ⁴, ¹Medical Centre of Rheumatology, Munich, Germany, ²Rheuma Praxis Berlin, Berlin, Germany, ³Krankenhaus St. Josef Wuppertal, Wuppertal, Germany, ⁴MSD Sharp & Dohme GmbH, Haar, Germany
Background/Purpose: Golimumab (GLM) has shown its efficacy and tolerability in various randomized clinical trials. Systemic data for GLM regarding health-economic parameters in daily clinical practice…
Abstract Number: 1551 • 2019 ACR/ARP Annual Meeting
Does Retention and Remission Rates to 2nd and 3rd TNF Inhibitors in Patients with Axial Spondyloarthritis Depend on the Reason from Withdrawal to the Previous Treatment? – Real World Data from 12 European Countries in the EuroSpA Research Collaboration
Lykke Midtbøll Ørnbjerg ¹, Cecilie Heegaard Brahe¹, Anne Gitte Loft ², Johan Askling ³, Adrian Ciurea ⁴, Herman Mann ⁵, Servet Akar ⁶, Eirik Kristianslund ⁷, Dan Nordström ⁸, Maria José Santos ⁹, Catalin Codreanu ¹⁰, Manuel Pombo-Suarez ¹¹, Ziga Rotar ¹², Bjorn Gudbjornsson ¹³, Daniela DiGuiseppe ¹⁴, Michael J. Nissen ¹⁵, Karel Pavelka ⁵, Soner Senel ¹⁶, Joe Sexton ¹⁷, Kari K. Eklund ¹⁸, Anabela Barcelos ¹⁹, Ruxandra IONESCU ²⁰, Carlos Sánchez-Piedra ²¹, Matija Tomsic ²², Arni Jon Geirsson ²³, Irene van der Horst-Bruinsma ²⁴, Gary Macfarlane ²⁵, Florenzo Iannone ²⁶, Brigitte Michelsen ¹, Lise Hyldstrup ²⁷, Niels Steen Krogh ²⁸, Merete Lund Hetland ²⁹ and Mikkel Østergaard ³⁰, ¹EuroSpA Coordinating Center, Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Glostrup, Denmark, ²Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, Århus, Denmark, ³Karolinska Institutet, Stockholm, Sweden, ⁴University Hospital Zürich, Zürich, Switzerland, ⁵Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Prague, Czech Republic, Prague 2, Czech Republic, ⁶Izmir Katip Celebi University, Faculty of Medicine, Division of Rheumatology, İzmir, Turkey, ⁷Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway., Oslo, Norway, ⁸Department of Medicine, ROB-FIN, Helsinki University Hospital and Helsinki University, Helsinki, Finland., Helsinki, Finland, ⁹Rheumatology department, Hospital Garcia de Orta, Almada, Portugal, ¹⁰Center of Rheumatic Diseases, University of Medicine and Pharmacy, Bucharest, Romania., Bucharest, Romania, ¹¹Rheumatology Unit, Clinical University Hospital of Santiago de Compostela,, Santiago, Spain, ¹²UMC LJUBLJANA, DPT. OF RHEUMATOLOGY, LJUBLJANA, Slovenia, ¹³Centre for Rheumatology Research, Landspitali and Faculty of Medicine, University of Iceland, Reykjavik, Iceland, ¹⁴Clinical Epidemiology Division, Dept of Medicine Solna, Karolinska Institutet,, Stockholm, Sweden, ¹⁵University Hospital Geneva, Geneva, Switzerland, ¹⁶Division of Rheumatology, Erciyes University School of Medicine, Kayseri, Turkey, Kayseri, Turkey, ¹⁷Diakonhjemmet Hospital, Dept. of Rheumatology, Oslo, Norway, ¹⁸ROB-FIN registry, Department of Medicine, Helsinki University and University Hospital, Helsinki, Finland, ¹⁹Centro Hospitalar Baixo Vouga | iBemed, University of Aveiro, Aveiro, Portugal, ²⁰SPITALUL CLINIC SFANTA MARIA, Bucharest, ²¹Research Unit, Spanish Society of Rheumatology, Madrid, Spain, ²²Department of Rheumatology, University Medical Center Ljubljana, Slovenia, Ljubljana, Slovenia, ²³Centre for Rheumatology Research, University Hospital and Faculty of Medicine, Reykjavik, Iceland, ²⁴Amsterdam University Medical Center, Amsterdam, Netherlands, ²⁵University of Aberdeen, Aberdeen, United Kingdom, ²⁶Department of Emergency and Transplantation , Rheumatology Unit, University Hospital of Bari, Bari, Italy., Bari, Italy, ²⁷Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet Glostrup, Denmark, Copenhagen, Denmark, ²⁸Zitelab / DANBIO, Copenhagen, Denmark, ²⁹DANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark, ³⁰Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark
Background/Purpose: Tumour necrosis factor inhibitors (TNFi) are efficacious in patients with axial spondyloarthritis (axSpA), but still some patients switch to a different TNFi because of…
Abstract Number: 611 • 2019 ACR/ARP Annual Meeting
Retina of Ankylosing Spondylitis Patients Shows Early Signs of Atherosclerotic Disease in Comparison with Healthy Controls
Rianne van Bentum¹, Milad Baniaamam ², Buket Kinaci-Tas ³, Aleid van de Kreeke ⁴, Merve Kocyigit ¹, Pieter Jelle Visser ⁵, Erik Serné ⁶, Frank Verbraak ⁷, Mike Nurmohamed ⁸ and Irene van der Horst-Bruinsma ¹, ¹Amsterdam Rheumatology and immunology Center, Rheumatology, Amsterdam University Medical Center location VUmc, Amsterdam, Amsterdam, Netherlands, ²Amsterdam Rheumatology and immunology Center, Rheumatology, Reade, Amsterdam|Amsterdam Rheumatology and immunology Center, Rheumatology, Amsterdam University Medical Center location VUmc, Amsterdam, Amsterdam, Netherlands, ³Opthalmology dpt., Amsterdam University Medical Center, location AMC, Amsterdam, Amsterdam, Netherlands, ⁴Ophthalmology dpt., Amsterdam University Medical Center, location VUmc, Amsterdam, Amsterdam, Netherlands, ⁵Dpt. of Clinical Chemistry, Amsterdam University Medical Center, Amsterdam, Amsterdam, Netherlands, ⁶Dpt. Internal Medicine, Amsterdam University Medical Center, location VUmc, Amsterdam, Amsterdam, Netherlands, ⁷Ophthalmology dpt., Amsterdam University Medical Center, Amsterdam, Amsterdam, Netherlands, ⁸Amsterdam Rheumatology and immunology Center location Reade and Amsterdam UMC location VU medical center, Amsterdam, Netherlands
Background/Purpose: Chronic systemic inflammation in patients with ankylosing spondylitis (AS) contributes to the development of cardiovascular disease (CVD). Early recognition of microvascular changes could improve…

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