ACR Meeting Abstracts

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Abstracts tagged "Ankylosing spondylitis (AS)"

  • Abstract Number: 1029 • ACR Convergence 2022

    Virtual Assessment in Axial Spondyloarthritis: Validation of Video Observation of Spinal Metrology

    Laura Passalent1, Sareh Keshavarzi1, Robert Inman1 and Nigil Haroon2, 1University Health Network, Toronto, ON, Canada, 2Schroeder Arthritis Institute, University Health Network; University of Toronto, Toronto, ON, Canada

    Background/Purpose: A shift to virtual clinical encounters was required because of the COVID-19 pandemic. To date, there have been few studies exploring the utility of…
  • Abstract Number: 1423 • ACR Convergence 2022

    Long-Term Treatment with Golimumab Is a Safe Treatment Option Regardless of Risk Factors in Patients with Rheumatoid Arthritis, Psoriatic Arthritis, and Axial Spondyloarthritis: Results from a Real-World Canadian Setting

    Regan Arendse1, Proton Rahman2, Philip Baer3, Derek Haaland4, Dalton Sholter5, Odalis Asin-Milan6, Meagan Rachich7, Emmanouil Rampakakis8, A. Marilise Marrache9 and Allen J. Lehman10, 1Community Rheumatology Care, Saskatoon, Canada, 2Memorial University, St. John's, NL, Canada, 3Baer Weinberg MPC, Scarborough, ON, Canada, 4The Waterside Clinic, Oro Medonte, ON, Canada, 5University of Alberta, Edmonton, AB, Canada, 6Janssen Canada, Laval, QC, Canada, 7Janssen Inc., Guelph, ON, Canada, 8McGill University, Department of Pediatrics and JSS Medical Research, Montréal, QC, Canada, 9Janssen Inc., Dollard-des-Ormeaux, QC, Canada, 10Janssen Inc., Toronto, ON, Canada

    Background/Purpose: Golimumab (GLM), a tumor necrosis factor inhibitor (TNFi), has demonstrated efficacy and a favorable safety profile in inflammatory rheumatic diseases. Recent safety studies with…
  • Abstract Number: 2258 • ACR Convergence 2022

    Relative Frequencies of the Spectrum of MRI Lesions in the Sacroiliac Joints of Healthy Individuals and Patients with Non-Specific Back Pain: What Is the Impact of Increasing Age?

    Ulrich Weber1, Susanne Pedersen2, Mikkel Østergaard3, Pedro Machado4, Xenofon Baraliakos5, Robert G Lambert6 and Walter P Maksymowych7, 1Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, 2Rigshospitalet, København, Denmark, 3Rigshospitalet, University of Copenhagen, Glostrup, Denmark, 4University College London, London, United Kingdom, 5Rheumazentrum Ruhrgebiet Herne, Herne, Germany, 6University of Alberta, Edmonton, AB, Canada, 7Department of Medicine, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: Previous studies of patients with axial spondyloarthritis (axSpA) have demonstrated that certain MRI structural lesions in the sacroiliac joints (SIJ), notably erosions, has high…
  • Abstract Number: 0396 • ACR Convergence 2022

    Validity of Syndesmophyte Detection on Low Dose Computed Tomography in Patients with Radiographic Axial Spondyloarthritis

    Rosalinde Stal1, Sofia Ramiro1, Xenofon Baraliakos2, Juergen Braun3, Monique Reijnierse1, Rosaline van den Berg1, floris van Gaalen1 and Désirée van der Heijde4, 1Leiden University Medical Center, Leiden, Netherlands, 2Rheumazentrum Ruhrgebiet Herne, Herne, Germany, 3Rheumazentrum Ruhrgebiet, Herne, Germany, 4Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands, Leiden, Netherlands

    Background/Purpose: Low-dose Computed Tomography (ldCT), assessed with the CT syndesmophyte score (CTSS) in the whole spine, has been shown to detect more progression in the…
  • Abstract Number: 0422 • ACR Convergence 2022

    Efficacy and Safety of Secukinumab in the Treatment of Axial Spondyloarthritis: Real-Life Data from TURKBIO Cohort

    Semih Gulle1, Ali Karakas1, Gercek Can2, Soner Senel3, Sedat Capar4, Huseyin ediz dalkilic5, Servet Akar6, Suleyman Serdar Koca7, Abdurrahman Tufan8, Ayten Yazici9, Sema Yilmaz10, Nevsun Inanc11, Merih Birlik1, Dilek Solmaz12, Ayse Cefle9, Berna Goker13, Servet Yolbas14, Niels Steen Krough15, Neslihan Yilmaz16, Sukran Erten17, Cemal Bes18, Ozgul Soysal19, Mehmet Akif Ozturk13, Seminur Haznedaroglu13, Sule Yavuz16, Haner Direskeneli20, Fatoş Onen21 and Ismail Sari22, 1Dokuz Eylul University School of Medicine Division of Rheumatology, Izmir, Turkey, 2Dokuz Eylul University School of Medicine Division of Rheumatology, Istanbul, Turkey, 3Erciyes University School of Medicine Division of Rheumatology, Kayseri, Turkey, 4Dokuz Eylul University Faculty of Science Department of Statistics, Izmir, Turkey, 5Uludag University School of Medicine Division of Rheumatology, Bursa, Turkey, 6Izmir Katip Celebi University School of Medicine, Izmir, Turkey, 7Firat University School of Medicine Division of Rheumatology, Elazıg, Turkey, 8Gazi University Medical Faculty Hospital, Istanbul, Turkey, 9Kocaeli University School of Medicine Division of Rheumatology, Kocaeli, Turkey, 10Selcuk University School of Medicine Division of Rheumatology, Konya, Turkey, 11Marmara University School of Medicine, Division of Rheumatology, Istanbul, Turkey, 12Kâtip Celebi University School of Medicine Division of Rheumatology, Izmir, Turkey, 13Gazi University School of Medicine Division of Rheumatology, Ankara, Turkey, 14Inonu University School of Medicine Division of Rheumatology, Malatya, Turkey, 15Zitelab Aps, Kopenhag, Denmark, 16Demiroglu Bilim University School of Medicine Division of Rheumatology, Istanbul, Turkey, 17Yildirim Beyazit University School of Medicine Division of Rheumatology, Ankara, Turkey, 18Basaksehir Cam and Sakura ospital, Division of Rheumatology, Istanbul, Turkey, 19Celal Bayar University, School of Medicine Division of Rheumatology, Manisa, Turkey, 20Marmara University School of Medicine Division of Rheumatology, Istanbul, Turkey, 21Dokuz Eylul University, Faculty of Medicine, Rheumatology, İzmir, Turkey, 22Dokuz Eylul University School of Medicine Division of Rheumatology, İzmir, Turkey

    Background/Purpose: In this study, we aimed to evaluate the results of secukinumab treatment in patients with Axial Spondyloarthritis (AxSpA) who were enrolled in the TURKBIO…
  • Abstract Number: 1030 • ACR Convergence 2022

    Diagnostic Usefulness of Anti-PPM1A-IgM in Patients with Ankylosing Spondylitis

    Yeo jin lee1, Eun-Ju Lee2, Soo Min Ahn2, Seokchan Hong2, Ji Seon Oh3, Chang Keun Lee2, Bin Yoo2 and Yong Gil Kim2, 1Asan medical center, Seoul, Republic of Korea, 2Department of Rheumatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea, Seoul, Republic of Korea, 3Department of Information Medicine, Big Data Research Center, Asan Medical Center, Seoul, Republic of Korea

    Background/Purpose: Ankylosing spondylitis (AS) has been known to have auto-inflammatory nature, hence, the efficacy of autoantibodies is low. However, studies on autoantibodies are ongoing, with…
  • Abstract Number: 1425 • ACR Convergence 2022

    Treatment Persistence and Switching Patterns of ABP 501 (AMGEVITA®) in German Patients with Rheumatic Diseases

    Ran Jin1, Silvia Kruppert2, Florian Scholz2, Marc Hammer2, Greg Kricorian1, David Collier3 and Jonathan Kay4, 1Amgen, Inc., Thousand Oaks, CA, 2IQVIA, Frankfurt, Germany, 3Amgen Inc., Simi Valley, CA, 4Division of Rheumatology, Department of Medicine, UMass Chan Medical School and UMass Memorial Medical Center, Worcester, MA

    Background/Purpose: ABP 501 is the first adalimumab (ADA) biosimilar approved by the European Medical Association and the Food and Drug Administration for the treatment of…
  • Abstract Number: PP07 • ACR Convergence 2022

    Remissions and Vigilance

    Michael Scepaniak, Cockeysville, MD

    Background/Purpose: I've been diagnosed with spondyloarthritis (SpA) for a little more than 7 1/2 years. That diagnosis was preceded by roughly 9 months of significant…
  • Abstract Number: 0399 • ACR Convergence 2022

    ASAS Recommendations for Requesting and Reporting Imaging in Patients with Suspected Axial Spondyloarthritis

    Torsten Diekhoff1, Iris Eshed2, Chiara Giraudo3, Hildrun Haibel4, Kay-Geert Hermann5, Manouk de Hooge6, Lennart Jans7, Anne Jurik8, Robert G Lambert9, Pedro Machado10, Walter P Maksymowych11, Michael Mallinson12, Helena Marzo-Ortega13, Victoria Navarro-Compán14, Susanne Pedersen15, Mikkel Østergaard16, Monique Reijnierse17, Martin Rudwaleit18, Fernando Andres Sommerfleck19, Ulrich Weber20, Xenofon Baraliakos21 and Denis Poddubnyy22, 1Charité – Universitätsmedizin Berlin, Berlin, Germany, 2Sheba Medical Center, Tel Aviv, Israel, 3University of Padova, Padova, Italy, 4Charité - Universitätsmedizin, Berlin, Berlin, Germany, 5Charité - Universitätsmedizin Berlin, Berlin, Germany, 6Ghent University Hospital, Luxembourg, Luxembourg, 7Ghent University Hospital, Ghent, Belgium, 8Aarhus University Hospital, Aarhus, Denmark, 9University of Alberta, Edmonton, AB, Canada, 10University College London, London, United Kingdom, 11Department of Medicine, University of Alberta, Edmonton, AB, Canada, 12ASIF Axial Spondyloarthritis International Federation, London, United Kingdom, 13Leeds Teaching Hospitals Trust and University of Leeds, Leeds, United Kingdom, 14Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, 15Rigshospitalet, København, Denmark, 16Rigshospitalet, University of Copenhagen, Glostrup, Denmark, 17Leiden University Medical Center, Leiden, Netherlands, 18University of Bielefeld, Klinikum Bielefeld, Bielefeld; Germany Klinikum Bielefeld and Charité Berlin, Germany, and Gent University, Gent, Belgium, 19Sanatorio Julio Mendez, Buenos Aires, Argentina, 20Practice Buchsbaum Schaffhausen, Schaffhausen, Switzerland, 21Rheumazentrum Ruhrgebiet Herne, Herne, Germany, 22Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, Berlin, Germany

    Background/Purpose: Clinicians face uncertainties in their daily practice when requesting imaging for patients with suspicion of axial spondyloarthritis (axSpA) or producing a report because requirements…
  • Abstract Number: 0424 • ACR Convergence 2022

    The Efficacy and Safety of CT-P13 as First-line and Subsequent-line Therapy in Patients with Ankylosing Spondylitis: Real-life Data from TURKBIO Cohort

    Sadettin Uslu1, Semih Gulle1, Gercek Can2, Soner Senel3, Sedat Capar4, Huseyin ediz dalkilic5, Servet Akar6, Suleyman Serdar Koca7, Abdurrahman Tufan8, Ayten Yazici9, Sema Yilmaz10, Nevsun Inanc11, Merih Birlik1, Dilek Solmaz12, Ayse Cefle9, Berna Goker13, Servet Yolbas14, Niels Steen Krough15, Neslihan Yilmaz16, Sukran Erten17, Cemal Bes18, Ozgul Soysal19, Mehmet Akif Ozturk13, Seminur Haznedaroglu13, Sule Yavuz16, Haner Direskeneli20, Fatoş Onen21 and Ismail Sari22, 1Dokuz Eylul University School of Medicine Division of Rheumatology, Izmir, Turkey, 2Dokuz Eylul University School of Medicine Division of Rheumatology, Istanbul, Turkey, 3Erciyes University School of Medicine Division of Rheumatology, Kayseri, Turkey, 4Dokuz Eylul University Faculty of Science Department of Statistics, Izmir, Turkey, 5Uludag University School of Medicine Division of Rheumatology, Bursa, Turkey, 6Izmir Katip Celebi University School of Medicine, Izmir, Turkey, 7Firat University School of Medicine Division of Rheumatology, Elazıg, Turkey, 8Gazi University Medical Faculty Hospital, Istanbul, Turkey, 9Kocaeli University School of Medicine Division of Rheumatology, Kocaeli, Turkey, 10Selcuk University School of Medicine Division of Rheumatology, Konya, Turkey, 11Marmara University School of Medicine, Division of Rheumatology, Istanbul, Turkey, 12Kâtip Celebi University School of Medicine Division of Rheumatology, Izmir, Turkey, 13Gazi University School of Medicine Division of Rheumatology, Ankara, Turkey, 14Inonu University School of Medicine Division of Rheumatology, Malatya, Turkey, 15Zitelab Aps, Kopenhag, Denmark, 16Demiroglu Bilim University School of Medicine Division of Rheumatology, Istanbul, Turkey, 17Yildirim Beyazit University School of Medicine Division of Rheumatology, Ankara, Turkey, 18Basaksehir Cam and Sakura ospital, Division of Rheumatology, Istanbul, Turkey, 19Celal Bayar University, School of Medicine Division of Rheumatology, Manisa, Turkey, 20Marmara University School of Medicine Division of Rheumatology, Istanbul, Turkey, 21Dokuz Eylul University, Faculty of Medicine, Rheumatology, İzmir, Turkey, 22Dokuz Eylul University School of Medicine Division of Rheumatology, İzmir, Turkey

    Background/Purpose: In this study, it was aimed to evaluate the long-term drug survival, efficacy and safety of infliximab biosimilar CT-P13 in Turkish patients diagnosed with…
  • Abstract Number: 1034 • ACR Convergence 2022

    Characterization of Non-radiographic Axial Spondyloarthritis Patients and the Burden of Disease in Routine Clinical Practice

    Kathryn Starzyk, Pam Kumparatana and roger Meng, OM1, Inc., Boston, MA

    Background/Purpose: Axial spondyloarthritis [AxSpA and particularly non-radiographic (nr)AxSpA] has one of the longest diagnostic delays in rheumatology. Although improving, lack of radiographic evidence of disease…
  • Abstract Number: 1426 • ACR Convergence 2022

    Year-two Follow-up Results of an Observational Study Conducted in Rheumatoid Arthritis, Ankylosing Spondylitis and Psoriatic Arthritis Patients Treated with Infliximab Biosimilar CT-P13 in a Real-life Setting

    Bruno Fautrel1, Maryse Assing2, Nadir Mammar2, Yves Brault2 and Hubert Marotte3, 1Sorbonne University Paris, France and Pierre Louis Institute of Epidemiology and Public Health, Paris, France, Paris, France, 2Pfizer, Paris, France, 3INSERM 1059, Saint-Etienne, France

    Background/Purpose: ReFLECT study has been carried out to investigate real life use of CT-P13, the first monoclonal antibody biosimilar to infliximab (IFX) originator.Methods: ReFLECT is…
  • Abstract Number: PP11 • ACR Convergence 2022

    Exercise as a Supportive Treatment for My Ankylosing Spondylitis

    Sara King-Dowling, Children's Hospital of Philadelphia, Philadelphia, PA

    Background/Purpose: Patients with autoimmune rheumatic diseases (ARDs) are often caught in a paradox as they experience mobility challenges, but long periods of immobility cause increased…
  • Abstract Number: 0402 • ACR Convergence 2022

    Opioid Use and Healthcare Utilization in Adults with PsA and AS

    Alexis Ogdie1, Sofia Pedro2, Jean Liew3 and Kaleb Michaud4, 1Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, 2Forward, The National Databank for Rheumatic Diseases, Wichita, KS, 3Boston University, Boston, MA, 4University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Opioid use among individuals with spondyloarthritis is common, reported to be ~20-30% in some cohorts. Data on whether this subset of patients have higher…
  • Abstract Number: 0425 • ACR Convergence 2022

    Upadacitinib Pharmacokinetics and Exposure-Response Relationships for Efficacy and Safety in Axial Spondyloarthritis – Analyses of the Phase 3 Studies (SELECT-AXIS 1 and 2)

    Sumit Bhatnagar1, Doerthe Eckert2, Sven Stodtmann2, In-Ho Song3, Peter Wung3, Wei Liu3 and Mohamed-Eslam Mohamed3, 1AbbVie, Highland Park, IL, 2AbbVie, Ludwigshafen, Germany, 3AbbVie, Inc., North Chicago, IL

    Background/Purpose: The efficacy and safety profile of 15 mg once-daily (QD) upadacitinib (UPA), an oral, reversible, JAK inhibitor has been established in axial spondyloarthritis (axSpA),…
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