Abstracts tagged "Ankylosing spondylitis (AS)"

Abstract Number: 1025 • ACR Convergence 2022
Entheseal Biopsy Approach: An Ultrasound-guided Method for Retrieval of Entheseal Tissue from Psoriatic Arthritis Patients
Maria Gabriella Raimondo¹, Milena Pachowsky¹, Cong Xu¹, Simon Rauber¹, Koray Tascilar¹, Hannah Labinsky², Mario Vogg¹, Mina Saad Aziz Saad¹, David Simon¹, Juergen Rech³, Alina Soare¹, Lars Braeuer⁴, Arnd Kleyer¹, Georg Schett⁵ and Andreas Ramming¹, ¹Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-UniversityErlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, ²Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, 91054 Erlangen, Germany; Deutsches Zentrum Immuntherapie, Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany, ³University Clinic Erlangen, Erlangen, Germany, ⁴Institute of Anatomy, Chair II, Friedrich-Alexander-Universitat Erlangen-Nurnberg, Erlangen, Germany, ⁵Universitätsklinikum Erlangen, Erlangen, Germany
Background/Purpose: Enthesitis as hallmark feature of psoriatic arthritis (PsA) has been mostly addressed through clinical assessment and imaging evaluation, such as MRI or musculoskeletal ultrasound.…
Abstract Number: 1355 • ACR Convergence 2022
Relationships Between Work Productivity, Activity Impairment, and Select Patient-Reported Outcomes in Patients with Ankylosing Spondylitis: A Post Hoc Analysis of Two Placebo-Controlled Trials
Marina Magrey¹, James Cheng-Chung WEI², Arne Yndestad³, Andrew Bushmakin⁴, Joseph Cappelleri⁴, Oluwaseyi Dina⁵ and Atul Deodhar⁶, ¹Case Western Reserve University, University Hospitals, Richfield, OH, ²Chung Shan Medical University Hospital, Taichung, Taiwan, ³Pfizer Inc, Oslo, Norway, ⁴Pfizer Inc, Groton, CT, ⁵Pfizer Inc, New York, NY, ⁶Oregon Health & Science University, Portland, OR, USA, Portland, OR
Background/Purpose: Patients (pts) with AS often experience impaired work productivity.1 In pts with AS receiving tofacitinib (oral Janus kinase inhibitor), improvements were observed in work…
Abstract Number: 2257 • ACR Convergence 2022
MRI Spinal Lesions in Patients Without MRI or Radiographic Lesions in the Sacroiliac Joints Typical of Axial Spondyloarthritis
Walter P Maksymowych¹, Mikkel Østergaard², Xenofon Baraliakos³, Pedro Machado⁴, Susanne J. Pedersen⁵, Ulrich Weber⁶, Iris Eshed⁷, Manouk de Hooge⁸, Joachim Sieper⁹, Denis Poddubnyy¹⁰, Martin Rudwaleit¹¹, Désirée van der Heijde¹², Robert Landewé¹³ and Robert G Lambert¹⁴, ¹Department of Medicine, University of Alberta, Edmonton, AB, Canada, ²Rigshospitalet, University of Copenhagen, Glostrup, Denmark, ³Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ⁴University College London, London, United Kingdom, ⁵Rigshospitalet, University of Copenhagen, Copenhagen, Denmark, ⁶Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, ⁷Sheba Medical Center, Tel Aviv, Israel, ⁸Ghent University Hospital, Luxembourg, Luxembourg, ⁹Charité - Universitätsmedizin, Berlin, Berlin, Germany, ¹⁰Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, Berlin, Germany, ¹¹University of Bielefeld, Klinikum Bielefeld, Bielefeld; Germany Klinikum Bielefeld and Charité Berlin, Germany, and Gent University, Gent, Belgium, ¹²Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands, ¹³Amsterdam University Medical Center, Meerssen, Netherlands, ¹⁴University of Alberta, Edmonton, AB, Canada
Background/Purpose: There is limited data as to the frequency of spinal lesions on MRI in patients without MRI or radiographic features typical of sacroiliac joint…
Abstract Number: 0394 • ACR Convergence 2022
In Radiographic Axial Spondyloarthritis Spinal Mobility Measures Correlate Well with the Whole Spine CT Syndesmophyte Score (CTSS)
Rosalinde Stal¹, Sofia Ramiro¹, Xenofon Baraliakos², Juergen Braun³, Monique Reijnierse¹, Rosaline van den Berg¹, Désirée van der Heijde⁴ and floris van Gaalen¹, ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ³Rheumazentrum Ruhrgebiet, Herne, Germany, ⁴Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands
Background/Purpose: The modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS) is the best validated and widely used method for assessing radiographic progression in axial spondyloarthritis (axSpA)…
Abstract Number: 0421 • ACR Convergence 2022
Efficacy and Safety of Tofacitinib in Patients with Ankylosing Spondylitis by Prior bDMARD Treatment: Analysis of a Phase 3 Trial
Atul Deodhar¹, Helena Marzo-Ortega², Joseph Wu³, Cunshan Wang³, Oluwaseyi Dina⁴, Keith S Kanik³, Lara Fallon⁵ and Lianne Gensler⁶, ¹Oregon Health & Science University, Portland, OR, USA, Portland, OR, ²Leeds Teaching Hospitals Trust and University of Leeds, Leeds, United Kingdom, ³Pfizer Inc, Groton, CT, ⁴Pfizer Inc, New York, NY, ⁵Pfizer Inc, Montréal, QC, Canada, ⁶Department of Medicine, Division of Rheumatology, University of California San Francisco, San Francisco, CA
Background/Purpose: Prior exposure to biologic (b)DMARD therapy of patients (pts) with AS may influence treatment response.1-3 Tofacitinib is an oral JAK inhibitor for the treatment…
Abstract Number: 1029 • ACR Convergence 2022
Virtual Assessment in Axial Spondyloarthritis: Validation of Video Observation of Spinal Metrology
Laura Passalent¹, Sareh Keshavarzi¹, Robert Inman¹ and Nigil Haroon², ¹University Health Network, Toronto, ON, Canada, ²Schroeder Arthritis Institute, University Health Network; University of Toronto, Toronto, ON, Canada
Background/Purpose: A shift to virtual clinical encounters was required because of the COVID-19 pandemic. To date, there have been few studies exploring the utility of…
Abstract Number: 1423 • ACR Convergence 2022
Long-Term Treatment with Golimumab Is a Safe Treatment Option Regardless of Risk Factors in Patients with Rheumatoid Arthritis, Psoriatic Arthritis, and Axial Spondyloarthritis: Results from a Real-World Canadian Setting
Regan Arendse¹, Proton Rahman², Philip Baer³, Derek Haaland⁴, Dalton Sholter⁵, Odalis Asin-Milan⁶, Meagan Rachich⁷, Emmanouil Rampakakis⁸, A. Marilise Marrache⁹ and Allen J. Lehman¹⁰, ¹Community Rheumatology Care, Saskatoon, Canada, ²Memorial University, St. John's, NL, Canada, ³Baer Weinberg MPC, Scarborough, ON, Canada, ⁴The Waterside Clinic, Oro Medonte, ON, Canada, ⁵University of Alberta, Edmonton, AB, Canada, ⁶Janssen Canada, Laval, QC, Canada, ⁷Janssen Inc., Guelph, ON, Canada, ⁸McGill University, Department of Pediatrics and JSS Medical Research, Montréal, QC, Canada, ⁹Janssen Inc., Dollard-des-Ormeaux, QC, Canada, ¹⁰Janssen Inc., Toronto, ON, Canada
Background/Purpose: Golimumab (GLM), a tumor necrosis factor inhibitor (TNFi), has demonstrated efficacy and a favorable safety profile in inflammatory rheumatic diseases. Recent safety studies with…
Abstract Number: 2258 • ACR Convergence 2022
Relative Frequencies of the Spectrum of MRI Lesions in the Sacroiliac Joints of Healthy Individuals and Patients with Non-Specific Back Pain: What Is the Impact of Increasing Age?
Ulrich Weber¹, Susanne Pedersen², Mikkel Østergaard³, Pedro Machado⁴, Xenofon Baraliakos⁵, Robert G Lambert⁶ and Walter P Maksymowych⁷, ¹Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, ²Rigshospitalet, København, Denmark, ³Rigshospitalet, University of Copenhagen, Glostrup, Denmark, ⁴University College London, London, United Kingdom, ⁵Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ⁶University of Alberta, Edmonton, AB, Canada, ⁷Department of Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Previous studies of patients with axial spondyloarthritis (axSpA) have demonstrated that certain MRI structural lesions in the sacroiliac joints (SIJ), notably erosions, has high…
Abstract Number: 0396 • ACR Convergence 2022
Validity of Syndesmophyte Detection on Low Dose Computed Tomography in Patients with Radiographic Axial Spondyloarthritis
Rosalinde Stal¹, Sofia Ramiro¹, Xenofon Baraliakos², Juergen Braun³, Monique Reijnierse¹, Rosaline van den Berg¹, floris van Gaalen¹ and Désirée van der Heijde⁴, ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ³Rheumazentrum Ruhrgebiet, Herne, Germany, ⁴Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands
Background/Purpose: Low-dose Computed Tomography (ldCT), assessed with the CT syndesmophyte score (CTSS) in the whole spine, has been shown to detect more progression in the…
Abstract Number: 0422 • ACR Convergence 2022
Efficacy and Safety of Secukinumab in the Treatment of Axial Spondyloarthritis: Real-Life Data from TURKBIO Cohort
Semih Gulle¹, Ali Karakas¹, Gercek Can², Soner Senel³, Sedat Capar⁴, Huseyin ediz dalkilic⁵, Servet Akar⁶, Suleyman Serdar Koca⁷, Abdurrahman Tufan⁸, Ayten Yazici⁹, Sema Yilmaz¹⁰, Nevsun Inanc¹¹, Merih Birlik¹, Dilek Solmaz¹², Ayse Cefle⁹, Berna Goker¹³, Servet Yolbas¹⁴, Niels Steen Krough¹⁵, Neslihan Yilmaz¹⁶, Sukran Erten¹⁷, Cemal Bes¹⁸, Ozgul Soysal¹⁹, Mehmet Akif Ozturk¹³, Seminur Haznedaroglu¹³, Sule Yavuz¹⁶, Haner Direskeneli²⁰, Fatoş Onen²¹ and Ismail Sari²², ¹Dokuz Eylul University School of Medicine Division of Rheumatology, Izmir, Turkey, ²Dokuz Eylul University School of Medicine Division of Rheumatology, Istanbul, Turkey, ³Erciyes University School of Medicine Division of Rheumatology, Kayseri, Turkey, ⁴Dokuz Eylul University Faculty of Science Department of Statistics, Izmir, Turkey, ⁵Uludag University School of Medicine Division of Rheumatology, Bursa, Turkey, ⁶Izmir Katip Celebi University School of Medicine, Izmir, Turkey, ⁷Firat University School of Medicine Division of Rheumatology, Elazıg, Turkey, ⁸Gazi University Medical Faculty Hospital, Istanbul, Turkey, ⁹Kocaeli University School of Medicine Division of Rheumatology, Kocaeli, Turkey, ¹⁰Selcuk University School of Medicine Division of Rheumatology, Konya, Turkey, ¹¹Marmara University School of Medicine, Division of Rheumatology, Istanbul, Turkey, ¹²Kâtip Celebi University School of Medicine Division of Rheumatology, Izmir, Turkey, ¹³Gazi University School of Medicine Division of Rheumatology, Ankara, Turkey, ¹⁴Inonu University School of Medicine Division of Rheumatology, Malatya, Turkey, ¹⁵Zitelab Aps, Kopenhag, Denmark, ¹⁶Demiroglu Bilim University School of Medicine Division of Rheumatology, Istanbul, Turkey, ¹⁷Yildirim Beyazit University School of Medicine Division of Rheumatology, Ankara, Turkey, ¹⁸Basaksehir Cam and Sakura ospital, Division of Rheumatology, Istanbul, Turkey, ¹⁹Celal Bayar University, School of Medicine Division of Rheumatology, Manisa, Turkey, ²⁰Marmara University School of Medicine Division of Rheumatology, Istanbul, Turkey, ²¹Dokuz Eylul University, Faculty of Medicine, Rheumatology, İzmir, Turkey, ²²Dokuz Eylul University School of Medicine Division of Rheumatology, İzmir, Turkey
Background/Purpose: In this study, we aimed to evaluate the results of secukinumab treatment in patients with Axial Spondyloarthritis (AxSpA) who were enrolled in the TURKBIO…
Abstract Number: 1030 • ACR Convergence 2022
Diagnostic Usefulness of Anti-PPM1A-IgM in Patients with Ankylosing Spondylitis
Yeo jin lee¹, Eun-Ju Lee², Soo Min Ahn², Seokchan Hong², Ji Seon Oh³, Chang Keun Lee², Bin Yoo² and Yong Gil Kim², ¹Asan medical center, Seoul, Republic of Korea, ²Department of Rheumatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea, Seoul, Republic of Korea, ³Department of Information Medicine, Big Data Research Center, Asan Medical Center, Seoul, Republic of Korea
Background/Purpose: Ankylosing spondylitis (AS) has been known to have auto-inflammatory nature, hence, the efficacy of autoantibodies is low. However, studies on autoantibodies are ongoing, with…
Abstract Number: 1425 • ACR Convergence 2022
Treatment Persistence and Switching Patterns of ABP 501 (AMGEVITA®) in German Patients with Rheumatic Diseases
Ran Jin¹, Silvia Kruppert², Florian Scholz², Marc Hammer², Greg Kricorian¹, David Collier³ and Jonathan Kay⁴, ¹Amgen, Inc., Thousand Oaks, CA, ²IQVIA, Frankfurt, Germany, ³Amgen Inc., Simi Valley, CA, ⁴Division of Rheumatology, Department of Medicine, UMass Chan Medical School and UMass Memorial Medical Center, Worcester, MA
Background/Purpose: ABP 501 is the first adalimumab (ADA) biosimilar approved by the European Medical Association and the Food and Drug Administration for the treatment of…
Abstract Number: PP07 • ACR Convergence 2022
Remissions and Vigilance
Michael Scepaniak, Cockeysville, MD
Background/Purpose: I've been diagnosed with spondyloarthritis (SpA) for a little more than 7 1/2 years. That diagnosis was preceded by roughly 9 months of significant…
Abstract Number: 0399 • ACR Convergence 2022
ASAS Recommendations for Requesting and Reporting Imaging in Patients with Suspected Axial Spondyloarthritis
Torsten Diekhoff¹, Iris Eshed², Chiara Giraudo³, Hildrun Haibel⁴, Kay-Geert Hermann⁵, Manouk de Hooge⁶, Lennart Jans⁷, Anne Jurik⁸, Robert G Lambert⁹, Pedro Machado¹⁰, Walter P Maksymowych¹¹, Michael Mallinson¹², Helena Marzo-Ortega¹³, Victoria Navarro-Compán¹⁴, Susanne Pedersen¹⁵, Mikkel Østergaard¹⁶, Monique Reijnierse¹⁷, Martin Rudwaleit¹⁸, Fernando Andres Sommerfleck¹⁹, Ulrich Weber²⁰, Xenofon Baraliakos²¹ and Denis Poddubnyy²², ¹Charité – Universitätsmedizin Berlin, Berlin, Germany, ²Sheba Medical Center, Tel Aviv, Israel, ³University of Padova, Padova, Italy, ⁴Charité - Universitätsmedizin, Berlin, Berlin, Germany, ⁵Charité - Universitätsmedizin Berlin, Berlin, Germany, ⁶Ghent University Hospital, Luxembourg, Luxembourg, ⁷Ghent University Hospital, Ghent, Belgium, ⁸Aarhus University Hospital, Aarhus, Denmark, ⁹University of Alberta, Edmonton, AB, Canada, ¹⁰University College London, London, United Kingdom, ¹¹Department of Medicine, University of Alberta, Edmonton, AB, Canada, ¹²ASIF Axial Spondyloarthritis International Federation, London, United Kingdom, ¹³Leeds Teaching Hospitals Trust and University of Leeds, Leeds, United Kingdom, ¹⁴Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, ¹⁵Rigshospitalet, København, Denmark, ¹⁶Rigshospitalet, University of Copenhagen, Glostrup, Denmark, ¹⁷Leiden University Medical Center, Leiden, Netherlands, ¹⁸University of Bielefeld, Klinikum Bielefeld, Bielefeld; Germany Klinikum Bielefeld and Charité Berlin, Germany, and Gent University, Gent, Belgium, ¹⁹Sanatorio Julio Mendez, Buenos Aires, Argentina, ²⁰Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, ²¹Rheumazentrum Ruhrgebiet Herne, Herne, Germany, ²²Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, Berlin, Germany
Background/Purpose: Clinicians face uncertainties in their daily practice when requesting imaging for patients with suspicion of axial spondyloarthritis (axSpA) or producing a report because requirements…
Abstract Number: 0424 • ACR Convergence 2022
The Efficacy and Safety of CT-P13 as First-line and Subsequent-line Therapy in Patients with Ankylosing Spondylitis: Real-life Data from TURKBIO Cohort
Sadettin Uslu¹, Semih Gulle¹, Gercek Can², Soner Senel³, Sedat Capar⁴, Huseyin ediz dalkilic⁵, Servet Akar⁶, Suleyman Serdar Koca⁷, Abdurrahman Tufan⁸, Ayten Yazici⁹, Sema Yilmaz¹⁰, Nevsun Inanc¹¹, Merih Birlik¹, Dilek Solmaz¹², Ayse Cefle⁹, Berna Goker¹³, Servet Yolbas¹⁴, Niels Steen Krough¹⁵, Neslihan Yilmaz¹⁶, Sukran Erten¹⁷, Cemal Bes¹⁸, Ozgul Soysal¹⁹, Mehmet Akif Ozturk¹³, Seminur Haznedaroglu¹³, Sule Yavuz¹⁶, Haner Direskeneli²⁰, Fatoş Onen²¹ and Ismail Sari²², ¹Dokuz Eylul University School of Medicine Division of Rheumatology, Izmir, Turkey, ²Dokuz Eylul University School of Medicine Division of Rheumatology, Istanbul, Turkey, ³Erciyes University School of Medicine Division of Rheumatology, Kayseri, Turkey, ⁴Dokuz Eylul University Faculty of Science Department of Statistics, Izmir, Turkey, ⁵Uludag University School of Medicine Division of Rheumatology, Bursa, Turkey, ⁶Izmir Katip Celebi University School of Medicine, Izmir, Turkey, ⁷Firat University School of Medicine Division of Rheumatology, Elazıg, Turkey, ⁸Gazi University Medical Faculty Hospital, Istanbul, Turkey, ⁹Kocaeli University School of Medicine Division of Rheumatology, Kocaeli, Turkey, ¹⁰Selcuk University School of Medicine Division of Rheumatology, Konya, Turkey, ¹¹Marmara University School of Medicine, Division of Rheumatology, Istanbul, Turkey, ¹²Kâtip Celebi University School of Medicine Division of Rheumatology, Izmir, Turkey, ¹³Gazi University School of Medicine Division of Rheumatology, Ankara, Turkey, ¹⁴Inonu University School of Medicine Division of Rheumatology, Malatya, Turkey, ¹⁵Zitelab Aps, Kopenhag, Denmark, ¹⁶Demiroglu Bilim University School of Medicine Division of Rheumatology, Istanbul, Turkey, ¹⁷Yildirim Beyazit University School of Medicine Division of Rheumatology, Ankara, Turkey, ¹⁸Basaksehir Cam and Sakura ospital, Division of Rheumatology, Istanbul, Turkey, ¹⁹Celal Bayar University, School of Medicine Division of Rheumatology, Manisa, Turkey, ²⁰Marmara University School of Medicine Division of Rheumatology, Istanbul, Turkey, ²¹Dokuz Eylul University, Faculty of Medicine, Rheumatology, İzmir, Turkey, ²²Dokuz Eylul University School of Medicine Division of Rheumatology, İzmir, Turkey
Background/Purpose: In this study, it was aimed to evaluate the long-term drug survival, efficacy and safety of infliximab biosimilar CT-P13 in Turkish patients diagnosed with…

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